Magnetic resonance imaging of cells overexpressing maga, an endogenous contrast agent for live cell imaging

Molecular Imaging

Volumn 8, Issue 3, 2009, Pages 129-139

  Goldhawk, Donna E ^a   Lemaire, Claude ^b   McCreary, Cheryl R ^b   McGirr, Rebecca ^b   Dhanvantari, Savita ^b   Thompson, R Terry ^b   Figueredo, Rene ^b   Koropatnick, Jim ^b   Foster, Paula ^b   Prato, Frank S ^b  

^a LAWSON HEALTH RESEARCH INSTITUTE   (Canada)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

BIOMINERALS; CELLULAR IMAGING; CONTRAST AGENT; ELEMENTAL IRON; FERRIMAGNETIC PROPERTIES; FIELD OF VIEWS; IRON LOADING; IRON TRANSPORTER; LIVE-CELL IMAGING; MAGNETOSOMES; MAGNETOTACTIC BACTERIA; MAMMALIAN CELLS; MOLECULAR IMAGING; MRI REPORTER GENES; MULTIPLE GENES; N2A CELLS; NEUROBLASTOMAS; PRUSSIAN BLUE; SINGLE-POINT MUTATION; SPIN ECHO; STABLE EXPRESSION; SUPERIOR RESOLUTION;

CELL CULTURE; CELL PROLIFERATION; MAGNETIC RESONANCE; MAGNETIC RESONANCE IMAGING; MAMMALS; MEDICAL IMAGING;

CELL MEMBRANES;

BACTERIAL PROTEIN; CATION TRANSPORT PROTEIN; CONTRAST MEDIUM; GREEN FLUORESCENT PROTEIN; HYBRID PROTEIN; IRON; MAGA PROTEIN, MAGNETOSPIRILLUM; ZINC;

ANIMAL; ARTICLE; BIOSYNTHESIS; BREAST TUMOR; CANCER TRANSPLANTATION; FEMALE; GENE EXPRESSION; GENETIC TRANSFECTION; GENETICS; HINDLIMB; HUMAN; MASS SPECTROMETRY; METABOLISM; METHODOLOGY; MOUSE; NEUROBLASTOMA; NUCLEAR MAGNETIC RESONANCE IMAGING; PATHOLOGY; TUMOR CELL LINE;

ANIMALS; BACTERIAL PROTEINS; BREAST NEOPLASMS; CATION TRANSPORT PROTEINS; CELL LINE, TUMOR; CONTRAST MEDIA; FEMALE; GENE EXPRESSION; GREEN FLUORESCENT PROTEINS; HINDLIMB; HUMANS; IRON; MAGNETIC RESONANCE IMAGING; MASS SPECTROMETRY; MICE; NEOPLASM TRANSPLANTATION; NEUROBLASTOMA; RECOMBINANT FUSION PROTEINS; TRANSFECTION; ZINC;

EID: 70349289256     PISSN: 15353508     EISSN: None     Source Type: Journal    
DOI: 10.2310/7290.2009.00006     Document Type: Article

References (33)

1. Arbab A, Bashaw L, Miller B, et al. Intracytoplasmic tagging of cells with ferumoxides and transfection agent for cellular magnetic resonance imaging after cell transplantation: methods and techniques. Transplantation 2003;76:1123-1130
2. Guzman R. Long-term monitoring of transplanted human neural stem cells in developmental and pathological contexts with MRI. Proc Natl Acad Sci U S A 2007;104:10211-10216
3. Serda RE, Adolphi NL, Bisoffi M, Sillerud LO. Targeting and cellular trafficking of magnetic nanoparticles for prostate cancer imaging. Mol Imaging 2007;6:277-288
4. Blackwood KJ, Sabondjian E, Goldhawk DE, et al. Towards image- guided stem cell therapy. In: Faraday AV, Dyer JT, editors. Progress in stem cell applications. New York: Nova Science; 2008. p. 153-180
5. Barnett B, Arepally A, Karmarkar P, et al. Magnetic resonance- guided, real-time targeted delivery and imaging of magnetocapsules immunoprotecting pancreatic islet cells. Nat Med 2007;13: 986-991
6. Tai J, Foster P, Rosales A, et al. Imaging islets labeled with magnetic nanoparticles at 1.5 Tesla. Diabetes 2006;55:2931-2938
7. Chambers AF, Groom AC, MacDonald IC. Dissemination and growth of cancer cells in metastatic sites. Nat Rev Cancer 2002;2: 563-572
8. Gilad A, Winnard P, van Zijl P, Bulte J. Developing MR reporter genes: promises and pitfalls. NMR Biomed 2007;20:275-290
9. Genove G, DeMarco U, Xu H, et al. A new transgene reporter for in vivo magnetic resonance imaging. Nat Med 2005;11: 450-454
10. Cohen B, Dafni H, Meir G, et al. Ferritin as an endogenous MRI reporter for noninvasive imaging of gene expression in C6 glioma tumors. Neoplasia 2005;7:109-117
11. Cohen B, Ziv K, Plaks V, et al. MRI detection of transcriptional regulation of gene expression in transgenic mice. Nat Med 2007;13: 498-503.
12. Komeili A, Li Z, Newman D, Jensen G. Magnetosomes are cell membrane invaginations organized by the actin-like protein MamK. Science 2006;311:242-245
13. Stephens C. Bacterial cell biology: managing magnetosomes. Curr Biol 2006;16:R363-5.
14. Johnsen S, Lohmann KJ. Magnetoreception in animals. Phys Today 2008;6:29-35.
15. Ritz T, Thalau P, Phillips J, et al. Resonance effects indicate a radical-pair mechanism for avian magnetic compass. Nature 2004; 429:177-180
16. Walker M, Quinn T, Kirschvink J, Groot C. Production of single- domain magnetite throughout life by sockeye salmon, Oncorhynchus nerka. J Exp Biol 1988;140:51-63.
17. Kirschvink J, Kobayashi-Kirschvink A, Woodford B. Magnetite biomineralization in the human brain. Proc Natl Acad Sci U S A 1992;89:7683-7687
18. Hautot D, Pankhurst Q, Khan N, Dobson J. Preliminary evaluation of nanoscale biogenic magnetite in Alzheimer's disease brain tissue. Proc R Soc Lond B (Suppl) 2003;270:S62-4
19. Komeili A. Molecular mechanisms of magnetosome formation. Annu Rev Biochem 2007;76:1-27.
20. Schuler D. Molecular analysis of a subcellular compartment: the magnetosome membrane in Magnetospirillum gryphiswaldense. Arch Microbiol 2004;181:1-7. (Pubitemid 38161230)
21. Matsunaga T, Nakamura C, Burgess J, Sode K. Gene transfer in magnetic bacteria: transposon mutagenesis and cloning ofgenomic DNA fragments required for magnetosome synthesis. J Bacteriol 1992;174:2748-2753
22. Nakamura C, Burgess J, Sode K, Matsunaga T. An iron-regulated gene, magA, encoding an iron transport protein of Magnetospirillum sp. strain AMB-1. J Biol Chem 1995;270: 28392-28396
23. Nakamura C, Kikuchi T, Burgess J, Matsunaga T. Iron-regulated expression and membrane localization of the magA protein in Magnetospirillum. sp. strain. AMB-1. J. Biochem. 1995;118: 23-27
24. Zurkiya O, Chan A, Hu X. MagA is sufficient for producing magnetic nanoparticles in mammalian cells, making it an MRI reporter. Magn Reson Med 2008;59:1225-1231
25. Foster-Gareau P, Heyn C, Alejski A, Rutt B. Imaging single mammalian cells with a 1.5 T clinical MRI scanner. Magn Reson Med 2003;49:968-971
26. Smith PK, Krohn RI, Hermanson GT, et al. Measurement of protein using bicinchoninic acid. Anal Biochem 1985;150:76-85.
27. Denizot F, Lang R. Rapid colorimetric assay for cell growth and survival. Modifications to the tetrazolium dye procedure giving improved sensitivity and reliability. J Immunol Methods 1986;89: 271-277
28. McGirr R, Ejbick C, Carter D, et al. Glucose dependence of the regulated secretory pathway in α TC1-6 cells. Endocrinology 2005; 146:4514-4523
29. Goldhawk D, Carter D, Hobkirk R. Microscopic and biochemical analysis of the viability and permeability of guinea pig amnion and chorion laeve in vitro. J Exp Zool 1996;275:383-397
30. Belton M, Commerford K, Hall J, et al. Real-time measurement of cytosolic free calcium concentration in HL-60 cells during static magnetic field exposure and activation by ATP. Bioelectro-magnetics 2008;29:439-46. 31. Cunningham C, Arai T, Yang P, et al. Positive contrast magnetic resonance imaging of cells labeled with magnetic nanoparticles. Magn Reson Med 2005;53:999-1005.
31. Baraibar M, Barbeito A, Muhoberac B, Vidal R. Iron-mediated aggregation and a localized structural change characterize ferritin from a mutant light chain polypeptide that causes neurodegenera- tion. J Biol Chem 2008;283:31679-31689
32. Zhang A-S, Enns C. Iron homeostasis: recently identified proteins provide insight into novel control mechanisms. J Biol Chem 2009; 284:711-715
33. Bazylinski D, Frankel R. Magnetosome formation in prokaryotes. Nat Rev Microbiol 2004;2:217-230