Conjunctival mucin MRNA expression in contact lens wear

Optometry and Vision Science

Volumn 86, Issue 9, 2009, Pages 1051-1058

  Corrales, Rosa M ^a,b   Galarreta, David ^b   Herreras, Jose M ^a   Saez, Victoria ^a   Arranz, Isabel ^b   González, Maria J ^a,b   Mayo, Agustin ^b   Calonge, Margarita ^a,b   Chaves, Felipe J ^c  

^a BIOMATERIALES Y NANOMEDICINA CIBER BBN   (Spain)

^b UNIVERSITY OF VALLADOLID   (Spain)

^c HOSPITAL CLÍNICO UNIVERSITARIO   (Spain)

Author keywords

Contact lens; Impression cytology; Mucin gene expression; Real time PCR; Water content

Indexed keywords

BASAL LEVELS; BULBAR CONJUNCTIVA; CONTACT LENS WEAR; HEALTHY SUBJECTS; HIGH WATER CONTENT; IMPRESSION CYTOLOGY; LOW WATER-CONTENT; MRNA EXPRESSION; MRNA LEVEL; MUCIN GENE EXPRESSION; NONIONIC; POLYMERASE CHAIN REACTION; QUANTITATIVE REAL TIME PCR; REAL TIME PCR; STATISTICALLY SIGNIFICANT DIFFERENCE;

BIOACTIVITY; CELLS; CONTACT LENSES; CYTOLOGY; GENE EXPRESSION; IONIZATION OF LIQUIDS; NUCLEIC ACIDS; OPTICAL INSTRUMENTS; RNA;

WATER CONTENT;

GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; MESSENGER RNA; MUCIN; MUCIN 1; MUCIN 15; MUCIN 16; MUCIN 17; MUCIN 2; MUCIN 4; MUCIN 5AC; MUCIN 7; OLIGONUCLEOTIDE; UNCLASSIFIED DRUG;

ADULT; ARTICLE; CONJUNCTIVA; CONTACT LENS; CONTROLLED STUDY; FEMALE; GENE AMPLIFICATION; GENE EXPRESSION; GENE ISOLATION; GENE SEQUENCE; HUMAN; HUMAN EXPERIMENT; HYDROGEL; IMPRESSION CYTOLOGY; MALE; NORMAL HUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION; WATER CONTENT;

ADOLESCENT; ADULT; CONJUNCTIVA; CONTACT LENSES, HYDROPHILIC; DOWN-REGULATION; EQUIPMENT DESIGN; GENE EXPRESSION; HUMANS; HYDROGEL; MUCINS; RNA, MESSENGER; TIME FACTORS; UP-REGULATION; YOUNG ADULT;

EID: 70349104228     PISSN: 10405488     EISSN: None     Source Type: Journal    
DOI: 10.1097/OPX.0b013e3181b4f02e     Document Type: Article

References (46)

1. Farris RL. The dry eye: its mechanisms and therapy, with evidence that contact lens is a cause. CLAO J 1986;12:234-246
2. Lemp MA. Report of the National Eye Institute/Industry workshop on Clinical Trials in Dry Eyes. CLAO J 1995;21:221-232
3. Dart JK, Stapleton F, Minassian D. Contact lenses and other risk factors in microbial keratitis. Lancet 1991;338:650-653
4. Korb DR. Tear film-contact lens interactions. Adv Exp Med Biol 1994;350:403-410
5. Inatomi T, Spurr-Michaud S, Tisdale AS, Gipson IK. Human corneal and conjunctival epithelia express MUC1 mucin. Invest Ophthalmol Vis Sci 1995;36:1818-1827
6. Inatomi T, Spurr-Michaud S, Tisdale AS, Zhan Q, Feldman ST, Gipson IK. Expression of secretory mucin genes by human conjunctival epithelia. Invest Ophthalmol Vis Sci 1996;37:1684-1692
7. Berry M, Ellingham RB, Corfield AP. Polydispersity of normal human conjunctival mucins. Invest Ophthalmol Vis Sci 1996;37: 2559-2571
8. Jumblatt MM, McKenzie RW, Jumblatt JE. MUC5AC mucin is a component of the human precorneal tear film. Invest Ophthalmol Vis Sci 1999;40:43-49
9. Pflugfelder SC, Liu Z, Monroy D, Li DQ, Carvajal ME, Price-Schiavi SA, Idris N, Solomon A, Perez A, Carraway KL. Detection of sialomucin complex (MUC4) in human ocular surface epithelium and tear fluid. Invest Ophthalmol Vis Sci 2000;41:1316-1326
10. McKenzie RW, Jumblatt JE, Jumblatt MM. Quantification of MUC2 and MUC5AC transcripts in human conjunctiva. Invest Ophthalmol Vis Sci 2000;41:703-708
11. Diebold Y, Corrales RM, Calonge M, Saez MV, Callejo S, Lazaro MC, Herreras JM. Human conjunctival epithelium in culture: a tool to assay new therapeutic strategies for dry eye. Adv Exp Med Biol 2002;506:307-311
12. Jumblatt MM, McKenzie RW, Steele PS, Emberts CG, Jumblatt JE. MUC7 expression in the human lacrimal gland and conjunctiva. Cornea 2003;22:41-45
13. Corrales RM, Calonge M, Herreras JM, Saez V, Chaves FJ. Human epithelium from conjunctival impression cytology expresses MUC7 mucin gene. Cornea 2003;22:665-671 (Pubitemid 37175147)
14. Corrales RM, Calonge M, Herreras JM, Saez V, Mayo A, Chaves FJ. Levels of mucin gene expression in normal human conjunctival epithelium in vivo. Curr Eye Res 2003;27:323-328 (Pubitemid 37445270)
15. Corrales RM, Galarreta DJ, Herreras JM, Calonge M, Chaves FJ. [Normal human conjunctival epithelium expresses MUC13, MUC15, MUC16 and MUC17 mucin genes.] Arch Soc Esp Oftalmol 2003;78:375-381
16. Knop E, Brewitt H. Induction of conjunctival epithelial alterations by contact lens wearing. A prospective study. Ger J Ophthalmol 1992;1:125-134
17. Knop E, Brewitt H. Conjunctival cytology in asymptomatic wearers of soft contact lenses. Graefes Arch Clin Exp Ophthalmol 1992;230: 340-347
18. Anshu, Munshi MM, Sathe V, Ganar A. Conjunctival impression cytology in contact lens wearers. Cytopathology 2001;12:314-320
19. Adar S, Kanpolat A, Surucu S, Ucakhan OO. Conjunctival impression cytology in patients wearing contact lenses. Cornea 1997;16: 289-294
20. Pisella PJ, Malet F, Lejeune S, Brignole F, Debbasch C, Bara J, Rat P, Colin J, Baudouin C. Ocular surface changes induced by contact lens wear. Cornea 2001;20:820-825
21. Calonge M, Diebold Y, Saez V, Enriquez de Salamanca A, Garcia-Vazquez C, Corrales RM, Herreras JM. Impression cytology of the ocular surface: a review. Exp Eye Res 2004;78:457-472
22. Lemp MA. Contact lenses and associated anterior segment disorders: dry eye, blepharitis, and allergy. Ophthalmol Clin North Am 2003; 16:463-469
23. Broad Institute. Software Archive: Primer3. Available at: http:// www-genome.wi.mit.edu/genome-software/other/primer3.html. Accessed June 24, 2009.
24. Debailleul V, Laine A, Huet G, Mathon P, d'Hooghe MC, Aubert JP, Porchet N. Human mucin genes MUC2, MUC3, MUC4, MUC5AC, MUC5B, and MUC6 express stable and extremely large mRNAs and exhibit a variable length polymorphism. An improved method to analyze large mRNAs. J Biol Chem 1998;273:881-890
25. Gum JR, Byrd JC, Hicks JW, Toribara NW, Lamport DT, Kim YS. Molecular cloning of human intestinal mucin cDNAs. Sequence analysis and evidence for genetic polymorphism. J Biol Chem 1989; 264:6480-6487
26. Gum JR, Hicks JW, Swallow DM, Lagace RL, Byrd JC, Lamport DT, Siddiki B, Kim YS. Molecular cloning of cDNAs derived from a novel human intestinal mucin gene. Biochem Biophys Res Commun 1990;171:407-415
27. Moniaux N, Nollet S, Porchet N, Degand P, Laine A, Aubert JP. Complete sequence of the human mucin MUC4: a putative cell membrane-associated mucin. Biochem J 1999;338(Pt 2):325-333
28. Mehrotra R, Thornton DJ, Sheehan JK. Isolation and physical characterization of the MUC7 (MG2) mucin from saliva: evidence for self-association. Biochem J 1998;334(Pt 2):415-422
29. Meezaman D, Charles P, Daskal E, Polymeropoulos MH, Martin BM, Rose MC. Cloning and analysis of cDNA encoding a major airway glycoprotein, human tracheobronchial mucin (MUC5). J Biol Chem 1994;269:12932-12939
30. Lapensee L, Paquette Y, Bleau G. Allelic polymorphism and chromosomal localization of the human oviductin gene (MUC9). Fertil Steril 1997;68:702-708
31. Williams SJ, McGuckin MA, Gotley DC, Eyre HJ, Sutherland GR, Antalis TM. Two novel mucin genes down-regulated in colorectal cancer identified by differential display. Cancer Res 1999;59: 4083-4089
32. Williams SJ, Wreschner DH, Tran M, Eyre HJ, Sutherland GR, McGuckin MA. MUC13, a novel human cell surface mucin expressed by epithelial and hemopoietic cells. J Biol Chem 2001;276: 18327-18336
33. Pallesen LT, Berglund L, Rasmussen LK, Petersen TE, Rasmussen JT. Isolation and characterization of MUC15, a novel cell membraneassociated mucin. Eur J Biochem 2002;269:2755-2763
34. Yin BW, Lloyd KO. Molecular cloning of the CA125 ovarian cancer antigen: identification as a new mucin, MUC16. J Biol Chem 2001; 276:27371-27375
35. Gum JR Jr, Crawley SC, Hicks JW, Szymkowski DE, Kim YS. MUC17, a novel membrane-tethered mucin. Biochem Biophys Res Commun 2002;291:466-475
36. Chen Y, Zhao YH, Kalaslavadi TB, Hamati E, Nehrke K, Le AD, Ann DK, Wu R. Genome-wide search and identification of a novel gel-forming mucin MUC19/Muc19 in glandular tissues. Am J Respir Cell Mol Biol 2004;30:155-165
37. Higuchi T, Orita T, Nakanishi S, Katsuya K, Watanabe H, Yamasaki Y, Waga I, Nanayama T, Yamamoto Y, Munger W, Sun HW, Falk RJ, Jennette JC, Alcorta DA, Li H, Yamamoto T, Saito Y, Nakamura M. Molecular cloning, genomic structure, and expression analysis of MUC20, a novel mucin protein, up-regulated in injured kidney. J Biol Chem 2004;279:1968-1979
38. Yu DF, Chen Y, Han JM, Zhang H, Chen XP, Zou WJ, Liang LY, Xu CC, Liu ZG. MUC19 expression in human ocular surface and lacrimal gland and its alteration in Sjogren syndrome patients. Exp Eye Res 2008;86:403-411
39. Corrales RM, Calonge M, Saez V, Mayo A, Herreras JM, Chaves FJ. Range of mucin gene expression in normal human conjunctival epithelium in vivo. Invest Ophthalmol Vis Sci 2002;43:E-Abstract 2464.
40. Calonge MC, Corrales RM, Saez V, Mayo A, Herreras JM, Stern ME, Chaves FJ. Alteration of conjunctival mucin gene expression in teardeficient dry eye syndrome. Invest Ophthalmol Vis Sci 2003;44: E-Abstract 2508.
41. Calonge MC, Corrales RM, Saez V, García-Vázquez C, Mayo A, Chaves FJ, Stern ME, Herreras JM. Can ocular mucin gene levels be used as an investigational diagnostic test for dry eye? Invest Ophthalmol Vis Sci 2005;46:E-Abstract 4465.
42. Gururaja TL, Levine JH, Tran DT, Naganagowda GA, Ramalingam K, Ramasubbu N, Levine MJ. Candidacidal activity prompted by N-terminus histatin-like domain of human salivary mucin (MUC7)1. Biochim Biophys Acta 1999;1431:107-119
43. Baughan LW, Robertello FJ, Sarrett DC, Denny PA, Denny PC. Salivary mucin as related to oral Streptococcus mutans in elderly people. Oral Microbiol Immunol 2000;15:10-14
44. Situ H, Wei G, Smith CJ, Mashhoon S, Bobek LA. Human salivary MUC7 mucin peptides: effect of size, charge and cysteine residues on antifungal activity. Biochem J 2003;375:175-182.
45. Berry M, Harris A, Lumb R, Powell K. Commensal ocular bacteria degrade mucins. Br J Ophthalmol 2002;86:1412-1416
46. Dejaco-Ruhswurm I, Scholz U, Hanselmayer G, Skorpik C. Contact lens induced keratitis associated with contact lens wear. Acta Ophthalmol Scand 2001;79:479-483