Detection of retinal metabolic stress resulting from central serous retinopathy

Retina

Volumn 29, Issue 8, 2009, Pages 1162-1166

  Field, Matthew G ^a   Elner, Victor M ^a,b   Park, Seung ^a   Hackel, Richard ^a   Heckenlively, John R ^a   Elner, Susan G ^a   Petty, Howard R ^a  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^b UNIVERSITY OF MICHIGAN   (United States)

Author keywords

Autofluorescence; Central serous chorioretinopathy; Central serous retinopathy; Flavoprotein fluorescence; Flavoproteins; Metabolic stress; Mitochondrial dysfunction; Retinal stress

Indexed keywords

ADULT; ARTICLE; CASE REPORT; CENTRAL SEROUS RETINOPATHY; CONTROLLED STUDY; FLUORESCENCE ANGIOGRAPHY; HUMAN; IMAGE ANALYSIS; IMAGE INTENSIFIER; MALE; METABOLIC STRESS; OPHTHALMOSCOPY; VISUAL ACUITY;

ADULT; BIOLOGICAL MARKERS; CENTRAL SEROUS CHORIORETINOPATHY; FLAVOPROTEINS; FLUORESCEIN ANGIOGRAPHY; FLUORESCENCE; HUMANS; MALE; OXIDATIVE STRESS; REPRODUCIBILITY OF RESULTS; RETINA;

EID: 70349085002     PISSN: 0275004X     EISSN: None     Source Type: Journal    
DOI: 10.1097/IAE.0b013e3181a3b923     Document Type: Article

References (29)

1. Wang M, Munch IC, Hasler PW, Prünte C, Larsen M. Central serous chorioretinopathy. Acta Ophthalmol 2008;86:126-145.
2. Piccolino FC, Borgia L. Central serous chorioretinopathy and indocyanine green angiography. Retina 1994;14:231-242.
3. Prunte C, Flammer J. Choroidal capillary and venous congestion in central serous retinopathy. Am J Ophthalmol 1996;121: 26-34.
4. Mitarai K, Gomi F, Tano Y. Three-dimensional optical coherence tomographic findings in central serous chorioretinopathy. Graefes Arch Clin Exp Ophthalmol 2006;244:1415-1420.
5. Ojima Y, Hangai M, Sasahara M, et al. Three-dimensional imaging of the foveal photoreceptor layer in central serous chorioretinopathy using high-speed optical coherence tomography. Ophthalmology 2007;114:2197-2207.
6. Moschos M, Brouzas D, Koutsandrea C, et al. Assessment of central serous chorioretinopathy by optical coherence tomography and multifocal electroretinography. Ophthalmologica 2007;221:292-298.
7. Fujimoto H, Gomi F, Wakabayashi T, Sawa M, Tsujikawa M, Tano Y. Morphologic changes in acute central serous chori-oretinopathy evaluated by fourier-domain optical coherence tomography. Ophthalmology 2008;115:1494-1500.
8. von Ruckmann A, Fitzke FW, Fan J, Halfyard A, Bird AC. Abnormalities of fundus autofluorescence in central serous retinopathy. Am J Ophthalmol 2002;133:780-786.
9. Framme C, Walter A, Gabler B, Roider J, Sachs HG, Gabel VP. Fundus autofluorescence in acute and chronic-recurrent central serous chorioretinopathy. Acta Ophthalmol Scand 2005:83;161-167.
10. Eandi CM, Ober M, Iranmanesh R, Peiretti E, Yannuzzi LA. Acute central serous chorioretinopathy and fundus autofluorescence. Retina 2005;25:989-993.
11. Spaide RF, Klancnik JM Jr. Fundus autofluorescence and central serous chorioretinopathy. Ophthalmology 2005;112: 825-833.
12. Durnaief JL, Dentchev T, Ying G-S, Milam AH. The role of apoptosis in age-related macular degeneration. Arch Ophthalmol 2002;120:1435-1442.
13. Podesta F, Romeo G, Liu WH, et al. Bax is increased in the retina of diabetic subjects and in association with pericyte apoptosis in vivo and in vitro. Am J Pathol 2000;156:1025-1032.
14. Kerrigan LA, Zack DJ, Quigley HA, Smith SD, Pease ME. TUNEL-positive ganglion cells in human primary open-angle glaucoma. Arch Ophthalmol 1997;115:1031-1035.
15. Du Y, Miller CM, Kern TS. Hyperglycemia increases mito-chondrial superoxide in retina and retinal cells. Free Radic Biol Med 2003;35:1491-1499.
16. Ning X, Baoyu Q, Yuzhen L, Shuli S, Reed E, Li QQ. Neuro-optic cell apoptosis and microangiopathy in KKAY mouse retina. Int J Mol Med 2004;13:87-92.
17. Benson RC, Meyer RA, Zaruba ME, McKhann GM. Cellular autofluorescence-is it due to flavins? J Histochem Cytochem 1979;27:44-48.
18. Kindzelskii A, Petty HR. Fluorescence spectroscopic detection of mitochondrial flavoprotein redox oscillations and transient reduction of the NADPH oxidase-associated flavoprotein in leukocytes. Eur Biophys J 2004;33:291-299.
19. Reinert KC, Dunbar RL, Wangcai G, Gang C, Ebner TJ. Flavoprotein autofluorescence imaging of neuronal activation in the cerebellar cortex in vivo. J Neurophysiol 2004;92:199-211.
20. Ranji M, Kanemoto S, Matsubara M, et al. Fluorescence spectroscopy and imaging of myocardial apoptosis. J Biomed Opt 2006;11:064036.
21. Elner VM, Park S, Cornblath W, Hackel R, Petty HR. Fla-voprotein autofluorescence detection of early ocular dysfunction. Arch Ophthalmol 2008;126:259-260.
22. Field MG, Elner VM, Puro DG, et al. Rapid, non-invasive detection of diabetes-induced retinal metabolic stress. Arch Ophthalmol 2008;126:934-938.
23. Elner SG, Elner VM, Field MG, Park S, Heckenlively JR, Petty HR. Retinal flavoprotein autofluorescence as a measure of retinal health. Trans Am Ophthalmol Soc 2008;106:215-224.
24. Arroyo JG, Yang L, Bula D, Chen DF. Photoreceptor apopto-sis in human retinal detachment. Am J Ophthalmol 2005;139: 605-610.
25. Chang CJ, Lai WW, Edward DP, Tso MO. Apoptotic photoreceptor cell death after traumatic retinal detachment in human. Arch Ophthalmol 1995;113:880-886.
26. Hisatomi T, Sakamoto T, Goto Y, et al. Critical role of photoreceptor apoptosis in functional damage after retinal detachment. Curr Eye Res 2002;24:161-172.
27. Ranty ML, Carpentier S, Cournot M, et al. Ceramide production associated with retinal apoptosis after retinal detachment. Graefes Arch Clin Exp Ophthalmol 2009;247:215-224.
28. Szalai G, Krishnamurthy R, Hajnoczky G. Apoptosis driven by IP(3)-linked mitochondrial calcium signals. EMBO J 1999;18: 6349-6361.
29. Pacher P, Hajnoczky G. Propagation of the apoptotic signal by mitochondrial waves. EMBO J 2001;20:4107-4121.