Fibronectin fragments mediate matrix metalloproteinase upregulation and cartilage damage through proline rich tyrosine kinase 2, c-src, NF-κB and protein kinase Cδ

Osteoarthritis and Cartilage

Volumn 17, Issue 10, 2009, Pages 1385-1392

  Ding, L ^a   Guo, D ^a   Homandberg, G A ^a  

^a UNIVERSITY OF NORTH DAKOTA SCHOOL OF MEDICINE AND HEALTH SCIENCES   (United States)

Author keywords

Cartilage; Cartilage damage; Chondrocytes; Fibronectin; Fibronectin fragments; Intracellular signaling; Kinases; Matrix metalloproteinases

Indexed keywords

COLLAGENASE 3; FIBRONECTIN; FOCAL ADHESION KINASE 2; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MATRIX METALLOPROTEINASE; PHOSPHOTRANSFERASE INHIBITOR; PROTEIN KINASE C DELTA; PROTEIN TYROSINE KINASE; PROTEOGLYCAN; STROMELYSIN;

AMINO TERMINAL SEQUENCE; ANIMAL CELL; ANIMAL CELL CULTURE; ARTICLE; CARTILAGE CELL; CARTILAGE INJURY; CELL LYSATE; CONFOCAL MICROSCOPY; CONTROLLED STUDY; COW; ENZYME ACTIVATION; ENZYME LOCALIZATION; ENZYME PHOSPHORYLATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEPLETION; UPREGULATION;

ANIMALS; CARTILAGE; CATTLE; CELLS, CULTURED; CHONDROCYTES; FIBRONECTINS; FOCAL ADHESION KINASE 2; MATRIX METALLOPROTEINASES; NF-KAPPA B; PROTEIN KINASE C-DELTA; PROTEIN KINASES; PROTEOGLYCANS; UP-REGULATION;

EID: 70349260481     PISSN: 10634584     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.joca.2009.03.024     Document Type: Article

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