Two en-kaurene diterpenoids from Tibetan medicine Caryopteris toroetii

Zhongguo Zhongyao Zazhi

Volumn 34, Issue 12, 2009, Pages 1523-1526

  Que, Sheng ^a,b   Zhao, Yuying ^a   Zhou, Yong ^a   Zhang, Qingying ^a  

^a PEKING UNIVERSITY HEALTH SCIENCE CENTER   (China)

^b Department of Physics   (China)

Author keywords

Caryopteris; Caryopteris toroetii; En kaurene diterpenoid; Nodosin; Oridonin; Tibetan medicine

Indexed keywords

CARYOPTERIS TOROETII EXTRACT; DITERPENOID; NODOSIN; ORIDONIN; PLANT EXTRACT; UNCLASSIFIED DRUG;

ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; CHEMICAL STRUCTURE; CHROMATOGRAPHY; ELECTROSPRAY MASS SPECTROMETRY; EXTRACTION; PROTON NUCLEAR MAGNETIC RESONANCE; TIBETAN MEDICINE; TIME OF FLIGHT MASS SPECTROMETRY;

DITERPENES, KAURANE; DRUGS, CHINESE HERBAL; LAMIACEAE; MEDICINE, TIBETAN TRADITIONAL;

EID: 70349120887     PISSN: 10015302     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (24)

1. Ouang J, Wu L, Tashiro S, et al. Reactive oxygen species mediate oridonin-induced HepG2 apoptosis through p53, MAPK, and mitochondrial signaling pathways[J]. J Pharm Sci, 2008,107 (4):370.
2. Hu, A P, Du, J M, Li, J Y, et al. Oridonin promotes CD4 +/CD25 + Treg differentiation, modulates Th1/Th2 balance and induces HO-1 in rat splenic lymphocytes[J]. Inflamm Res, 2008, 57(7):340.
3. Hu, H Z, Yang Y B, Xu X D, et al. Oridonin induces apoptosis via P13K/Akt pathway in cervical carcinoma HeLa cell line[J]. Acta Pharm Sin, 2007,28(11):1819.
4. Zhou G B, Kang H, Wang L, et al. Oridonin, a diterpenoid extracted from medicinal herbs, targets AML1-ETO fusion protein and shows potent antitumor activity with low adverse effects on the leukemia in vitro and in vivo[J]. Blood, 2007,109(8):441. (Pubitemid 46572534)
5. Lu Y B, Sun C R, Pan Y J. Isolation and purification of pridonin from Rabdosia rubescens using upright counter-current chromatography[J]. J Sep Sci, 2006,29:314.
6. Meng X J, Wang Q G, Chen Y Z. Diterpenoids from Robdosia japonica[J]. Phytochemistry, 1989,28(4):1163.
7. Fujita E, Taoka M. Terpenoids XX the structure and absolute configuration of lasiokaurine and lasiodonin, new diterpenoids from Isodon lasiocarpus (Hayata) kudo[J]. Chem Pharm Bull, 1972,20(8):1752.
8. Fujita E, Fujita T, Katayama H, et al. Terpenoids XV. Structure and absolute configuration of oridonin isolated from Isodon japonicus and Isodon tricocarpus[J]. J Chem Soc (C), 1970: 1674.
9. Fujita E, Fujita T, Katayama H, et al. Oridonin, a new diterpenoid from Isodon species[J]. Chem Commun, 1967:252.
10. Osawa K, Yasuda H, Maruyama T, et al. An investigation of diterpenes from the leaves of Robdosia trichocarpa and their antibacterial activity against microorganisms[J]. Chem Pharm Bull, 1994,420(4):922.
11. Liu H M, Yan X B, Kiuchi F, et al. A new diterpene glycoside from Robdosia albescens[J]. Chem Pharm Bull, 2000,48(1): 148. (Pubitemid 30074957)
12. [21 ] Wang X R, Hu H P, Wang H P, et al. Nervosanin A and B and ent-kauranoids from Isodon nervosus[J]. Phytochemistry, 1994, 37(5):1367.
13. Takada Y, Matsumoto T, Longirabdolide C. a new diterpenoid from Robdosia longituba[J]. J Nat Prod, 1994,57(5):650. (Pubitemid 24196762)
14. Fujita E, Fujita T, Taoka M. Terpenoids. VII. The structure and absolute configuration of nodosin, a new diterpenoid from Isodon species[J]. Chem Pharm Bull, 1968,16(3):509.