Extracorporeal life support: Utilization, cost, controversy, and ethics of trying to Save lives

Seminars in Cardiothoracic and Vascular Anesthesia

Volumn 13, Issue 3, 2009, Pages 183-191

  Crow, Sheri ^a   Fischer, Anne C ^b   Schears, Raquel M ^a  

^a MAYO CLINIC   (United States)

^b Children's Medical Center   (United States)

Author keywords

Extracorporeal life support; Extracorporeal Life Support Organization (ELSO); Extracorporeal membrane oxygenation (ECMO)

Indexed keywords

CLINICAL TRIAL; EXTRACORPOREAL OXYGENATION; GROUPS BY AGE; HEALTH CARE COST; HEALTH CARE UTILIZATION; HEART FAILURE; HUMAN; MEDICAL ETHICS; PATIENT SELECTION; QUALITY OF LIFE; RESPIRATORY FAILURE; REVIEW; TREATMENT OUTCOME;

ADULT; CHILD; COST-BENEFIT ANALYSIS; EXTRACORPOREAL MEMBRANE OXYGENATION; HEART FAILURE; HUMANS; INFANT, NEWBORN; INSURANCE, HEALTH, REIMBURSEMENT; PATIENT SELECTION; QUALITY OF LIFE; RANDOMIZED CONTROLLED TRIALS AS TOPIC; RESPIRATORY INSUFFICIENCY;

EID: 70349309903     PISSN: 10892532     EISSN: None     Source Type: Journal    
DOI: 10.1177/1089253209347385     Document Type: Review

References (32)

1. Lewandowski K. Extracorporeal membrane oxygenation for severe acute respiratory failure. Crit Care. 2000 ; 4: 156-168.
2. Wolfson P. The development and use of extracorporeal membrane oxygenation in neonates. Ann Thorac Surg. 2003 ; 76: S2224 - S2229.
3. Hemmila MR, Rowe SA, Boules TN, et al. Extracorporeal life support for severe acute respiratory distress syndrome in adults. Ann Surg. 2004 ; 240: 595-607.
4. Conrad S., Rycus P., Dalton H. Extracorporeal Life Support Registry Report 2004. ASAIO J. 2005 ; 51: 4-10. (Pubitemid 40165243)
5. Shanley C., Hirschl RB, Schumacher RE, et al. Extracorporeal life support for neonatal respiratory failure a 20-year experience. Ann Surg. 1994 ; 220: 269-282.
6. Extracorporeal Life Support Organization. ECMO Registry of the Extracorporeal Life Support Organization (ELSO). Ann Arbor, MI: ELSO ; 2009.
7. Schuerer DJ, Kolovos NS, Boyd KV, Coopersmith CM Extracorporeal membrane oxygenation: current clinical practice, coding, and reimbursement. Chest. 2008 ; 134: 179-184.
8. Morris M., Ittenbach R., Godinez R., et al. Risk factors for mortality in 137 pediatric cardiac intensive care unit patients managed with extracorporeal membrane oxygenation. Crit Care Med. 2004 ; 32: 1061-1069.
9. Thalanany M., Mugford M., Hibbert C., et al. CESAR Trial Group. Methods of data collection and analysis for the economic evaluation alongside a national, multi-centre trial in the UK: conventional ventilation or ECMO for severe adult respiratory failure (CESAR). BMC Health Serv Res. 2008 ; 8: 94.
10. Peek G., Clemens F., Elbourne D., et al. CESAR: conventional ventilatory support vs extracorporeal membrane oxygenation for severe adult respiratory failure. BMC Health Serv Res. 2006 ; 6: 163.
11. Schumacher R., Roloff D., Chapman R., Snedecor S., Bartlett RH Extracorporeal membrane oxygenation in term newborns: a prospective cost-benefit analysis. ASAIO J. 1993 ; 39: 873-879.
12. Roberts TE Economic evaluation and randomized controlled trial of extracorporeal membrane oxygenation: UK collaborative trial. The Extracorporeal Membrane Oxygenation Economics Working Group. BMJ. 1998 ; 317: 911-916.
13. Petrou S., Bischof M., Bennett C., Elbourne D., Field D., McNally H. Cost-effectiveness of neonatal extracorporeal membrane oxygenation based on 7-year results from the United Kingdom Collaborative ECMO Trial. Pediatrics. 2006 ; 117: 1640-1649. (Pubitemid 46071391)
14. Van Litsenburg R., De Mos N., Edgell D., Gruenwald C., Bohn DJ, Parshuram CS Resource use and health outcomes of paediatric extracorporeal membrane oxygenation. Arch Dis Child Fetal Neonatal Ed. 2005 ; 90: F176 - F177.
15. Vats A., Pettignano R., Culler S., Wright J. Cost of extracorporeal life support in pediatric patients with acute respiratory failure. Crit Care Med. 1998 ; 26: 1587-1592.
16. Ayad O., Dietrich A., Mihalov L. Extracorporeal membrane oxygenation. Emerg Med Clin North Am. 2008 ; 26: 953-959.
17. Stevens A., Colin-Jones D., Gabbay J. Quick and clean: authoritative health technology assessment for local health care contracting. Health Trends. 1995 ; 27: 37-42.
18. Mugford M., Elbourne D., Field D. Extracorporeal membrane oxygenation for severe respiratory failure in newborn infants. Cochrane Database Syst Rev. 2007 ;(4) CD001340. doi:10.1002/14651858.CD001340.pub2.
19. Bartlett RH, Roloff DW, Custer JR, Younger JG, Hirschl RB Extracorporeal life support: the University of Michigan experience. JAMA. 2000 ; 283: 904-908.
20. Heyland DK, Konopad E., Noseworthy TW, Johnston R., Gafni A. Is it 'worthwhile' to continue treating patients with a prolonged stay (>14 days) in the ICU? An economic evaluation. Chest. 1998 ; 114: 192-198.
21. Sznajder M, Aegerter P, Launois R, Merliere Y, Guidet B, CubRea. A cost-effectiveness analysis of stays in intensive care units. Intensive Care Med. 2001;27:146-153
22. King J. Elective surgery for asymptomatic, unruptured, intracranial aneurysms: a cost-effectiveness analysis. J Neurosurg 1995 83 403-412.
23. Sisk JE, Moskowitz AJ, Whang W., et al. Cost effectiveness of vaccination against pneumococcal bacteremia among elderly people. JAMA. 1997 ; 278: 1333-1339.
24. The U.S. Organ Procurement and Transplantation Network and the Scientific Registry of Transplant Recipients UNOS; Arbor Research Collaborative for Health 2007 OPTN/SRTR Annual Report: Transplant Data 1997-2006.
25. Schmidt CD, Elliott CG, Carmelli D., et al. Prolonged mechanical ventilation for respiratory failure: a cost-benefit analysis. Crit Care Med. 1983 ; 11: 407-411.
26. Mugford M. The cost of neonatal care: reviewing the evidence. Soc Prev Med. 1995 ; 40: 361-368.
27. Bartlett RH, Roloff DW, Cornell RG, Andrews AF, Dillon PW, Zwischenberger JB Extracorporeal circulation in neonatal respiratory failure: a prospective randomized study. Pediatrics. 1985 ; 76: 479-487.
28. Toomasian JM, Snedecor SM, Cornell RG, et al. National experience with extracorporeal membrane oxygenation for newborn respiratory failure. Data from 715 cases. ASAIO Trans. 1988 ; 34: 140-147.
29. Bartlett RH, Andrews AF, Toomasian JM, Haiduc NJ, Gazzaniga AB Extracorporeal membrane oxygenation (ECMO) for newborn respiratory failure: forty-five cases. Surgery. 1982 ; 92: 425-433.
30. O'Rourke PP, Crone R., Vacanti J. Extracorporeal membrane oxygenation and conventional medical therapy in neonates with persistent pulmonary hypertension of the newborn: a prospective randomized study. Pediatrics. 1989 ; 84: 957-963.
31. UK collaborative randomised trial of neonatal extracorporeal membrane oxygenation. Lancet. 1996 ;348: 75-82.
32. Declaration of Helsinki: Ethical Principles for Medical Research Involving Human Subjects. http://www.wmw.et/e/policy/b3.htm. Accessed July 4, 2009.