The biological information obtainable from circulating tumor cells

Breast

Volumn 18, Issue SUPPL.3, 2009, Pages

  Cristofanilli, Massimo ^a  

^a UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

Author keywords

Breast cancer; CTCs; HER 2; Prognosis; Stem cells

Indexed keywords

EPIDERMAL GROWTH FACTOR RECEPTOR 2; EPITHELIAL CELL ADHESION MOLECULE; TRASTUZUMAB;

ARTICLE; BREAST CANCER; CANCER ADJUVANT THERAPY; CANCER STEM CELL; CANCER SURVIVAL; CELL ASSAY; CIRCULATING TUMOR CELL; CYTOLOGY; DRUG RESPONSE; GENE AMPLIFICATION; GENE EXPRESSION; HUMAN; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROGNOSIS; TUMOR CELL;

EID: 70349449387     PISSN: 09609776     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-9776(09)70270-X     Document Type: Article

References (29)

1. http://cra.nci.nih.gov/3_types_cancer/breast_cancer.htm
2. Folkman J. Tumor angiogenesis: therapeutic implications. N Engl J Med 285 21 (1971) 1182-1186
3. Ashworth T. A case of cancer in which cells similar to those in the tumours were seen in the blood after death. Aust Med J 14 (1869) 146
4. Roberts S., Watne A., and McGrath R. Technique and results of isolation of cancer cells from the circulating blood. Am Med Assoc Arch Surg 76 (1958) 334-346
5. Long L., Jonasson O., Roberts S., McGrath R., McGrew E., and Cole W.H. Cancer cells in blood. Results of a simplified isolation technique. Arch Surg 80 (1960) 910-919
6. Dontu G., Al-Hajj M., Abdallah W.M., Clarke M.F., and Wicha M.S. Stem cells in normal breast development and breast cancer. Cell Prolif 36 Suppl 1 (2003) 59-72
7. Al-Hajj M., Wicha M.S., Benito-Hernandez A., Morrison S.J., and Clarke M.F. Prospective identification of tumorigenic breast cancer cells. Proc Natl Acad Sci USA 100 7 (2003) 3983-3988
8. Al-Hajj M., Becker M.W., Wicha M., Weissman I., and Clarke M.F. Therapeutic implications of cancer stem cells. Curr Opin Genet Dev 14 1 (2004) 43-47
9. Bossolasco P., Ricci C., Farina G., et al. Detection of micrometastatic cells in breast cancer by RT-pCR for the mammaglobin gene. Cancer Detect Prev 26 1 (2002) 60-63
10. Gross H.J., Verwer B., Houck D., Hoffman R.A., and Recktenwald D. Model study detecting breast cancer cells in peripheral blood mononuclear cells at frequencies as low as 10(-7). Proc Natl Acad Sci USA 92 2 (1995) 537-541
11. Martin K.J., Graner E., Li Y., et al. High-sensitivity array analysis of gene expression for the early detection of disseminated breast tumor cells in peripheral blood. Proc Natl Acad Sci USA 98 5 (2001) 2646-2651
12. Pachmann K., Heiss P., Demel U., and Tilz G. Detection and quantification of small numbers of circulating tumour cells in peripheral blood using laser scanning cytometer (LSC). Clin Chem Lab Med 39 9 (2001) 811-817
13. Racila E., Euhus D., Weiss A.J., et al. Detection and characterization of carcinoma cells in the blood. Proc Natl Acad Sci USA 95 8 (1998) 4589-4594
14. Witzig T.E., Bossy B., Kimlinger T., et al. Detection of circulating cytokeratin-positive cells in the blood of breast cancer patients using immunomagnetic enrichment and digital microscopy. Clin Cancer Res 8 5 (2002) 1085-1091
15. Kagan. A sample preparation and analysis system for identification of circulating tumor cells. J Clin Ligand Assay 25 1 (2002) 104-110 (7)
16. Terstappen L.W., Rao C., Gross S., and Weiss A.J. Peripheral blood tumor cell load reflects the clinical activity of the disease in patients with carcinoma of the breast. Int J Oncol 17 3 (2000) 573-578
17. Riethdorf S., Fritsche H., Muller V., et al. Detection of circulating tumor cells in peripheral blood of patients with metastatic breast cancer: a validation study of the CellSearch System. Clin Cancer Res 13 3 (2007) 920-928
18. Lankiewicz S., Gutierrez B., and B̈ocher O. Quantitative real-time RT-PCR of disseminated tumor cells in combination with immunomagnetic cell enrichment. Mol Biotechnol 34 (2006) 15-27
19. Austrup F., Uciechowski P., and Eder C. Prognostic value of genomic alterations in minimal residual cancer cells purified from the blood of breast cancer patients. Br J Cancer 83 (2001) 1664-1673
20. Meng S., Tripathy D., Shete S., et al. HER-2 gene amplification can be acquired as breast cancer progresses. Proc Natl Acad Sci USA 101 25 (2004) 9393-9398
21. Meng S., Tripathy D., Shete S., et al. uPAR and HER-2 gene status in individual breast cancer cells from blood and tissues. Proc Natl Acad Sci USA 103 46 (2006) 17361-17365
22. Cristofanilli M., Budd G.T., Ellis M.J., et al. Circulating tumor cells, disease progression, and survival in metastatic breast cancer. N Engl J Med 351 8 (2004) 781-791
23. Cristofanilli M., Hayes D.F., Budd G.T., et al. Circulating tumor cells: a novel prognostic factor for newly diagnosed metastatic breast cancer. J Clin Oncol 23 7 (2005) 1420-1430
24. Pierga J.Y., Bidard F.C., Mathiot C., et al. Circulating tumor cell detection predicts early metastatic relapse after neoadjuvant chemotherapy in large operable and locally advanced breast cancer in a phase II randomized trial. Clin Cancer Res 14 21 (2008) 7004-7010
25. Rack B., Schindlbeck C., Schneeweiss A., et al. Prognostic relevance of circulating tumor cells (CTCs) in peripheral blood of breast cancer patients before and after adjuvant chemotherapy: the German SUCCESS-Trial. Proc Am Soc Clin Oncol (2008) 26 [abstract 503].
26. Ignatiadis M., Kallergi G., Ntulia M., et al. Prognostic value of the molecular detection of circulating tumor cells using a multimarker reverse transcription-PCR assay for cytokeratin 19, mammaglobin A, and HER2 in early breast cancer. Clin Cancer Res 14 9 (2008) 2593-2600
27. Fehm T, Solomayer EF, Hoffmann O, et al. Comparison between circulating and disseminated tumor cells in breast cancer. Presented at the 31th San Antonio Breast Cancer Symposium, December 11-13, 2009 (abstract 301).
28. Tewes M., Aktas B., Welt A., et al. Molecular profiling and predictive value of circulating tumor cells in patients with metastatic breast cancer: an option for monitoring response to breast cancer related therapies. Breast Cancer Res Treat 115 3 (2009) 581-590
29. Reuben JM, Lee B-N, Li C., et al. Genomic of circulating tumor cells in metastatic breast cancer. Breast J 2009 (in press).