Investigation of the HPLC response of NSAIDs by fractional experimental design and multivariate regression analysis. Response optimization and new retention parameters

Journal of Pharmaceutical and Biomedical Analysis

Volumn 51, Issue 1, 2010, Pages 46-55

  Iuliani, Piera ^a   Carlucci, Giuseppe ^a   Marrone, Alessandro ^a  

^a UNIVERSITY OF CHIETI   (Italy)

Author keywords

Experimental design; MLR analysis; Response optimization; Retention parameters; RP HPLC

Indexed keywords

FENBUFEN; FLURBIPROFEN; FURAPROFEN; IBUPROFEN; INDOMETACIN; INDOPROFEN; KETOPROFEN; NONSTEROID ANTIINFLAMMATORY AGENT;

ACCURACY; ARTICLE; CHEMOMETRIC ANALYSIS; CONTROLLED STUDY; MULTIVARIATE LOGISTIC REGRESSION ANALYSIS; PREDICTION; PRIORITY JOURNAL; PROCESS OPTIMIZATION; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY;

ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; CHEMISTRY, PHARMACEUTICAL; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; MODELS, CHEMICAL; MOLECULAR STRUCTURE; MULTIVARIATE ANALYSIS; REGRESSION ANALYSIS;

EID: 70349319344     PISSN: 07317085     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jpba.2009.08.001     Document Type: Article

References (24)

1. Dorsey J.G., Cooper W.T., Siles B.A., Foley J.P., and Barth H.G. Liquid chromatography: theory and methodology. Anal. Chem. 68 (1996) 515-568
2. Kaliszan R. QSSR: quantitative structure-(chromatographic) retention relationships. Chem. Rev. 107 (2007) 3212-3246
3. Platts J.A., Abraham M.H., Butina D., and Hersey A. Estimation of molecular linear free energy relationship by a group contribution approach. J. Chem. Inf. Comput. Sci. 39 (1999) 835-845
4. Platts J.A., Abraham M.H., Butina D., and Hersey A. Estimation of molecular linear free energy relationship by a group contribution approach. 2. Prediction of partition coefficients. J. Chem. Inf. Comput. Sci. 40 (2000) 71-80
5. Baczek T., and Kaliszan R. Combination of linear solvent strength model and quantitative structure-retention relationships as a comprehensive procedure of approximate prediction of retention in gradient liquid chromatography. J. Chromatogr. A 962 (2002) 41-55
6. Kaliszan R. Quantitative structure-retention relationships applied to reversed-phase high-performance liquid chromatography. J. Chromatogr. A 656 (1993) 417-435
7. Kaliszan R., Van Straten M.A., Markuszewski M., Crames C.A., and Claessens H.A. Molecular mechanism of retention in reversed-phase high-performance liquid chromatography and classification of modern stationary phases by using quantitative structure-retention relationships. J. Chromatogr. A 855 (1999) 455-486
8. Kantoci D. A study of an empirical equation for the evaluation of separation efficiency in chromatography. J. Liq. Chromatogr. Relat. Technol. 19 (1996) 853-866
9. Bylund D., Bergens A., and Jacobsson S.P. Optimization of chromatographic separations by use of a chromatographic response function, empirical modeling, and multivariate analysis. Chromatographia 44 (1997) 74-80
10. Guillaume Y., Cavalli E.J., Peyrin E., and Guinchard C. A new approach to study benzodiazepine separation and the differences between a methanol/water and acetonitrile/water mixture on column efficiency in liquid chromatography. J. Liq. Chromatogr. Relat. Technol. 20 (1997) 1741-1756
11. Dorsey J.G., Cooper W.T., Siles B.A., Foley J.P., and Barth H.G. Liquid chromatography: theory and methodology. Anal. Chem. 70 (1998) 591-644
12. Ong T.H., Wong Y.S., Woo S.O., and Ng S. Factorial designs for optimization in high-performance liquid chromatography of pharmaceuticals. Bull. Singapore Natl. Inst. Chem. 22 (1994) 19-29
13. Kaufmann P. Multivariate optimisation strategy for liquid chromatography. II. Exploring and finding optimal conditions in the search area of the multidimensional solvent space. Chemom. Intell. Lab. Syst. 27 (1995) 105-114
14. Preu M., Guyot D., and Petza M. Development of a gas chromatography-mass spectrometry method for the analysis of aminoglicoside antibiotics using experimental design for the optimization of the derivatization reactions. J. Chromatogr. A 818 (1998) 95-108
15. Brereton R.G. Chemometrics-data Analysis for the Laboratory and Chemical Plant (2002), John Wiley & Sons Ltd., Chirchester, England pp. 76-77
16. Lan W.G., Chee K.K., Wong M.K., Lee H.K., and Sin Y.M. Orthogonal array design as a chemometric method for the optimization of analytical procedures. Part 5. Three-level design and its application in microwave dissolution of biological samples. Analyst 120 (1995) 281-287
17. Wan H.B., Lan W.G., Wong M.K., and Mok C.Y. Orthogonal array designs for the optimization of liquid chromatographic analysis of pesticides. Anal. Chim. Acta 289 (1994) 371-380
18. Andersson A.M., Karlsson A., Josefson M., and Gottfries J. Evaluation of mobile phase additives in LC-systems using chemometrics. Chromatographia 38 (1994) 715-722
19. Guillaume Y., and Guinchard C. A new method to study column efficiency and the separation of seven compounds in reversed-phase chromatography. J. Chromatogr. Sci. 33 (1995) 204-210
20. Marengo E., Gennaro M.C., Gianotti V., and Prenesti E. Optimization of the separation of mono- and dichloroanilines in ion interaction high-performance liquid chromatography. J. Chromatogr. A 863 (1999) 1-11
21. Baranda A.B., Berasaluce O., Jiménez R.M., and Alonso R.M. LC-DAD determination of calcium channel blockers by using an experimental design approach. Chromatographia 61 (2005) 447-453
22. Novak M., and Seubert A. Application of experimental design for the characterization of a novel elution system for high capacity anion chromatography with suppressed conductivity detection. J. Chromatogr. A 855 (1999) 91-109
23. Box G.E.P., Hunter W.G., and Stuart Hunter J. Statistics for Experimenters-An Introduction to Design, Data Analysis and Model Building (1978), Wiley, New York
24. Bosque R., Sales J., Bosch E., Rosés M., Garcia-Alvarez-Coque M.C., and Torres-Lapasiò J.R. A QSPR study of the p solute polarity parameter to estimate retention in HPLC. J. Chem. Inf. Comput. Sci. 43 (2003) 1240-1247