PRX-00023, a selective serotonin 1A receptor agonist, reduces ultrasonic vocalizations in infant rats bred for high infantile anxiety

Pharmacology Biochemistry and Behavior

Volumn 94, Issue 1, 2009, Pages 8-15

  Brunelli, Susan A ^a,b   Aviles, Jessica A ^c   Gannon, Kimberly S ^d   Branscomb, Aron ^b   Shacham, Sharon ^d  

^a NEW YORK STATE PSYCHIATRIC INSTITUTE   (United States)

^b Columbia University College of Physicians and Surgeons ^*  (United States)

^c Saint Francis Preparatory School   (United States)

^d Epix Pharmaceuticals   (United States)

Author keywords

5 HT1A receptor; Anxiety; Depression; Development; Genetic model; Rat; Selective breeding; Ultrasonic vocalizations

Indexed keywords

BUSPIRONE; N [3 [4 [4 (CYCLOHEXYLMETHYLSULFONAMIDO)BUTYL] 1 PIPERAZINYL]PHENYL]ACETAMIDE; SEROTONIN 1A AGONIST;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANXIETY; ANXIETY DISORDER; ARTICLE; DEPRESSION; DRUG MECHANISM; DRUG TARGETING; MATERNAL DEPRIVATION; NONHUMAN; PERINATAL PERIOD; PHENOTYPE; PRESYNAPTIC NERVE; PRIORITY JOURNAL; RAT; SOMNOLENCE; ULTRASOUND; VOCALIZATION;

AGING; ANIMALS; ANTI-ANXIETY AGENTS; ANXIETY; ANXIETY DISORDERS; ANXIETY, SEPARATION; ATAXIA; BODY TEMPERATURE; BUSPIRONE; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; ELIMINATIVE BEHAVIOR, ANIMAL; FEMALE; GROOMING; HYBRIDIZATION, GENETIC; MALE; MOVEMENT; PIPERAZINES; RATS; REACTION TIME; RECEPTOR, SEROTONIN, 5-HT1A; SEX CHARACTERISTICS; SOCIAL ISOLATION; SULFONAMIDES; ULTRASONICS; VOCALIZATION, ANIMAL;

RATTUS;

EID: 70349216372     PISSN: 00913057     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.pbb.2009.06.014     Document Type: Article

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