Localization of antimicrobial peptides human β-defensins in minor salivary glands with Sjögren's syndrome

European Journal of Oral Sciences

Volumn 117, Issue 5, 2009, Pages 506-510

  Kaneda, Yoshihiro ^a   Yamaai, Tomoichiro ^b   Mizukawa, Nobuyoshi ^a   Nagatsuka, Hitoshi ^b   Yamachika, Eiki ^a   Gunduz, Mehmet ^b   Sawaki, Koichi ^c   Yamanishi, Yuji ^c   Matsubara, Masakazu ^a   Katase, Naoki ^b   Takagi, Shin ^a  

^a OKAYAMA UNIVERSITY   (Japan)

^b OKAYAMA UNIVERSITY   (Japan)

^c HIROSHIMA CITY HOSPITAL   (Japan)

Author keywords

Defensin; Minor salivary gland; Sj gren's syndrome

Indexed keywords

BETA DEFENSIN; BETA DEFENSIN 3, HUMAN; BETA-DEFENSIN 3, HUMAN; DEFB1 PROTEIN, HUMAN; DEFB4A PROTEIN, HUMAN;

ARTICLE; CLASSIFICATION; COMPARATIVE STUDY; DISEASE COURSE; EPITHELIUM CELL; FEMALE; HUMAN; IMMUNOHISTOCHEMISTRY; MALE; MIDDLE AGED; MINOR SALIVA GLAND; PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY; RHEUMATOID ARTHRITIS; SALIVA; SALIVARY GLAND DUCT; SECRETION; SJOEGREN SYNDROME;

ARTHRITIS, RHEUMATOID; BETA-DEFENSINS; DISEASE PROGRESSION; EPITHELIAL CELLS; FEMALE; HUMANS; IMMUNOHISTOCHEMISTRY; MALE; MIDDLE AGED; SALIVA; SALIVARY DUCTS; SALIVARY GLANDS, MINOR; SECRETORY RATE; SJOGREN'S SYNDROME;

EID: 70349202231     PISSN: 09098836     EISSN: 16000722     Source Type: Journal    
DOI: 10.1111/j.1600-0722.2009.00667.x     Document Type: Article

References (19)

1. Fox RI. Sjögren's syndrome. Lancet 2005 366 : 321 331.
2. Fox RI. Sjögren's syndrome: current therapies remain inadequate for a common disease. Expert Opin Investig Drugs 2000 9 : 2007 2016.
3. Vitali C, Bombardieri S, Jonsson R, Moutsopoulos HM, Alexander EL, Carsons SE, Daniels TE, Fox PC, Fox RI, Kassan SS, Pillemer SR, Talal N, Weisman MH. Classification criteria for Sjogren's syndrome: a revised version of the European criteria proposed by the American-European Consensus Group. Ann Rheum Dis 2002 61 : 554 558.
4. Fox RI, Liu AY. Sjogren's syndrome in dermatology. Clin Dermatol 2006 24 : 393 413.
5. Thomma BP, Cammue BP, Thevissen K. Plant defensins. Planta 2002 216 : 193 202.
6. Hoffmann JA, Hetru C. Insect defensins: inducible antibacterial peptides. Immunol Today 1992 13 : 411 415.
7. Cociancich S, Ghazi A, Hetru C, Hoffmann JA, Letellieeer L. Insect defensins, an inducible antibacterial peptide, forms voltage dependent channels in Micrococcus luteus. J Biol Chem 1993 268 : 19239 19245.
8. Lehrer RI, Ganz T, Selsted ME. Defensins: endogenous antibiotic peptides of animal cells. Cell 1991 64 : 229 230.
9. Ganz T. Defensins and host defense. Science 1999 286 : 420 421.
10. Mathews M, Jia HP, Guthmiller JM, Losh G, Graham S, Johnson GK, Tack BF, McCray PB Jr. Production of beta-defensin antimicrobial peptides by the oral mucosa and salivary glands. Infect Immun 1999 67 : 2740 2745.
11. Bonass WA, High AS, Owen PJ, Devine DA. Expression of beta-defensin genes by human salivary glands. Oral Microbiol Immunol 1999 14 : 371 374.
12. Abiko Y, Nishimura M, Kaku T. Defensins in saliva and the salivary glands. Med Electron Microsc 2003 36 : 247 252.
13. Sahasrabudhe KS, Kimball JR, Morton TH, Weinberg A, Dale BA. Expression of the antimicrobial peptide, human beta-defensin 1, in duct cells of minor salivary glands and detection in saliva. J Dent Res 2000 79 : 1669 1674.
14. Bals R, Wang X, Wu Z, Freeman T, Bafna V, Zasloff M, Wilson JM. Human beta-defensin 2 is a salt-sensitive peptide antibiotic expressed in human lung. J Clin Invest 1998 102 : 874 880. (Pubitemid 28419232)
15. Dunsche A, Acil Y, Siebert R, Harder J, Schroder JM, Jepsen S. Expression profile of human defensins and antimicrobial proteins in oral tissues. J Oral Pathol Med 2001 30 : 154 158.
16. Harder J, Bartels J, Christophers E, Schroder JM. Isolation and characterization of human beta-defensin-3, a novel human inducible peptide antibiotic. J Biol Chem 2001 276 : 5707 5713.
17. Dunsche A, Acil Y, Dommisch H, Siebert R, Schroder JM, Jepsen S. The novel human beta-defensin-3 is widely expressed in oral tissues. Eur J Oral Sci 2002 110 : 121 124.
18. Gotoh S, Watanabe Y, Fujibayashi T. Validity of stimulated whole saliva collection as a sialometric evaluation for diagnosing Sjögren's syndrome. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2005 99 : 299 302.
19. Konttinen YT, Kulomaa M, Malmström M, Kilpi A, Reitamo S. Lactoferrin in Sjögren's syndrome. Arthritis Rheum 1984 27 : 462 467.