-
1
-
-
0344432099
-
-
Lyon: International Agency for Research and Cancer (IARC)
-
Parkin DM, Whelan SL, Ferlay J, Teppo L, Thomas DB. Cancer incidence in five continents. Vol 8. Lyon: International Agency for Research and Cancer (IARC); 2002.
-
(2002)
Cancer Incidence in Five Continents
, vol.8
-
-
Parkin, D.M.1
Whelan, S.L.2
Ferlay, J.3
Teppo, L.4
Thomas, D.B.5
-
2
-
-
35648953299
-
Gefitinib-induced killing of NSCLC cell lines expressing mutant EGFR requires BIM and can be enhanced by BH3 mimetics
-
DOI 10.1371/journal.pmed.0040316
-
Cragg MS, Kuroda J, Puthalakath H, Huang DC, Strasser A. Gefitinib-induced killing of NSCLC cell lines expressing mutant EGFR requires BIM and can be enhanced by BH3 mimetics. PLoS Med 2007; 4: 1681-1689 (Pubitemid 350035457)
-
(2007)
PLoS Medicine
, vol.4
, Issue.10
, pp. 1681-1690
-
-
Cragg, M.S.1
Kuroda, J.2
Puthalakath, H.3
Huang, D.C.S.4
Strasser, A.5
-
3
-
-
21744460198
-
Antitumor effect of gefitinib ('Iressa') on esophageal squamous cell carcinoma cell lines in vitro and in vivo
-
DOI 10.1016/j.canlet.2004.12.025, PII S0304383504009978
-
Hara F, Aoe M, Doihara H, Taira N, Shien T, Takahashi H, et al. Antitumor effect of gefitinib ('Iressa') on esophageal squamous cell carcinoma cell lines in vitro and in vivo. Cancer Lett 2005; 226: 37-47. (Pubitemid 40943428)
-
(2005)
Cancer Letters
, vol.226
, Issue.1
, pp. 37-47
-
-
Hara, F.1
Aoe, M.2
Doihara, H.3
Taira, N.4
Shien, T.5
Takahashi, H.6
Yoshitomi, S.7
Tsukuda, K.8
Toyooka, S.9
Ohta, T.10
Shimizu, N.11
-
4
-
-
22044442973
-
Tyrosine kinases as targets for cancer therapy
-
DOI 10.1056/NEJMra044389
-
Krause DS, Van Etten RA. Tyrosine kinases as targets for cancer therapy. N Engl J Med 2005; 353: 172-187 (Pubitemid 41058349)
-
(2005)
New England Journal of Medicine
, vol.353
, Issue.2
, pp. 172-187
-
-
Krause, D.S.1
Van Etten, R.A.2
-
5
-
-
13844317894
-
EGFR mutation and resistance of non-small-cell lung cancer to gefitinib
-
DOI 10.1056/NEJMoa044238
-
Kobayashi S, Boggon TJ, Dayaram T, Janne PA, Kocher O, Meyerson M, et al. EGFR mutation and resistance of non-small-cell lung cancer to gefitinib. N Engl J Med 2005; 352: 786-792 (Pubitemid 40271173)
-
(2005)
New England Journal of Medicine
, vol.352
, Issue.8
, pp. 786-792
-
-
Kobayashi, S.1
Boggon, T.J.2
Dayaram, T.3
Janne, P.A.4
Kocher, O.5
Meyerson, M.6
Johnson, B.E.7
Eck, M.J.8
Tenen, D.G.9
Halmos, B.10
-
6
-
-
33745985181
-
A rapid, sensitive assay to detect EGFR mutation in small biopsy specimens from lung cancer
-
DOI 10.2353/jmoldx.2006.050104
-
Yatabe Y, Hida T, Horio Y, Kosaka T, Takahashi T, Mitsudomi T. A rapid, sensitive assay to detect EGFR mutation in small biopsy specimens from lung cancer. J Mol Diagn 2006; 8: 335-341 (Pubitemid 44063810)
-
(2006)
Journal of Molecular Diagnostics
, vol.8
, Issue.3
, pp. 335-341
-
-
Yatabe, Y.1
Hida, T.2
Horio, Y.3
Kosaka, T.4
Takahashi, T.5
Mitsudomi, T.6
-
7
-
-
0142055937
-
Efficacy of Gefitinib, an Inhibitor of the Epidermal Growth Factor Receptor Tyrosine Kinase, in Symptomatic Patients with Non-Small Cell Lung Cancer: A Randomized Trial
-
DOI 10.1001/jama.290.16.2149
-
Kris MG, Natale RB, Herbst RS, Lynch TJ Jr, Prager D, Belani CP, et al. Efficacy of gefitinib, an inhibitor of the epidermal growth factor receptor tyrosine kinase, in symptomatic patients with non-small cell lung cancer: a randomized trial. JAMA 2003; 290: 2149-2158 (Pubitemid 37432975)
-
(2003)
Journal of the American Medical Association
, vol.290
, Issue.16
, pp. 2149-2158
-
-
Kris, M.G.1
Natale, R.B.2
Herbst, R.S.3
Lynch Jr., T.J.4
Prager, D.5
Belani, C.P.6
Schiller, J.H.7
Kelly, K.8
Spiridonidis, H.9
Sandler, A.10
Albain, K.S.11
Cella, D.12
Wolf, M.K.13
Averbuch, S.D.14
Ochs, J.J.15
Kay, A.C.16
-
8
-
-
22044445517
-
Erlotinib in previously treated non-small-cell lung cancer
-
DOI 10.1056/NEJMoa050753
-
Shepherd FA, Rodrigues PJ, Ciuleanu T, Tan EH, Hirsh V, Thongprasert S, et al. Erlotinib in previously treated non-small-cell lung cancer. N Engl J Med 2005; 353: 123-132 (Pubitemid 41058344)
-
(2005)
New England Journal of Medicine
, vol.353
, Issue.2
, pp. 123-132
-
-
Shepherd, F.A.1
Pereira, J.R.2
Ciuleanu, T.3
Eng, H.T.4
Hirsh, V.5
Thongprasert, S.6
Campos, D.7
Maoleekoonpiroj, S.8
Smylie, M.9
Martins, R.10
Van Kooten, M.11
Dediu, M.12
Findlay, B.13
Tu, D.14
Johnston, D.15
Bezjak, A.16
Clark, G.17
Santabarbara, P.18
Seymour, L.19
-
9
-
-
2342471392
-
Activating Mutations in the Epidermal Growth Factor Receptor Underlying Responsiveness of Non-Small-Cell Lung Cancer to Gefitinib
-
DOI 10.1056/NEJMoa040938
-
Lynch TJ, Bell DW, Sordella R, Gurubhagavatula S, Okimoto RA, Brannigan BW, et al. Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib. N Engl J Med 2004; 350: 2129-2139 (Pubitemid 38637993)
-
(2004)
New England Journal of Medicine
, vol.350
, Issue.21
, pp. 2129-2139
-
-
Lynch, T.J.1
Bell, D.W.2
Sordella, R.3
Gurubhagavatula, S.4
Okimoto, R.A.5
Brannigan, B.W.6
Harris, P.L.7
Haserlat, S.M.8
Supko, J.G.9
Haluska, F.G.10
Louis, D.N.11
Christiani, D.C.12
Settleman, J.13
Haber, D.A.14
-
10
-
-
2342624080
-
EGFR mutations in lung, cancer: Correlation with clinical response to gefitinib therapy
-
DOI 10.1126/science.1099314
-
Paez JG, Janne PA, Lee JC, Tracy S, Greulich H, Gabriel S, et al. EGFR mutations in lung cancer: correlation with clinical response to gefitinib therapy. Science 2004; 304: 1497-1500 (Pubitemid 38720929)
-
(2004)
Science
, vol.304
, Issue.5676
, pp. 1497-1500
-
-
Paez, J.G.1
Janne, P.A.2
Lee, J.C.3
Tracy, S.4
Greulich, H.5
Gabriel, S.6
Herman, P.7
Kaye, F.J.8
Lindeman, N.9
Boggon, T.J.10
Naoki, K.11
Sasaki, H.12
Fujii, Y.13
Eck, M.J.14
Sellers, W.R.15
Johnson, B.E.16
Meyerson, M.17
-
11
-
-
22044453790
-
Erlotinib in lung cancer - Molecular and clinical predictors of outcome
-
DOI 10.1056/NEJMoa050736
-
Tsao MS, Sakurada A, Cutz JC, Zhu CQ, Kamel- Reid S, Squire J, et al. Erlotinib in lung cancer - molecular and clinical predictors of outcome. N Engl J Med 2005; 353: 133-144 (Pubitemid 41058345)
-
(2005)
New England Journal of Medicine
, vol.353
, Issue.2
, pp. 133-144
-
-
Tsao, M.-S.1
Sakurada, A.2
Cutz, J.-C.3
Zhu, C.-Q.4
Kamel-Reid, S.5
Squire, J.6
Lorimer, I.7
Zhang, T.8
Liu, N.9
Daneshmand, M.10
Marrano, P.11
Da Cunha Santos, G.12
Lagarde, A.13
Richardson, F.14
Seymour, L.15
Whitehead, M.16
Ding, K.17
Pater, J.18
Shepherd, F.A.19
-
12
-
-
20444498630
-
Epidermal growth factor receptor gene and protein and gefitinib sensitivity in non-small-cell lung cancer
-
DOI 10.1093/jnci/dji112
-
Cappuzzo F, Hirsch FR, Rossi E, Bartolini S, Ceresoli GL, Bemis L, et al. Epidermal growth factor receptor gene and protein and gefitinib sensitivity in non-small-cell lung cancer. J Natl Cancer Inst 2005; 97: 643-655 (Pubitemid 40812628)
-
(2005)
Journal of the National Cancer Institute
, vol.97
, Issue.9
, pp. 643-655
-
-
Cappuzzo, F.1
Hirsch, F.R.2
Rossi, E.3
Bartolini, S.4
Ceresoli, G.L.5
Bemis, L.6
Haney, J.7
Witta, S.8
Danenberg, K.9
Domenichini, I.10
Ludovini, V.11
Magrini, E.12
Gregorc, V.13
Doglioni, C.14
Sidoni, A.15
Tonato, M.16
Franklin, W.A.17
Crino, L.18
Bunn Jr., P.A.19
Varella-Garcia, M.20
more..
-
13
-
-
33745964591
-
Epidermal growth factor receptor tyrosine kinase inhibitors in lung cancer: Impact of primary or secondary mutations
-
Sakurada A, Shepherd FA, Tsao MS. Epidermal growth factor receptor tyrosine kinase inhibitors in lung cancer: impact of primary or secondary mutations. Clin Lung Cancer 2006; 7(Suppl 4): S138-44. (Pubitemid 44056782)
-
(2006)
Clinical Lung Cancer
, vol.7
, Issue.SUPPL. 4
-
-
Sakurada, A.1
Shepherd, F.A.2
Tsao, M.-S.3
-
14
-
-
13244298108
-
Epidermal growth factor receptor and cyclin D1 are independently amplified and overexpressed in esophageal squamous cell carcinoma
-
DOI 10.1007/s00432-004-0610-7
-
Sunpaweravong P, Sunpaweravong S, Puttawibul P, Mitarnun W, Zeng C, Baron AE, et al. Epidermal growth factor receptor and cyclin D1 are independently amplified and overexpressed in esophageal squamous cell carcinoma. J Cancer Res Clin Oncol 2005; 131: 111-119 (Pubitemid 40192936)
-
(2005)
Journal of Cancer Research and Clinical Oncology
, vol.131
, Issue.2
, pp. 111-119
-
-
Sunpaweravong, P.1
Sunpaweravong, S.2
Puttawibul, P.3
Mitarnun, W.4
Zeng, C.5
Baron, A.E.6
Franklin, W.7
Said, S.8
Varella-Garcia, M.9
-
15
-
-
33845647652
-
Mutation profile of EGFR gene detected by denaturing high-performance liquid chromatography in Japanese lung cancer patients
-
DOI 10.1007/s00432-006-0144-2
-
Sueoka N, Sato A, Eguchi H, Komiya K, Sakuragi T, Mitsuoka M, et al. Mutation profile of EGFR gene detected by denaturing high-performance liquid chromatography in Japanese lung cancer patients. J Cancer Res Clin Oncol 2007; 133: 93-102. (Pubitemid 44950241)
-
(2007)
Journal of Cancer Research and Clinical Oncology
, vol.133
, Issue.2
, pp. 93-102
-
-
Sueoka, N.1
Sato, A.2
Eguchi, H.3
Komiya, K.4
Sakuragi, T.5
Mitsuoka, M.6
Satoh, T.7
Hayashi, S.8
Nakachi, K.9
Sueoka, E.10
-
16
-
-
38349120527
-
EGFR mutations and EGFR tyrosine kinase inhibition in non-small cell lung cancer
-
Miller VA. EGFR mutations and EGFR tyrosine kinase inhibition in non-small cell lung cancer. Semin Oncol Nurs 2008; 24: 27-33.
-
(2008)
Semin Oncol Nurs
, vol.24
, pp. 27-33
-
-
Miller, V.A.1
-
17
-
-
31844432805
-
EGFR protein overexpression and gene amplification in squamous cell carcinomas of the esophagus
-
DOI 10.1002/ijc.21454
-
Hanawa M, Suzuki S, Dobashi Y, Yamane T, Kono K, Enomoto N, et al. EGFR protein overexpression and gene amplification in squamous cell carcinomas of the esophagus. Int J Cancer 2006; 118: 1173-1180 (Pubitemid 43185604)
-
(2006)
International Journal of Cancer
, vol.118
, Issue.5
, pp. 1173-1180
-
-
Hanawa, M.1
Suzuki, S.2
Dobashi, Y.3
Yamane, T.4
Kono, K.5
Enomoto, N.6
Ooi, A.7
-
18
-
-
33645734242
-
Predictive factors for outcome in a phase II study of gefitinib in second-line treatment of advanced esophageal cancer patients
-
DOI 10.1200/JCO.2005.03.4900
-
Janmaat ML, Gallegos-Ruiz MI, Rodriguez JA, Meijer GA, Vervenne WL, Richel DJ, et al. Predictive factors for outcome in a phase II study of gefitinib in second-line treatment of advanced esophageal cancer patients. J Clin Oncol 2006; 24: 1612-1619 (Pubitemid 46638785)
-
(2006)
Journal of Clinical Oncology
, vol.24
, Issue.10
, pp. 1612-1619
-
-
Janmaat, M.L.1
Gallegos-Ruiz, M.I.2
Rodriguez, J.A.3
Meijer, G.A.4
Vervenne, W.L.5
Richel, D.J.6
Van Groeningen, C.7
Giaccone, G.8
-
19
-
-
33750618860
-
Phase II trial of erlotinib in gastroesophageal junction and gastric adenocarcinomas: SWOG 0127
-
DOI 10.1200/JCO.2006.07.1316
-
Dragovich T, McCoy S, Fenoglio-Preiser CM, Wang J, Benedetti JK, Baker AF, et al. Phase II trial of erlotinib in gastroesophageal junction and gastric adenocarcinomas: SWOG 0127. J Clin Oncol 2006; 24: 4922-4927 (Pubitemid 46630921)
-
(2006)
Journal of Clinical Oncology
, vol.24
, Issue.30
, pp. 4922-4927
-
-
Dragovich, T.1
McCoy, S.2
Fenoglio-Preiser, C.M.3
Wang, J.4
Benedetti, J.K.5
Baker, A.F.6
Hackett, C.B.7
Urba, S.G.8
Zaner, K.S.9
Blanke, C.D.10
Abbruzzese, J.L.11
-
20
-
-
27744606737
-
Molecular determinants of the response of glioblastomas to EGFR kinase inhibitors
-
DOI 10.1056/NEJMoa051918
-
Mellinghoff IK, Wang MY, Vivanco I, Haas-Kogan DA, Zhu S, Dia EQ, et al. Molecular determinants of the response of glioblastomas to EGFR kinase inhibitors. N Engl J Med 2005; 353: 2012-2024 (Pubitemid 41609094)
-
(2005)
New England Journal of Medicine
, vol.353
, Issue.19
, pp. 2012-2024
-
-
Mellinghoff, I.K.1
Wang, M.Y.2
Vivanco, I.3
Haas-Kogan, D.A.4
Zhu, S.5
Dia, E.Q.6
Lu, K.V.7
Yoshimoto, K.8
Huang, J.H.Y.9
Chute, D.J.10
Riggs, B.L.11
Horvath, S.12
Liau, L.M.13
Cavenee, W.K.14
Nagesh Rao, P.15
Beroukhim, R.16
Peck, T.C.17
Lee, J.C.18
Sellers, W.R.19
Stokoe, D.20
Prados, M.21
Cloughesy, T.F.22
Sawyers, C.L.23
Mischel, P.S.24
more..
-
21
-
-
19944422060
-
Somatic mutations of EGFR in colorectal cancers and glioblastomas [6]
-
DOI 10.1056/NEJM200412303512724
-
Barber TD, Vogelstein B, Kinzler KW, Velculescu VE. Somatic mutations of EGFR in colorectal cancers and glioblastomas. N Engl J Med 2004; 351: 2883. (Pubitemid 40051921)
-
(2004)
New England Journal of Medicine
, vol.351
, Issue.27
, pp. 2883
-
-
Barber, T.D.1
Vogelstein, B.2
Kinzler, K.W.3
Velculescu, V.E.4
-
22
-
-
4644238311
-
EGFR mutations and sensitivity to gefitinib
-
Rich JN, Rasheed BK, Yan H. EGFR mutations and sensitivity to gefitinib. N Engl J Med 2004; 351: 1260-1261
-
(2004)
N Engl J Med
, vol.351
, pp. 1260-1261
-
-
Rich, J.N.1
Rasheed, B.K.2
Yan, H.3
|