Comparison of degranulation of easily mobilizable intracellular granules by human phagocytes in healthy subjects and patients with infectious diseases

Human Immunology

Volumn 70, Issue 10, 2009, Pages 813-819

  Nuutila, Jari ^a   Jalava Karvinen, Päivi ^b   Hohenthal, Ulla ^b   Laitinen, Iina ^a   Kotilainen, Pirkko ^b   Rajamäki, Allan ^b   Nikoskelainen, Jukka ^b   Lilius, Esa Matti ^a  

^a UNIVERSITY OF TURKU   (Finland)

^b TURKU UNIVERSITY HOSPITAL   (Finland)

Author keywords

Bacterial infection; CD11b; CD35; Degranulation; Monocyte; Neutrophil; Viral infection

Indexed keywords

ANTIBIOTIC AGENT; ANTIVIRUS AGENT; CALCIUM; CD11B ANTIGEN; CEPHALOSPORIN; COMPLEMENT COMPONENT C3B RECEPTOR; MONOCLONAL ANTIBODY;

ADULT; ARTICLE; BACTERIAL INFECTION; CALCIUM CELL LEVEL; CELL ACTIVATION; CELL GRANULE; CELL ISOLATION; COMPLEMENT ACTIVATION; CONTROLLED STUDY; DEGRANULATION; DNA VIRUS; EOSINOPHIL; FEMALE; FEVER; FLOW CYTOMETRY; GRAM NEGATIVE BACTERIUM; GRAM POSITIVE BACTERIUM; HUMAN; HUMAN CELL; IMMUNOPHENOTYPING; MAJOR CLINICAL STUDY; MALE; MICROBIOLOGICAL EXAMINATION; MONOCYTE; NEUTROPHIL; PHAGOCYTE; PRIORITY JOURNAL; RNA VIRUS; SECRETORY VESICLE; STREPTOCOCCUS PNEUMONIAE; VIRUS INFECTION;

ADULT; AGED; ANTIGENS, CD11B; CELL DEGRANULATION; CYTOPLASMIC GRANULES; EOSINOPHILS; FEMALE; HUMANS; INFECTION; MALE; MIDDLE AGED; MONOCYTES; NEUTROPHILS; PHAGOCYTOSIS; RECEPTORS, COMPLEMENT 3B; SECRETORY VESICLES; UP-REGULATION;

EID: 70349325851     PISSN: 01988859     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.humimm.2009.06.017     Document Type: Article

References (38)

1. Elghetany M.T. Surface antigen changes during normal neutrophilic development: a critical review. Blood Cells Mol Dis 28 (2002) 260-274
2. Sengelov H., Kjeldsen L., Kroeze W., Berger M., and Borregaard N. Secretory vesicles are the intracellular reservoir of complement receptor 1 in human neutrophils. J Immunol 153 (1994) 804-810
3. Calafat J., Kuijpers T.W., Janssen H., Borregaard N., Verhoeven A.J., and Roos D. Evidence for small intracellular vesicles in human blood phagocytes containing cytochrome b558 and the adhesion molecule CD11b/CD18. Blood 81 (1993) 3122-3129
4. Faurschou M., and Borregaard N. Neutrophil granules and secretory vesicles in inflammation. Microbes Infect 5 (2003) 1317-1327
5. Gullberg U., Bengtsson N., Bulow E., Garwicz D., Lindmark A., and Olsson I. Processing and targeting of granule proteins in human neutrophils. J Immunol Methods 232 (1999) 201-210
6. Etzioni A. Adhesion molecules-their role in health and disease. Pediatr Res 39 (1996) 191-198
7. Shalekoff S., Page-Shipp L., and Tiemessen C.T. Effects of anticoagulants and temperature on expression of activation markers CD11b and HLA-DR on human leukocytes. Clin Diagn Lab Immunol 5 (1998) 695-702
8. Lundahl J., Hallden G., Hallgren M., Skold C.M., and Hed J. Altered expression of CD11b/CD18 and CD62L on human monocytes after cell preparation procedures. J Immunol Methods 180 (1995) 93-100
9. Labrouche S., Freyburger G., Belloc F., and Boisseau M.R. Influence of selected heparins on human neutrophil functions in vitro. Thromb Haemost 68 (1992) 556-562
10. Krych M., Hauhart R., and Atkinson J.P. Structure-function analysis of the active sites of complement receptor type 1. J Biol Chem 273 (1998) 8623-8629
11. Tas S.W., Klickstein L.B., Barbashov S.F., and Nicholson-Weller A. C1q and C4b bind simultaneously to CR1 and additively support erythrocyte adhesion. J Immunol 163 (1999) 5056-5063
12. Ueda T., Rieu P., Brayer J., and Arnaout M.A. Identification of the complement iC3b binding site in the beta 2 integrin CR3 (CD11b/CD18). Proc Natl Acad Sci USA 91 (1994) 10680-10684
13. van de Winkel J.G., and Capel P.J. Human IgG Fc receptor heterogeneity: molecular aspects and clinical implications. Immunol Today 14 (1993) 215-221
14. Zhou M.J., and Brown E.J. CR3 (Mac-1, alpha M beta 2, CD11b/CD18) and Fc gamma RIII cooperate in generation of a neutrophil respiratory burst: requirement for Fc gamma RIII and tyrosine phosphorylation. J Cell Biol 125 (1994) 1407-1416
15. Worth R.G., Mayo-Bond L., van de Winkel J.G., Todd III R.F., and Petty H.R. CR3 (alphaM beta2; CD11b/CD18) restores IgG-dependent phagocytosis in transfectants expressing a phagocytosis-defective Fc gammaRIIA (CD32) tail-minus mutant. J Immunol 157 (1996) 5660-5665
16. Nuutila J., Hohenthal U., Laitinen I., Kotilainen P., Rajamaki A., Nikoskelainen J., et al. Quantitative analysis of complement receptors, CR1 (CD35) and CR3 (CD11b), on neutrophils improves distinction between bacterial and viral infections in febrile patients: comparison with standard clinical laboratory data. J Immunol Methods 315 (2006) 191-201
17. Hohenthal U., Nuutila J., Lilius E.M., Laitinen I., Nikoskelainen J., and Kotilainen P. Measurement of complement receptor 1 on neutrophils in bacterial and viral pneumonia. BMC Infect Dis 6 (2006) 11
18. Nuutila J., Hohenthal U., Laitinen I., Kotilainen P., Rajamaki A., Nikoskelainen J., et al. Simultaneous quantitative analysis of FcgammaRI (CD64) expression on neutrophils and monocytes: a new, improved way to detect infections. J Immunol Methods 328 (2007) 189-200
19. de Grooth B.G., Terstappen L.W., Puppels G.J., and Greve J. Light-scattering polarization measurements as a new parameter in flow cytometry. Cytometry 8 (1987) 539-544
20. Berger M., Birx D.L., Wetzler E.M., O'Shea J.J., Brown E.J., and Cross A.S. Calcium requirements for increased complement receptor expression during neutrophil activation. J Immunol 135 (1985) 1342-1348
21. Svanborg C., Godaly G., and Hedlund M. Cytokine responses during mucosal infections: role in disease pathogenesis and host defence. Curr Opin Microbiol 2 (1999) 99-105
22. Hallett M.B., and Lloyds D. Neutrophil priming: the cellular signals that say "amber" but not "green.". Immunol Today 16 (1995) 264-268
23. Korchak H.M., Rutherford L.E., and Weissmann G. Stimulus response coupling in the human neutrophil. I. Kinetic analysis of changes in calcium permeability. J Biol Chem 259 (1984) 4070-4075
24. Lew P.D., Monod A., Waldvogel F.A., Dewald B., Baggiolini M., and Pozzan T. Quantitative analysis of the cytosolic free calcium dependency of exocytosis from three subcellular compartments in intact human neutrophils. J Cell Biol 102 (1986) 2197-2204
25. Wheeler E.S., and Weiss G.B. Correlation between response to norepinephrine and removal of 45Ca from high-affinity binding sites by extracellular EDTA in rabbit aortic smooth muscle. J Pharmacol Exp Ther 211 (1979) 353-359
26. Jack R.M., and Fearon D.T. Selective synthesis of mRNA and proteins by human peripheral blood neutrophils. J Immunol 140 (1988) 4286-4293
27. Neuman E., Huleatt J.W., and Jack R.M. Granulocyte-macrophage colony-stimulating factor increases synthesis and expression of CR1 and CR3 by human peripheral blood neutrophils. J Immunol 145 (1990) 3325-3332
28. Shi C., and Simon D.I. Integrin signals, transcription factors, and monocyte differentiation. Trends Cardiovasc Med 16 (2006) 146-152
29. Strauss-Ayali D., Conrad S.M., and Mosser D.M. Monocyte subpopulations and their differentiation patterns during infection. J Leukocyte Biol 82 (2007) 244-252
30. Luscinskas F.W., Kansas G.S., Ding H., Pizcueta P., Schleiffenbaum B.E., Tedder T.F., et al. Monocyte rolling, arrest and spreading on IL-4-activated vascular endothelium under flow is mediated via sequential action of L-selectin, beta 1-integrins, and beta 2-integrins. J Cell Biol 125 (1994) 1417-1427
31. Zhang L., Yoshimura T., and Graves D.T. Antibody to Mac-1 or monocyte chemoattractant protein-1 inhibits monocyte recruitment and promotes tumor growth. J Immunol 158 (1997) 4855-4861
32. Gallin J.I., and Snyderman R. Inflammation: basic principles and clinical correlates (1999), Lippincott Williams & Wilkins, Philadelphia, PA pp. 721-68
33. Pettersen C.A., and Adler K.B. Airways inflammation and COPD: epithelial-neutrophil interactions. Chest 121 (2002) 142S-150S
34. Colamussi M.L., White M.R., Crouch E., and Hartshorn K.L. Influenza A virus accelerates neutrophil apoptosis and markedly potentiates apoptotic effects of bacteria. Blood 93 (1999) 2395-2403
35. Engelich G., White M., and Hartshorn K.L. Neutrophil survival is markedly reduced by incubation with influenza virus and Streptococcus pneumoniae: role of respiratory burst. J Leukocyte Biol 69 (2001) 50-56
36. Ajroud K., Sugimori T., Goldmann W.H., Fathallah D.M., Xiong J.P., and Arnaout M.A. Binding affinity of metal ions to the CD11b A-domain is regulated by integrin activation and ligands. J Biol Chem 279 (2004) 25483-25488
37. Lee J.O., Rieu P., Arnaout M.A., and Liddington R. Crystal structure of the A domain from the alpha subunit of integrin CR3 (CD11b/CD18). Cell 80 (1995) 631-638
38. Oxvig C., and Springer T.A. Experimental support for a beta-propeller domain in integrin alpha-subunits and a calcium binding site on its lower surface. Proc Natl Acad Sci USA 95 (1998) 4870-4875