Iron-catalysed Suzuki coupling? A cautionary tale

Tetrahedron Letters

Volumn 50, Issue 45, 2009, Pages 6110-6111

  Bedford, Robin B ^a   Nakamura, Masaharu ^b   Gower, Nicholas J ^a   Haddow, Mairi F ^a   Hall, Mark A ^a   Huwe, Michael ^a   Hashimoto, Tohru ^b,c   Okopie, Rukeme A ^a  

^a UNIVERSITY OF BRISTOL   (United Kingdom)

^b KYOTO UNIVERSITY   (Japan)

^c KYOTO UNIVERSITY   (Japan)

Author keywords

Biaryls; Iron catalysts; Pyridine ligands; Suzuki cross coupling

Indexed keywords

FERRIC ION; FERROUS ION; METAL COMPLEX; PALLADIUM ACETATE; PYRIDINE DERIVATIVE; TRACE ELEMENT;

ARTICLE; CATALYSIS; CONTAMINATION; CONTROLLED STUDY; CROSS COUPLING REACTION; CRYSTAL STRUCTURE; FALSE POSITIVE RESULT; SUZUKI REACTION;

EID: 70349213356     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tetlet.2009.08.022     Document Type: Article

References (21)

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14. obs = 4.72 B.M.
15. 1 a = 8.9730(7), b = 16.8433(14), and c = 14.4058(12). Crystallographic data (excluding structure factors) for the room temperature structure of 2 have been deposited with the Cambridge Crystallographic Data Centre as Supplementary Publication No. CCDC 738763. Copies of the data can be obtained, free of charge, on application to CCDC, 12 Union Road, Cambridge CB2 1EZ, UK, (fax: +44-(0)1223-336033 or e-mail: deposit@ccdc.cam.ac.Uk).
16. It is also worth considering the stability of 2 in water, under air at 80 °C. Under these conditions complex 2 underwent a rapid (seconds) change to a 'rusty' solid. This too was tested in catalysis as per the conditions in Table 1, entry 18, but no activity was observed.
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