Substrate binding modifies the hinge bending characteristics of human 3-phosphoglycerate kinase: A molecular dynamics study

Proteins: Structure, Function and Bioinformatics

Volumn 77, Issue 2, 2009, Pages 319-329

  Palmai, Zoltan ^a,b   Chaloin, Laurent ^c   Lionne, Corinne ^c   Fidy, Judit ^a,b   Perahia, David ^d   Balog, Erika ^a  

^a SEMMELWEIS UNIVERSITY   (Hungary)

^b Research Group for Membrane Biology of HAS   (Hungary)

^c University of Montpellier I and II   (France)

^d INSTITUTE FOR INTEGRATIVE BIOLOGY OF THE CELL I2BC   (France)

Author keywords

Correlation of motions; Hinge bending; Human PGK; Molecular dynamics; Substrate binding

Indexed keywords

PHOSPHOGLYCERATE KINASE;

ARTICLE; HUMAN; MOLECULAR DYNAMICS; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN STRUCTURE;

BINDING SITES; COMPUTER SIMULATION; DIPHOSPHOGLYCERIC ACIDS; HUMANS; LIGANDS; MODELS, MOLECULAR; PHOSPHOGLYCERATE KINASE; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; THERMODYNAMICS;

EID: 70349448460     PISSN: 08873585     EISSN: 10970134     Source Type: Journal    
DOI: 10.1002/prot.22437     Document Type: Article

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