Epstein-Barr virus prevalence in oral squamous cell cancer and in potentially malignant oral disorders in an eastern Hungarian population

European Journal of Oral Sciences

Volumn 117, Issue 5, 2009, Pages 536-540

  Kis, Andrea ^a   Fehér, Enikö ^a   Gáll, Tamás ^a   Tar, Ildikó ^b   Boda, Róbert ^b   Tóth, Etelka D ^b   Méhes, Gábor ^a   Gergely, Lajos ^a   Szarka, Krisztina ^a  

^a UNIVERSITY OF DEBRECEN   (Hungary)

^b UNIVERSITY OF DEBRECEN   (Hungary)

Author keywords

Aetiology; Oral leukoplakia; Oral lichen planus; Oral squamous cell cancer

Indexed keywords

EBV ASSOCIATED MEMBRANE ANTIGEN, EPSTEIN BARR VIRUS; EBV-ASSOCIATED MEMBRANE ANTIGEN, EPSTEIN-BARR VIRUS; MATRIX PROTEIN; ONCOPROTEIN; VIRUS ANTIGEN;

ADULT; AGE; AGED; ARTICLE; CASE CONTROL STUDY; COMPARATIVE STUDY; EPSTEIN BARR VIRUS; EPSTEIN BARR VIRUS INFECTION; FEMALE; HUMAN; HUNGARY; IMMUNOLOGY; ISOLATION AND PURIFICATION; LEUKOPLAKIA; LICHEN PLANUS; MALE; MIDDLE AGED; MOUTH MUCOSA; MOUTH TUMOR; PRECANCER; RISK FACTOR; SQUAMOUS CELL CARCINOMA; VIROLOGY; VIRUS CAPSID; VIRUS LOAD;

ADULT; AGE FACTORS; AGED; AGED, 80 AND OVER; ANTIGENS, VIRAL; CAPSID; CARCINOMA, SQUAMOUS CELL; CASE-CONTROL STUDIES; EPSTEIN-BARR VIRUS INFECTIONS; FEMALE; HERPESVIRUS 4, HUMAN; HUMANS; HUNGARY; LEUKOPLAKIA, ORAL; LICHEN PLANUS, ORAL; MALE; MIDDLE AGED; MOUTH MUCOSA; MOUTH NEOPLASMS; ONCOGENE PROTEINS, VIRAL; PRECANCEROUS CONDITIONS; RISK FACTORS; VIRAL LOAD; VIRAL MATRIX PROTEINS; YOUNG ADULT;

EID: 70349200794     PISSN: 09098836     EISSN: 16000722     Source Type: Journal    
DOI: 10.1111/j.1600-0722.2009.00660.x     Document Type: Article

References (27)

1. Macsween KF, Crawford D. Epstein-Barr virus - recent advantages. Lancet Infect Dis 2003 3 : 131 140.
2. Slots J, Saygun I, Sabeti M, Kubar A. Epstein-Barr virus in oral diseases. J Periodont Res 2006 41 : 235 244.
3. Bornkamm GW, Hammerschmidt W. Molecular virology of Epstein-Barr virus. Philos Trans R Soc Lond B 2001 356 : 437 459.
4. Raab-Traub N. Epstein-Barr virus in the pathogenesis of NPC. Semin Cancer Biol 2002 12 : 431 441.
5. Cohen JI. The biology of Epstein-Barr virus: lessons learned from the virus and the host. Curr Opin Immunol 1999 11 : 365 370.
6. Goldenberg D, Golz A, Netzer A, Rosenblatt E, Rachmiel A, Goldenberg RF, Joachims HZ. Epstein-Barr virus and cancers of the head and neck. Am J Otolaryngol 2001 22 : 197 205.
7. Horiuchi K, Mishima K, Ichijima K, Sugimura M, Ishida T, Kirita T. Epstein-Barr virus in the proliferative diseases of squamous epithelium in the oral cavity. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 1995 79 : 57 63.
8. Sand LP, Jalouli J, Larsson PA, Hirsch JM. Prevalence of Epstein-Barr virus in oral squamous cell carcinoma, oral lichen planus, and normal mucosa. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2002 93 : 586 592.
9. Higa M, Kinjo T, Kamiyama K, Iwamasa T, Hamada T, Iyama K. Epstein-Barr virus (EBV) subtype in EBV related oral squamous cell carcinoma in Okinawa, a subtropical island in southern Japan, compared with Kitakyushu and Kumamoto in mainland Japan. J Clin Pathol 2002 55 : 414 423.
10. Higa M, Kinjo T, Kamiyama K, Chinen K, Iwasama T, Arasaki A, Sunakawa H. Epstein-Barr virus (EBV)-related oral squamous cell carcinoma in Okinawa, a subtropical island, in southern Japan - simultaneously infected with human papillomavirus (HPV). Oral Oncol 2003 39 : 405 414.
11. Shamaa AA, Zyada MM, Wagner M, Awad SS, Osman MM, Abdel Azeem AA. The significance of Epstein-Barr virus (EBV) and DNA topoisomerase II alpha (DNA-Topo II alpha) immunoreactivity in normal oral mucosa, oral epithelial dysplasia (OED) and oral squamous cell carcinoma (OSCC). Diagn Pathol 2008 3 : 45.
12. Gonzalez-Moles MA, Gutierrez J, Rodriguez MJ, Ruiz-Avila I, Rodriguez-Archilla A. Epstein-Barr virus latent membrane protein-1 (LMP-1) expression in oral squamous cell carcinoma. Laryngoscope 2002 112 : 482 487.
13. Mao EJ, Smith CJ. Detection of Epstein-Barr virus (EBV) DNA by the polymerase chain reaction (PCR) in oral smears from healthy individuals and patients with squamous cell carcinoma. J Oral Pathol Med 1993 22 : 12 17.
14. Cruz I, Van Den Brule A, Brink A, Snijders P, Walboomers J, Van Der Waal I, Meijer C. No direct role for Epstein-Barr virus in oral carcinogenesis: a study at the DNA, RNA and protein levels. Int J Cancer 2000 86 : 356 361.
15. Goldenberg D, Benoit NE, Begum S, Westra WH, Cohen Y, Koch WM, Sidransky D, Califano JA. Epstein-Barr virus in head and neck cancer assessed by quantitative polymerase chain reaction. Laryngoscope 2004 114 : 1027 1031.
16. Germán P, Beck Z, Semsei I, Kiss S, Görög B, Balogh E, D Tóth F, Nemes Z, Pajor L, Oláh É. Study of pathogenetic role of Epstein-Barr virus in Hungarian patients with B-cell non-Hodgkin lymphomas. Orv Hetil 2002 143 : 2619 2624. (Article in Hungarian)
17. Atula S, Auvinen E, Grenman R, Syrjanen S. Human papillomavirus and Epstein-Barr virus in epithelial carcinomas of the head and neck region. Anticancer Res 1997 17 : 4427 4433.
18. Kobayashi I, Shima K, Saito I, Kiyoshima T, Matsuo K, Ozeki S, Ohishi M, Sakai H. Prevalence of Epstein-Barr virus in oral squamous cell carcinoma. J Pathol 1999 189 : 34 39.
19. Cruz I, Van Den Brule AJ, Steenbergen RD, Snijders PJ, Meijer CJ, Walboomers JM, Snow GB, Van Der Waal I. Prevalence of Epstein-Barr virus in oral squamous cell carcinomas, premalignant lesions and normal mucosa - a study using the polymerase chain reaction. Oral Oncol 1997 33 : 182 188.
20. Ismail SB, Kumar SKS, Zain RB. Oral lichen planus and lichenoid reactions: etiopathogenesis, diagnosis, management and malignant transformation. J Oral Sci 2007 49 : 89 106.
21. Mithani SK, Mydlarz WK, Grumbine FL, Smith IM, Califano JA. Molecular genetics of premalignant oral lesions. Oral Dis 2007 13 : 126 133.
22. Gonzalez-Moles MA, Scully C, Gil-Montoya JA. Oral lichen planus: controversies surrounding malignant transformation. Oral Dis 2008 14 : 229 243.
23. Neville BW, Day TA. Oral cancer and precancerous lesions. CA Cancer J Clin 2002 52 : 195 215.
24. Napier SS, Speight PM. Natural history of potentially malignant oral lesions and conditions: an overview of the literature. J Oral Pathol Med 2008 37 : 1 10.
25. De Sousa FA, Rosa LE. Oral lichen planus: clinical and histopathological considerations. Rev Bras Otorrinolaringol 2008 74 : 284 292.
26. Van Rensburg EJ, Engelbrecht S, Van Heerden W, Raubenheimer E, Schoub BD. Detection of EBV DNA in oral squamous cell carcinomas in a black African population sample. In Vivo 1995 9 : 199 202.
27. Crawford DH. Biology and disease associations of Epstein-Barr virus. Philos Trans R Soc Lond B 2001 356 : 461 473.