Activating Autoantibodies to the Beta-1 Adrenergic and M2 Muscarinic Receptors Facilitate Atrial Fibrillation in Patients With Graves' Hyperthyroidism

Journal of the American College of Cardiology

Volumn 54, Issue 14, 2009, Pages 1309-1316

  Stavrakis, Stavros ^a   Yu, Xichun ^a   Patterson, Eugene ^a,b   Huang, Shijun ^a   Hamlett, Sean R ^a   Chalmers, Laura ^a   Pappy, Reji ^a   Cunningham, Madeleine W ^b   Morshed, Syed A ^c   Davies, Terry F ^c   Lazzara, Ralph ^a   Kem, David C ^a  

^a UNIVERSITY OF OKLAHOMA HEALTH SCIENCES CENTER   (United States)

^b UNIVERSITY OF OKLAHOMA COLLEGE OF MEDICINE   (United States)

^c VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

adrenergic receptors; activating autoantibodies; atrial fibrillation; Graves' hyperthyroidism; M2 muscarinic receptor

Indexed keywords

ATROPINE; AUTOANTIBODY; BETA 1 ADRENERGIC RECEPTOR; IMMUNOGLOBULIN G; MUSCARINIC M2 RECEPTOR; NADOLOL; THYROTROPIN RECEPTOR ANTIBODY;

ACTION POTENTIAL; ADULT; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; AUTONOMIC NERVE; CHO CELL; CONTROLLED STUDY; CROSS REACTION; DOG; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; FLOW CYTOMETRY; GRAVES DISEASE; HEART ATRIUM FIBRILLATION; HUMAN; INTRACELLULAR RECORDING; MAJOR CLINICAL STUDY; MALE; NERVE STIMULATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PULMONARY VEIN; PURKINJE FIBER; SINUS RHYTHM;

ANIMALS; ANTI-ARRHYTHMIA AGENTS; ATRIAL FIBRILLATION; ATROPINE; AUTOANTIBODIES; CASE-CONTROL STUDIES; CRICETINAE; DOGS; FEMALE; GRAVES DISEASE; HUMANS; IMMUNOGLOBULIN G; MALE; MIDDLE AGED; MYOCARDIAL CONTRACTION; PURKINJE FIBERS; RECEPTOR, MUSCARINIC M2; RECEPTORS, ADRENERGIC, BETA-1;

EID: 70349171593     PISSN: 07351097     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jacc.2009.07.015     Document Type: Article

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