The effects of intra-operative amiodarone loading on the systemic inflammatory response syndrome induced by cardiopulmonary bypass

Anadolu Kardiyoloji Dergisi

Volumn 9, Issue 4, 2009, Pages 318-324

  Rahman, Ali ^a   Akbulut, Handan ^a   Bayar, Mustafa Kemal ^a   Özdan, Mehmet ^a   Burma, Oktay ^a   Uysal, Ayhan ^a  

^a FIRAT UNIVERSITY   (Turkey)

Author keywords

Amiodarone; C reactive protein; Cardiopulmonary bypass; Coronary artery surgery; Inflammatory response; Interleukin

Indexed keywords

AMIODARONE; C REACTIVE PROTEIN; CORDARONE IV; INTERLEUKIN 10; INTERLEUKIN 6; UNCLASSIFIED DRUG;

ADULT; AGED; ANESTHESIA INDUCTION; ARTICLE; ARTIFICIAL VENTILATION; CARDIOPULMONARY BYPASS; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; DRUG MECHANISM; FEMALE; HEART ATRIUM FIBRILLATION; HEART INDEX; HEART RATE; HUMAN; INTENSIVE CARE UNIT; LOADING DRUG DOSE; LUNG ARTERY PRESSURE; MALE; MEAN ARTERIAL PRESSURE; PROTEIN BLOOD LEVEL; PROTEIN SYNTHESIS INHIBITION; PULMONARY ARTERY OCCLUSION PRESSURE; RANDOMIZED CONTROLLED TRIAL; SYSTEMIC INFLAMMATORY RESPONSE SYNDROME;

AGED; AMIODARONE; ANTI-ARRHYTHMIA AGENTS; BIOLOGICAL MARKERS; C-REACTIVE PROTEIN; CARDIOPULMONARY BYPASS; CYTOKINES; FEMALE; HUMANS; INFLAMMATION MEDIATORS; INTERLEUKIN-10; INTERLEUKIN-6; INTRAOPERATIVE CARE; MALE; MIDDLE AGED; SYSTEMIC INFLAMMATORY RESPONSE SYNDROME;

EID: 70349392793     PISSN: 13028723     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (25)

1. Levy JH, Tanaka KA. Inflammatory response to cardiopulmonary bypass. Ann Thorac Surg 2003; 75: S715-20.
2. Paparella D, Yau TM, Young E. Cardiopulmonary bypass induced inflammation: pathophysiology and treatment. An update. Eur Cardiothoracic Surg 2002; 21: 232-44.
3. Bourbon A, Vionnet M, Leprince P, Vaissier J, Copelend J, McDonagh P, et al. The effect of methylprednisolone treatment on the cardiopulmonary bypass-induced systemic inflammatory response. Eur J Cardiothorac Surg 2004; 21: 932-8.
4. Giomarelli P, Scolletta S, Borrelli E, Biagioli B. Myocardial and lung injury after cardiopulmonary bypass: role of interleukin (IL)-10. Ann Thorac Surg 2003; 76: 117-23.
5. Krakauer T. IL-10 inhibits the adhesion of leukocytic cells to IL-1 activated human endothelial cells. Immunol Lett 1995; 45: 61-5.
6. Wu ZK, Pehkonen E, Laurikka J, Kaukinen L, Honkonen EL, Kaukinen S, et al. Myocardial lactate production is not involved in the ischemic preconditioning mechanism in coronary artery bypass graft surgery patients. J Cardiothorac Vasc Anesth 2001; 15: 412-7.
7. Akins CW, Boucher CA, Pohost GM. Preservation of interventricular septal function in patients having coronary artery bypass grafts without cardiopulmonary bypass. Am Heart J 1984; 107: 304-9.
8. DiDomenico RJ, Massad MG. Pharmacologic strategies for prevention of atrial fibrillation after open heart surgery. Ann Thorac Surg 2005; 79: 728-40.
9. Matsumori A, Ono K, Nishio R, Nose Y, Sasayama S. Amiodarone inhibits production of tumor necrosis factor-α by human mononuclear cells. Circulation 1997; 96: 1386-9.
10. Karpel JP, Mitsudo S, Norin A. Natural kiler cell activity in a rat model of amiodarone-induced interstitial lung disease. Chest 1991; 99: 230-4.
11. Karth GD, Buberl A, Nikfardjam M, Meyer B, Wollenek G, Grimm M, et al. Role of amiodarone on the systemic inflammatory response induced by cardiac surgery: proinflammatory actions. Can J Anesth 2007; 54: 262-8.
12. Nieman G, Searles B, Carney D, Mccann U, Schiller H, Lutz C. Systemic inflammation induced by cardiopulmonary bypass: a review of pathogenesis and treatment. J Extra Corpor Technol 1999; 31: 202-10.
13. Sawa Y, Ichikawa H, Kagisaki K, Ohata T, Matsuda H. Interleukin-6 derived from hypoxic myocytes promotes neutrophil-mediated reperfusion injury in myocardium. J Thorac Cardiovasc Surg 1998; 116: 511-7.
14. Biancari F, Lahtinen J, Lepojarvi S, Rainio P, Salmella E, Pokela R. Preoperative C reactive protein and outcome after coronary artery bypass surgery. Ann Thorac Surg 2003; 76: 2007-12.
15. Santamaria DB, Campbell DJ. Plasminogen activator inhibitor activity is associated with raised lactate levels after cardiac surgery with cardiopulmonary bypass. Crit Care Med 2003; 31: 1053-9.
16. Türköz A, Çiǧli A, But K, Sezgin N, Türköz R, Gülcan Ö, et al. The effects of aprotinin and steroids on generation of cytokines during coronary artery surgery. J Cardiothorac Vasc Anesth 2001; 15: 603-10.
17. Pepys MB, Hirschfield GM. C-reactive protein: a critical update. J Clin Invest 2003; 111: 1805-12.
18. Demers P, Elkouri S, Martineau R, Couturier A, Cartier R. Outcome with high blood lactate levels during cardiopulmonary bypass in adult cardiac operation. Ann Thorac Surg 2000; 70: 2082-6.
19. The American Heart Association in collaboration with the International Liaison Committee on Resuscitation (ILCOR). Advanced cardiovascular life support: Section 5: Pharmacology I: Agents for arrhythmias. Circulation 2000;102 (8suppl): I 112-8.
20. Singh SN, Fletcher RD, Fisher SG, Singh BN, Lewis HD, Deedwania PC, et al. Amiodarone in patients with congestive heart failure and asymptomatic ventricular arrhythmia: survival trial of antiarrhythmic therapy in congestive heart failure. N Engl J Med 1995; 333: 77-82.
21. Ito H, Ono K, Nishio R, Sasayama S, Matsumori A. Amiodarone inhibits interleukin 6 production and attenuates myocardial injury induced by viral myocarditis in mice. Cytokine 2002; 17: 197-202.
22. Finkel MS, Oddis CV, Jacob TD, Watkins SC, Hattler BG, Simmons RL. Negative inotropic effects of cytokines on the heart mediated by nitric oxide. Science 1992; 257: 387-9.
23. Futamura Y. Effects of amiodarone on cytokine release and on enzyme activities of Mouse alveolar macrophages, bone marrow macrophages and blood monocytes. J Toxicol Sci 1996; 21: 125-34.
24. Oral H, Fisher SG, Fay WP, Singh SN, Fletcher RD, Morady F. Effects of amiodarone on tumor necrosis factor-α levels in congestive heart failure secondary to ischemic or idiopathic dilated cardiomyopathy. Am J Cardiol 1999; 83: 388-91.
25. Ascrafian H, Davey P. Is Amiodarone an underrecognized cause of acute respiratory failure in the ICU? Chest 2001; 120: 275-82.