Posttranslational interference of Ty1 retrotransposition by antisense RNAs

Proceedings of the National Academy of Sciences of the United States of America

Volumn 106, Issue 37, 2009, Pages 15657-15662

  Matsuda, Emiko ^a   Garfinkel, David J ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

Author keywords

Retrotransposon; RNA interference; Saccharomyces; Virus like particles

Indexed keywords

COMPLEMENTARY DNA; COMPLEMENTARY RNA;

ARTICLE; CONTROLLED STUDY; GENE SEQUENCE; GENETIC TRANSCRIPTION; NONHUMAN; PRIORITY JOURNAL; RETROPOSON; RETROVIRUS; REVERSE TRANSCRIPTION; RNA TRANSLATION; SACCHAROMYCES; VIRUS PARTICLE; VIRUS REPLICATION;

GENE DOSAGE; GENES, FUNGAL; MODELS, GENETIC; PROTEIN PROCESSING, POST-TRANSLATIONAL; RETROELEMENTS; RNA INTERFERENCE; RNA, ANTISENSE; RNA, FUNGAL; SACCHAROMYCES; SACCHAROMYCES CEREVISIAE;

SACCHAROMYCES; SACCHAROMYCES CEREVISIAE;

EID: 70349446101     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0908305106     Document Type: Article

References (34)

1. Girard A, Hannon GJ (2008) Conserved themes in small-RNA-mediated transposon control. Trends Cell Biol 18:136-148.
2. Voytas DF, Boeke JD (2002) MobileDNAII, ed Craig NL, Craigie R, Gellert M, Lambowitz AM (ASM Press, Washington, DC), pp 631-662.
3. Bolton EC, Coombes C, Eby Y, Cardell M, Boeke JD (2005) Identification and characterization of critical cis-acting sequences within the yeast Ty1 retrotransposon. Rna 11:308-322. (Pubitemid 40270823)
4. Feng YX, Moore SP, Garfinkel DJ, Rein A (2000) The genomic RNA in Ty1 virus-like particles is dimeric. J Virol 74:10819-10821.
5. Wilhelm M, Wilhelm FX (2005) Role of integrase in reverse transcription of the Saccharomyces cerevisiae retrotransposon Ty1. Eukaryot Cell 4:1057-1065. (Pubitemid 40817465)
6. Wilhelm M, Wilhelm FX (2006) Cooperation between reverse transcriptase and integrase during reverse transcription and formation of the preintegrative complex of Ty1. Eukaryot Cell 5:1760-1769. (Pubitemid 44622602)
7. Wilhelm M, Boutabout M, Wilhelm FX (2000) Expression of an active form of recombinant Ty1 reverse transcriptase in Escherichia coli: A fusion protein containing the C-terminal region of the Ty1 integrase linked to the reverse transcriptase- RNase H domain exhibits polymerase and RNase H activities. Biochem J 348:337-342. (Pubitemid 30345206)
8. Elder RT, Loh EY, Davis RW (1983) RNA from the yeast transposable element Ty1 has both ends in the direct repeats, a structure similar to retrovirus RNA. Proc Natl Acad Sci USA 80:2432-2436.
9. Curcio MJ, Garfinkel DJ (1991) Single-step selection for Ty1 element retrotransposition. Proc Natl Acad Sci USA 88:936-940.
10. Curcio MJ, Garfinkel DJ (1994) Heterogeneous functional Ty1 elements are abundant in the Saccharomyces cerevisiae genome. Genetics 136:1245-1259.
11. Curcio MJ, Garfinkel DJ (1992) Posttranslational control of Ty1 retrotransposition occurs at the level of protein processing. Mol Cell Biol 12:2813-2825.
12. Garfinkel DJ, Boeke JD, Fink GR (1985) Ty element transposition: Reverse transcriptase and virus-like particles. Cell 42:507-517.
13. Boeke JD, Garfinkel DJ, Styles CA, Fink GR (1985) Ty elements transpose through an RNA intermediate. Cell 40:491-500.
14. Moore SP, et al. (2004) Analysis of a Ty1-less variant of Saccharomyces paradoxus: The gain and loss of Ty1 elements. Yeast 21:649-660.
15. Garfinkel DJ, Nyswaner K, Wang J, Cho JY (2003) Post-transcriptional cosuppression of Ty1 retrotransposition. Genetics 165:83-99.
16. Velculescu VE, et al. (1997) Characterization of the yeast transcriptome. Cell 88:243-251.
17. NagalakshmiU, et al. (2008) The transcriptional landscape of the yeastgenomedefined by RNA sequencing. Science 320:1344-1349.
18. Hongay CF, Grisafi PL, Galitski T, Fink GR (2006) Antisense transcription controls cell fate in Saccharomyces cerevisiae. Cell 127:735-745. (Pubitemid 44716254)
19. Martens JA, Laprade L, Winston F (2004) Intergenic transcription is required to repress the Saccharomyces cerevisiae SER3 gene. Nature 429:571-574. (Pubitemid 38737662)
20. Berretta J, Pinskaya M, Morillon A (2008)Acryptic unstable transcript mediates transcriptional trans-silencing of the Ty1 retrotransposon in S. cerevisiae. Genes Dev 22:615-626. (Pubitemid 351342434)
21. Winston F, Durbin KJ, FinkGR(1984) The SPT3 gene is required for normal transcription of Ty elements in S. cerevisiae. Cell 39:675-682.
22. Kim JM, Vanguri S, Boeke JD, Gabriel A, Voytas DF (1998) Transposable elements and genome organization: A comprehensive survey of retrotransposons revealed by the complete Saccharomyces cerevisiae genome sequence. Genome Res 8:464-478. (Pubitemid 28256796)
23. Morillon A, Benard L, Springer M, Lesage P (2002) Differential effects of chromatin and Gcn4 on the 50-fold range of expression among individual yeast Ty1 retrotransposons. Mol Cell Biol 22:2078-2088. (Pubitemid 34224616)
24. Promislow DE, Jordan IK, McDonald JF (1999) Genomic demography: A life-history analysis of transposable element evolution. Proc Biol Sci 266:1555-1560.
25. Boeke JD, Styles CA, Fink GR (1986) Saccharomyces cerevisiae SPT3 gene is required for transposition and transpositional recombination of chromosomal Ty elements. Mol Cell Biol 6:3575-3581.
26. Maxwell PH, et al. (2004) Ty1 mobilizes subtelomeric Y' elements in telomerasenegative Saccharomyces cerevisiae survivors. Mol Cell Biol 24:9887-9898.
27. Lawler JF, Jr, Merkulov GV, Boeke JD (2002) A nucleocapsid functionality contained within the amino terminus of the Ty1 protease that is distinct and separable from proteolytic activity. J Virol 76:346-354.
28. Youngren SD, Boeke JD, Sanders NJ, Garfinkel DJ (1988) Functional organization of the retrotransposon Ty from Saccharomyces cerevisiae: Ty protease is required for transposition. Mol Cell Biol 8:1421-1431.
29. Cristofari G, Bampi C, Wilhelm M, Wilhelm FX, Darlix JL (2002) A 5′-3′ long-range interaction in Ty1 RNA controls its reverse transcription and retrotransposition. EMBO J 21:4368-4379. (Pubitemid 34898188)
30. Conte D, Jr, Barber E, Banerjee M, Garfinkel DJ, Curcio MJ (1998) Posttranslational regulation of Ty1 retrotransposition by mitogen-activated protein kinase Fus3. Mol Cell Biol 18:2502-2513. (Pubitemid 28183420)
31. Guthrie C, Fink GR (1991) Guide to Yeast Genetics and Molecular Biology (Academic, San Diego, CA).
32. Eichinger DJ, Boeke JD (1988) TheDNAintermediate in yeast Ty1 element transposition copurifies with virus-like particles: Cell-free Ty1 transposition. Cell 54:955-966.
33. Garfinkel DJ, Hedge AM, Youngren SD, Copeland TD (1991) Proteolytic processing of pol-TYB proteins from the yeast retrotransposon Ty1. J Virol 65:4573-4581.
34. Nyswaner KM, Checkley MA, Yi M, Stephens RM, Garfinkel DJ (2008) Chromatinassociated genes protect the yeast genome from Ty1 insertional mutagenesis. Genetics 178:197-214.