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Volumn 21, Issue 12, 2006, Pages 1946-1954

RANKL inhibition: A novel strategy to decrease femoral head deformity after ischemic osteonecrosis

Author keywords

Femoral head deformity; Legg Calve Perthes disease; Osteonecrosis; Osteoprotegerin; RANKL

Indexed keywords

HUMAN OSTEOPROTEGERIN FRAGMENT CRYSTALLIZABLE; OSTEOCLAST DIFFERENTIATION FACTOR; OSTEOPROTEGERIN; SODIUM CHLORIDE; UNCLASSIFIED DRUG;

EID: 33845206554     PISSN: 08840431     EISSN: None     Source Type: Journal    
DOI: 10.1359/jbmr.060905     Document Type: Article
Times cited : (69)

References (50)
  • 1
    • 0023014508 scopus 로고
    • Osteoarthritis of the young adult hip: Etiology and treatment
    • Anderson L (ed.) American Academy of Orthopaedic Surgeons, Park Ridge, IL, USA
    • Aronson J 1986 Osteoarthritis of the young adult hip: Etiology and treatment. In: Anderson L (ed.) Instructional Course Lectures, vol. 35. American Academy of Orthopaedic Surgeons, Park Ridge, IL, USA, pp. 119-128.
    • (1986) Instructional Course Lectures , vol.35 , pp. 119-128
    • Aronson, J.1
  • 2
    • 0021265430 scopus 로고
    • A long-tern follow-up of Legg-Calve-Perthes disease
    • Mc Andrew M, Weinstein SL 1984 A long-tern follow-up of Legg-Calve-Perthes disease. J Bone Joint Surg Am 66:860-869.
    • (1984) J Bone Joint Surg Am , vol.66 , pp. 860-869
    • Mc Andrew, M.1    Weinstein, S.L.2
  • 4
    • 33644495145 scopus 로고
    • Coxa plana. A histo-pathologic and arthographic study
    • Jonsater S 1953 Coxa plana. A histo-pathologic and arthographic study. Acta Orthop Scand Suppl 12:25-54.
    • (1953) Acta Orthop Scand Suppl , vol.12 , pp. 25-54
    • Jonsater, S.1
  • 5
    • 0017102696 scopus 로고
    • Legg-Calve-Perthes' disease - Morphological studies in two cases examined at necropsy
    • Jensen OM, Lauritzen J 1976 Legg-Calve-Perthes' disease - morphological studies in two cases examined at necropsy. J Bone Joint Surg Br 58:332-338.
    • (1976) J Bone Joint Surg Br , vol.58 , pp. 332-338
    • Jensen, O.M.1    Lauritzen, J.2
  • 6
    • 0016172437 scopus 로고
    • Pathological changes in a case of Perthes' disease
    • McKibbin B, Ralis Z, Wales C 1974 Pathological changes in a case of Perthes' disease. J Bone Joint Surg Br 56:438-447.
    • (1974) J Bone Joint Surg Br , vol.56 , pp. 438-447
    • McKibbin, B.1    Ralis, Z.2    Wales, C.3
  • 7
    • 0000401706 scopus 로고    scopus 로고
    • Legg-Calve-Perthes syndrome
    • Morrisy RT, Weinstein SL (eds.) Lippincott-Raven, Philadelphia, PA, USA
    • Weinstein SL 1996 Legg-Calve-Perthes syndrome. In: Morrisy RT, Weinstein SL (eds.) Lovell and Winter's Pediatric Orthopaedics, 4th ed., vol. II. Lippincott-Raven, Philadelphia, PA, USA, pp. 951-991.
    • (1996) Lovell and Winter's Pediatric Orthopaedics, 4th Ed. , vol.2 , pp. 951-991
    • Weinstein, S.L.1
  • 8
    • 0036704158 scopus 로고    scopus 로고
    • Development of flattening and apparent fragmentation following ischemic necrosis of the capital femoral epiphysis in a piglet model
    • Kim HK, Su PH 2002 Development of flattening and apparent fragmentation following ischemic necrosis of the capital femoral epiphysis in a piglet model. J Bone Joint Surg Am 84:1329-1334.
    • (2002) J Bone Joint Surg Am , vol.84 , pp. 1329-1334
    • Kim, H.K.1    Su, P.H.2
  • 9
    • 34248400391 scopus 로고    scopus 로고
    • Systemic alendronate prevents resorption of necrotic bone during revascularization. A bone chamber study in rats
    • Astrand J, Aspenberg P 2002 Systemic alendronate prevents resorption of necrotic bone during revascularization. A bone chamber study in rats. BMC Musculoskelet Disord 3:19-23.
    • (2002) BMC Musculoskelet Disord , vol.3 , pp. 19-23
    • Astrand, J.1    Aspenberg, P.2
  • 10
    • 14644394975 scopus 로고    scopus 로고
    • Ibandronate for prevention of femoral head deformity after ischemic necrosis of the capital femoral epiphysis in immature pigs
    • Kim HK, Randall TS, Bian H, Jenkins J, Garces A, Bauss F 2005 Ibandronate for prevention of femoral head deformity after ischemic necrosis of the capital femoral epiphysis in immature pigs. J Bone Joint Surg Am 87:550-557.
    • (2005) J Bone Joint Surg Am , vol.87 , pp. 550-557
    • Kim, H.K.1    Randall, T.S.2    Bian, H.3    Jenkins, J.4    Garces, A.5    Bauss, F.6
  • 11
    • 0242412963 scopus 로고    scopus 로고
    • Zoledronic acid treatment results in retention of femoral head structure after traumatic osteonecrosis in young Wistar rats
    • Little DG, Peat RA, McEvoy A, Williams PR, Smith EJ, Baldock PA 2003 Zoledronic acid treatment results in retention of femoral head structure after traumatic osteonecrosis in young Wistar rats. J Bone Miner Res 18:2016-2022.
    • (2003) J Bone Miner Res , vol.18 , pp. 2016-2022
    • Little, D.G.1    Peat, R.A.2    McEvoy, A.3    Williams, P.R.4    Smith, E.J.5    Baldock, P.A.6
  • 13
    • 14944357304 scopus 로고    scopus 로고
    • Efficacy of alendronate, a bisphosphonate, in the treatment of AVN of the hip. A prospective open-label study
    • Agarwala S, Jain D, Joshi VR, Sule A 2005 Efficacy of alendronate, a bisphosphonate, in the treatment of AVN of the hip. A prospective open-label study. Rheumatol 44:352-359.
    • (2005) Rheumatol , vol.44 , pp. 352-359
    • Agarwala, S.1    Jain, D.2    Joshi, V.R.3    Sule, A.4
  • 14
    • 26044465056 scopus 로고    scopus 로고
    • The use of alendronate to prevent early collapse of the femoral head in patients with nontraumatic osteonecrosis. A randomized clinical study
    • Lai KA, Shen WJ, Yang CY, Shao CJ, Hsu JT, Lin RM 2005 The use of alendronate to prevent early collapse of the femoral head in patients with nontraumatic osteonecrosis. A randomized clinical study. J Bone Joint Surg Am 87:2155-2159.
    • (2005) J Bone Joint Surg Am , vol.87 , pp. 2155-2159
    • Lai, K.A.1    Shen, W.J.2    Yang, C.Y.3    Shao, C.J.4    Hsu, J.T.5    Lin, R.M.6
  • 15
    • 0037673945 scopus 로고    scopus 로고
    • Osteoclast differentiation and activation
    • Boyle WJ, Simonet WS, Lacey DL 2003 Osteoclast differentiation and activation. Nature 423:337-342.
    • (2003) Nature , vol.423 , pp. 337-342
    • Boyle, W.J.1    Simonet, W.S.2    Lacey, D.L.3
  • 16
    • 9244252016 scopus 로고    scopus 로고
    • The molecular triad OPG/RANK/RANKL: Involvement in the orchestration of pathophysiological bone remodeling
    • Theoleyre S, Wittrant Y, Tat SK, Fortun Y, Redini F, Heymann D 2004 The molecular triad OPG/RANK/RANKL: Involvement in the orchestration of pathophysiological bone remodeling. Cytokine Growth Factor Rev 15:457-475.
    • (2004) Cytokine Growth Factor Rev , vol.15 , pp. 457-475
    • Theoleyre, S.1    Wittrant, Y.2    Tat, S.K.3    Fortun, Y.4    Redini, F.5    Heymann, D.6
  • 17
    • 0035024957 scopus 로고    scopus 로고
    • Osteoprotegerin: A physiological and pharmacological inhibitor of bone resorption
    • Kostenuik PJ, Shalhoub V 2001 Osteoprotegerin: A physiological and pharmacological inhibitor of bone resorption. Curr Pharm Des 7:613-635.
    • (2001) Curr Pharm des , vol.7 , pp. 613-635
    • Kostenuik, P.J.1    Shalhoub, V.2
  • 21
    • 17144461830 scopus 로고    scopus 로고
    • Histopathologic changes in growth plate cartilage following ischemic necrosis of the capital femoral epiphysis
    • Kim HKW, Su P-H, Qiu Y-S 2001 Histopathologic changes in growth plate cartilage following ischemic necrosis of the capital femoral epiphysis. J Bone Joint Surg Am 83:688-697.
    • (2001) J Bone Joint Surg Am , vol.83 , pp. 688-697
    • Kim, H.K.W.1    Su, P.-H.2    Qiu, Y.-S.3
  • 23
    • 0347029832 scopus 로고    scopus 로고
    • Indentation properties of growing femoral head following ischemic necrosis
    • Pringle D, Koob TJ, Kim HK 2004 Indentation properties of growing femoral head following ischemic necrosis. J Orthop Res 22:122-130.
    • (2004) J Orthop Res , vol.22 , pp. 122-130
    • Pringle, D.1    Koob, T.J.2    Kim, H.K.3
  • 24
    • 76549230919 scopus 로고
    • Legg-Perthes disease: A method for the measurement of the roentgenographic result
    • Heyman CH, Herndon CH 1950 Legg-Perthes disease: A method for the measurement of the roentgenographic result. J Bone Joint Surg Am 32:767-778.
    • (1950) J Bone Joint Surg Am , vol.32 , pp. 767-778
    • Heyman, C.H.1    Herndon, C.H.2
  • 25
    • 0035747758 scopus 로고    scopus 로고
    • Comparison of blood markers for the longitudinal monitoring of osteoclastic activity in the pig
    • Weile U, Finsler S, Wehr U, Claus R 2001 Comparison of blood markers for the longitudinal monitoring of osteoclastic activity in the pig. J Vet Med A Physiol Pathol Clin Med 48:609-618.
    • (2001) J Vet Med A Physiol Pathol Clin Med , vol.48 , pp. 609-618
    • Weile, U.1    Finsler, S.2    Wehr, U.3    Claus, R.4
  • 28
    • 0036155498 scopus 로고    scopus 로고
    • In vivo RANK signaling blockade using the receptor activator of NF-kappaB:Fc effectively prevents and ameliorates wear debris-induced osteolysis via osteoclast depletion without inhibiting osteogenesis
    • Childs LM, Paschalis EP, Xing L, Dougall WC, Anderson D, Boskey AL, Puzas JE, Rosier RN, O'Keefe RJ, Boyce BF, Schwarz EM 2002 In vivo RANK signaling blockade using the receptor activator of NF-kappaB:Fc effectively prevents and ameliorates wear debris-induced osteolysis via osteoclast depletion without inhibiting osteogenesis. J Bone Miner Res 17:192-199.
    • (2002) J Bone Miner Res , vol.17 , pp. 192-199
    • Childs, L.M.1    Paschalis, E.P.2    Xing, L.3    Dougall, W.C.4    Anderson, D.5    Boskey, A.L.6    Puzas, J.E.7    Rosier, R.N.8    O'Keefe, R.J.9    Boyce, B.F.10    Schwarz, E.M.11
  • 31
    • 0035866796 scopus 로고    scopus 로고
    • Therapeutic efficacy of a soluble receptor activator of nuclear factor kappaB-IgG Fc fusion protein in suppressing bone resorption and hypercalcemia in a model of humoral hypercalcemia of malignancy
    • Oyajobi BO, Anderson DM, Traianedes K, Williams PJ, Yoneda T, Mundy GR 2001 Therapeutic efficacy of a soluble receptor activator of nuclear factor kappaB-IgG Fc fusion protein in suppressing bone resorption and hypercalcemia in a model of humoral hypercalcemia of malignancy. Cancer Res 61:2572-2578.
    • (2001) Cancer Res , vol.61 , pp. 2572-2578
    • Oyajobi, B.O.1    Anderson, D.M.2    Traianedes, K.3    Williams, P.J.4    Yoneda, T.5    Mundy, G.R.6
  • 32
    • 12144289393 scopus 로고    scopus 로고
    • Repair of local bone erosions and reversal of systemic bone loss upon therapy with anti-tumor necrosis factor in combination with osteoprotegerin or parathyroid hormone in tumor necrosis factor-mediated arthritis
    • Redlich K, Gortz B, Hayer S, Zwerina J, Doerr N, Kostenuik P, Bergmeister H, Kollias G, Steiner G, Smolen JS, Schett G 2004 Repair of local bone erosions and reversal of systemic bone loss upon therapy with anti-tumor necrosis factor in combination with osteoprotegerin or parathyroid hormone in tumor necrosis factor-mediated arthritis. Am J Pathol 164:543-555.
    • (2004) Am J Pathol , vol.164 , pp. 543-555
    • Redlich, K.1    Gortz, B.2    Hayer, S.3    Zwerina, J.4    Doerr, N.5    Kostenuik, P.6    Bergmeister, H.7    Kollias, G.8    Steiner, G.9    Smolen, J.S.10    Schett, G.11
  • 33
    • 0018930378 scopus 로고
    • Methods of measuring in Legg-Calve-Perthes Disease with special regard to the prognosis
    • Mose K 1980 Methods of measuring in Legg-Calve-Perthes Disease with special regard to the prognosis. Clin Orthop 150:103-109.
    • (1980) Clin Orthop , vol.150 , pp. 103-109
    • Mose, K.1
  • 35
    • 2442763187 scopus 로고    scopus 로고
    • Long-term prognosis of Legg-Calve-Perthes disease: A meta-analysis
    • Yrjonen T 1999 Long-term prognosis of Legg-Calve-Perthes disease: A meta-analysis. J Pediatr Orthop B 8:169-172.
    • (1999) J Pediatr Orthop B , vol.8 , pp. 169-172
    • Yrjonen, T.1
  • 36
    • 0035360265 scopus 로고    scopus 로고
    • Osteoprotegerin inhibits osteolysis and decreases skeletal tumor burden in syngeneic and nude mouse models of experimenlal bone metastasis
    • Morony S, Capparelli C, Sarosi I, Lacey DL, Dunstan CR, Kostenuik PJ 2001 Osteoprotegerin inhibits osteolysis and decreases skeletal tumor burden in syngeneic and nude mouse models of experimenlal bone metastasis. Cancer Res 61:4432-4436.
    • (2001) Cancer Res , vol.61 , pp. 4432-4436
    • Morony, S.1    Capparelli, C.2    Sarosi, I.3    Lacey, D.L.4    Dunstan, C.R.5    Kostenuik, P.J.6
  • 39
    • 0033573882 scopus 로고    scopus 로고
    • Nitrogen-containing bisphosphonates inhibit isopentenyl pyrophosphate isomerase/farnesyl pyrophosphate synthase activity with relative potencies corresponding to their antiresorptive potencies in vitro and in vivo
    • van Beek E, Pieterman E, Cohen L, Lowik C, Papapoulos S 1999 Nitrogen-containing bisphosphonates inhibit isopentenyl pyrophosphate isomerase/farnesyl pyrophosphate synthase activity with relative potencies corresponding to their antiresorptive potencies in vitro and in vivo. Biochem Biophys Res Commun 255:491-494.
    • (1999) Biochem Biophys Res Commun , vol.255 , pp. 491-494
    • Van Beek, E.1    Pieterman, E.2    Cohen, L.3    Lowik, C.4    Papapoulos, S.5
  • 41
    • 20544468667 scopus 로고    scopus 로고
    • Combined treatment with PTH (1-34) and OPG increases bone volume and uniformity of mineralization in aged ovariectomized rats
    • Valenta A, Roschger P, Fratzl-Zelman N, Kostenuik PJ, Dunstan CR, Fratzl P, Klaushofer K 2005 Combined treatment with PTH (1-34) and OPG increases bone volume and uniformity of mineralization in aged ovariectomized rats. Bone 37:87-95.
    • (2005) Bone , vol.37 , pp. 87-95
    • Valenta, A.1    Roschger, P.2    Fratzl-Zelman, N.3    Kostenuik, P.J.4    Dunstan, C.R.5    Fratzl, P.6    Klaushofer, K.7
  • 42
    • 20844434038 scopus 로고    scopus 로고
    • Additive bone-protective effects of anabolic treatment when used in conjunction with RANKL and tumor necrosis factor inhibition in two rat arthritis models
    • Schett G, Middleton S, Bolon B, Stolina M, Brown H, Zhu L, Pretorius J, Zack DJ, Kostenuik P, Feige U 2005 Additive bone-protective effects of anabolic treatment when used in conjunction with RANKL and tumor necrosis factor inhibition in two rat arthritis models. Arthritis Rheum 52:1604-1611.
    • (2005) Arthritis Rheum , vol.52 , pp. 1604-1611
    • Schett, G.1    Middleton, S.2    Bolon, B.3    Stolina, M.4    Brown, H.5    Zhu, L.6    Pretorius, J.7    Zack, D.J.8    Kostenuik, P.9    Feige, U.10
  • 43
    • 0032468984 scopus 로고    scopus 로고
    • Bisphosphonates: Mechanisms of action
    • Fleisch H 1998 Bisphosphonates: Mechanisms of action. Endocr Rev 19:80-100.
    • (1998) Endocr Rev , vol.19 , pp. 80-100
    • Fleisch, H.1
  • 44
    • 33744804800 scopus 로고    scopus 로고
    • Local bioavailability and distribution of systemically (parenterally) administered ibandronate in the infarcted femoral head
    • Kim HK, Sanders M, Athavale S, Bian H, Bauss F 2006 Local bioavailability and distribution of systemically (parenterally) administered ibandronate in the infarcted femoral head. Bone 39:205-212.
    • (2006) Bone , vol.39 , pp. 205-212
    • Kim, H.K.1    Sanders, M.2    Athavale, S.3    Bian, H.4    Bauss, F.5
  • 45
    • 0029886359 scopus 로고    scopus 로고
    • Bisphosphonates: A review of their pharmacokinetic properties
    • Lin JH 1996 Bisphosphonates: A review of their pharmacokinetic properties. Bone 18:75-85.
    • (1996) Bone , vol.18 , pp. 75-85
    • Lin, J.H.1
  • 46
    • 0031800988 scopus 로고    scopus 로고
    • Mechanisms of action of bisphosphonates
    • Rodan GA 1998 Mechanisms of action of bisphosphonates. Annu Rev Pharmacol Toxicol 38:375-388.
    • (1998) Annu Rev Pharmacol Toxicol , vol.38 , pp. 375-388
    • Rodan, G.A.1
  • 48
    • 0035102073 scopus 로고    scopus 로고
    • Long-term effect of incadronate disodium (YM-175) on fracture healing of femoral shaft in growing rats
    • Li C, Mori S, Li J, Kaji Y, Akiyama T, Kawanishi J, Norimatsu H 2001 Long-term effect of incadronate disodium (YM-175) on fracture healing of femoral shaft in growing rats. J Bone Miner Res 16:429-436.
    • (2001) J Bone Miner Res , vol.16 , pp. 429-436
    • Li, C.1    Mori, S.2    Li, J.3    Kaji, Y.4    Akiyama, T.5    Kawanishi, J.6    Norimatsu, H.7


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