The C-type lectin-like receptor CLEC-1, expressed by myeloid cells and endothelial cells, is up-regulated by immunoregulatory mediators and moderates T cell activation

Journal of Immunology

Volumn 183, Issue 5, 2009, Pages 3099-3108

  Thebault, Pamela ^a   Lhermite, Natacha ^a   Tilly, Gaëlle ^a   Le Texier, Laëtitia ^a   Quillard, Thibaut ^a   Heslan, Michele ^a   Anegon, Ignacio ^a   Soulillou, Jean Paul ^a   Brouard, Sophie ^a   Charreau, Beatrice ^a   Cuturi, Maria Cristina ^a   Chiffoleau, Elise ^a  

^a NONE

Author keywords

[No Author keywords available]

Indexed keywords

ALLOANTIGEN; C TYPE LECTIN LIKE RECEPTOR 1; INTERLEUKIN 10; INTERLEUKIN 17; LECTIN RECEPTOR; TRANSCRIPTION FACTOR FOXP3; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG; AUTACOID; CLEC 1 PROTEIN, RAT; CLEC-1 PROTEIN, RAT; LECTIN;

ALLOGRAFT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BONE MARROW CELL; CD4+ CD25+ T LYMPHOCYTE; CELL DIFFERENTIATION; CELL SPECIFICITY; CELL STIMULATION; CHRONIC GRAFT REJECTION; CONTROLLED STUDY; CYTOKINE PRODUCTION; DOWN REGULATION; ENDOTHELIUM CELL; ENZYME INHIBITION; IMMUNE RESPONSE; IMMUNOREGULATION; IN VITRO STUDY; INFLAMMATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; REGULATORY T LYMPHOCYTE; T LYMPHOCYTE ACTIVATION; TH17 CELL; UPREGULATION; AMINO ACID SEQUENCE; ANIMAL; BIOSYNTHESIS; CELL CULTURE; CELL LINE; DRUG ANTAGONISM; GENE EXPRESSION REGULATION; GENETICS; GRAFT SURVIVAL; HEART TRANSPLANTATION; IMMUNOLOGICAL TOLERANCE; IMMUNOLOGY; LEWIS RAT; LYMPHOCYTE ACTIVATION; METABOLISM; MOLECULAR GENETICS; PATHOLOGY; PHYSIOLOGY; T LYMPHOCYTE SUBPOPULATION;

AMINO ACID SEQUENCE; ANIMALS; CELL LINE; CELLS, CULTURED; ENDOTHELIAL CELLS; GENE EXPRESSION REGULATION; GRAFT SURVIVAL; HEART TRANSPLANTATION; IMMUNE TOLERANCE; INFLAMMATION MEDIATORS; LECTINS, C-TYPE; LYMPHOCYTE ACTIVATION; MOLECULAR SEQUENCE DATA; MYELOID CELLS; RATS; RATS, INBRED LEW; T-LYMPHOCYTE SUBSETS; UP-REGULATION;

EID: 70349244893     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.0803767     Document Type: Article

References (36)

1. Robinson, M. J., D. Sancho, E. C. Slack, S. LeibundGut-Landmann, and C. Reis e Sousa. 2006. Myeloid C-type lectins in innate immunity. Nat. Immunol. 7: 1258-1265.
2. Leibundgut-Landmann, S., F. Osorio, G. D. Brown, and C. Reis e Sousa. 2008. Stimulation of dendritic cells via the dectin-1/Syk pathway allows priming of cytotoxic T-cell responses. Blood 112: 4971-4980.
3. Sobanov, Y., A. Bernreiter, S. Derdak, D. Mechtcheriakova, B. Schweighofer, M. Duchler, F. Kalthoff, and E. Hofer. 2001. A novel cluster of lectin-like receptor genes expressed in monocytic, dendritic and endothelial cells maps close to the NK receptor genes in the human NK gene complex. Eur. J. Immunol. 31: 3493-3503.
4. Oka, K., T. Sawamura, K. Kikuta, S. Itokawa, N. Kume, T. Kita, and T. Masaki. 1998. Lectin-like oxidized low-density lipoprotein receptor 1 mediates phagocytosis of aged/apoptotic cells in endothelial cells. Proc. Natl. Acad. Sci. USA 95: 9535-9540.
5. Theriault, J. R., S. S. Mambula, T. Sawamura, M. A. Stevenson, and S. K. Calderwood. 2005. Extracellular HSP70 binding to surface receptors present on antigen presenting cells and endothelial/epithelial cells. FEBS Lett. 579: 1951-1960.
6. Renie, G., F. Maingrette, and L. Li. 2007. Diabetic vasculopathy and the lectin-like oxidized low-density lipoprotein receptor-1 (LOX-1). Curr. Diabetes Rev. 3: 103-110.
7. LeibundGut-Landmann, S., O. Gross, M. J. Robinson, F. Osorio, E. C. Slack, S. V. Tsoni, E. Schweighoffer, V. Tybulewicz, G. D. Brown, J. Ruland, and C. Reis e Sousa. 2007. Syk- and CARD9-dependent coupling of innate immunity to the induction of T helper cells that produce interleukin 17. Nat. Immunol. 8: 630-638.
8. Heslan, J. M., K. Renaudin, P. Thebault, R. Josien, M. C. Cuturi, and E. Chiffoleau. 2006. New evidence for a role of allograft accommodation in long-term tolerance. Transplantation 82: 1185-1193.
9. Heslan, J. M., G. Beriou, J. B. Le Luduec, C. Guillonneau, I. Anegon, J. P. Soulillou, M. C. Cuturi, and E. Chiffoleau. 2005. Accumulation of T cells with potent regulatory properties and restricted Vβ7-TCR rearrangements in tolerated allografts. Transplantation 80: 1476-1484.
10. + regulatory T cells by induction of IDO in endothelial cells. Am. J. Transplant. 7: 2472-2482.
11. Colonna, M., J. Samaridis, and L. Angman. 2000. Molecular characterization of two novel C-type lectin-like receptors, one of which is selectively expressed in human dendritic cells. Eur. J. Immunol. 30: 697-704.
12. Chiffoleau, E., G. Beriou, P. Dutartre, C. Usal, J. P. Soulillou, and M. C. Cuturi. 2002. Induction of donor-specific allograft tolerance by short-term treatment with LF15-0195 after transplantation: evidence for a direct effect on T-cell differentiation. Am. J. Transplant. 2: 745-757.
13. Jovanovic, V., A. S. Dugast, J. M. Heslan, J. Ashton-Chess, M. Giral, N. Degauque, A. Moreau, A. Pallier, E. Chiffoleau, D. Lair, et al. 2008. Implication of matrix metalloproteinase 7 and the noncanonical wingless-type signaling pathway in a model of kidney allograft tolerance induced by the administration of anti-donor class II antibodies. J. Immunol. 180: 1317-1325.
14. Guillonneau, C., V. Aubry, K. Renaudin, C. Seveno, C. Usal, K. Tezuka, and I. Anegon. 2005. Inhibition of chronic rejection and development of tolerogenic T cells after ICOS-ICOSL and CD40-CD40L co-stimulation blockade. Transplantation 80: 255-263.
15. Peche, H., M. Heslan, C. Usal, S. Amigorena, and M. C. Cuturi. 2003. Presentation of donor major histocompatibility complex antigens by bone marrow dendritic cell-derived exosomes modulates allograft rejection. Transplantation 76: 1503-1510.
16. + T cell. Int. Immunol. 19: 193-201.
17. Charreau, B., A. Cassard, L. Tesson, B. Le Mauff, J.-M. Navenot, D. Blanchard, D. Lublin, J. P. Soulillou, and I. Anegon. 1994. Protection of rat endothelial cells from primate complement-mediated lysis by expression of human CD59 and/or decay-accelerating factor. Transplantation 58: 1222-1229.
18. Le Bas-Bernardet, S., M. Hourmant, S. Coupel, J. D. Bignon, J. P. Soulillou, and B. Charreau. 2003. Non-HLA-type endothelial cell reactive alloantibodies in pre-transplant sera of kidney recipients trigger apoptosis. Am. J. Transplant. 3: 167-177.
19. Spisek, R., L. Bretaudeau, I. Barbieux, K. Meflah, and M. Gregoire. 2001. Standardized generation of fully mature p70 IL-12 secreting monocyte-derived dendritic cells for clinical use. Cancer Immunol. Immunother. 50: 417-427.
20. + T cells in allograft tolerance induced by donor specific blood transfusion. Transplantation 78: 1259-1266.
21. -ΔΔC(T) method. Methods 25: 402-408.
22. + cells. J. Immunol. 176: 3915-3922.
23. + T cells induced by donor dendritic cells in allograft tolerance by LF15-0195 treatment. J. Immunol. 168: 5058-5069.
24. Klatt, A. R., G. Klinger, D. Zech, B. Paul-Klausch, J. H. Renno, J. Schmidt, G. Malchau, and K. Wielckens. 2007. RNAi in primary human chondrocytes: efficiencies, kinetics, and non-specific effects of siRNA-mediated gene suppression. Biologicals 35: 321-328.
25. Kanazawa, N. 2007. Dendritic cell immunoreceptors: C-type lectin receptors for pattern-recognition and signaling on antigen-presenting cells. J. Dermatol. Sci. 45: 77-86.
26. + T cell-mediated suppression by dendritic cells. Science 299: 1033-1036.
27. Bettelli, E., Y. Carrier, W. Gao, T. Korn, T. B. Strom, M. Oukka, H. L. Weiner, and V. K. Kuchroo. 2006. Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells. Nature 441: 235-238.
28. Chang, C., R. Ciubotariu, J. Manavalan, J. Yuan, A. Colovai, F. Piazza, S. Lederman, M. Colonna, R. Cortesini, R. Dalla-Favera, and N. Suciu-Foca. 2002. Tolerization of dendritic cells by Ts cells: the crucial role of inhibitory ILT3 and ILT4. Nat. Immunol. 3: 237-243.
29. + T suppressor cells mediate tolerance to allogeneic heart transplants, inducing PIR-B in APC and rendering the graft invulnerable to rejection. Transplant Immunol. 13: 239-247.
30. Rao, D. A., R. E. Eid, L. Qin, T. Yi, N. C. Kirkiles-Smith, G. Tellides, and J. S. Pober. 2008. Interleukin (IL)-1 promotes allogeneic T cell intimal infiltration and IL-17 production in a model of human artery rejection. J. Exp. Med. 205: 3145-3158.
31. Yuan, X., J. Paez-Cortez, I. Schmitt-Knosalla, F. D'Addio, B. Mfarrej, M. Donnarumma, A. Habicht, M. R. Clarkson, J. Iacomini, L. H. Glimcher, et al. 2008. A novel role of CD4 Th17 cells in mediating cardiac allograft rejection and vasculopathy. J. Exp. Med. 205: 3133-3144.
32. Gantner, B. N., R. M. Simmons, S. J. Canavera, S. Akira, and D. M. Underhill. 2003. Collaborative induction of inflammatory responses by dectin-1 and Toll-like receptor 2. J. Exp. Med. 197: 1107-1117. (Pubitemid 36570066)
33. Chen, C. H., H. Floyd, N. E. Olson, D. Magaletti, C. Li, K. Draves, and E. A. Clark. 2006. Dendritic-cell-associated C-type lectin 2 (DCAL-2) alters dendritic-cell maturation and cytokine production. Blood 107: 1459-1467.
34. Ryan, E. J., A. J. Marshall, D. Magaletti, H. Floyd, K. E. Draves, N. E. Olson, and E. A. Clark. 2002. Dendritic cell-associated lectin-1: a novel dendritic cell-associated, C-type lectin-like molecule enhances T cell secretion of IL-4. J. Immunol. 169: 5638-5648.
35. Osorio, F., S. LeibundGut-Landmann, M. Lochner, K. Lahl, T. Sparwasser, G. Eberl, and C. Reis e Sousa. 2008. DC activated via dectin-1 convert Treg into IL-17 producers. Eur. J. Immunol. 38: 3274-3281.
36. Kuttruff, S., S. Koch, A. Kelp, G. Pawelec, H. G. Rammensee, and A. Steinle. 2009. NKp80 defines and stimulates a reactive subset of CD8 T cells. Blood 113: 358-369.