Application of the reconstructed rabbit corneal epithelium model to assess the in vitro eye irritancy test of chemicals

Yakugaku Zasshi

Volumn 129, Issue 9, 2009, Pages 1113-1120

  Matsuda, Sanae ^a   Hisama, Masayoshi ^a   Shibayama, Hiroharu ^a   Itou, Norihiko ^b   Iwaki, Masahiro ^c  

^a HBC Science Research Center Co Ltd   (Japan)

^b YOKOHAMA CITY UNIVERSITY   (Japan)

^c KINKI UNIVERSITY   (Japan)

Author keywords

Alternative method; Eye irritation; MTT assay; Rabbit corneal epithelial cell; Rabbit corneal epithelium model

Indexed keywords

COLLAGEN GEL;

ANIMAL CELL; ARTICLE; CELL CULTURE; CELL VIABILITY; COMPARATIVE STUDY; CONTROLLED STUDY; CORNEA EPITHELIUM; DISEASE SEVERITY; EPITHELIUM CELL; EXPERIMENTAL MODEL; EYE IRRITATION; FEASIBILITY STUDY; IN VITRO STUDY; NONHUMAN; RABBIT; SENSITIVITY AND SPECIFICITY;

ANIMAL TESTING ALTERNATIVES; ANIMALS; CELLS, CULTURED; CORNEA; DOSE-RESPONSE RELATIONSHIP, DRUG; EPITHELIAL CELLS; IRRITANTS; MODELS, ANATOMIC; RABBITS;

EID: 70349451360     PISSN: 00316903     EISSN: 13475231     Source Type: Journal    
DOI: 10.1248/yakushi.129.1113     Document Type: Article

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