Development and validation of a reversed-phase HPLC method for quantitative determination of ginsenosides Rb1, Rd, F2, and compound K during the process of biotransformation of ginsenoside Rb1

Journal of Separation Science

Volumn 31, Issue 6-7, 2008, Pages 921-925

  Zhou, Wei ^a   Li, Jiyang ^a   Li, Xinwei ^a   Yan, Qin ^a   Zhou, Pei ^a  

^a FUDAN UNIVERSITY   (China)

Author keywords

Biotransformation; Ginsenoside; Gradient elution; Panax ginseng; Reversed phase

Indexed keywords

BIOCONVERSION; FERMENTATION; PLANTS (BOTANY); SEPARATION;

BIOTRANSFORMATION; GINSENOSIDE; GRADIENT ELUTION;

HIGH PERFORMANCE LIQUID CHROMATOGRAPHY;

20 O BETA DEXTRO GLUCOPYRANOSYL 20 PROTOPANAXADIOL; GINSENOSIDE; GINSENOSIDE F2; GINSENOSIDE RB 1; GINSENOSIDE RD;

ACCURACY; ARTICLE; BIOTRANSFORMATION; CHEMICAL ANALYSIS; CHEMICAL STRUCTURE; CORRELATION COEFFICIENT; FERMENTATION; LINEAR REGRESSION ANALYSIS; NONHUMAN; PAECILOMYCES; PAECILOMYCES BAINIER; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; SENSITIVITY ANALYSIS; SEPARATION TECHNIQUE;

CALIBRATION; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; FERMENTATION; GINSENOSIDES; HYDROPHOBICITY; MOLECULAR STRUCTURE;

PANAX GINSENG;

EID: 43249111542     PISSN: 16159306     EISSN: 16159314     Source Type: Journal    
DOI: 10.1002/jssc.200700406     Document Type: Article

References (21)

1. Yahara, S., Kaji, K., Tanaka, O., Chem. Pharm. Bull. 1979, 27, 99-92.
2. Ma, W. G., Mizutani, M., Malterud, K. E., Lu, S. L., Ducrey, B., Tahara, S., Phytochemistry 1999, 52, 1133-1139.
3. Kasai, R., Besso, H., Tanaka, O., Saruwatari, Y. I., Fuwa, T., Chem. Pharm. Bull. 1983, 31, 2120-2125.
4. Karikura, M., Miyase, T., Tanizawa, H., Takino, Y., Chem. Pharm. Bull. 1990, 38, 2859-2861.
5. Akao, T., Kida, H., Kanaoka, M., Hattori, M., Kobashi, K., J. Pharm. Pharmacol. 1998, 50, 1155-1160.
6. Bae, E. A., Choo, M. K., Park, E. K., Park, S. Y., Shin, H. Y., Kim, D. H., Biol. Pharm. Bull. 2002, 25, 743-747.
7. Lee, B. H., Lee, S. J., Hur, J. H., Lee, S., Sung, J. H., Huh, J. D., Moon, C. K., Planta Med. 1998, 64, 500-503.
8. Hasegawa, H., Uchiyama, M., Planta Med. 1998, 64, 696-700.
9. Wakabayashi, C., Murakami, K., Hasegawa, H., Murata, J., Saiki, L., Biochem. Biophys. Res. Commun. 1998, 246, 725-730.
10. Lee, H. U., Bae, E. A., Han, M. J., Kim, D. H., Liver. Int. 2005, 25, 1069-1073.
11. Park, E. K., Shin, Y. W., Lee, H. U., Kim, S. S., Lee, Y. C., Lee, B. Y., Kim, D. H., Biol. Pharm. Bull. 2005, 28, 652-656.
12. Hasegawa, H., Sung, J. H., Benno, Y., Planta Med. 1997, 63, 436-440.
13. Bae, E. A., Kim, N.Y., Han, M. J., Cho, M. K., Kim, D. H., J. Microbiol. Biotechnol. 2003, 13, 9-14.
14. Ma, J. S., Zhou, Q. L., Fei, X. F., Sun, Y., Wang, B. X., Acta Pharm. Sin. 2001, 36, 603-605.
15. Jiang, B. H., Han, Y., Zhao, Y. Q., Hu, X. M., Zheng, L. X., Chin. Tradit. Herb. Drugs. 2004, 35, 986-988.
16. Kim, S. K., Kang, B. Y., Cho, S. Y., Sung, D. S., Chang, H. K., Yeom, M. H., Kim, D. H., Sim, Y. C., Lee, Y. S., Biochem. Biophys. Res. Commun. 2004, 316, 348-355.
17. Ma, Y. C., Luo, M., Lynn, M., Monique, D., Chin. J. Med. Chem. 1996, 6, 11-20.
18. Zhai, W. M., Yuan, Y. S., Zhou, Y. X., Wei, L. X., Chin. J. Chin. Mater. Med. 2001, 26, 481-482.
19. Jian, B. W., Li, S. P., Chen, J. M., Wang, Y. T., J. Sep. Sci. 2007, 30, 825-832.
20. Zhou, W., Luo, Z. S., Zhou, P., Chin, J. Chromatogr. 2005, 23, 270-272.
21. Zhou, W., Feng, M. Q., Li, J. Y., Zhou, P., J. Asian Nat. Prod. Res. 2006, 8, 519-527.