-
1
-
-
33244488712
-
Making progress on the natural history of multiple sclerosis
-
DOI 10.1093/brain/awl034
-
Compston A. Making progress on the natural history of multiple sclerosis. Brain 2006; 129: 561-563 (Pubitemid 43278219)
-
(2006)
Brain
, vol.129
, Issue.3
, pp. 561-563
-
-
Compston, A.1
-
2
-
-
56549105235
-
Disease-modifying agents for multiple sclerosis: Recent advances and future prospects
-
Menge T, Weber MS, Hemmer B, Kieseier BC, Von Büdingen HC, Warnke C, et al. Disease-modifying agents for multiple sclerosis: recent advances and future prospects. Drugs 2008; 68: 2444-2468
-
(2008)
Drugs
, vol.68
, pp. 2444-2468
-
-
Menge, T.1
Weber, M.S.2
Hemmer, B.3
Kieseier, B.C.4
Von Büdingen, H.C.5
Warnke, C.6
-
3
-
-
33644607018
-
Multiple sclerosis - The plaque and its pathogenesis
-
Frohman EM, Racke MK, Raine CS. Multiple sclerosis - the plaque and its pathogenesis. N Engl J Med 2006; 354: 942-955
-
(2006)
N Engl J Med
, vol.354
, pp. 942-955
-
-
Frohman, E.M.1
Racke, M.K.2
Raine, C.S.3
-
4
-
-
0030882355
-
Humanization of a mouse antibody against human alpha-4 integrin: A potential therapeutic for the treatment of multiple sclerosis
-
Leger OJ, Yednock TA, Tanner L, Horner HC, Hines DK, Keen S, et al. Humanization of a mouse antibody against human alpha-4 integrin: a potential therapeutic for the treatment of multiple sclerosis. Hum Antibodies 1997; 8: 3-16. (Pubitemid 27397156)
-
(1997)
Human Antibodies
, vol.8
, Issue.1
, pp. 3-16
-
-
Leger, O.J.P.1
Yednock, T.A.2
Tanner, L.3
Horner, H.C.4
Hines, D.K.5
Keen, S.6
Saldanha, J.7
Jones, S.T.8
Fritz, L.C.9
Bendig, M.M.10
-
5
-
-
34247854822
-
Pharmacological properties, toxicology and scientific rationale for the use of natalizumab (Tysabri) in inflammatory diseases
-
DOI 10.1111/j.1527-3458.2007.00003.x
-
Stüve O, Bennet JL. Pharmacological properties, toxicology and scientific rationale for the use of natalizumab (Tysabri) in inflammatory diseases. CNS Drugs Rev 2007; 13: 79-95. (Pubitemid 46697841)
-
(2007)
CNS Drug Reviews
, vol.13
, Issue.1
, pp. 79-95
-
-
Stuve, O.1
Bennett, J.L.2
-
6
-
-
37149001297
-
Natalizumab en el tratamiento de la esclerosis múltiple
-
Horga A, Horga de la Parte JF. Natalizumab en el tratamiento de la esclerosis múltiple. Rev Neurol 2007; 45: 293-303.
-
(2007)
Rev Neurol
, vol.45
, pp. 293-303
-
-
Horga, A.1
Horga De La Parte, J.F.2
-
7
-
-
0031802697
-
Osteopontin is a ligand for the alpha4beta1 integrin
-
Bayless KJ, Meininger GA, Scholtz JM, Davis GE. Osteopontin is a ligand for the alpha4beta1 integrin. J Cell Sci 1998; 111 (Pt 9): 1165-1174
-
(1998)
J Cell Sci
, vol.111
, Issue.PART 9
, pp. 1165-1174
-
-
Bayless, K.J.1
Meininger, G.A.2
Scholtz, J.M.3
Davis, G.E.4
-
8
-
-
0028173015
-
The pathophysiologic role of alpha4 integrins in vivo
-
Lobb RR, Hemler ME. The pathophysiologic role of alpha 4 integrins in vivo. J Clin Invest 1994; 94: 1722-1728 (Pubitemid 2150008)
-
(1994)
Journal of Clinical Investigation
, vol.94
, Issue.5
, pp. 1722-1728
-
-
Lobb, R.R.1
Hemler, M.E.2
-
9
-
-
3042739652
-
4-integrin antagonist selective adhesion molecule inhibitors for MS
-
DOI 10.1586/14737175.4.4.571
-
Rudick RA, Sandrock A. Natalizumab: alpha 4-integrin antagonist selective adhesion molecule inhibitors for MS. Expert Rev Neurother 2004; 4: 571-580 (Pubitemid 38890585)
-
(2004)
Expert Review of Neurotherapeutics
, vol.4
, Issue.4
, pp. 571-580
-
-
Rudick, R.A.1
Sandrock, A.2
-
10
-
-
0033596831
-
A safety and pharmacokinetic study of intravenous natalizumab in patients with MS
-
Sheremata WA, Vollmer TL, Stone LA, Willmer-Hulme AJ, Koller M. A safety and pharmacokinetic study of intravenous natalizumab in patients with MS. Neurology 1999; 52: 1072-1074 (Pubitemid 29161624)
-
(1999)
Neurology
, vol.52
, Issue.5
, pp. 1072-1074
-
-
Sheremata, W.A.1
Vollmer, T.L.2
Stone, L.A.3
Willmer-Hulme, A.J.4
Koller, M.5
-
11
-
-
33646373639
-
Natalizumab: Immune effects and implications for therapy
-
DOI 10.1002/ana.20877
-
Hauser SL, Weiner HL. Natalizumab: immune effects and implications for therapy. Ann Neurol 2006; 59: 731-732 (Pubitemid 43673148)
-
(2006)
Annals of Neurology
, vol.59
, Issue.5
, pp. 731-732
-
-
Hauser, S.L.1
Weiner, H.L.2
-
12
-
-
0037413467
-
A controlled trial of natalizumab for relapsing multiple sclerosis
-
DOI 10.1056/NEJMoa020696
-
Miller DH, Khan OA, Sheremata WA, Blumhardt LD, Rice GP, Libinati MA, et al. A controlled trial of natalizumab for relapsing multiple sclerosis. N Engl J Med 2003; 348: 15-23. (Pubitemid 36026342)
-
(2003)
New England Journal of Medicine
, vol.348
, Issue.1
, pp. 15-23
-
-
Miller, D.H.1
Khan, O.A.2
Sheremata, W.A.3
Blumhardt, L.D.4
Rice, G.P.A.5
Libonati, M.A.6
Willmer-Hulme, A.J.7
Dalton, C.M.8
Miszkiel, K.A.9
O'Connor, P.W.10
-
13
-
-
33644584352
-
A randomized, placebo-controlled trial of natalizumab for relapsing multiple sclerosis
-
DOI 10.1056/NEJMoa044397
-
Polman CH, O'Connor PW, Havrdova E, Hutchinson M, Kappos L, Miller DH, et al. A randomised, placebo-controlled trial of natalizumab for relapsing multiple sclerosis. N Engl J Med 2006; 354: 899-910. (Pubitemid 43313657)
-
(2006)
New England Journal of Medicine
, vol.354
, Issue.9
, pp. 899-910
-
-
Polman, C.H.1
O'Connor, P.W.2
Havrdova, E.3
Hutchinson, M.4
Kappos, L.5
Miller, D.H.6
Phillips, J.T.7
Lublin, F.D.8
Giovannoni, G.9
Wajgt, A.10
Toal, M.11
Lynn, F.12
Panzara, M.A.13
Sandrock, A.W.14
-
14
-
-
33644608613
-
Natalizumab plus interferon beta-1a for relapsing multiple sclerosis
-
DOI 10.1056/NEJMoa044396
-
Rudick RA, Stuart WH, Calabresi PA, Confavreux C, Galetta SL, Radue EW, et al. Natalizumab plus interferon beta-1 a for relapsing multiple sclerosis. N Engl J Med 2006; 354: 911-923 (Pubitemid 43313658)
-
(2006)
New England Journal of Medicine
, vol.354
, Issue.9
, pp. 911-923
-
-
Rudick, R.A.1
Stuart, W.H.2
Calabresi, P.A.3
Confavreux, C.4
Galetta, S.L.5
Radue, E.-W.6
Lublin, F.D.7
Weinstock-Guttman, B.8
Wynn, D.R.9
Lynn, F.10
Panzara, M.A.11
Sandrock, A.W.12
-
15
-
-
70349300898
-
-
Efficacy and safety of natalizumab in the STRATA study. Poster 06.127
-
O'Connor P, Polman C, Goodman A, Kappos L, Lublin F, Rudick R, et al. Efficacy and safety of natalizumab in the STRATA study. Poster 06.127. 61st Annual Meeting of the American Academy of Neurology. Seattle, Washington, 2009.
-
61st Annual Meeting of the American Academy of Neurology. Seattle, Washington, 2009
-
-
O'Connor, P.1
Polman, C.2
Goodman, A.3
Kappos, L.4
Lublin, F.5
Rudick, R.6
-
16
-
-
70349282537
-
Natalizumab in patients with relapsing multiple sclerosis: Updated utilization and safety results including TOUCH and TYGRIS
-
Presentation 11.005
-
Bozic C, Belcher G, Kim R, Hyde R, Lynn F, Kooijmans-Coutinho M, et al. Natalizumab in patients with relapsing multiple sclerosis: updated utilization and safety results including TOUCH and TYGRIS. Presentation 11.005. 61st Annual Meeting of the American Academy of Neurology. Seattle, Washington, 2009.
-
61st Annual Meeting of the American Academy of Neurology. Seattle, Washington, 2009
-
-
Bozic, C.1
Belcher, G.2
Kim, R.3
Hyde, R.4
Lynn, F.5
Kooijmans-Coutinho, M.6
-
17
-
-
84942511463
-
-
Biogen Idec [01.07.2009]
-
Biogen Idec. TYSABRI Update. URL: http://phx.corporate-ir.net/External. File?item=UGFyZW50SUQ9MTEwODd8Q2hpbGRJRD0tMXxUeXBlPTM=&t=1. [01.07.2009].
-
TYSABRI Update
-
-
-
18
-
-
43549089971
-
Allergic and nonallergic delayed infusion reactions during natalizumab therapy
-
DOI 10.1001/archneur.65.5.656
-
Hellwig K, Schimrigk S, Fischer M, Haghikia A, Muller T, Chan A, et al. Allergic and nonallergic delayed infusion reactions during natalizumab therapy. Arch Neurol 2008; 65: 656-658 (Pubitemid 351679662)
-
(2008)
Archives of Neurology
, vol.65
, Issue.5
, pp. 656-658
-
-
Hellwig, K.1
Schimrigk, S.2
Fischer, M.3
Haghikia, A.4
Muller, T.5
Chan, A.6
Gold, R.7
-
19
-
-
33746825429
-
Progressive multifocal leukoencephalopathy revisited: Has the disease outgrown its name?
-
Koralnik IJ. Progressive multifocal leukoencephalopathy revisited: has the disease outgrown its name? Ann Neurol 2006; 60: 162-173
-
(2006)
Ann Neurol
, vol.60
, pp. 162-173
-
-
Koralnik, I.J.1
-
21
-
-
0036891078
-
Traffic of JC virus from sites of initial infection to the brain: The path to progressive multifocal leukoencephalopathy
-
Sabath, BF, Major EO. Traffic of JC virus from sites of initial infection to the brain: the path to progressive multifocal leukoencephalopathy. J Infect Dis 2002; 186 (Suppl 2): S180-6.
-
(2002)
J Infect Dis
, vol.186
, Issue.SUPPL. 2
-
-
Sabath, B.F.1
Major, E.O.2
-
22
-
-
0026801213
-
Evidence of human polyomavirus BK and JC infection in normal brain tissue
-
Elsner C, Dorries K. Evidence of human polyomavirus BK and JC infection in normal brain tissue. Virology 1992; 191: 72-80.
-
(1992)
Virology
, vol.191
, pp. 72-80
-
-
Elsner, C.1
Dorries, K.2
-
23
-
-
33745299246
-
Infectious complications associated with alemtuzumab use for lymphoproliferative disorders
-
DOI 10.1086/504811
-
Martin SI, Marty FM, Fiumara K, Treon SP, Gribben JG, Baden LR. Infectious complications associated with alemtuzumab use for lympho-proliferative disorders. Clin Infect Dis 2006; 43: 16-24. (Pubitemid 43939071)
-
(2006)
Clinical Infectious Diseases
, vol.43
, Issue.1
, pp. 16-24
-
-
Martin, S.I.1
Marty, F.M.2
Fiumara, K.3
Treon, S.P.4
Gribben, J.G.5
Baden, L.R.6
-
24
-
-
0037413240
-
4 integrins as therapeutic targets in autoimmune disease
-
DOI 10.1056/NEJMe020157
-
Von Andrian UH, Engelhardt, B. Alpha4 integrins as therapeutic targets in autoimmune disease. N Engl J Med 2003; 348: 68-72. (Pubitemid 36026351)
-
(2003)
New England Journal of Medicine
, vol.348
, Issue.1
, pp. 68-72
-
-
Von Andrian, U.H.1
Engelhardt, B.2
-
25
-
-
22844445230
-
Progressive multifocal leukoencephalopathy in a patient treated with natalizumab
-
DOI 10.1056/NEJMoa051847
-
Langer-Gould A, Atlas SW, Green AJ, Bollen AW, Pelletier D. Progressive multifocal leukoencephalopathy in a patient treated with natalizumab. N Engl J Med 2005; 353: 375-381 (Pubitemid 41132342)
-
(2005)
New England Journal of Medicine
, vol.353
, Issue.4
, pp. 375-381
-
-
Langer-Gould, A.1
Atlas, S.W.2
Green, A.J.3
Bollen, A.W.4
Pelletier, D.5
-
26
-
-
34347226702
-
Expert opinion: Guidelines for the use of natalizumab in multiple sclerosis patients previously treated with immunomodulating therapies
-
DOI 10.1016/j.jneuroim.2007.04.006, PII S0165572807001282
-
Gold R, Jawad A, Miller DH, Henderson DC, Fassas A, Fierz W, et al. Expert opinion: guidelines for the use of natalizumab in multiple sclerosis patients previously treated with immunomodulating therapies. J Neuroimmunol 2007; 187: 156-158 (Pubitemid 47001540)
-
(2007)
Journal of Neuroimmunology
, vol.187
, Issue.1-2
, pp. 156-158
-
-
Gold, R.1
Jawad, A.2
Miller, D.H.3
Henderson, D.C.4
Fassas, A.5
Fierz, W.6
Hartung, H.P.7
-
27
-
-
17644428059
-
Progressive multifocal leukoencephalopathy in transplant recipients
-
DOI 10.1007/s00147-004-0779-3
-
Shitrit D, Lev N, Bar-Gil-Shitrit A, Kramer MR. Progressive multifocal leukoencephalopathy in transplant recipients. Transpl Int 2005; 17: 658-665 (Pubitemid 40558222)
-
(2005)
Transplant International
, vol.17
, Issue.11
, pp. 658-665
-
-
Shitrit, D.1
Lev, N.2
Bar-Gil-Shitrit, A.3
Kramer, M.R.4
-
28
-
-
33846969181
-
Potential risk of progressive multifocal leukoencephalopathy with natalizumab therapy: Possible interventions
-
DOI 10.1001/archneur.64.2.169
-
Stüve O, Marra CM, Cravens PD, Singh MP, Hu W, Lovett-Racke A, et al. Potential risk of progressive multifocal leukoencephalopathy with natalizumab therapy: possible interventions. Arch Neurol 2007; 64: 169-176 (Pubitemid 46256555)
-
(2007)
Archives of Neurology
, vol.64
, Issue.2
, pp. 169-176
-
-
Stuve, O.1
Marra, C.M.2
Cravens, P.D.3
Singh, M.P.4
Hu, W.5
Lovett-Racke, A.6
Monson, N.L.7
Phillips, J.T.8
Cohen Tervaert, J.W.9
Nash, R.A.10
Hartung, H.-P.11
Kieseier, B.C.12
Racke, M.M.13
Frohman, E.M.14
Hemmer, B.15
-
29
-
-
38949166754
-
Melanoma complicating treatment with natalizumab for multiple sclerosis [16]
-
Mullen JT, Vartanian TK, Atkins MB. Melanoma complicating treatment with natalizumab for multiple sclerosis. N Engl J Med 2008; 358: 647-648 (Pubitemid 351214309)
-
(2008)
New England Journal of Medicine
, vol.358
, Issue.6
, pp. 647-648
-
-
Mullen, J.T.1
Vartanian, T.K.2
Atkins, M.B.3
-
30
-
-
70349279447
-
-
The safety of natalizumab in patients with relapsing multiple. Update from TOUCH and TYGRIS. Poster P06.095
-
Bozic C, Belcher G, Kooijmans M, Kim R, Lynn F, Panzara MA. The safety of natalizumab in patients with relapsing multiple. Update from TOUCH and TYGRIS. Poster P06.095. 59th Annual Meeting of the American Academy of Neurology. Boston, Maryland, 2007.
-
59th Annual Meeting of the American Academy of Neurology. Boston, Maryland, 2007
-
-
Bozic, C.1
Belcher, G.2
Kooijmans, M.3
Kim, R.4
Lynn, F.5
Panzara, M.A.6
-
31
-
-
70349291582
-
-
30.12.2006
-
European Medicine Agency. URL: http://www.emea.europa.eu/humandocs/PDFs/ EPAR/ tysabri/H-603-en6.pdf. [30.12.2006].
-
-
-
-
32
-
-
34047272106
-
Natalizumab treatment for multiple sclerosis: Recommendations for patient selection and monitoring
-
DOI 10.1016/S1474-4422(07)70078-9, PII S1474442207700789
-
Kappos L, Bates D, Hartung HP, Havrdova E, Miller D, Polman CH, et al. Natalizumab treatment for multiple sclerosis: recommendations for patient selection and monitoring. Lancet Neurol 2007; 6: 431-441 (Pubitemid 46551850)
-
(2007)
Lancet Neurology
, vol.6
, Issue.5
, pp. 431-441
-
-
Kappos, L.1
Bates, D.2
Hartung, H.-P.3
Havrdova, E.4
Miller, D.5
Polman, C.H.6
Ravnborg, M.7
Hauser, S.L.8
Rudick, R.A.9
Weiner, H.L.10
O'Connor, P.W.11
King, J.12
Radue, E.W.13
Yousry, T.14
Major, E.O.15
Clifford, D.B.16
-
33
-
-
70349299346
-
-
Efficacy of natalizumab in multiple sclerosis patients with high disease activity: a Danish nationwide study. Poster 06.134
-
Oturai AB, Koch-Henriksen N, Petersen T, Jensen PEH, Sellebjerg F, Sorensen PS. Efficacy of natalizumab in multiple sclerosis patients with high disease activity: a Danish nationwide study. Poster 06.134. 61st Annual Meeting of the American Academy of Neurology. Seattle, Washington, 2009.
-
61st Annual Meeting of the American Academy of Neurology. Seattle, Washington, 2009
-
-
Oturai, A.B.1
Koch-Henriksen, N.2
Petersen, T.3
Jensen, P.E.H.4
Sellebjerg, F.5
Sorensen, P.S.6
-
34
-
-
70349287064
-
-
Natalizumab reduces clinical and MRI disease activity in second line treatment of relapsing remitting multiple sclerosis: results of a multicenter study. Poster 05.128
-
Putzki N, Yaldizli O, St. Mäurer M, Kuckert S, Cursiefen S, Tettenborn B, et al. Natalizumab reduces clinical and MRI disease activity in second line treatment of relapsing remitting multiple sclerosis: results of a multicenter study. Poster 05.128. 61st Annual Meeting of the American Academy of Neurology. Seattle, Washington, 2009.
-
61st Annual Meeting of the American Academy of Neurology. Seattle, Washington, 2009
-
-
Putzki, N.1
Yaldizli, O.2
St. Mäurer, M.3
Kuckert, S.4
Cursiefen, S.5
Tettenborn, B.6
-
35
-
-
70349285488
-
-
Effect of natalizumab on relapse outcomes in patients with relapsing MS who experience MRI activity during treatment. Poster 05.135
-
Bates D, Bartholome E, Pace A, Hyde R, Hotermans G. Effect of natalizumab on relapse outcomes in patients with relapsing MS who experience MRI activity during treatment. Poster 05.135. 61st Annual Meeting of the American Academy of Neurology. Seattle, Washington, 2009.
-
61st Annual Meeting of the American Academy of Neurology. Seattle, Washington, 2009
-
-
Bates, D.1
Bartholome, E.2
Pace, A.3
Hyde, R.4
Hotermans, G.5
-
36
-
-
70349291581
-
-
Natalizumab (Tysabri) promotes remyelination in patients with multiple sclerosis. A voxel-wise magnetization transfer imaging case-control study. Poster 03.071
-
Zivadinov R, Dwyer MG, Bergsland N, Hussein S, Cox J, Durfee J, et al. Natalizumab (Tysabri) promotes remyelination in patients with multiple sclerosis. A voxel-wise magnetization transfer imaging case-control study. Poster 03.071. 61st Annual Meeting of the American Academy of Neurology. Seattle, Washington, 2009.
-
61st Annual Meeting of the American Academy of Neurology. Seattle, Washington, 2009
-
-
Zivadinov, R.1
Dwyer, M.G.2
Bergsland, N.3
Hussein, S.4
Cox, J.5
Durfee, J.6
-
37
-
-
70349271684
-
-
Sustained improvement in physical disability with natalizumab in patients with relapsing multiple sclerosis. Poster 06.131
-
Munschauer F, Giovannoni G, Lublin F, O'Connor P, Phillips JT, Polman C. et al. Sustained improvement in physical disability with natalizumab in patients with relapsing multiple sclerosis. Poster 06.131. 61st Annual Meeting of the American Academy of Neurology. Seattle, Washington, 2009.
-
61st Annual Meeting of the American Academy of Neurology. Seattle, Washington, 2009
-
-
Munschauer, F.1
Giovannoni, G.2
Lublin, F.3
O'Connor, P.4
Phillips, J.T.5
Polman, C.6
|