Synthesis and antiprotozoal properties of pentamidine congeners bearing the benzofuran motif

Journal of Medicinal Chemistry

Volumn 52, Issue 18, 2009, Pages 5763-5767

  Bakunov, Stanislav A ^a   Bakunova, Svetlana M ^a   Bridges, Arlene S ^a   Wenzler, Tanja ^c   Barszcz, Todd ^b   Werbovetz, Karl A ^b   Brun, Reto ^c   Tidwell, Richard R ^a  

^a UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^b OHIO STATE UNIVERSITY   (United States)

^c SWISS TROPICAL AND PUBLIC HEALTH INSTITUTE   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

2 [3 [3 (4 CARBAMIMIDOYLPHENOXY)PROPOXY]PHENYL]BENZOFURAN 5 CARBOXAMIDINE; 2 IODOPHENOL DERIVATIVE; ANTILEISHMANIAL AGENT; ANTIMALARIAL AGENT; ANTITRYPANOSOMAL AGENT; AROMATIC COMPOUND; BENZOFURAN DERIVATIVE; CARBON; COPPER; PENTAMIDINE DERIVATIVE; PHENOL DERIVATIVE; PHENYLACETYLENE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANNULATION REACTION; ANTIMALARIAL ACTIVITY; ANTIPROTOZOAL ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG SELECTIVITY; DRUG SYNTHESIS; IC 50; LEISHMANIA DONOVANI; MOUSE; NONHUMAN; PLASMODIUM FALCIPARUM; STRUCTURE ACTIVITY RELATION; TRYPANOSOMA RHODESIENSE; TRYPANOSOMIASIS;

ANIMALS; ANTIPROTOZOAL AGENTS; BENZOFURANS; CELL LINE; LEISHMANIA DONOVANI; PENTAMIDINE; PLASMODIUM FALCIPARUM; RATS; STRUCTURE-ACTIVITY RELATIONSHIP; TRYPANOSOMA BRUCEI RHODESIENSE;

EID: 70349192881     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm9006406     Document Type: Article

References (14)

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