Nucleostemin: A latecomer with new tricks

International Journal of Biochemistry and Cell Biology

Volumn 41, Issue 11, 2009, Pages 2122-2124

  Tsai, Robert Y L ^a   Meng, Lingjun ^a  

^a TEXAS A AND M HEALTH SCIENCE CENTER   (United States)

Author keywords

GNL3; GNL3L; Nucleostemin; Regeneration; Stem cells

Indexed keywords

GUANINE NUCLEOTIDE BINDING PROTEIN LIKE 3; GUANOSINE TRIPHOSPHATASE; NUCLEOSTEMIN; RIBOSOME PROTEIN; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; CARCINOGENESIS; CELL CYCLE REGULATION; CELL DEDIFFERENTIATION; CELL RENEWAL; CELL TRANSDIFFERENTIATION; MOLECULAR EVOLUTION; NEURAL STEM CELL; NONHUMAN; PROTEIN EXPRESSION; PROTEIN INTERACTION; PROTEIN LOCALIZATION; PROTEIN STRUCTURE; SENESCENCE; SHORT SURVEY; TELOMERE; TISSUE REGENERATION; UPREGULATION;

ANIMALS; HUMANS; NUCLEAR PROTEINS; PROTEIN BINDING; PROTEIN TRANSPORT; REGENERATION; VERTEBRATES;

INVERTEBRATA; MAMMALIA; VERTEBRATA;

EID: 70349298364     PISSN: 13572725     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biocel.2009.05.020     Document Type: Short Survey

References (22)

1. Baddoo M., Hill K., Wilkinson R., Gaupp D., Hughes C., Kopen G.C., et al. Characterization of mesenchymal stem cells isolated from murine bone marrow by negative selection. J Cell Biochem 89 (2003) 1235-1249
2. Bassler J., Grandi P., Gadal O., Lessmann T., Petfalski E., Tollervey D., et al. Identification of a 60S preribosomal particle that is closely linked to nuclear export. Mol Cell 8 (2001) 517-529
3. Beekman C., Nichane M., De Clercq S., Maetens M., Floss T., Wurst W., et al. Evolutionarily conserved role of nucleostemin: controlling proliferation of stem/progenitor cells during early vertebrate development. Mol Cell Biol 26 (2006) 9291-9301
4. Dai M.S., Sun X.X., and Lu H. Aberrant expression of nucleostemin activates p53 and induces cell cycle arrest via inhibition of MDM2. Mol Cell Biol 28 (2008) 4365-4376
5. Du X., Rao M.R., Chen X.Q., Wu W., Mahalingam S., and Balasundaram D. The homologous putative GTPases Grn1p from fission yeast and the human GNL3L are required for growth and play a role in processing of nucleolar pre-rRNA. Mol Biol Cell 17 (2006) 460-474
6. Fu D., and Collins K. Purification of human telomerase complexes identifies factors involved in telomerase biogenesis and telomere length regulation. Mol Cell 28 (2007) 773-785
7. Kaplan D.D., Zimmermann G., Suyama K., Meyer T., and Scott M.P. A nucleostemin family GTPase, NS3, acts in serotonergic neurons to regulate insulin signaling and control body size. Genes Dev 22 (2008) 1877-1893
8. Kudron M.M., and Reinke V.C. C. elegans nucleostemin is required for larval growth and germline stem cell division. PLoS Genet 4 (2008) e1000181
9. Leipe D.D., Wolf Y.I., Koonin E.V., and Aravind L. Classification and evolution of P-loop GTPases and related ATPases. J Mol Biol 317 (2002) 41-72
10. Ma H., and Pederson T. Depletion of the nucleolar protein nucleostemin causes G1 cell cycle arrest via the p53 pathway. Mol Biol Cell 18 (2007) 2630-2635
11. Maki N., Takechi K., Sano S., Tarui H., Sasai Y., and Agata K. Rapid accumulation of nucleostemin in nucleolus during newt regeneration. Dev Dyn 236 (2007) 941-950
12. Meng L., Lin T., and Tsai R.Y. Nucloplasmic mobilization of nucleostemin stabilizes MDM2 and promotes G2-M progression and cell survival. J Cell Sci 121 (2008) 4037-4046
13. Meng L., Yasumoto H., and Tsai R.Y. Multiple controls regulate nucleostemin partitioning between nucleolus and nucleoplasm. J Cell Sci 119 (2006) 5124-5136
14. Ohmura M., Naka K., Hoshii T., Muraguchi T., Shugo H., Tamase A., et al. Identification of stem cells during prepubertal spermatogenesis via monitoring of nucleostemin promoter activity. Stem Cells 26 (2008) 3237-3246
15. Politz J.C., Polena I., Trask I., Bazett-Jones D.P., and Pederson T. A nonribosomal landscape in the nucleolus revealed by the stem cell protein nucleostemin. Mol Biol Cell 16 (2005) 3401-3410
16. Romanova L., Grand A., Zhang L., Rayner S., Katoku-Kikyo N., Kellner S., et al. Critical role of nucleostemin in pre-rRNA processing. J Biol Chem 284 (2009) 4968-4977
17. Siddiqi S., Gude N., Hosoda T., Muraski J., Rubio M., Emmanuel G., et al. Myocardial induction of nucleostemin in response to postnatal growth and pathological challenge. Circ Res 103 (2008) 89-97
18. Tsai R.Y., and McKay R.D. A nucleolar mechanism controlling cell proliferation in stem cells and cancer cells. Genes Dev 16 (2002) 2991-3003
19. Tsai R.Y., and McKay R.D. A multistep, GTP-driven mechanism controlling the dynamic cycling of nucleostemin. J Cell Biol 168 (2005) 179-184
20. Yasumoto H., Meng L., Lin T., Zhu Q., and Tsai R.Y. GNL3L inhibits activity of estrogen-related receptor {gamma} by competing for coactivator binding. J Cell Sci 120 (2007) 2532-2543
21. Zhu Q., Meng L., Hsu J.K., Lin T., Teishima J., and Tsai R.Y. GNL3L stabilizes the TRF1 complex and promotes mitotic transition. J Cell Biol 185 (2009) 827-839
22. Zhu Q., Yasumoto H., and Tsai R.Y. Nucleostemin delays cellular senescence and negatively regulates TRF1 protein stability. Mol Cell Biol 26 (2006) 9279-9290