Identification of genes expressed preferentially in the developing peripheral margin of the optic cup

Developmental Dynamics

Volumn 238, Issue 9, 2009, Pages 2327-2329

  Trimarchi, Jeffrey M ^a   Cho, Seo Hee ^a,b   Cepko, Constance L ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

^b UNIVERSITY OF TEXAS MEDICAL SCHOOL   (United States)

Author keywords

Canonical Wnt signaling; Ciliary body; Iris; Peripheral optic cup; Single cell profiling

Indexed keywords

BETA CATENIN; BONE MORPHOGENETIC PROTEIN 4; CD38 ANTIGEN; CD63 ANTIGEN; CELL ADHESION MOLECULE; CLUSTERIN; CYCLIN D2; CYCLIN D3; FIBROBLAST GROWTH FACTOR; FIBROBLAST GROWTH FACTOR RECEPTOR 2; LYMPHOID ENHANCER FACTOR 1; MESSENGER RNA; NOTCH2 RECEPTOR; OSTEOGENIC PROTEIN 1; PROTEIN P57; SOMATOMEDIN B; SOMATOMEDIN BINDING PROTEIN 5; TRANSCOBALAMIN II; TRANSCRIPTION FACTOR FOXP2; TRANSFORMING GROWTH FACTOR BETA2; VINCULIN; WNT PROTEIN;

ALDH 1 A1 GENE; ALDH 1 A3 GENE; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BMP 4 GENE; BMP 7 GENE; CD 38 GENE; CD 63 GENE; CELL ISOLATION; CHICKEN; CILIARY BODY; CLUSTERIN GENE; COLLAGEN IX GENE; CRHBP GENE; CYCLIN D2 GENE; CYCLIN D3 GENE; CYCLIN E1 GENE; DEVELOPMENTAL STAGE; DHRS 8 GENE; EMBRYO; EYE DEVELOPMENT; FGF 15 GENE; FGFR 2 GENE; FOXP 2 GENE; FRIZZLED 4 GENE; GAS 1 GENE; GENE EXPRESSION; GENE IDENTIFICATION; GENE INDUCTION; H 19 GENE; IGF 2 GENE; IGFBP 5 GENE; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; IRIS; IRS 4 GENE; LEF 1 GENE; LTBP 1 GENE; MARKER GENE; MICROARRAY ANALYSIS; MOUSE; NEWBORN; NINJURIN 1 GENE; NONHUMAN; NOTCH 2 GENE; NPNT GENE; NUCLEOTIDE SEQUENCE; ONCOGENE MYC; OPTIC DISK CUP; OTX 1 GENE; P 57 GENE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; REST GENE; RETINA; RHOMBOID FAMILY 1 GENE; SGK GENE; SIGNAL TRANSDUCTION; SOX 2 GENE; TCF 3 GENE; TGFB 2 GENE; TRANSCOBALAMIN 2 GENE; VINCULIN GENE; WFDC 1 GENE; ZIC 1 GENE; ZIC 2 GENE;

EID: 70349094956     PISSN: 10588388     EISSN: 10970177     Source Type: Journal    
DOI: 10.1002/dvdy.21973     Document Type: Article

References (58)

1. Acampora D, Mazan S, Avantaggiato V, Barone P, Tuorto F, Lallemand Y, Brulet P, Simeone A. 1996. Epilepsy and brain abnormalities in mice lacking the Otx1 gene. Nat Genet 14:218-222. (Pubitemid 26338809)
2. Ahmad I, Dooley CM, Thoreson WB, Rogers JA, Afiat S. 1999. In vitro analysis of a mammalian retinal progenitor that gives rise to neurons and glia. Brain Res 831:1-10.
3. Araki T, Milbrandt J. 1996. Ninjurin, a novel adhesion molecule, is induced by nerve injury and promotes axonal growth. Neuron 17:353-361. (Pubitemid 26296161)
4. Beebe DC. 1986. Development of the ciliary body: a brief review. Trans Ophthalmol Soc U K 105:123-130.
5. Blackshaw S, Harpavat S, Trimarchi J, Cai L, Huang H, Kuo WP, Weber G, Lee K, Fraioli RE, Cho SH, Yung R, Asch E, Ohno-Machado L, Wong WH, Cepko CL. 2004. Genomic analysis of mouse retinal development. PLoS Biol 2:E247. (Pubitemid 39245250)
6. Brady G, Iscove NN. 1993. Construction of cDNA libraries from single cells. Methods Enzymol 225:611-623. (Pubitemid 23301548)
7. Brandenberger R, Schmidt A, Linton J, Wang D, Backus C, Denda S, Muller U, Reichardt LF. 2001. Identification and characterization of a novel extracellular matrix protein nephronectin that is associated with integrin alpha8beta1 in the embryonic kidney. J Cell Biol 154:447-458. (Pubitemid 34286153)
8. Capdevila J, Tabin C, Johnson RL. 1998. Control of dorsoventral somite patterning by Wnt-1 and beta-catenin. Dev Biol 193:182-194. (Pubitemid 28113561)
9. Cho SH, Cepko CL. 2006. Wnt2b/beta-catenin-mediated canonical Wnt signaling determines the peripheral fates of the chick eye. Development 133:3167-3177.
10. Chow RL, Lang RA. 2001. Early eye development in vertebrates. Annu Rev Cell Dev Biol 17:255-296.
11. Coulombre AJ, Coulombre JL. 1957. The role of intraocular pressure in the development of the chick eye: III. Ciliary body. Am J Ophthalmol 44:85-93.
12. Davis-Silberman N, Ashery-Padan R. 2008. Iris development in vertebrates; genetic and molecular considerations. Brain Res 1192:17-28. (Pubitemid 351199479)
13. Del Sal G, Ruaro ME, Philipson L, Schneider C. 1992. The growth arrest-specific gene, gas1, is involved in growth suppression. Cell 70:595-607.
14. Dias da Silva MR, Tiffin N, Mima T, Mikawa T, Hyer J. 2007. FGF-mediated induction of ciliary body tissue in the chick eye. Dev Biol 304:272-285. (Pubitemid 46399687)
15. Diehn JJ, Diehn M, Marmor MF, Brown PO. 2005. Differential gene expression in anatomical compartments of the human eye. Genome Biol 6:R74.
16. Dreyer SD, Zhou G, Baldini A, Winterpacht A, Zabel B, Cole W, Johnson RL, Lee B. 1998. Mutations in LMX1B cause abnormal skeletal patterning and renal dysplasia in nail patella syndrome. Nat Genet 19:47-50. (Pubitemid 28242021)
17. Duester G. 2000. Families of retinoid dehydrogenases regulating vitamin A function: production of visual pigment and retinoic acid. Eur J Biochem 267:4315-4324. (Pubitemid 30461062)
18. Escribano J, Coca-Prados M. 2002. Bioinformatics and reanalysis of subtracted expressed sequence tags from the human ciliary body: Identification of novel biological functions. Mol Vis 8:315-332. (Pubitemid 36153622)
19. Fan X, Molotkov A, Manabe S, Donmoyer CM, Deltour L, Foglio MH, Cuenca AE, Blaner WS, Lipton SA, Duester G. 2003. Targeted disruption of Aldh1a1 (Raldh1) provides evidence for a complex mechanism of retinoic acid synthesis in the developing retina. Mol Cell Biol 23:4637-4648. (Pubitemid 36734752)
20. Fantin VR, Wang Q, Lienhard GE, Keller SR. 2000. Mice lacking insulin receptor substrate 4 exhibit mild defects in growth, reproduction, and glucose homeostasis. Am J Physiol Endocrinol Metab 278:E127-133. (Pubitemid 30101929)
21. Fu X, Sun H, Klein WH, Mu X. 2006. Beta-catenin is essential for lamination but not neurogenesis in mouse retinal development. Dev Biol 299:424-437. (Pubitemid 44635450)
22. Gage PJ, Rhoades W, Prucka SK, Hjalt T. 2005. Fate maps of neural crest and mesoderm in the mammalian eye. Invest Ophthalmol Vis Sci 46:4200-4208. (Pubitemid 44264623)
23. Giovannone B, Scaldaferri ML, Federici M, Porzio O, Lauro D, Fusco A, Sbraccia P, Borboni P, Lauro R, Sesti G. 2000. Insulin receptor substrate (IRS) transduction system: distinct and overlapping signaling potential. Diabetes Metab Res Rev 16:434-441. (Pubitemid 32066549)
24. Gould DB, Smith RS, John SW. 2004. Anterior segment development relevant to glaucoma. Int J Dev Biol 48:1015-1029.
25. Halfter W, Willem M, Mayer U. 2005. Basement membrane-dependent survival of retinal ganglion cells. Invest Ophthalmol Vis Sci 46:1000-1009. (Pubitemid 41321038)
26. Hamburger V, Hamilton HL. 1992. A series of normal stages in the development of the chick embryo. 1951. Dev Dyn 195:231-272.
27. Idrees F, Vaideanu D, Fraser SG, Sowden JC, Khaw PT. 2006. A review of anterior segment dysgeneses. Surv Ophthalmol 51:213-231.
28. Imaizumi M, Kuwabara T. 1971. Development of the rat iris. Invest Ophthalmol 10:733-744.
29. Jasoni C, Hendrickson A, Roelink H. 1999. Analysis of chicken Wnt-13 expression demonstrates coincidence with cell division in the developing eye and is consistent with a role in induction. Dev Dyn 215:215-224. (Pubitemid 29310069)
30. Khoo KM, Chang CF. 1999. Characterization and localization of CD38 in the vertebrate eye. Brain Res 821:17-25.
31. Kubo F, Takeichi M, Nakagawa S. 2003. Wnt2b controls retinal cell differentiation at the ciliary marginal zone. Development 130:587-598. (Pubitemid 36231277)
32. Kubota R, McGuire C, Dierks B, Reh TA. 2004. Identification of ciliary epithelial-specific genes using subtractive libraries and cDNA arrays in the avian eye. Dev Dyn 229:529-540. (Pubitemid 38294902)
33. Larsen M, Ressler SJ, Lu B, Gerdes MJ, McBride L, Dang TD, Rowley DR. 1998. Molecular cloning and expression of ps20 growth inhibitor. A novel WAP-type "four-disulfide core" domain protein expressed in smooth muscle. J Biol Chem 273:4574-4584.
34. Liu H, Mohamed O, Dufort D, Wallace VA. 2003. Characterization of Wnt signaling components and activation of the Wnt canonical pathway in the murine retina. Dev Dyn 227:323-334. (Pubitemid 36828753)
35. Liu H, Xu S, Wang Y, Mazerolle C, Thurig S, Coles BL, Ren JC, Taketo MM, van der Kooy D, Wallace VA. 2007. Ciliary margin transdifferentiation from neural retina is controlled by canonical Wnt signaling. Dev Biol 308:54-67. (Pubitemid 47087776)
36. Martinez-Morales JR, Signore M, Acampora D, Simeone A, Bovolenta P. 2001. Otx genes are required for tissue specification in the developing eye. Development 128:2019-2030. (Pubitemid 32600465)
37. McIntosh I, Dreyer SD, Clough MV, Dunston JA, Eyaid W, Roig CM, Montgomery T, Ala-Mello S, Kaitila I, Winterpacht A, Zabel B, Frydman M, Cole WG, Francomano CA, Lee B. 1998. Mutation analysis of LMX1B gene in nail-patella syndrome patients. Am J Hum Genet 63:1651-1658. (Pubitemid 30415727)
38. Monaghan AP, Davidson DR, Sime C, Graham E, Baldock R, Bhattacharya SS, Hill RE. 1991. The Msh-like homeobox genes define domains in the developing vertebrate eye. Development 112:1053-1061. (Pubitemid 21900306)
39. Morimura N, Tezuka Y, Watanabe N, Yasuda M, Miyatani S, Hozumi N, Tezuka Ki K. 2001. Molecular cloning of POEM: a novel adhesion molecule that interacts with alpha8beta1 integrin. J Biol Chem 276:42172-42181.
40. Murtaugh LC, Chyung JH, Lassar AB. 1999. Sonic hedgehog promotes somitic chondrogenesis by altering the cellular response to BMP signaling. Genes Dev 13:225-237.
41. Nagai T, Aruga J, Takada S, Gunther T, Sporle R, Schughart K, Mikoshiba K. 1997. The expression of the mouse Zic1, Zic2, and Zic3 gene suggests an essential role for Zic genes in body pattern formation. Dev Biol 182:299-313. (Pubitemid 27145481)
42. Nakagawa T, Guichard A, Castro CP, Xiao Y, Rizen M, Zhang HZ, Hu D, Bang A, Helms J, Bier E, Derynck R. 2005. Characterization of a human rhomboid homolog, p100hRho/RHBDF1, which interacts with TGF-alpha family ligands. Dev Dyn 233:1315-1331. (Pubitemid 40995129)
43. Napier HR, Kidson SH. 2007. Molecular events in early development of the ciliary body: a question of folding. Exp Eye Res 84:615-625.
44. Oklu R, Hesketh R. 2000. The latent transforming growth factor beta binding protein (LTBP) family. Biochem J 352 Pt 3:601-610.
45. Pressman CL, Chen H, Johnson RL. 2000. LMX1B, a LIM homeodomain class transcription factor, is necessary for normal development of multiple tissues in the anterior segment of the murine eye. Genesis 26:15-25.
46. Rowan S, Chen CM, Young TL, Fisher DE, Cepko CL. 2004. Transdifferentiation of the retina into pigmented cells in ocular retardation mice defines a new function of the homeodomain gene Chx10. Development 131:5139-5152. (Pubitemid 39485369)
47. Sun G, Asami M, Ohta H, Kosaka J, Kosaka M. 2006. Retinal stem/progenitor properties of iris pigment epithelial cells. Dev Biol 289:243-252. (Pubitemid 41804102)
48. Thut CJ, Rountree RB, Hwa M, Kingsley DM. 2001. A large-scale in situ screen provides molecular evidence for the induction of eye anterior segment structures by the developing lens. Dev Biol 231:63-76. (Pubitemid 32198387)
49. Tietjen I, Rihel JM, Cao Y, Koentges G, Zakhary L, Dulac C. 2003. Single-cell transcriptional analysis of neuronal progenitors. Neuron 38:161-175. (Pubitemid 36555644)
50. Trimarchi JM, Stadler MB, Roska B, Billings N, Sun B, Bartch B, Cepko CL. 2007. Molecular heterogeneity of developing retinal ganglion and amacrine cells revealed through single cell gene expression profiling. J Comp Neurol 502:1047-1065. (Pubitemid 46806635)
51. Trimarchi JM, Stadler MB, Cepko CL. 2008. Individual retinal progenitor cells display extensive heterogeneity of gene expression. PLoS ONE 3:e1588.
52. Tropepe V, Coles BL, Chiasson BJ, Horsford DJ, Elia AJ, McInnes RR, van der Kooy D. 2000. Retinal stem cells in the adult mammalian eye. Science 287:2032-2036. (Pubitemid 30158683)
53. Urban S. 2006. Rhomboid proteins: conserved membrane proteases with divergent biological functions. Genes Dev 20:3054-3068. (Pubitemid 44790621)
54. Vollrath D, Jaramillo-Babb VL, Clough MV, McIntosh I, Scott KM, Lichter PR, Richards JE. 1998. Loss-of-function mutations in the LIM-homeodomain gene, LMX1B, in nail-patella syndrome. Hum Mol Genet 7:1091-1098. (Pubitemid 28306872)
55. Volpe P, Biral D, Pizzo P, Salviati G, Margreth A. 1993. Ontogenesis of chick iris intrinsic muscles: evidence for a smooth-to-striated muscle transition. Dev Biol 159:441-449. (Pubitemid 23334070)
56. Zemel S, Bartolomei MS, Tilghman SM. 1992. Physical linkage of two mammalian imprinted genes, H19 and insulinlike growth factor 2. Nat Genet 2:61-65.
57. Zhao S, Chen Q, Hung FC, Overbeek PA. 2002. BMP signaling is required for development of the ciliary body. Development 129:4435-4442. (Pubitemid 35203727)
58. Ziegler WH, Liddington RC, Critchley DR. 2006. The structure and regulation of vinculin. Trends Cell Biol 16:453-460.