Glutathione redox status in mitochondria and cytoplasm differentially and sequentially activates apoptosis cascade in dopamine-melanin-treated SH-SY5Y cells

Neuroscience Letters

Volumn 465, Issue 2, 2009, Pages 118-122

  Naoi, Makoto ^a   Yi, Hong ^a   Maruyama, Wakako ^b   Inaba, Keiko ^a   Shamoto Nagai, Masayo ^b   Akao, Yukihiro ^a   Gerlach, Manfred ^c   Riederer, Peter ^c  

^a GIFU INTERNATIONAL INSTITUTE OF BIOTECHNOLOGY   (Japan)

^b NATIONAL CENTER FOR GERIATRICS AND GERONTOLOGY   (Japan)

^c Clinical Neurochemistry   (Germany)

Author keywords

Apoptosis; Caspases; GSH; Melanin; Mitochondria; Parkinson's disease

Indexed keywords

ACETYLCYSTEINE; CASPASE 3; CYSTEINYL DOPAMINE MELANIN; CYTOCHROME C; DITHIOTHREITOL; DOPAMINE; DOPAMINE MELANIN; GLUTATHIONE; MELANIN; NEUROMELANIN; PIGMENT; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE (UBIQUINONE); THIOL DERIVATIVE; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CONTROLLED STUDY; CYTOPLASM; CYTOTOXICITY; DOPAMINERGIC NERVE CELL; ENZYME ACTIVATION; ENZYME RELEASE; HUMAN; HUMAN CELL; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOCHONDRIAL PERMEABILITY; MITOCHONDRION; NERVE DEGENERATION; NEUROBLASTOMA CELL; OXIDATION; OXIDATION REDUCTION STATE; OXIDATIVE STRESS; PARKINSON DISEASE; PRIORITY JOURNAL; PROTEIN MODIFICATION; SIGNAL TRANSDUCTION;

APOPTOSIS; CASPASE 3; CELL LINE, TUMOR; CYTOCHROMES C; CYTOPLASM; DOPAMINE; GLUTATHIONE; HUMANS; MELANINS; MEMBRANE POTENTIAL, MITOCHONDRIAL; MITOCHONDRIA; OXIDATION-REDUCTION; SIGNAL TRANSDUCTION; SULFHYDRYL COMPOUNDS; TIME FACTORS;

EID: 70349329227     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neulet.2009.08.082     Document Type: Article

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