A rapid polymerisation process realizing 3D biocompatible structures in a microfluidic channel suitable for genetic analysis

Sensors and Actuators, B: Chemical

Volumn 142, Issue 1, 2009, Pages 383-388

  Brennan, D ^a   Dillmore, S ^a   Moore, E ^a   Galvin, P ^a  

^a UNIVERSITY COLLEGE CORK   (Ireland)

Author keywords

DNA hybridisation; Eosin Y; Microfluidics; Photo initiation

Indexed keywords

3D STRUCTURE; ANALYTES; BONDING TECHNIQUES; CHANNEL SURFACE; DIRECT WRITE; DNA HYBRIDISATION; DNA MOLECULES; DNA PROBE; EOSIN-Y; FLUIDIC ALIGNMENT; FLUIDIC SYSTEMS; GEL STRUCTURES; GENETIC ANALYSIS; HIGH TEMPERATURE; HYBRIDISATION; HYDROGEL STRUCTURE; IMMOBILISATION; MICRO FLUIDIC SYSTEM; MICROFLUIDIC CHANNEL; PHOTO-INITIATION; POLYMERISATION; PREPOLYMERS; SURFACE FUNCTIONALISATION; SURFACE PROBES; TIME-CONSUMING TASKS; UV CURED;

ALIGNMENT; BIOMOLECULES; DNA; ETHYLENE; FLUIDIC DEVICES; GENES; MONOMERS; NUCLEIC ACIDS; POLYETHYLENE GLYCOLS; POLYMERIZATION; PROBES; SILICONES; SURFACES; THREE DIMENSIONAL;

MICROFLUIDICS;

EID: 70349247690     PISSN: 09254005     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.snb.2009.07.027     Document Type: Article

References (21)

1. Brennan D., Lambkin P., Moore E.J., and Galvin P. An integrated optofluidic platform for DNA hybridisation and detection. IEEE Sensors Journal 5 (2008) 536-542
2. Vollmer F., Arnold S., Braun D., Teraoko I., and Libchaber A. Multiplexed DNA quantification by spectroscopic shift of two microsphere cavities. Biophysical Journal 85 (2003) 1974-1979
3. Yang G., White I.M., and Fan X. An optofluidic ring resonator biosensor for detection of organophosphorus pesticides. Sensors and Actuators B 133 (2008) 105-112
4. Mandal S., and Erickson D. Nanoscale optofluidic sensor arrays. Optics Express 16 (2008) 1623-1631
5. Berney H., and Oliver K. Dual polarization interferometry size and density characterisation of DNA immobilisation and hybridization. Biosensors and Bioelectronics 21 (2005) 618-626
6. Lillis B., Manning M., Berney H., Hurley E., Mathewson A., and Sheehan M. Dual polarisation interferometry characterisation of DNA immobilisation and hybridisation detection on a silanised support. Biosensors and Bioelectronics 21 (2006) 1459-1467
7. www.affymetrix.com
8. www.nimblegen.com
9. Qiu B., Stefanos S., Ma J., Lalloo A., Perry B.A., Leibowitz M.J., Sinko P.J., and Stein S. A hydrogel prepared by in situ cross-linking of a thiol containing poly(ethylene glycol)-based copolymer: a new biomaterial for protein drug delivery. Biomaterials 25 (2004) 11-18
10. Quick D.J., and Anseth K.S. DNA delivery from photocrosslinked PEG hydrogels: encapsulation efficiency, release profiles and DNA quality. Journal of Controlled Release 2 (2004) 341-351
11. Underhill G., Chen A., Albrect D., and Bhatia S. Assessment of hepatocellular function with PEG hydrogels. Biomaterials 28 (2007) 256-270
12. Hahn M., Lakeshia J.T., Moon J.J., Maude C., Ruffino K.A., and West J. Hololithographic patterning of polyethylene glycol hydrogels. Biomaterials 27 (2006) 2519-2524
13. Kizilel S., Sawardecker E., Teymour F., and Perez-Luna V.H. Sequential formation of covalently bonded hydrogel multilayers through surface initiated photopolymerisation. Biomaterials 27 (2006) 1209-1215
14. Chen F., Zhoa Y.M., Sun H., Toa J., Wang Q., Zhou W., Wu Z., and Yan J. Novel glycidyl methacrylated dextran/gelatine hydrogel scaffolds containing microspheres loaded with bone morphogenetic proteins; formulation and characteristics. Journal of Controlled Release 118 (2007) 65-77
15. N. Lee, Y. Kyung, J. Park, H.G. Park, On-chip colorimetric biosensor based on polydiacetylene (PDA) embedded in photopolymerised poly(ethylene glycol) diacrylate (PEG-DA) Hydrogel, Biochemical Engineering Journal, Available Online 11 July 2005.
16. Gurevitch D., Fan X., Pricher T.J., Matsumoto S., Roycroft P., Tsinberg P., Falcovitz H., and Hahn S. A novel three dimensional hydrogel based microarray platform. Journal of the Association for Laboratory Automation 4 (2001) 87-91
17. Cheung Y.K., Gillette B., Zhong M., Ramcharan S., and Sia S.K. Direct patterning of composite biocompatible microstructures using microfluidics. Lab Chip 7 (2007) 574-579
18. Heo J., and Crooks R.M. Microfluidic biosensor based on an array of hydrogel entrapped enzymes. Analytical Chemistry 77 (2005) 6843-6851
19. Olsen K.G., Ross D.J., and Talov M.J. Immobilisation of DNA hydrogel plugs in microfluidic channels. Analytical Chemistry 74 (2002) 1436-1441
20. Zangmeister R.A., and Tarlov M.J. UV graft polymerisation of polyacrylamide hydrogel plugs in microfluidic channels. Langmuir 19 (2003) 6901-6904
21. Zangmeister R.A., and Tarlov M.J. DNA displacement assay integrated into microfluidic channels. Analytical Chemistry 76 (2004) 3655-3659