메뉴 건너뛰기




Volumn 48, Issue 9, 2009, Pages 983-989

Current state of systemic therapy of metastatic renal cell carcinoma;Aktuelles zur Systemtherapie des metastasierten Nierenzellkarzinoms

Author keywords

Metastases; Prognosis; Renal cell carcinoma; Targeted therapy

Indexed keywords

AFINITOR; ALPHA INTERFERON; AXITINIB; BEVACIZUMAB; EVEROLIMUS; PAZOPANIB; PLACEBO; SORAFENIB; SUNITINIB; TEMSIROLIMUS; UNCLASSIFIED DRUG; VASCULOTROPIN;

EID: 70349244672     PISSN: 03402592     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00120-009-2072-7     Document Type: Review
Times cited : (5)

References (31)
  • 1
    • 53249117351 scopus 로고    scopus 로고
    • Value of targeted therapies for renal cell cancer
    • Merseburger AS, Kuczyk MA (2008) Value of targeted therapies for renal cell cancer. Urologe A 47:1303-1310
    • (2008) Urologe A , vol.47 , pp. 1303-1310
    • Merseburger, A.S.1    Kuczyk, M.A.2
  • 2
    • 53249084478 scopus 로고    scopus 로고
    • Systemic therapy of metastasizing renal cell carcinoma
    • Staehler M, Haseke N, Zilinberg K et al (2008) Systemic therapy of metastasizing renal cell carcinoma. Urologe A 47:1357-1367
    • (2008) Urologe A , vol.47 , pp. 1357-1367
    • Staehler, M.1    Haseke, N.2    Zilinberg, K.3
  • 3
    • 0032772880 scopus 로고    scopus 로고
    • Survival and prognostic stratification of 670 patients with advanced renal cell carcinoma
    • Motzer RJ, Mazumdar M, Bacik J et al (1999) Survival and prognostic stratification of 670 patients with advanced renal cell carcinoma. J Clin Oncol 17:2530-2540
    • (1999) J Clin Oncol , vol.17 , pp. 2530-2540
    • Motzer, R.J.1    Mazumdar, M.2    Bacik, J.3
  • 4
    • 34547776805 scopus 로고    scopus 로고
    • Interdisciplinary recommendations on targeted therapy in the treatment of renal cell carcinoma
    • Miller K, Bergmann L, Albers P et al (2007) Interdisciplinary recommendations on targeted therapy in the treatment of renal cell carcinoma. Aktuel Urol 38:328-330
    • (2007) Aktuel Urol , vol.38 , pp. 328-330
    • Miller, K.1    Bergmann, L.2    Albers, P.3
  • 6
    • 48649094719 scopus 로고    scopus 로고
    • Overall survival with sunitinib versus interferon (IFN)-alfa as first-line treatment of metastatic renal cell carcinoma (mRCC)
    • Figlin RA, Hutson TE, Tomczak P et al (2008) Overall survival with sunitinib versus interferon (IFN)-alfa as first-line treatment of metastatic renal cell carcinoma (mRCC). J Clin Oncol 26:5024
    • (2008) J Clin Oncol , vol.26 , pp. 5024
    • Figlin, R.A.1    Hutson, T.E.2    Tomczak, P.3
  • 7
    • 60649096276 scopus 로고    scopus 로고
    • Can Tyrosine Kinase inhibitors be discontinued in patients with metastatic Renal Cell Carcinoma and a complete response to treatment? A Multicentre, Retrospective Analysis
    • Johannsen M, Florcken A, Bex A et al (2008) Can Tyrosine Kinase inhibitors be discontinued in patients with metastatic Renal Cell Carcinoma and a complete response to treatment? A Multicentre, Retrospective Analysis. Eur Urol 53:917-930
    • (2008) Eur Urol , vol.53 , pp. 917-930
    • Johannsen, M.1    Florcken, A.2    Bex, A.3
  • 8
    • 37349080670 scopus 로고    scopus 로고
    • Bevacizumab plus interferon alfa-2a for treatment of metastatic renal cell carcinoma: A randomised, double-blind phase III trial
    • Escudier B, Pluzanska A, Koralewski P et al (2007) Bevacizumab plus interferon alfa-2a for treatment of metastatic renal cell carcinoma: a randomised, double-blind phase III trial. Lancet 370:2103-2111
    • (2007) Lancet , vol.370 , pp. 2103-2111
    • Escudier, B.1    Pluzanska, A.2    Koralewski, P.3
  • 9
    • 70349264943 scopus 로고    scopus 로고
    • Final results of the phase III, randomized, double-blind AVOREN trial of first-line bevacizumab (BEV) + interferon-{alpha}2a (IFN) in metastatic renal cell carcinoma (mRCC)
    • Escudier BJ, Bellmunt J, Negrier S et al (2009) Final results of the phase III, randomized, double-blind AVOREN trial of first-line bevacizumab (BEV) + interferon-{alpha}2a (IFN) in metastatic renal cell carcinoma (mRCC). J Clin Oncol 27:5020
    • (2009) J Clin Oncol , vol.27 , pp. 5020
    • Escudier, B.J.1    Bellmunt, J.2    Negrier, S.3
  • 10
    • 70349283555 scopus 로고    scopus 로고
    • Bevacizumab plus interferon alfa versus interferon al-fa monotherapy in patients with metastatic Renal Cell Carcinoma: Results of overall survival for CALGB 90206
    • Rini BI, Halabi S, Rosenberg JE et al (2009) Bevacizumab plus interferon alfa versus interferon al-fa monotherapy in patients with metastatic Renal Cell Carcinoma: Results of overall survival for CALGB 90206. J Clin Oncol 27(Suppl 2): 235-241
    • (2009) J Clin Oncol , vol.27 , Issue.SUPPL. 2 , pp. 235-241
    • Rini, B.I.1    Halabi, S.2    Rosenberg, J.E.3
  • 12
    • 33846148701 scopus 로고    scopus 로고
    • Sorafe-nib in advanced clear-cell renal-cell carcinoma
    • Escudier B, EisenT, Stadler WM et al (2007) Sorafe-nib in advanced clear-cell renal-cell carcinoma. N Engl J Med 356:125-134
    • (2007) N Engl J Med , vol.356 , pp. 125-134
    • Escudier, B.1    Eisent Stadler, W.M.2
  • 13
    • 65549084974 scopus 로고    scopus 로고
    • A phase II trial of intra-patient dose escalated-sorafenib in patients (pts) with metastatic renal cell cancer (MRCC)
    • Amato RJ, Jac J, Harris P et al (2008) A phase II trial of intra-patient dose escalated-sorafenib in patients (pts) with metastatic renal cell cancer (MRCC). J Clin Oncol 26:5122
    • (2008) J Clin Oncol , vol.26 , pp. 5122
    • Amato, R.J.1    Jac, J.2    Harris, P.3
  • 14
    • 77952878654 scopus 로고    scopus 로고
    • Updated data from a phase III randomized trial of evero-limus (RAD001) versus PBO in metastatic renal cell carcinoma (mRCC)
    • Kay RM A, Figlin R, Escudier B et al (2009) Updated data from a phase III randomized trial of evero-limus (RAD001) versus PBO in metastatic renal cell carcinoma (mRCC). J Clin Oncol 27(15):5032
    • (2009) J Clin Oncol , vol.27 , Issue.15 , pp. 5032
    • Kay Rm, A.1    Figlin, R.2    Escudier, B.3
  • 15
    • 48649107474 scopus 로고    scopus 로고
    • Efficacy of everolimus in advanced renal cell carcinoma: A double-blind, randomised, placebo-controlled phase III trial
    • Motzer RJ, Escudier B, Oudard S et al (2008) Efficacy of everolimus in advanced renal cell carcinoma: a double-blind, randomised, placebo-controlled phase III trial. Lancet 372:449-456
    • (2008) Lancet , vol.372 , pp. 449-456
    • Motzer, R.J.1    Escudier, B.2    Oudard, S.3
  • 16
    • 58949092548 scopus 로고    scopus 로고
    • Sequential therapy with sorafenib and sunitinib in renal cell carcinoma
    • Dudek AZ, Zolnierek J, Dham A et al (2009) Sequential therapy with sorafenib and sunitinib in renal cell carcinoma. Cancer 115:61-67
    • (2009) Cancer , vol.115 , pp. 61-67
    • Dudek, A.Z.1    Zolnierek, J.2    Dham, A.3
  • 17
    • 55649103188 scopus 로고    scopus 로고
    • Sequential use of the tyrosine kinase inhibitors sorafenib and sunitinib in metastatic renal cell carcinoma: A retrospective outcome analysis
    • Eichelberg C, Heuer R, Chun FK et al (2008) Sequential use of the tyrosine kinase inhibitors sorafenib and sunitinib in metastatic renal cell carcinoma: a retrospective outcome analysis. Eur Urol 54:1373-1378
    • (2008) Eur Urol , vol.54 , pp. 1373-1378
    • Eichelberg, C.1    Heuer Chun, R.F.K.2
  • 18
    • 49549086867 scopus 로고    scopus 로고
    • Prospective comparison of sorafenib and sunitinib for second-line treatment of cytokine-refractory kidney cancer patients
    • Herrmann E, BiererS, Gerss J et al (2008) Prospective comparison of sorafenib and sunitinib for second-line treatment of cytokine-refractory kidney cancer patients. Oncology 74:216-222
    • (2008) Oncology , vol.74 , pp. 216-222
    • Herrmann, E.1    Bierers Gerss, J.2
  • 19
    • 70349262401 scopus 로고    scopus 로고
    • Retrospective analysis of the sequential use of sorafenib and sunitinib in patients with advanced renal cell carcinoma (RCC)
    • Porta CPG, Sabbatini R, Bearz A et al (2008) Retrospective analysis of the sequential use of sorafenib and sunitinib in patients with advanced renal cell carcinoma (RCC). Eur Urol 252(Suppl)
    • (2008) Eur Urol , vol.252 , Issue.SUPPL.
    • Porta, C.P.G.1    Sabbatini, R.2    Bearz, A.3
  • 20
    • 67349163859 scopus 로고    scopus 로고
    • Sequential sorafenib and sunitinib for renal cell carcinoma
    • Sablin MP, Negrier S, Ravaud A et al (2009) Sequential sorafenib and sunitinib for renal cell carcinoma. J Urol 182:29-34
    • (2009) J Urol , vol.182 , pp. 29-34
    • Sablin, M.P.1    Negrier, S.2    Ravaud, A.3
  • 21
    • 36749064602 scopus 로고    scopus 로고
    • Antitu-mor effects of sunitinib or sorafenib in patients with metastatic renal cell carcinoma who received prior antiangiogenic therapy
    • Tamaskar I, Garcia JA, Elson P et al (2008) Antitu-mor effects of sunitinib or sorafenib in patients with metastatic renal cell carcinoma who received prior antiangiogenic therapy. J Urol 179:81-86
    • (2008) J Urol , vol.179 , pp. 81-86
    • Tamaskar, I.1    Garcia, J.A.2    Elson, P.3
  • 22
    • 62849099971 scopus 로고    scopus 로고
    • Sunitinib treatment for patients with advanced clear-cell renal-cell carcinoma after progression on sorafenib
    • Zimmermann K, Schmittel A, Steiner U et al (2009) Sunitinib treatment for patients with advanced clear-cell renal-cell carcinoma after progression on sorafenib. Oncology 76:350-354
    • (2009) Oncology , vol.76 , pp. 350-354
    • Zimmermann, K.1    Schmittel, A.2    Steiner, U.3
  • 23
    • 0035818877 scopus 로고    scopus 로고
    • Nephrectomy followed by interferon alfa-2b compared with interferon alfa-2b alone for metastatic renal-cell cancer
    • Flanigan RC, Salmon SE, Blumenstein BA et al (2001) Nephrectomy followed by interferon alfa-2b compared with interferon alfa-2b alone for metastatic renal-cell cancer. N Engl J Med 345:1655-1659
    • (2001) N Engl J Med , vol.345 , pp. 1655-1659
    • Flanigan, R.C.1    Salmon, S.E.2    Blumenstein, B.A.3
  • 24
    • 0035934596 scopus 로고    scopus 로고
    • Radical nephrectomy plus interferon-alfa-based im-munotherapy compared with interferon alfa alone in metastatic renal-cell carcinoma: A randomised trial
    • Mickisch GH, Garin A, van Poppel H et al (2001) Radical nephrectomy plus interferon-alfa-based im-munotherapy compared with interferon alfa alone in metastatic renal-cell carcinoma: a randomised trial. Lancet 358:966-970
    • (2001) Lancet , vol.358 , pp. 966-970
    • Mickisch, G.H.1    Garin, A.2    Van Poppel, H.3
  • 25
    • 1542327748 scopus 로고    scopus 로고
    • Cytoreductive nephrectomy in patients with metastatic renal cancer: A combined analysis
    • Flanigan RC, Mickisch G, Sylvester R et al (2004) Cytoreductive nephrectomy in patients with metastatic renal cancer: a combined analysis. J Urol 171:1071-1076
    • (2004) J Urol , vol.171 , pp. 1071-1076
    • Flanigan, R.C.1    Mickisch, G.2    Sylvester, R.3
  • 26
    • 55349094251 scopus 로고    scopus 로고
    • Sunitinib in patients with or without prior nephrectomy (Nx) in an expanded access trial of metastatic renal cell carcinoma (mRCC)
    • Szczylik C, Porta C, Bracarda S et al (2008) Sunitinib in patients with or without prior nephrectomy (Nx) in an expanded access trial of metastatic renal cell carcinoma (mRCC). J Clin Oncol 26:5124
    • (2008) J Clin Oncol , vol.26 , pp. 5124
    • Szczylik, C.1    Porta, C.2    Bracarda, S.3
  • 27
    • 56449127154 scopus 로고    scopus 로고
    • Loss of galectin-3 expression correlates with clear cell renal carcinoma progression and reduced survival
    • Merseburger AS, Kramer MW, Hennenlotter J et al (2008) Loss of galectin-3 expression correlates with clear cell renal carcinoma progression and reduced survival. World J Urol 26:637-642
    • (2008) World J Urol , vol.26 , pp. 637-642
    • Merseburger, A.S.1    Kramer, M.W.2    Hennenlotter, J.3
  • 28
    • 0037314709 scopus 로고    scopus 로고
    • Carbonic anhydrase IX is an independent predictor of survival in advanced renal clear cell carcinoma: Implications for prognosis and therapy
    • Bui MH, Seligson D, Han KR et al (2003) Carbonic anhydrase IX is an independent predictor of survival in advanced renal clear cell carcinoma: implications for prognosis and therapy. Clin Cancer Res 9:802-811
    • (2003) Clin Cancer Res , vol.9 , pp. 802-811
    • Bui, M.H.1    Seligson, D.2    Han, K.R.3
  • 29
    • 21044442672 scopus 로고    scopus 로고
    • Carbonic anhydrase IX expression predicts outcome of interleukin 2 therapy for renal cancer
    • Atkins M, Regan M, McDermott D et al (2005) Carbonic anhydrase IX expression predicts outcome of interleukin 2 therapy for renal cancer. Clin Cancer Res 11:3714-3721
    • (2005) Clin Cancer Res , vol.11 , pp. 3714-3721
    • Atkins, M.1    Regan, M.2    McDermott, D.3
  • 30
    • 70349253166 scopus 로고    scopus 로고
    • A randomized, double-blind phase III study of pazopa-nib in treatment-naive and cytokine-pretreated patients with advanced renal cell carcinoma (RCC)
    • Sternberg CN, Szczylik C, Lee E et al (2009) A randomized, double-blind phase III study of pazopa-nib in treatment-naive and cytokine-pretreated patients with advanced renal cell carcinoma (RCC). J Clin Oncol 27:5021
    • (2009) J Clin Oncol , vol.27 , pp. 5021
    • Sternberg, C.N.1    Szczylik, C.2    Lee, E.3
  • 31
    • 35448934762 scopus 로고    scopus 로고
    • Axitinib treatment in patients with cytokine-refractory metastatic renal-cell cancer: A phase II study
    • Rixe O, Bukowski RM, Michaelson MD et al (2007) Axitinib treatment in patients with cytokine-refractory metastatic renal-cell cancer: a phase II study. Lancet Oncol 8:975-984
    • (2007) Lancet Oncol , vol.8 , pp. 975-984
    • Rixe, O.1    Bukowski, R.M.2    Michaelson, M.D.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.