메뉴 건너뛰기




Volumn 259, Issue 7, 2009, Pages 383-393

Cannabis use in pregnancy and early life and its consequences: Animal models

Author keywords

Animal models; Cannabinoids; CB1 receptor; Postnatal; Pregnancy; Prenatal

Indexed keywords

AMPHETAMINE; CANNABINOL; CANNABIS; COCAINE; DIAMORPHINE; ENDOCANNABINOID; MORPHINE; TETRAHYDROCANNABINOL;

EID: 70349295197     PISSN: 09401334     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00406-009-0026-0     Document Type: Review
Times cited : (76)

References (69)
  • 1
    • 0019310136 scopus 로고
    • Prenatal exposure to cannabis: A critical review of effects on growth, development, and behavior
    • EL Abel 1980 Prenatal exposure to cannabis: a critical review of effects on growth, development, and behavior Behav Neural Biol 29 137 156
    • (1980) Behav Neural Biol , vol.29 , pp. 137-156
    • Abel, E.L.1
  • 3
    • 70349300302 scopus 로고
    • Inhibition of postnatal maternal performance in rats treated with marijuana extract during pregnancy
    • EL Abel N Day BA Dintcheff CAS Ernst 1979 Inhibition of postnatal maternal performance in rats treated with marijuana extract during pregnancy Bull Psychon Soc 4 353 359
    • (1979) Bull Psychon Soc , vol.4 , pp. 353-359
    • Abel, E.L.1    Day, N.2    Dintcheff, B.A.3    Ernst, C.A.S.4
  • 4
    • 27744470790 scopus 로고    scopus 로고
    • Prenatal exposure to the CB1 receptor agonist WIN 55, 212-2 causes learning disruption associated with impaired cortical NMDA receptor function and emotional reactivity changes in rat offspring
    • T Antonelli MC Tomasini M Tattoli T Cassano S Tanganelli S Finetti E Mazzoni L Trabace L Steardo V Cuomo L Ferraro 2005 Prenatal exposure to the CB1 receptor agonist WIN 55, 212-2 causes learning disruption associated with impaired cortical NMDA receptor function and emotional reactivity changes in rat offspring Cereb Cortex 15 2013 2020
    • (2005) Cereb Cortex , vol.15 , pp. 2013-2020
    • Antonelli, T.1    Tomasini, M.C.2    Tattoli, M.3    Cassano, T.4    Tanganelli, S.5    Finetti, S.6    Mazzoni, E.7    Trabace, L.8    Steardo, L.9    Cuomo, V.10    Ferraro, L.11
  • 5
    • 40849136049 scopus 로고    scopus 로고
    • Sex-dependent effects of periadolescent exposure to the c cannabinoid agonist CP-55, 940 on morphine self-administration behaviour and the endogenous opioid system
    • M Biscaia B Fernandez A Higuera-Matas M Miguens MP Viveros C Garcia-Lecumberri E Ambrosio 2008 Sex-dependent effects of periadolescent exposure to the c cannabinoid agonist CP-55, 940 on morphine self-administration behaviour and the endogenous opioid system Neuropharmacology 54 863 873
    • (2008) Neuropharmacology , vol.54 , pp. 863-873
    • Biscaia, M.1    Fernandez, B.2    Higuera-Matas, A.3    Miguens, M.4    Viveros, M.P.5    Garcia-Lecumberri, C.6    Ambrosio, E.7
  • 6
    • 0344082222 scopus 로고    scopus 로고
    • Chronic treatment with CP 55, 940 during the peri-adolescent period differentially affects the behavioural responses of male and female rats in adulthood
    • M Biscaia S Marin B Fernandez EM Marco M Rubio C Guaza E Ambrosio MP Viveros 2003 Chronic treatment with CP 55, 940 during the peri-adolescent period differentially affects the behavioural responses of male and female rats in adulthood Psychopharmacology 170 301 308
    • (2003) Psychopharmacology , vol.170 , pp. 301-308
    • Biscaia, M.1    Marin, S.2    Fernandez, B.3    Marco, E.M.4    Rubio, M.5    Guaza, C.6    Ambrosio, E.7    Viveros, M.P.8
  • 7
    • 50549214560 scopus 로고
    • The ontogeny of behaviour in the albino rat
    • RC Bolles PJ Woods 1964 The ontogeny of behaviour in the albino rat Anim Behav 12 427 441
    • (1964) Anim Behav , vol.12 , pp. 427-441
    • Bolles, R.C.1    Woods, P.J.2
  • 9
    • 0014697589 scopus 로고
    • Ontogeny of adrenergic arousal and cholinergic inhibitory mechanisms in the rat
    • BA Campbell LD Lytle HC Fibiger 1969 Ontogeny of adrenergic arousal and cholinergic inhibitory mechanisms in the rat Science 166 635 637
    • (1969) Science , vol.166 , pp. 635-637
    • Campbell, B.A.1    Lytle, L.D.2    Fibiger, H.C.3
  • 11
    • 0022526019 scopus 로고
    • Cannabinoid exposure: Effects on development
    • SL Dalterio 1986 Cannabinoid exposure: effects on development Neurobehav Toxicol Teratol 8 345 352
    • (1986) Neurobehav Toxicol Teratol , vol.8 , pp. 345-352
    • Dalterio, S.L.1
  • 12
    • 0018372689 scopus 로고
    • Comparative aspects of the brain growth spurt
    • J Dobbing J Sands 1979 Comparative aspects of the brain growth spurt Early Hum Dev 3 79 83
    • (1979) Early Hum Dev , vol.3 , pp. 79-83
    • Dobbing, J.1    Sands, J.2
  • 14
    • 33847008322 scopus 로고    scopus 로고
    • Adolescent cannabis exposure alters opiate intake and opioid limbic neuronal populations in adult rats
    • M Ellgren SM Spano YL Hurd 2007 Adolescent cannabis exposure alters opiate intake and opioid limbic neuronal populations in adult rats Neuropsychopharmacology 32 607 615
    • (2007) Neuropsychopharmacology , vol.32 , pp. 607-615
    • Ellgren, M.1    Spano, S.M.2    Hurd, Y.L.3
  • 15
    • 33645642113 scopus 로고    scopus 로고
    • Neuroplasticity of the hypothalamic-pituitary- adrenal axis early in life requires recurrent recruitment of stress-regulating brain regions
    • KA Fenoglio Y Chen TZ Baram 2006 Neuroplasticity of the hypothalamic-pituitary- adrenal axis early in life requires recurrent recruitment of stress-regulating brain regions J Neurosci 26 2434 2442
    • (2006) J Neurosci , vol.26 , pp. 2434-2442
    • Fenoglio, K.A.1    Chen, Y.2    Baram, T.Z.3
  • 18
    • 4644282275 scopus 로고    scopus 로고
    • The endocannabinoid-CB(1) receptor system in pre- and postnatal life
    • E Fride 2004 The endocannabinoid-CB(1) receptor system in pre- and postnatal life Eur J Pharmacol 500 289 297
    • (2004) Eur J Pharmacol , vol.500 , pp. 289-297
    • Fride, E.1
  • 19
    • 0035077403 scopus 로고    scopus 로고
    • A literature review of the consequences of prenatal marihuana exposure-an emerging theme of a deficiency in aspects of executive functions
    • PA Fried AM Smith 2001 A literature review of the consequences of prenatal marihuana exposure-an emerging theme of a deficiency in aspects of executive functions Neurotoxicol Teratol 23 1 11 11274871
    • (2001) Neurotoxicol Teratol , vol.23 , pp. 1-11
    • Fried, P.A.1    Smith, A.M.2
  • 20
    • 56849126270 scopus 로고    scopus 로고
    • Neonatal handling on the first postnatal day leads to increased maternal behavior and fos levels in the brain of the newborn rat
    • E Garoflos A Stamatakis A Rafrogianni S Pondiki F Stylianopoulou 2008 Neonatal handling on the first postnatal day leads to increased maternal behavior and fos levels in the brain of the newborn rat Dev Psychobiol 00 1 10
    • (2008) Dev Psychobiol , vol.0 , pp. 1-10
    • Garoflos, E.1    Stamatakis, A.2    Rafrogianni, A.3    Pondiki, S.4    Stylianopoulou, F.5
  • 21
    • 0035176184 scopus 로고    scopus 로고
    • CB1 cannabinoid receptor inhibits synaptic release of glutamate in rat dorsolateral striatum
    • G Gerdeman DM Lovinger 2001 CB1 cannabinoid receptor inhibits synaptic release of glutamate in rat dorsolateral striatum J Neurophysiol 85 468 471
    • (2001) J Neurophysiol , vol.85 , pp. 468-471
    • Gerdeman, G.1    Lovinger, D.M.2
  • 25
    • 0035337711 scopus 로고    scopus 로고
    • Presynaptic mechanisms underlying cannabinoid inhibition of excitatory synaptic transmission in rat striatal neurons
    • CC Huang SW Lo KS Hsu 2001 Presynaptic mechanisms underlying cannabinoid inhibition of excitatory synaptic transmission in rat striatal neurons J Physiol 532 731 748 11313442
    • (2001) J Physiol , vol.532 , pp. 731-748
    • Huang, C.C.1    Lo, S.W.2    Hsu, K.S.3
  • 26
    • 0024505292 scopus 로고
    • Plasma concentrations of delta-9-tetrahydrocannabinol in dams and fetuses following acute or multiple prenatal dosing in rats
    • DE Hutchings BR Martin Z Gamagaris N Miller T Fico 1989 Plasma concentrations of delta-9-tetrahydrocannabinol in dams and fetuses following acute or multiple prenatal dosing in rats Life Sci 44 697 701
    • (1989) Life Sci , vol.44 , pp. 697-701
    • Hutchings, D.E.1    Martin, B.R.2    Gamagaris, Z.3    Miller, N.4    Fico, T.5
  • 28
    • 0015621781 scopus 로고
    • Radioactivity in suckled rats after giving 14 C- tetrahydrocannabinol to the mother
    • A Jakubovic T Hattori PL McGeer 1973 Radioactivity in suckled rats after giving 14 C- tetrahydrocannabinol to the mother Eur J Pharmacol 22 221 223
    • (1973) Eur J Pharmacol , vol.22 , pp. 221-223
    • Jakubovic, A.1    Hattori, T.2    McGeer, P.L.3
  • 29
    • 0019310877 scopus 로고
    • Effects of administration of cannabis resin during pregnancy on emotionality and learning in rats' offspring
    • GF Kawash DL Yeung SD Berg 1980 Effects of administration of cannabis resin during pregnancy on emotionality and learning in rats' offspring Percept Mot Skills 50 359 365
    • (1980) Percept Mot Skills , vol.50 , pp. 359-365
    • Kawash, G.F.1    Yeung, D.L.2    Berg, S.D.3
  • 30
    • 0024487341 scopus 로고
    • Plasticity in the neocortex: Mechanisms underlying recovery from early brain damage
    • B Kolb IQ Whishaw 1989 Plasticity in the neocortex: mechanisms underlying recovery from early brain damage Prog Neurobiol 32 235 276
    • (1989) Prog Neurobiol , vol.32 , pp. 235-276
    • Kolb, B.1    Whishaw, I.Q.2
  • 31
    • 0025163701 scopus 로고
    • Effect of early exposure to delta-9-tetrahydrocannabinol on the levels of opioid peptides, gonadotropin-releasing hormone and substance P in the adult male rat brain
    • AM Kumar M Haney T Becker ML Thompson RM Kream K Miczek 1990 Effect of early exposure to delta-9-tetrahydrocannabinol on the levels of opioid peptides, gonadotropin-releasing hormone and substance P in the adult male rat brain Brain Res 525 78 83
    • (1990) Brain Res , vol.525 , pp. 78-83
    • Kumar, A.M.1    Haney, M.2    Becker, T.3    Thompson, M.L.4    Kream, R.M.5    Miczek, K.6
  • 33
    • 34347394152 scopus 로고    scopus 로고
    • Early maternal deprivation and neonatal single administration with a cannabinoid agonist induce long-term sex-dependent psychoimmunoendocrine effects in adolescent rats
    • R Llorente L Arranz EM Marco E Moreno M Puerto C Guaza M De la Fuente MP Viveros 2007 Early maternal deprivation and neonatal single administration with a cannabinoid agonist induce long-term sex-dependent psychoimmunoendocrine effects in adolescent rats Psychoneuroendocrinology 32 636 650
    • (2007) Psychoneuroendocrinology , vol.32 , pp. 636-650
    • Llorente, R.1    Arranz, L.2    Marco, E.M.3    Moreno, E.4    Puerto, M.5    Guaza, C.6    De La Fuente, M.7    Viveros, M.P.8
  • 34
    • 0014933381 scopus 로고
    • Marihuana chemistry
    • R Mechoulam 1970 Marihuana chemistry Science 168 1159 1166
    • (1970) Science , vol.168 , pp. 1159-1166
    • Mechoulam, R.1
  • 37
    • 0023370167 scopus 로고
    • Neonatal administration of delta-9-tetrahydrocannabinol (THC) alters the neurochemical response to stress in the adult Fischer-344 rat
    • DJ Mokler SE Robinson JH Johnson JS Hong JA Rosecrans 1987 Neonatal administration of delta-9-tetrahydrocannabinol (THC) alters the neurochemical response to stress in the adult Fischer-344 rat Neurotoxicol Teratol 9 321 327
    • (1987) Neurotoxicol Teratol , vol.9 , pp. 321-327
    • Mokler, D.J.1    Robinson, S.E.2    Johnson, J.H.3    Hong, J.S.4    Rosecrans, J.A.5
  • 38
    • 43949084075 scopus 로고    scopus 로고
    • The endocannabinoid system: Emotion, learning and addiction
    • FA Moreira B Lutz 2008 The endocannabinoid system: emotion, learning and addiction Addict Biol 13 196 212
    • (2008) Addict Biol , vol.13 , pp. 196-212
    • Moreira, F.A.1    Lutz, B.2
  • 39
    • 26044453633 scopus 로고    scopus 로고
    • Long-term behavioural and neuroendocrine effects of perinatal activation or blockade of CB1 cannabinoid receptors
    • M Moreno L Escuredo R Munoz dF Rodriguez M Navarro 2005 Long-term behavioural and neuroendocrine effects of perinatal activation or blockade of CB1 cannabinoid receptors Behav Pharmacol 16 423 430
    • (2005) Behav Pharmacol , vol.16 , pp. 423-430
    • Moreno, M.1    Escuredo, L.2    Munoz, R.3    Df, R.4    Navarro, M.5
  • 40
    • 0028841944 scopus 로고
    • Behavioural consequences of maternal exposure to natural cannabinoids in rats
    • M Navarro P Rubio FR de Fonseca 1995 Behavioural consequences of maternal exposure to natural cannabinoids in rats Psychopharmacology 122 1 14
    • (1995) Psychopharmacology , vol.122 , pp. 1-14
    • Navarro, M.1    Rubio, P.2    De Fonseca, F.R.3
  • 41
    • 0027967868 scopus 로고
    • Sex-dimorphic psychomotor activation after perinatal exposure to (-)-D9-tetrahadrocannabinol. An ontogenic study in Wistar rats
    • M Navarro T Rubio F Rodriguez de Fonseca 1994 Sex-dimorphic psychomotor activation after perinatal exposure to (-)-D9-tetrahadrocannabinol. An ontogenic study in Wistar rats Psychopharmacology 116 414 422
    • (1994) Psychopharmacology , vol.116 , pp. 414-422
    • Navarro, M.1    Rubio, T.2    Rodriguez De Fonseca, F.3
  • 42
    • 44149112787 scopus 로고    scopus 로고
    • Perinatal delta-9-tetrahydrocannabinol exposure disrupts social and open field behavior in adult male rats
    • RJ Newsom SJ Kelly 2008 Perinatal delta-9-tetrahydrocannabinol exposure disrupts social and open field behavior in adult male rats Neurotoxicol Teratol 30 213 219
    • (2008) Neurotoxicol Teratol , vol.30 , pp. 213-219
    • Newsom, R.J.1    Kelly, S.J.2
  • 43
    • 26044458941 scopus 로고    scopus 로고
    • Impaired learning in adulthood following neonatal delta9- THC exposure
    • M O'Shea PE Mallet 2005 Impaired learning in adulthood following neonatal delta9- THC exposure Behav Pharmacol 16 455 461
    • (2005) Behav Pharmacol , vol.16 , pp. 455-461
    • O'Shea, M.1    Mallet, P.E.2
  • 44
    • 33748206802 scopus 로고    scopus 로고
    • Repeated cannabinoid exposure during perinatal, adolescent or early adult ages produces similar longlasting deficits in object recognition and reduced social interaction in rats
    • M O'Shea IS McGregor PE Mallet 2006 Repeated cannabinoid exposure during perinatal, adolescent or early adult ages produces similar longlasting deficits in object recognition and reduced social interaction in rats J Psychopharmacol 20 611 621
    • (2006) J Psychopharmacol , vol.20 , pp. 611-621
    • O'Shea, M.1    McGregor, I.S.2    Mallet, P.E.3
  • 45
    • 10844280077 scopus 로고    scopus 로고
    • Chronic cannabinoid exposure produces lasting memory impairment and increased anxiety in adolescent but not adult rats
    • M O'Shea ME Singh IS McGregor PE Mallet 2004 Chronic cannabinoid exposure produces lasting memory impairment and increased anxiety in adolescent but not adult rats J Psychopharmacol 18 502 508
    • (2004) J Psychopharmacol , vol.18 , pp. 502-508
    • O'Shea, M.1    Singh, M.E.2    McGregor, I.S.3    Mallet, P.E.4
  • 46
    • 0001372320 scopus 로고
    • Puberty in the rat
    • E. Knobil J.D. Neill (eds). Raven Press New York
    • Ojeda SR, Urbanski HF (1994) Puberty in the rat. In: Knobil E, Neill JD (eds) The physiology of reproduction. Raven Press, New York, pp 363-410
    • (1994) The Physiology of Reproduction , pp. 363-410
    • Ojeda, S.R.1    Urbanski, H.F.2
  • 47
    • 22144447474 scopus 로고    scopus 로고
    • Strong increase in total delta-THC in cannabis preparations sold in Dutch coffee shops
    • FT Pijlman SM Rigter J Hoek HM Goldschmidt RJ Niesink 2005 Strong increase in total delta-THC in cannabis preparations sold in Dutch coffee shops Addict Biol 10 171 180
    • (2005) Addict Biol , vol.10 , pp. 171-180
    • Pijlman, F.T.1    Rigter, S.M.2    Hoek, J.3    Goldschmidt, H.M.4    Niesink, R.J.5
  • 48
    • 3042752521 scopus 로고    scopus 로고
    • Adolescent exposure to cannabinoids induces long-lasting changes in the response to drugs of abuse of rat midbrain dopamine neurons
    • M Pistis S Perra G Pillolla M Melis AL Muntoni GL Gessa 2004 Adolescent exposure to cannabinoids induces long-lasting changes in the response to drugs of abuse of rat midbrain dopamine neurons Biol Psychiatry 56 86 94
    • (2004) Biol Psychiatry , vol.56 , pp. 86-94
    • Pistis, M.1    Perra, S.2    Pillolla, G.3    Melis, M.4    Muntoni, A.L.5    Gessa, G.L.6
  • 49
    • 39049124647 scopus 로고    scopus 로고
    • Potency of delta 9-THC and other cannabinoids in cannabis in England in 2005: Implications for psychoactivity and pharmacology
    • DJ Potter P Clark MB Brown 2008 Potency of delta 9-THC and other cannabinoids in cannabis in England in 2005: implications for psychoactivity and pharmacology J Forensic Sci 53 90 94
    • (2008) J Forensic Sci , vol.53 , pp. 90-94
    • Potter, D.J.1    Clark, P.2    Brown, M.B.3
  • 53
    • 0029039783 scopus 로고
    • Long-term behavioral effects of perinatal exposure to delta 9- tetrahydrocannabinol in rats: Possible role of pituitary-adrenal axis
    • P Rubio F Rodriguez de Fonseca RM Munoz C Ariznavarreta JL Martin-Calderon M Navarro 1995 Long-term behavioral effects of perinatal exposure to delta 9- tetrahydrocannabinol in rats: possible role of pituitary-adrenal axis Life Sci 56 2169 2176
    • (1995) Life Sci , vol.56 , pp. 2169-2176
    • Rubio, P.1    Rodriguez De Fonseca, F.2    Munoz, R.M.3    Ariznavarreta, C.4    Martin-Calderon, J.L.5    Navarro, M.6
  • 54
    • 43749124806 scopus 로고    scopus 로고
    • Puberty as a highly vulnerable developmental period for the consequences of cannabis exposure
    • M Schneider 2008 Puberty as a highly vulnerable developmental period for the consequences of cannabis exposure Addict Biol 13 2 253 263
    • (2008) Addict Biol , vol.13 , Issue.2 , pp. 253-263
    • Schneider, M.1
  • 55
    • 26044438805 scopus 로고    scopus 로고
    • Behavioral effects in adult rats of chronic prepubertal treatment with the cannabinoid receptor agonist WIN 55, 212-2
    • M Schneider E Drews M Koch 2005 Behavioral effects in adult rats of chronic prepubertal treatment with the cannabinoid receptor agonist WIN 55, 212-2 Behav Pharmacol 16 447 454
    • (2005) Behav Pharmacol , vol.16 , pp. 447-454
    • Schneider, M.1    Drews, E.2    Koch, M.3
  • 56
    • 0642338928 scopus 로고    scopus 로고
    • Chronic pubertal, but not adult chronic cannabinoid treatment impairs sensorimotor gating, recognition memory and the performance in a progressive ratio task in adult rats
    • Schneider M, Koch M (2003) Chronic pubertal, but not adult chronic cannabinoid treatment impairs sensorimotor gating, recognition memory and the performance in a progressive ratio task in adult rats. Neuropsychopharmacology 28:1760-1769
    • (2003) Neuropsychopharmacology , vol.28 , pp. 1760-1769
    • Schneider, M.1    Koch, M.2
  • 57
    • 17644408388 scopus 로고    scopus 로고
    • Deficient social and play behavior in juvenile and adult rats after neonatal cortical lesion: Effects of chronic pubertal cannabinoid treatment
    • M Schneider M Koch 2005 Deficient social and play behavior in juvenile and adult rats after neonatal cortical lesion: effects of chronic pubertal cannabinoid treatment Neuropsychopharmacology 30 944 957
    • (2005) Neuropsychopharmacology , vol.30 , pp. 944-957
    • Schneider, M.1    Koch, M.2
  • 58
    • 49349108613 scopus 로고    scopus 로고
    • Acute and chronic cannabinoid treatment differentially affects recognition memory and social behavior in pubertal and adult rats
    • M Schneider E Schoemig FM Leweke 2008 Acute and chronic cannabinoid treatment differentially affects recognition memory and social behavior in pubertal and adult rats Addict Biol 13 345 357
    • (2008) Addict Biol , vol.13 , pp. 345-357
    • Schneider, M.1    Schoemig, E.2    Leweke, F.M.3
  • 59
    • 32844454765 scopus 로고    scopus 로고
    • Perinatal exposure to delta(9)- tetrahydrocannabinol alters heroin-induced place conditioning and fos- immunoreactivity
    • ME Singh IS McGregor PE Mallet 2006 Perinatal exposure to delta(9)- tetrahydrocannabinol alters heroin-induced place conditioning and fos- immunoreactivity Neuropsychopharmacology 31 58 69
    • (2006) Neuropsychopharmacology , vol.31 , pp. 58-69
    • Singh, M.E.1    McGregor, I.S.2    Mallet, P.E.3
  • 60
    • 40749093572 scopus 로고    scopus 로고
    • Effects of neonatal handling on play behavior and fear towards a predator odor in juvenile rats (Rattus norvegicus)
    • SM Siviy KA Harrison 2008 Effects of neonatal handling on play behavior and fear towards a predator odor in juvenile rats (Rattus norvegicus) J Comp Psychol 122 1 8
    • (2008) J Comp Psychol , vol.122 , pp. 1-8
    • Siviy, S.M.1    Harrison, K.A.2
  • 61
    • 33846574184 scopus 로고    scopus 로고
    • Prenatal cannabis exposure increases heroin seeking with allostatic changes in limbic enkephalin systems in adulthood
    • MS Spano M Ellgren X Wang YL Hurd 2007 Prenatal cannabis exposure increases heroin seeking with allostatic changes in limbic enkephalin systems in adulthood Biol Psychiatry 61 554 563
    • (2007) Biol Psychiatry , vol.61 , pp. 554-563
    • Spano, M.S.1    Ellgren, M.2    Wang, X.3    Hurd, Y.L.4
  • 63
    • 44549088054 scopus 로고    scopus 로고
    • Effects of perinatal exposure to delta-9-tetrahydrocannabinol on the emotional reactivity of the offspring: A longitudinal behavioral study in Wistar rats
    • V Trezza P Campolongo T Cassano T Macheda P Dipasquale MR Carratu S Gaetani V Cuomo 2008 Effects of perinatal exposure to delta-9- tetrahydrocannabinol on the emotional reactivity of the offspring: a longitudinal behavioral study in Wistar rats Psychopharmacology (Berl) 198 529 537
    • (2008) Psychopharmacology (Berl) , vol.198 , pp. 529-537
    • Trezza, V.1    Campolongo, P.2    Cassano, T.3    MacHeda, T.4    Dipasquale, P.5    Carratu, M.R.6    Gaetani, S.7    Cuomo, V.8
  • 64
    • 0028990219 scopus 로고
    • Perinatal exposure to delta 9-tetrahydrocannabinol (delta 9-THC) leads to changes in opioid- related behavioral patterns in rats
    • G Vela JA Fuentes A Bonnin J Fernandez-Ruiz M Ruiz-Gayo 1995 Perinatal exposure to delta 9-tetrahydrocannabinol (delta 9-THC) leads to changes in opioid- related behavioral patterns in rats Brain Res 680 142 147
    • (1995) Brain Res , vol.680 , pp. 142-147
    • Vela, G.1    Fuentes, J.A.2    Bonnin, A.3    Fernandez-Ruiz, J.4    Ruiz-Gayo, M.5
  • 66
    • 55049118059 scopus 로고    scopus 로고
    • Neonatal ketamine exposure results in changes in biochemical substrates of neuronal growth and synaptogenesis, and alters adult behavior irreversibly
    • H Viberg E Ponten P Eriksson T Gordh A Fredriksson 2008 Neonatal ketamine exposure results in changes in biochemical substrates of neuronal growth and synaptogenesis, and alters adult behavior irreversibly Toxicology 249 153 159
    • (2008) Toxicology , vol.249 , pp. 153-159
    • Viberg, H.1    Ponten, E.2    Eriksson, P.3    Gordh, T.4    Fredriksson, A.5
  • 67
    • 53749095085 scopus 로고    scopus 로고
    • Loss of cannabinoid receptor CB1 induces preterm birth
    • H Wang H Xie SK Dey 2008 Loss of cannabinoid receptor CB1 induces preterm birth PLoS ONE 3 e3320
    • (2008) PLoS ONE , vol.3
    • Wang, H.1    Xie, H.2    Dey, S.K.3
  • 68
    • 54249156391 scopus 로고    scopus 로고
    • Cannabidiol: From an inactive cannabinoid to a drug with wide spectrum of action
    • AW Zuardi 2008 Cannabidiol: from an inactive cannabinoid to a drug with wide spectrum of action Rev Bras Psiquiatr 30 271 280
    • (2008) Rev Bras Psiquiatr , vol.30 , pp. 271-280
    • Zuardi, A.W.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.