Ki-67 and p53 correlation prognostic value in squamous cell carcinomas of the oral cavity and tongue

Brazilian Journal of Otorhinolaryngology

Volumn 75, Issue 4, 2009, Pages 544-549

  Da Ros Motta, Rafael ^d   Zettler, Claudio Galeano ^a,b   Cambruzzi, Eduardo ^a   Jotz, Geraldo Pereira ^a,c   Berni, Renata Brutti ^a  

^a UNIVERSIDADE LUTERANA DO BRASIL   (Brazil)

^b UNIVERSIDADE FEDERAL DE CIÊNCIAS DA SAÚDE DE PORTO ALEGRE   (Brazil)

^c FEDERAL UNIVERSITY OF RIO GRANDE DO SUL   (Brazil)

^d Departamento de Patologia ^*  (Brazil)

Author keywords

ki67 antigen; Oral cavity; p53; Prognosis; Squamous cell carcinoma

Indexed keywords

MONOCLONAL ANTIBODY KI 67; PROTEIN P53;

ARTICLE; CANCER GRADING; CANCER STAGING; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LYMPH NODE METASTASIS; LYMPHADENECTOMY; MALE; MOUTH CARCINOMA; PROGNOSIS; PROTEIN EXPRESSION; RETROSPECTIVE STUDY; SQUAMOUS CELL CARCINOMA; TONGUE CARCINOMA; TUMOR VOLUME;

EID: 70349246448     PISSN: 18088694     EISSN: 18088686     Source Type: Journal    
DOI: 10.1016/S1808-8694(15)30494-8     Document Type: Article

References (24)

1. Friedlander PL, Schantz SP, Shaha AR, Yu G, Shah JP. Squamous cell carcinoma of the tongue in young patients: a matched-pair analysis. Head & Neck. 1998;20:363-368 (Pubitemid 28288056)
2. Llewellyn CD, Johnson NW, Warnakulasuriya KAAS. Risk factors for squamous cell carcinoma of the oral cavity in young people - a comprehensive literature review. Oral Oncol. 2001;37:401-418
3. Lopes FF, Cutrim MCFN, Casal CP, Fagundes DM, Montoro LA. Aspectos epidemiológicos e terapêuticos do câncer bucal. Rev Bras Odontol. 2002;59(2):98-99
4. Padovan P, Salmaro R, Marchethi M, Padovan R. Prognostic value of bcl-2, p53, Ki-67 in invasive squamous carcinoma of the uterine cervix. Eur J Gynaecol Oncol. 2000;21(3):267-272
5. Pich A, Chiusa L, Navone R. Prognostic relevance of cell proliferation in head and neck tumors. Ann Oncol. 2004;15(9):1319-1329 (Pubitemid 39295019)
6. Bruner JM, Connely JH, Saya H. p53 protein imunostaining in routinely paraffin-embedded section. Mod Pathol. 1993; 6(2):189-194
7. Linden MD, Nathanson SD, Zarbo RJ. Evalution of anti-p53 antibody staining quality control and technical considerations. Appl Immunohistochem. 1994;2:218-224
8. Tubiana M, Courdi A. Cell proliferation kinetics in human solid tumors:relation to probability of metastatic dissemination and long term survival. Radiother Oncol. 1989;15:1-18. (Pubitemid 19147615)
9. Forastiere A, Koch W, Trotti A, Sidransky D. Head and neck cancer. N Engl J Med. 2001;345:1890-1900
10. Van Diest PJ, Brugal G, Baak JPA. Proliferation markers in tumours: interpretation and clinical value. J Clin Pathol. 1998;51:716-724 (Pubitemid 28480326)
11. Nakanishi Y, Nogushi M, Matsuno Y, Mukai K, Shimosato Y, Hirohashi S. p53 expression in squamous cell carcinoma and dysplasia of the vocal cords and oral cavity. Appl Immunohistochem. 1993;1:101-107
12. Han U, Can OI, Han S, Kayhan B, Onal BU. Expressions of p53, VEGF C, p21:could they be used in preoperative evaluation of lymph node metastasis of esophageal squamous cell carcinoma? Dis Esophagus. 2007;20(5):379-385
13. Zohrabian VM, Nandu H, Gulati N, Khitrov G, Zhao C, Mohan A, et al. Gene expression profiling of metastatic brain cancer. Oncol Rep. 2007;18(2):321-328
14. Oliveira LR, Ribeiro-Silva A, Zucoloto S. Prognostic significance of p53 and p63 immunolocalisation in primary and matched lymph node metastasis in oral squamous cell carcinoma. Acta Histochem. 2007;109 (5):388-396 (Pubitemid 47496172)
15. Oliveira LR, Ribeiro-Silva A, Zucoloto S. Prognostic impact of p53 and p63 immunoexpression in oral squamous cell carcinoma. J Oral Pathol Med. 2007;36(4):191-197 (Pubitemid 46495983)
16. Carlos de Vicente J, Junquera Gutiérrez LM, Zapatero AH, Fresno Forcelledo MF, Hernández-Vallejo G, López Arranz JS. Prognostic significance of p53 expression in oral squamous cell carcinoma without neck node metastases. 1:Head & Neck. 2004;26(1):22-30.
17. Kurokawa H, Zhang M, Matsumoto S, Yamashita Y, Tanaka T, Tomoyose T, et al. The relationship of the histologic grade at the deep invasive front and the expression of Ki-67 antigen and p53 protein in oral squamous cell carcinoma. J Oral Pathol Med. 2005;34(10):602-607 (Pubitemid 41512946)
18. Myoung H, Kim MJ, Lee JH, Ok YJ, Paeng JY, Yun PY. Correlation of proliferative markers (Ki-67 and PCNA) with survival and lymph node metastasis in oral squamous cell carcinoma:a clinical and histopathological analysis of 113 patients. Int J Oral Maxillofac Surg. 2006;11:1005-1010 (Pubitemid 44615441)
19. Iamaroon A, Khemaleelakul U, Pongsiriwet S, Pintong J. Co-expression of p53 and Ki67 and lack EBV expression in oral squamous cell carcinoma. J Oral Pathol Med. 2004;33(1):30-36 (Pubitemid 38159974)
20. Lavertu P, Aldestein DJ, Myles J, Secic M. P53 and Ki-67 as outcome predictors for advanced squamous cell cancers of the head and neck treated with chemoradiotherapy. Laryngoscope. 2001;111(11 Pt 1):1878-1892 (Pubitemid 33042097)
21. Chew MH, Khoo JB, Chong VF, Tai BC, Soo KC, Lim DT. Significance of tumour volume measurements in tongue cancer:a novel role in staging. ANZ J Surg. 2007;77(8):632-637
22. Chua DT, Sham JS, Kwong DL, Tai KS, Wu PM, Lo M, et al. Volumetric analysis of tumor extent in nasopharyngeal carcinoma and correlation with treatment outcome. Int J Radiat Oncol Biol Phys. 1997;39 (3):711-719
23. Lee CC, Chu ST, Ho HC, Lee CC, Hung SK. Primary tumor volume calculation as a predictive factor of prognosis in nasopharyngeal carcinoma. Acta Otolaryngol. 2007;1-5.
24. Chua DT, Sham JS, Leung LH, Tai KS, Au GK. Tumor volume is not an independent prognostic factor in early-stage nasopharyngeal carcinoma treated by radiotherapy alone. Int J Radiat Oncol Biol Phys. 2004;58 (5):1437-1444