A new strategy to destroy antibiotic resistant microorganisms: Antimicrobial photodynamic treatment

Mini-Reviews in Medicinal Chemistry

Volumn 9, Issue 8, 2009, Pages 974-983

  Maisch, Tim ^a  

^a UNIVERSITY HOSPITAL REGENSBURG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

5,10,15,20 TETRAKIS (4 N METHYLPYRIDIYL)PORPHIN; 5,10,15,20 TRIS [4 (3 N,N,N TRIMETHYLAMMONIUMPROPOXY)PHENYL] 20 (4 TRIFLUOROMETHYLPHENYL)PORPHIN IODIDE; ANTIBIOTIC AGENT; FULLERENE; FUROCOUMARIN; HEMATOPORPHYRIN; METHYLENE BLUE; PHENOTHIAZINE; PHOTOSENSITIZING AGENT; PHTHALOCYANINE DERIVATIVE; POLYETHYLENEIMINE; POLYLYSINE; PORPHYRIN; PSORALEN; REACTIVE OXYGEN METABOLITE; TIN CHLORIDE; TOLONIUM CHLORIDE; UNCLASSIFIED DRUG;

ACNE VULGARIS; ANTIBIOTIC RESISTANCE; ANTIMICROBIAL ACTIVITY; BACILLUS CEREUS; BACTERIOPHAGE; BRAIN ABSCESS; CLINICAL TRIAL; DRUG STRUCTURE; ENTEROCOCCUS FAECALIS; ESCHERICHIA COLI; GRAM NEGATIVE BACTERIUM; GRAM POSITIVE BACTERIUM; HUMAN; ILLUMINATION; LIGHT ABSORPTION; NONHUMAN; PERIODONTITIS; PHOTODYNAMIC THERAPY; PHOTOSENSITIZATION; PHYSICAL CHEMISTRY; PSEUDOMONAS AERUGINOSA; QUANTUM YIELD; REVIEW; SKIN INFECTION; STAPHYLOCOCCUS AUREUS;

EID: 70349125486     PISSN: 13895575     EISSN: None     Source Type: Journal    
DOI: 10.2174/138955709788681582     Document Type: Review

References (76)

1. Livermore, D.M. Antibiotic resistance in staphylococci. Int. J. Antimicrob. Agents., 2000, 16(Suppl 1), S3-10.
2. Hiramatsu, K.; Hanaki, H.; Ino, T.; Yabuta, K.; Oguri, T.; Tenover, F.C. Methicillin-resistant Staphylococcus aureus clinical strain with reduced vancomycin susceptibility. J. Antimicrob. Chemother., 1997, 40(1), 135-6.
3. Smith, T.L.; Pearson, M.L.; Wilcox, K.R.; Cruz, C.; Lancaster, M.V.; Robinson-Dunn, B.; Tenover, F.C.; Zervos, M.J.; Band, J.D.; White, E.; Jarvis, W.R. Emergence of vancomycin resistance in Staphylococcus aureus. Glycopeptide-Intermediate Staphylococcus aureus Working Group. N. Engl. J. Med., 1999, 340(7), 493-501.
4. Fridkin, S.K. Vancomycin-intermediate and -resistant Staphylococcus aureus: what the infectious disease specialist needs to know. Clin. Infect. Dis., 2001, 32(1), 108-15.
5. Sievert, D.; Boulton, M.; Stoltman, G.; Johnson, D.; Stobierski, M.; Downes, F.; Somsel, P.; Rudrik, J.; Brown, W.; Hafeez, W.; Lundstrom, T.; Flanagan, E.; Johnson, R.; Mitchell, J.; Chang, S. Staphylococcus aureus Resistant to Vancomycin. Morb. Mortal. Wkly. Rep., 2002, 51(26), 565-567.
6. Al-Rawahi, G.N.; Reynolds, S.; Porter, S.D.; Forrester, L.; Kishi, L.; Chong, T.; Bowie, W.R.; Doyle, P.W. Community-associated CMRSA-10 (USA-300) is the predominant strain among methicillin-resistant Staphylococcus aureus strains causing skin and soft tissue infections in patients presenting to the emergency department of a canadian tertiary care hospital. J. Emerg. Med., 2008.
7. Witte, W.; Braulke, C.; Cuny, C.; Strommenger, B.; Werner, G.; Heuck, D.; Jappe, U.; Wendt, C.; Linde, H.J.; Harmsen, D. Emergence of methicillin-resistant Staphylococcus aureus with Panton-Valentine leukocidin genes in central Europe. Eur. J. Clin. Microbiol. Infect. Dis., 2005, 24(1), 1-5.
8. Poole, K. Efflux pumps as antimicrobial resistance mechanisms. Ann. Med., 2007, 39(3), 162-76.
9. McDermott, P.F.; Walker, R.D.; White, D.G. Antimicrobials: modes of action and mechanisms of resistance. Int. J. Toxicol., 2003, 22(2), 135-43.
10. Wright, G.D. Mechanisms of resistance to antibiotics. Curr. Opin. Chem. Biol., 2003, 7(5), 563-9.
11. Dougherty, T.J.; Gomer, C.J.; Henderson, B.W.; Jori, G.; Kessel, D.; Korbelik, M.; Moan, J.; Peng, Q. Photodynamic therapy. J. Natl. Cancer Inst., 1998, 90(12), 889-905.
12. Wainwright, M. Photodynamic antimicrobial chemotherapy (PACT). J. Antimicrob. Chemother., 1998, 42(1), 13-28.
13. Hamblin, M.R.; Hasan, T. Photodynamic therapy: a new antimicrobial approach to infectious disease? Photochem. Photobiol. Sci., 2004, 3(5), 436-50.
14. Maisch, T.; Szeimies, R.M.; Jori, G.; Abels, C. Antibacterial photodynamic therapy in dermatology. Photochem. Photobiol. Sci., 2004, 3(10), 907-17.
15. Vakrat-Haglili, Y.; Weiner, L.; Brumfeld, V.; Brandis, A.; Salomon, Y.; McLlroy, B.; Wilson, B.C.; Pawlak, A.; Rozanowska, M.; Sarna, T.; Scherz, A. The microenvironment effect on the generation of reactive oxygen species by Pd-bacteriopheophorbide. J. Am. Chem. Soc., 2005, 127(17), 6487-97.
16. Tanielian, C.; Schweitzer, C.; Mechin, R.; Wolff, C. Quantum yield of singlet oxygen production by monomeric and aggregated forms of hematoporphyrin derivative. Free Radic. Biol. Med., 2001, 30(2), 208-12.
17. Engl, R.; Kilger R.; Maier, M.; Scherer, K.; Abels, C.; Baeumler, W. Singlet oxygen generation by 8-methoxypsoralen in deuterium oxide: relaxation rate constants and dependence of the generation efficacy on the oxygen partial pressure. J. Phys. Chem. B., 2002, 1006, 5776-5781.
18. Baier, J.; Maisch, T.; Regensburger, J.; Loibl, M.; Vasold, R.; Baeumler, W. Time dependence of singlet oxygen luminescence provides an indication of oxygen concentration during oxygen consumption. J. Biomed. Opt., 2007, 12(6), 064008.
19. Aveline, B. in Comprehensive Series in Photoscience, 2001; Vol. 2, p. 17-34.
20. Schafer, M.; Schmitz, C.; Horneck, G. High sensitivity of Deinococcus radiodurans to photodynamically-produced singlet oxygen. Int. J. Radiat. Biol., 1998, 74(2), 249-53.
21. Merchat, M.; Bertolini, G.; Giacomini, P.; Villanueva, A.; Jori, G. Meso-substituted cationic porphyrins as efficient photosensitizers of gram-positive and gram-negative bacteria. J. Photochem. Photobiol. B., 1996, 32(3), 153-7.
22. Nitzan, Y.; Dror, R.; Ladan, H.; Malik, Z.; Kimel, S.; Gottfried, V. Structure-activity relationship of porphines for photoinactivation of bacteria. Photochem. Photobiol., 1995, 62(2), 342-7.
23. Minnock, A.; Vernon, D.I.; Schofield, J.; Griffiths, J.; Parish, J.H.; Brown, S.T. Photoinactivation of bacteria. Use of a cationic watersoluble zinc phthalocyanine to photoinactivate both gram-negative and gram-positive bacteria. J. Photochem. Photobiol. B., 1996, 32(3), 159-64.
24. Reddi, E.; Ceccon, M.; Valduga, G.; Jori, G.; Bommer, J.C.; Elisei, F.; Latterini, L.; Mazzucato, U. Photophysical properties and antibacterial activity of meso-substituted cationic porphyrins. Photochem. Photobiol., 2002, 75(5), 462-70.
25. Menezes, S.; Capella, M.A.; Caldas, L.R. Photodynamic action of methylene blue: repair and mutation in Escherichia coli. J. Photochem. Photobiol. B., 1990, 5(3-4), 505-17.
26. Dobson, J.; Wilson, M. Sensitization of oral bacteria in biofilms to killing by light from a low-power laser. Arch. Oral. Biol., 1992, 37(11), 883-7.
27. Wainwright, M.; Phoenix, D.A.; Marland, J.; Wareing, D.R.; Bolton, F.J. A study of photobactericidal activity in the phenothiazinium series. FEMS Immunol. Med. Microbiol., 1997, 19(1), 75-80.
28. Wainwright, M.; Phoenix, D.A.; Laycock, S.L.; Wareing, D.R.; Wright, P.A. Photobactericidal activity of phenothiazinium dyes against methicillin-resistant strains of Staphylococcus aureus. FEMS Microbiol. Lett., 1998, 160(2), 177-81.
29. Pal, M.K.; Ghosh, T.C.; Ghosh, J.K. Studies on the conformation of and metal ion binding by teichoic acid of Staphylococcus aureus. Biopolymers, 1990, 30(3-4), 273-7.
30. O'Neill, J.F.; Hope, C.K.; Wilson, M. Oral bacteria in multi-species biofilms can be killed by red light in the presence of toluidine blue. Lasers Surg. Med., 2002, 31(2), 86-90.
31. Maisch, T.; Bosl, C.; Szeimies, R.M.; Lehn, N.; Abels, C. Photodynamic effects of novel XF porphyrin derivatives on prokaryotic and eukaryotic cells. Antimicrob. Agents. Chemother., 2005, 49(4), 1542-52.
32. Nitzan, Y.; Gutterman, M.; Malik, Z.; Ehrenberg, B. Inactivation of gram-negative bacteria by photosensitized porphyrins. Photochem. Photobiol., 1992, 55(1), 89-96.
33. Caminos, D.A.; Spesia, M.B.; Durantini, E.N. Photodynamic inactivation of Escherichia coli by novel meso-substituted porphyrins by 4-(3-N,N,N-trimethylammoniumpropoxy)phenyl and 4-(trifluoromethyl)phenyl groups. Photochem. Photobiol. Sci., 2006, 5(1), 56-65.
34. Merchat, M.; Spikes, J.D.; Bertoloni, G.; Jori, G. Studies on the mechanism of bacteria photosensitization by meso-substituted cationic porphyrins. J. Photochem. Photobiol. B., 1996, 35(3), 149-57.
35. Nikaido, H.; Vaara, M. Molecular basis of bacterial outer membrane permeability. Microbiol. Rev., 1985, 49(1), 1-32.
36. Caminos, D.A.; Spesia, M.B.; Pons, P.; Durantini, E.N. Mechanisms of Escherichia coli photodynamic inactivation by an amphiphilic tricationic porphyrin and 5,10,15,20-tetra(4-N,N,Ntrimethylammoniumphenyl) porphyrin. Photochem. Photobiol. Sci., 2008, 7(9), 1071-8.
37. Caminos, D.A.; Durantini, E.N. Photodynamic inactivation of Escherichia coli immobilized on agar surfaces by a tricationic porphyrin. Bioorg. Med. Chem., 2006, 14(12), 4253-9.
38. Kroto, H.W.; Heath, J.R.; O'Brien, S.C.; Curl, R.F.; Smalley, R.E. C60: Buckministerfulleren. Nature, 1985, 318, 162-163.
39. Jensen, A.W.; Wilson, S.R.; Schuster, D.I. Biological applications of fullerenes. Bioorg. Med. Chem., 1996, 4(6), 767-79.
40. Tagmatarchis, N.; Shinohara, H. Fullerenes in medicinal chemistry and their biological applications. Mini. Rev. Med. Chem., 2001, 1(4), 339-48.
41. Tegos, G.P.; Demidova, T.N.; Arcila-Lopez, D.; Lee, H.; Wharton, T.; Gali, H.; Hamblin, M.R. Cationic fullerenes are effective and selective antimicrobial photosensitizers. Chem. Biol., 2005, 12(10), 1127-35.
42. Berenbaum, M. Toxicity of a Furanocoumarin to Armyworms: A Case of Biosynthetic Escape from Insect Herbivores. Science, 1978, 201(4355), 532-534.
43. Miller, S.S.; Eisenstadt, E. Enhanced sensitivity of Escherichia coli umuC to photodynamic inactivation by angelicin (isopsoralen). J. Bacteriol., 1985, 162(3), 1307-10.
44. Margolis-Nunno, H.; Robinson, R.; Horowitz, B.; Geacintov, N.E.; Ben-Hur, E. Psoralen-mediated virus photoinactivation in platelet concentrates: enhanced specificity of virus kill in the absence of shorter UVA wavelengths. Photochem. Photobiol., 1995, 62(5), 917-22.
45. Berthiaume, F.; Reiken, S.R.; Toner, M.; Tompkins, R.G.; Yarmush, M.L. Antibody-targeted photolysis of bacteria in vivo. Biotechnology (N Y), 1994, 12(7), 703-6.
46. Hamblin, M.R.; O'Donnell, D.A.; Murthy, N.; Contag, C.H.; Hasan, T. Rapid control of wound infections by targeted photodynamic therapy monitored by in vivo bioluminescence imaging. Photochem. Photobiol., 2002, 75(1), 51-7.
47. Teichert, M.C.; Jones, J.W.; Usacheva, M.N.; Biel, M.A. Treatment of oral candidiasis with methylene blue-mediated photodynamic therapy in an immunodeficient murine model. Oral. Surg. Oral. Med. Oral. Pathol. Oral. Radiol. Endod., 2002, 93(2), 155-60.
48. Tegos, G.P.; Anbe, M.; Yang, C.; Demidova, T.N.; Satti, M.; Mroz, P.; Janjua, S.; Gad, F.; Hamblin, M.R. Protease-stable polycationic photosensitizer conjugates between polyethyleneimine and chlorin(e6) for broad-spectrum antimicrobial photoinactivation. Antimicrob. Agents. Chemother., 2006, 50(4), 1402-10.
49. Bhatti, M.; MacRobert, A.; Meghji, S.; Henderson, B.; Wilson, M. A study of the uptake of toluidine blue O by Porphyromonas gingivalis and the mechanism of lethal photosensitization. Photochem. Photobiol., 1998, 68(3), 370-6.
50. Soukos, N.S.; Crowley, K.; Bamberg, M.P.; Gillies, R.; Doukas, A.G.; Evans, R.; Kollias, N. A rapid method to detect dried saliva stains swabbed from human skin using fluorescence spectroscopy. Forensic. Sci. Int., 2000, 114(3), 133-8.
51. Wood, S.; Nattress, B.; Kirkham, J.; Shore, R.; Brookes, S.; Griffiths, J.; Robinson, C. An in vitro study of the use of photodynamic therapy for the treatment of natural oral plaque biofilms formed in vivo. J. Photochem. Photobiol. B., 1999, 50(1), 1-7.
52. Robinson, C.; Strafford, S.; Rees, G.; Brookes, S.J.; Kirkham, J.; Shore, R.C.; Watson, P.S.; Wood, S. Plaque biofilms: the effect of chemical environment on natural human plaque biofilm architecture. Arch. Oral. Biol., 2006, 51(11), 1006-14.
53. Wood, S.; Metcalf, D.; Devine, D.; Robinson, C. Erythrosine is a potential photosensitizer for the photodynamic therapy of oral plaque biofilms. J. Antimicrob. Chemother., 2006, 57(4), 680-4.
54. Pratten, J.; Andrews, C.S.; Craig, D.Q.; Wilson, M. Structural studies of microcosm dental plaques grown under different nutritional conditions. FEMS Microbiol. Lett., 2000, 189(2), 215-8.
55. Pratten, J.; Bedi, R.; Wilson, M. An in vitro study of the effect of fluoridated milk on oral bacterial biofilms. Appl. Environ. Microbiol., 2000, 66(4), 1720-3.
56. Zanin, I.C.; Goncalves, R.B.; Junior, A.B.; Hope, C.K.; Pratten, J. Susceptibility of Streptococcus mutans biofilms to photodynamic therapy: an in vitro study. J. Antimicrob. Chemother., 2005, 56(2), 324-30.
57. Konopka, K.; Goslinski, T. Photodynamic therapy in dentistry. J. Dent. Res., 2007, 86(8), 694-707.
58. de Oliveira, R.R.; Schwartz-Filho, H.O.; Novaes, A.B., Jr.; Taba, M., Jr. Antimicrobial photodynamic therapy in the non-surgical treatment of aggressive periodontitis: a preliminary randomized controlled clinical study. J. Periodontol., 2007, 78(6), 965-73.
59. Laws, E.R. Phototherapy of brain tumors. Photodynamic therapy of tumours and other diseasesq, Jori, G.; Perria, C.A. Eds. Padova: Edizioni Libreria Progetto, 1985.
60. Dierickx, C.C.; Goldenhersh, M.; Dwyer, P.; Stratigos, A.; Mihm, M.; Anderson, R.R. Photodynamic therapy for nevus sebaceus with topical delta-aminolevulinic acid. Arch. Dermatol., 1999, 135(6), 637-40.
61. Itoh, Y.; Ninomiya, Y.; Tajima, S.; Ishibashi, A. Photodynamic therapy of acne vulgaris with topical delta-aminolaevulinic acid and incoherent light in Japanese patients. Br. J. Dermatol., 2001, 144(3), 575-9.
62. Ashkenazi, H.; Malik, Z.; Harth, Y.; Nitzan, Y. Eradication of Propionibacterium acnes by its endogenic porphyrins after illumination with high intensity blue light. FEMS Immunol. Med. Microbiol., 2003, 35(1), 17-24.
63. Embleton, M.L.; Nair, S.P.; Cookson, B.D.; Wilson, M.: Selective lethal photosensitization of methicillin-resistant Staphylococcus aureus using an IgG-tin (IV) chlorin e6 conjugate. J. Antimicrob. Chemother., 2002, 50(6), 857-64.
64. Roberts, J.I.; Gaston, M.A. Protein A and coagulase expression in epidemic and non-epidemic Staphylococcus aureus. J. Clin. Pathol., 1987, 40(8), 837-40.
65. Embleton, M.L.; Nair, S.P.; Heywood, W.; Menon, D.C.; Cookson, B.D.; Wilson, M. Development of a novel targeting system for lethal photosensitization of antibiotic-resistant strains of Staphylococcus aureus. Antimicrob. Agents. Chemother., 2005, 49(9), 3690-6.
66. van Gemert, M.J.; Jacques, S.L.; Sterenborg, H.J.; Star, W.M. Skin optics. IEEE. Trans. Biomed. Eng., 1989, 36(12), 1146-54.
67. Baeumler, W. in Comprehensive Series in Photoscience. Elsevier, 2001; Vol. 2, pp. 83-98.
68. Poole, K. Efflux-mediated antimicrobial resistance. J. Antimicrob. Chemother., 2005, 56(1), 20-51.
69. Tegos, G.P.; Hamblin, M.R. Phenothiazinium antimicrobial photosensitizers are substrates of bacterial multidrug resistance pumps. Antimicrob. Agents. Chemother., 2006, 50(1), 196-203.
70. Dortbudak, O.; Haas, R.; Bernhart, T.; Mailath-Pokorny, G. Lethal photosensitization for decontamination of implant surfaces in the treatment of peri-implantitis. Clin. Oral. Implants. Res., 2001, 12(2), 104-8.
71. Haas, R.; Dortbudak, O.; Mensdorff-Pouilly, N.; Mailath, G. Elimination of bacteria on different implant surfaces through photosensitization and soft laser. An in vitro study. Clin. Oral. Implants. Res., 1997, 8(4), 249-54.
72. Shibli, J.A.; Martins, M.C.; Ribeiro, F.S.; Garcia, V.G.; Nociti, F.H., Jr.; Marcantonio, E., Jr. Lethal photosensitization and guided bone regeneration in treatment of peri-implantitis: an experimental study in dogs. Clin. Oral. Implants. Res., 2006, 17(3), 273-81.
73. Shibli, J.A.; Martins, M.C.; Theodoro, L.H.; Lotufo, R.F.; Garcia, V.G.; Marcantonio, E.J. Lethal photosensitization in microbiological treatment of ligature-induced peri-implantitis: a preliminary study in dogs. J. Oral. Sci., 2003, 45(1), 17-23.
74. Sigusch, B.W.; Pfitzner, A.; Albrecht, V.; Glockmann, E. Efficacy of photodynamic therapy on inflammatory signs and two selected periodontopathogenic species in a beagle dog model. J. Periodontol., 2005, 76(7), 1100-5.
75. Wakayama, Y.; Takagi, M.; Yano, K. Photosensitized inactivation of E. coli cells in toluidine blue-light system. Photochem. Photobiol., 1980, 32(5), 601-5.
76. Valduga, G.; Breda, B.; Giacometti, G.M.; Jori, G.; Reddi, E. Photosensitization of wild and mutant strains of Escherichia coli by meso-tetra (N-methyl-4-pyridyl)porphine. Biochem. Biophys. Res. Commun., 1999, 256(1), 84-8.