Amino acetate functionalized Schiff base organotin(IV) complexes as anticancer drugs: Synthesis, structural characterization, and in vitro cytotoxicity studies

Investigational New Drugs

Volumn 27, Issue 5, 2009, Pages 419-431

  Basu Baul, Tushar S ^a   Basu, Smita ^a   De Vos, Dick ^b   Linden, Anthony ^c  

^a NORTH EASTERN HILL UNIVERSITY   (India)

^b TEVA Pharmachemie   (Netherlands)

^c UNIVERSITY OF ZURICH   (Switzerland)

Author keywords

Amino acetate functionalized Schiff bases; Anti cancer drugs; Cell lines; NMR; Organotin(IV); Potassium 2 (2Z) (3 hydroxy 1 methyl 2 butenylidene) amino 4 methyl pentanoate; Potassium 2 (E) 1 (2 hydroxyphenyl)alkylidene amino 4 methyl pentanoates

Indexed keywords

ANTINEOPLASTIC AGENT; CISPLATIN; DOXORUBICIN; ETOPOSIDE; FLUOROURACIL; ORGANOTIN COMPOUND; POTASSIUM 2 [((3 HYDROXY 1 METHYL 2 BUTENYLIDENE)AMINO] 4 METHOXY PENTANOATE; POTASSIUM 2 [(1 (2 HYDROXYPHENYL)ALKYLIDENE)AMINO] 4 METHYL PENTANOATE; SCHIFF BASE; TRIPHENYLTIN; UNCLASSIFIED DRUG;

ARTICLE; BREAST TUMOR; CANCER CELL CULTURE; COLON CARCINOMA; CONTROLLED STUDY; CRYSTAL STRUCTURE; CYTOTOXICITY; DRUG STRUCTURE; DRUG SYNTHESIS; HUMAN; HUMAN CELL; IN VITRO STUDY; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PRIORITY JOURNAL; UTERINE CERVIX TUMOR;

ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; CELL SURVIVAL; CRYSTALLOGRAPHY, X-RAY; HUMANS; MAGNETIC RESONANCE SPECTROSCOPY; MOLECULAR STRUCTURE; NEOPLASMS; ORGANOTIN COMPOUNDS; SCHIFF BASES; SPECTROPHOTOMETRY, INFRARED; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 70349246880     PISSN: 01676997     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10637-008-9189-1     Document Type: Article

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