-
1
-
-
0028817815
-
UK prospective diabetes study 16. Overview of 6 years' therapy of type II diabetes: A progressive disease
-
UK Prospective Diabetes Study Group
-
UK Prospective Diabetes Study Group. UK prospective diabetes study 16. Overview of 6 years' therapy of type II diabetes: A progressive disease. Diabetes 1995; 44(11): 1249-1258.
-
(1995)
Diabetes
, vol.44
, Issue.11
, pp. 1249-1258
-
-
-
2
-
-
0035408378
-
-
Davis TM, Cull CA, Holman RR. UK Prospective Diabetes Study (UKPDS) Group. Relationship between ethnicity and glycaemic control, lipid profiles, and blood pressure during the first 9 years of type 2 diabetes: U.K. Prospective Diabetes Study (UKPDS 55). Diabetes Care 2001; 24(7): 1167-1174.
-
Davis TM, Cull CA, Holman RR. UK Prospective Diabetes Study (UKPDS) Group. Relationship between ethnicity and glycaemic control, lipid profiles, and blood pressure during the first 9 years of type 2 diabetes: U.K. Prospective Diabetes Study (UKPDS 55). Diabetes Care 2001; 24(7): 1167-1174.
-
-
-
-
3
-
-
0020031051
-
The Bedford survey: Ten year mortality rates in newly diagnosed diabetics, borderline diabetics and normoglycaemic controls and risk indices for coronary heart disease in borderline diabetics
-
Jarrett RJ, McCartney P, Keen H. The Bedford survey: Ten year mortality rates in newly diagnosed diabetics, borderline diabetics and normoglycaemic controls and risk indices for coronary heart disease in borderline diabetics. Diabetologia 1982; 22(2): 79-84.
-
(1982)
Diabetologia
, vol.22
, Issue.2
, pp. 79-84
-
-
Jarrett, R.J.1
McCartney, P.2
Keen, H.3
-
4
-
-
0242269000
-
Insulin Glargine 4002 Study Investigators. The treat-to-target trial: Randomized addition of glargine or human NPH insulin to oral therapy of type 2 diabetic patients
-
Riddle MC, Rosenstock J, Gerich J. Insulin Glargine 4002 Study Investigators. The treat-to-target trial: Randomized addition of glargine or human NPH insulin to oral therapy of type 2 diabetic patients. Diabetes Care 2003; 26(11): 3080-3086.
-
(2003)
Diabetes Care
, vol.26
, Issue.11
, pp. 3080-3086
-
-
Riddle, M.C.1
Rosenstock, J.2
Gerich, J.3
-
5
-
-
33845405222
-
-
Kahn SE, Haffner SM, Heise MA, et al. ADOPT Study Group. Glycaemic durability of rosiglitazone, metformin, or glyburide monotherapy. N Engl J Med 2006; 7; 355(23): 2427-2443.
-
Kahn SE, Haffner SM, Heise MA, et al. ADOPT Study Group. Glycaemic durability of rosiglitazone, metformin, or glyburide monotherapy. N Engl J Med 2006; 7; 355(23): 2427-2443.
-
-
-
-
6
-
-
0032511566
-
Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34)
-
UK Prospective Diabetes Study (UKPDS) Group
-
UK Prospective Diabetes Study (UKPDS) Group. Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). Lancet 1998; 352(9131): 854-865.
-
(1998)
Lancet
, vol.352
, Issue.9131
, pp. 854-865
-
-
-
7
-
-
38149140236
-
Trends in A1C concentrations among US adults with diagnosed diabetes from 1999 to 2004
-
Ford ES, Li C, Little RR, Mokdad AH. Trends in A1C concentrations among US adults with diagnosed diabetes from 1999 to 2004. Diabetes Care 2008; 31(1): 102-104.
-
(2008)
Diabetes Care
, vol.31
, Issue.1
, pp. 102-104
-
-
Ford, E.S.1
Li, C.2
Little, R.R.3
Mokdad, A.H.4
-
8
-
-
0022617246
-
Reduced incretin effect in type 2 (non-insulin-dependent) diabetes
-
Nauck M, Stöckmann F, Ebert R, Creutzfeldt W. Reduced incretin effect in type 2 (non-insulin-dependent) diabetes. Diabetologia 1986; 29(1): 46-52.
-
(1986)
Diabetologia
, vol.29
, Issue.1
, pp. 46-52
-
-
Nauck, M.1
Stöckmann, F.2
Ebert, R.3
Creutzfeldt, W.4
-
9
-
-
0023638829
-
Glucagon-like peptide-1 7-36: A physiological incretin in man
-
Kreymann B, Williams G, Ghatei MA, Bloom SR. Glucagon-like peptide-1 7-36: A physiological incretin in man. Lancet 1987; 2(8571): 1300-1304.
-
(1987)
Lancet
, vol.2
, Issue.8571
, pp. 1300-1304
-
-
Kreymann, B.1
Williams, G.2
Ghatei, M.A.3
Bloom, S.R.4
-
10
-
-
0034880655
-
Determinants of the impaired secretion of glucagon-like peptide-1 in Type 2 diabetic patients
-
Toft-Nielsen MB, Damholt MB, Madsbad S, et al. Determinants of the impaired secretion of glucagon-like peptide-1 in Type 2 diabetic patients. J Clin Endocrinol Metab 2001; 86(8): 3717-3723.
-
(2001)
J Clin Endocrinol Metab
, vol.86
, Issue.8
, pp. 3717-3723
-
-
Toft-Nielsen, M.B.1
Damholt, M.B.2
Madsbad, S.3
-
11
-
-
0036373430
-
Defective amplification of the late phase insulin response to glucose by GIP in obese Type II diabetic patients
-
Vilsbøll T, Krarup T, Madsbad S, Holst JJ. Defective amplification of the late phase insulin response to glucose by GIP in obese Type II diabetic patients. Diabetologia 2002; 45(8): 1111-1119.
-
(2002)
Diabetologia
, vol.45
, Issue.8
, pp. 1111-1119
-
-
Vilsbøll, T.1
Krarup, T.2
Madsbad, S.3
Holst, J.J.4
-
12
-
-
0027248866
-
Normalization of fasting hyperglycaemia by exogenous glucagon-like peptide 1 (7-36 amide) in type 2 (non-insulin-dependent) diabetic patients
-
Nauck MA, Kleine N, Orskov C, Holst JJ, Willms B, Creutzfeldt W. Normalization of fasting hyperglycaemia by exogenous glucagon-like peptide 1 (7-36 amide) in type 2 (non-insulin-dependent) diabetic patients. Diabetologia 1993; 36(8): 741-744.
-
(1993)
Diabetologia
, vol.36
, Issue.8
, pp. 741-744
-
-
Nauck, M.A.1
Kleine, N.2
Orskov, C.3
Holst, J.J.4
Willms, B.5
Creutzfeldt, W.6
-
13
-
-
0035432607
-
Glucagon-like peptide-1 infusion must be maintained for 24 h/day to obtain acceptable glycemia in type 2 diabetic patients who are poorly controlled on sulphonylurea treatment
-
Larsen J, Hylleberg B, Ng K, Damsbo P. Glucagon-like peptide-1 infusion must be maintained for 24 h/day to obtain acceptable glycemia in type 2 diabetic patients who are poorly controlled on sulphonylurea treatment. Diabetes Care 2001; 24(8): 1416-1421.
-
(2001)
Diabetes Care
, vol.24
, Issue.8
, pp. 1416-1421
-
-
Larsen, J.1
Hylleberg, B.2
Ng, K.3
Damsbo, P.4
-
14
-
-
0029118049
-
Degradation of glucose-dependent insulinotropic polypeptide and truncated glucagon-like peptide 1 in vitro and in vivo by dipeptidyl peptidase IV
-
Kieffer TJ, Mcintosh CHS, Pederson RA. Degradation of glucose-dependent insulinotropic polypeptide and truncated glucagon-like peptide 1 in vitro and in vivo by dipeptidyl peptidase IV. Endocrinology 1995; 136(8): 3585-3596.
-
(1995)
Endocrinology
, vol.136
, Issue.8
, pp. 3585-3596
-
-
Kieffer, T.J.1
Mcintosh, C.H.S.2
Pederson, R.A.3
-
15
-
-
0036189831
-
The pharmacokinetics, pharmacodynamics, safety and tolerability of NN2211, a new long-acting GLP-1 derivative, in healthy men
-
Agersø H, Jensen LB, Elbrønd B, Rolan P, Zdravkovic M. The pharmacokinetics, pharmacodynamics, safety and tolerability of NN2211, a new long-acting GLP-1 derivative, in healthy men. Diabetologia 2002; 45(2): 195-202.
-
(2002)
Diabetologia
, vol.45
, Issue.2
, pp. 195-202
-
-
Agersø, H.1
Jensen, L.B.2
Elbrønd, B.3
Rolan, P.4
Zdravkovic, M.5
-
16
-
-
33745276226
-
An open-label, parallel group study investigating the effects of age and gender on the pharmacokinetics of the once daily glucagon-like peptide-1 analogue liraglutide
-
Damholt B, Golor G, Wierich W, Pederson P, Ekblom M, Zdravkovic M. An open-label, parallel group study investigating the effects of age and gender on the pharmacokinetics of the once daily glucagon-like peptide-1 analogue liraglutide. J Clin Pharmacol 2006; 46(6): 635-641.
-
(2006)
J Clin Pharmacol
, vol.46
, Issue.6
, pp. 635-641
-
-
Damholt, B.1
Golor, G.2
Wierich, W.3
Pederson, P.4
Ekblom, M.5
Zdravkovic, M.6
-
17
-
-
39749143348
-
Liraglutide, a once-daily human GLP-1 analogue, improves pancreatic B-cell function and arginine-stimulated insulin secretion during hyperglycaemia in patients with Type 2 diabetes mellitus
-
Vilsbøll T, Brock B, Perrild H, et al. Liraglutide, a once-daily human GLP-1 analogue, improves pancreatic B-cell function and arginine-stimulated insulin secretion during hyperglycaemia in patients with Type 2 diabetes mellitus. Diabet Med 2008; 25(2): 152-156.
-
(2008)
Diabet Med
, vol.25
, Issue.2
, pp. 152-156
-
-
Vilsbøll, T.1
Brock, B.2
Perrild, H.3
-
18
-
-
4344708602
-
No impairment of hypoglycemia counterregulation via glucagon with NN2211, a GLP-1 derivative, in subjects with type 2-diabetes
-
Nauck MA, El-Ouaghlidi A, Hompesch M, Jacobsen J, Elbrond B. No impairment of hypoglycemia counterregulation via glucagon with NN2211, a GLP-1 derivative, in subjects with type 2-diabetes. Diabetes 2008; 52 (Suppl 1): A128.
-
(2008)
Diabetes
, vol.52
, Issue.SUPPL. 1
-
-
Nauck, M.A.1
El-Ouaghlidi, A.2
Hompesch, M.3
Jacobsen, J.4
Elbrond, B.5
-
19
-
-
57649231326
-
The molecular basis for the delayed absorption of the once-daily human GLP-1 analogue, liraglutide
-
Steensgaard DB, Thomsen JK, Olsen HB, Knudsen LB. The molecular basis for the delayed absorption of the once-daily human GLP-1 analogue, liraglutide. Diabetes 2008; 57 (Suppl 1): A164.
-
(2008)
Diabetes
, vol.57
, Issue.SUPPL. 1
-
-
Steensgaard, D.B.1
Thomsen, J.K.2
Olsen, H.B.3
Knudsen, L.B.4
-
20
-
-
0038353630
-
The GLP-1 derivative NN2211 restores beta-cell sensitivity to glucose in type 2 diabetic patients after a single dose
-
Chang AM, Jakobsen G, Sturis J, et al. The GLP-1 derivative NN2211 restores beta-cell sensitivity to glucose in type 2 diabetic patients after a single dose. Diabetes 2003; 52(7): 1786-1791.
-
(2003)
Diabetes
, vol.52
, Issue.7
, pp. 1786-1791
-
-
Chang, A.M.1
Jakobsen, G.2
Sturis, J.3
-
21
-
-
0034108646
-
Potent derivatives of glucagon-like peptide-1 with pharmacokinetic properties suitable for once daily administration
-
Knudsen LB, Nielsen PF, Huusfeldt PO, et al. Potent derivatives of glucagon-like peptide-1 with pharmacokinetic properties suitable for once daily administration. J Med Chem 2000; 43(9): 1664-1669.
-
(2000)
J Med Chem
, vol.43
, Issue.9
, pp. 1664-1669
-
-
Knudsen, L.B.1
Nielsen, P.F.2
Huusfeldt, P.O.3
-
22
-
-
2342599057
-
One week's treatment with the long-acting glucagon-like peptide 1 derivative liraglutide (NN2211) markedly improves 24-h glycemia and alpha- and beta-cell function and reduces endogenous glucose release in patients with type 2 diabetes
-
Degn KB, Juhl CB, Sturis J, et al. One week's treatment with the long-acting glucagon-like peptide 1 derivative liraglutide (NN2211) markedly improves 24-h glycemia and alpha- and beta-cell function and reduces endogenous glucose release in patients with type 2 diabetes. Diabetes 2004; 53(5): 1187-1194.
-
(2004)
Diabetes
, vol.53
, Issue.5
, pp. 1187-1194
-
-
Degn, K.B.1
Juhl, C.B.2
Sturis, J.3
-
23
-
-
56249086994
-
Liraglutide, a once-daily human GLP-1 analog, added to a sulfonylurea (SU) offers significantly better glycaemic control and favourable weight change compared with rosiglitazone and SU combination therapy in subjects with type 2 diabetes
-
Marre M, Shaw J, Brandle M, et al. Liraglutide, a once-daily human GLP-1 analog, added to a sulfonylurea (SU) offers significantly better glycaemic control and favourable weight change compared with rosiglitazone and SU combination therapy in subjects with type 2 diabetes. Diabetes 2008; 57 (Suppl 1): A4.
-
(2008)
Diabetes
, vol.57
, Issue.SUPPL. 1
-
-
Marre, M.1
Shaw, J.2
Brandle, M.3
-
24
-
-
62449169287
-
Efficacy and safety comparison of liraglutide, glimepiride, and placebo, all in combination with metformin in type 2 diabetes
-
For the LEAD-2 Metformin Study Group
-
Nauck M, Frid A, Hermansen K, et al. For the LEAD-2 Metformin Study Group. Efficacy and safety comparison of liraglutide, glimepiride, and placebo, all in combination with metformin in type 2 diabetes. Diabetes Care 2009; 32: 84-90.
-
(2009)
Diabetes Care
, vol.32
, pp. 84-90
-
-
Nauck, M.1
Frid, A.2
Hermansen, K.3
-
25
-
-
59449101432
-
Liraglutide versus glimepiride mono-therapy for type 2 diabetes (LEAD-3 Mono): A randomised, 52-week, phase III, double-blind, parallel treatment trial
-
For the LEAD-3 (Mono) Study Group
-
Garber A, Henry R, Ratner R, et al. For the LEAD-3 (Mono) Study Group. Liraglutide versus glimepiride mono-therapy for type 2 diabetes (LEAD-3 Mono): A randomised, 52-week, phase III, double-blind, parallel treatment trial. Lancet 2009; 373 (9962): 473-481.
-
(2009)
Lancet
, vol.373
, Issue.9962
, pp. 473-481
-
-
Garber, A.1
Henry, R.2
Ratner, R.3
-
26
-
-
57649239513
-
Effect of the GLP-1 analog liraglutide on glycaemic control and weight reduction in patients on metformin and rosiglitazone: A randomized double-blind placebo-controlled trial
-
Abst 107
-
Zinman B, Gerich J, Buse J, et al. Effect of the GLP-1 analog liraglutide on glycaemic control and weight reduction in patients on metformin and rosiglitazone: A randomized double-blind placebo-controlled trial. Can J Diabetes 2008; 32 (Suppl): Abst 107.
-
(2008)
Can J Diabetes
, vol.32
, Issue.SUPPL.
-
-
Zinman, B.1
Gerich, J.2
Buse, J.3
-
27
-
-
56249125773
-
Significantly better glycaemic control and weight reduction with liraglutide, a once-daily human GLP-1 analog, compared with insulin glargine: All as add-on to metformin and a sulfonylurea in type 2 diabetes
-
Russell-Jones D, Vaag A, Schmitz O, et al. Significantly better glycaemic control and weight reduction with liraglutide, a once-daily human GLP-1 analog, compared with insulin glargine: All as add-on to metformin and a sulfonylurea in type 2 diabetes. Diabetes 2008; 57 (Suppl 1): A159.
-
(2008)
Diabetes
, vol.57
, Issue.SUPPL. 1
-
-
Russell-Jones, D.1
Vaag, A.2
Schmitz, O.3
-
28
-
-
70349202215
-
-
US20090036381
-
Brand, S.J., Cruz, A., Pastrak, A., Hew, Y.: US20090036381 (2009).
-
(2009)
-
-
Brand, S.J.1
Cruz, A.2
Pastrak, A.3
Hew, Y.4
-
29
-
-
57649232757
-
Molecular, pharmacological and clinical aspects of liraglutide, a once-daily human GLP-1 analogue
-
Russell-Jones D. Molecular, pharmacological and clinical aspects of liraglutide, a once-daily human GLP-1 analogue. Mol Cell Endocrinol 2009; 297: 137-140.
-
(2009)
Mol Cell Endocrinol
, vol.297
, pp. 137-140
-
-
Russell-Jones, D.1
-
30
-
-
34249869806
-
Liraglutide significantly improves glycaemic control, and lowers body weight without risk of either major or minor hypoglycaemic episodes in subjects with Type 2 diabetes
-
Vilsbøll T, Zdravkovic M, Le-Thi T, et al. Liraglutide significantly improves glycaemic control, and lowers body weight without risk of either major or minor hypoglycaemic episodes in subjects with Type 2 diabetes. Diabetes Care 2007; 30: 1608-1610.
-
(2007)
Diabetes Care
, vol.30
, pp. 1608-1610
-
-
Vilsbøll, T.1
Zdravkovic, M.2
Le-Thi, T.3
-
31
-
-
70349192889
-
-
Meinke, P. T., Denker, A., Meininger, G.E., Uemura, N., Wagner, J.A., Charnick, S.: WO2008137105(2008).
-
Meinke, P. T., Denker, A., Meininger, G.E., Uemura, N., Wagner, J.A., Charnick, S.: WO2008137105(2008).
-
-
-
-
32
-
-
70349199107
-
-
Klein, T., Blaser, A., Rudolph, B., Kautz, U., Selige, J., Kromer, W.: WO2008028914A1(2008).
-
Klein, T., Blaser, A., Rudolph, B., Kautz, U., Selige, J., Kromer, W.: WO2008028914A1(2008).
-
-
-
|