A modeling study of the effect of environmental ionic valence on the mechanical characteristics of pH-electrosensitive hydrogel

Acta Biomaterialia

Volumn 5, Issue 8, 2009, Pages 2920-2928

  Luo, Rongmo ^a   Li, Hua ^a  

^a NANYANG TECHNOLOGICAL UNIVERSITY   (Singapore)

Author keywords

Chemo electromechanical model; Combined stimuli of solution pH and electric voltage; Ionic valency; Monovalent multivalent ion exchange; pH electrosensitive hydrogel

Indexed keywords

CHARGE DENSITY; DEFORMATION; ELECTRIC FIELDS; ELECTRIC POTENTIAL; ION EXCHANGE; NONLINEAR EQUATIONS; OSMOSIS; PH EFFECTS;

CHEMO-ELECTROMECHANICAL MODEL; COMBINED STIMULI; COMBINED STIMULUS OF SOLUTION PH AND ELECTRIC VOLTAGE; ELECTRIC VOLTAGE; ELECTROMECHANICAL MODELING; IONIC VALENCY; MONOVALENT-MULTIVALENT ION EXCHANGE; MULTIVALENT IONS; PH-ELECTROSENSITIVE HYDROGEL; SOLUTION PH; VALENCIES;

HYDROGELS;

ARTICLE; ELECTRIC POTENTIAL; ELECTROSTIMULATION; HYDROGEL; ION EXCHANGE; MATHEMATICAL ANALYSIS; MATHEMATICAL MODEL; MECHANICAL STRESS; OSMOTIC PRESSURE; PH; PRIORITY JOURNAL; RIGIDITY;

BIOCOMPATIBLE MATERIALS; COMPUTER SIMULATION; ELASTIC MODULUS; ELECTROCHEMISTRY; ELECTROMAGNETIC FIELDS; HYDROGELS; HYDROGEN-ION CONCENTRATION; IONS; MODELS, CHEMICAL; OSMOTIC PRESSURE; STATIC ELECTRICITY; TENSILE STRENGTH;

EID: 70349084597     PISSN: 17427061     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.actbio.2009.04.009     Document Type: Article

References (45)

1. Li H., Ng T.Y., Yew Y.K., and Lam K.Y. Modeling and simulation of the swelling behavior of pH-stimulus-responsive hydrogels. Biomacromolecules 6 (2005) 109-120
2. Gutowska A., Bae Y.H., Jacobs H., Jan F.J., and Kim S.W. Thermosensitive interpenetrating polymer networks: synthesis, characterization, and macromolecular release. Macromolecules 27 (1994) 4167-4175
3. Shin B.C., Kim S.S., Ko J.K., Jegul J., and Lee B.M. Gradual phase transition of poly(N-isopropylacrylamide-co-acrylic acid) gel induced by electric current. Eur Polym J 39 (2003) 579-584
4. Qiu Y., and Park K. Environment-sensitive hydrogels for drug delivery. Adv Drug Deliv Rev 53 (2001) 321-339
5. Jin X., and Hsieh Y.L. PH-responsive swelling behavior of poly(vinyl alcohol)/poly(acrylic acid) bi-component fibrous hydrogel membranes. Polymer 46 (2005) 5149-5160
6. Sawai T., Shinohara H., Ikariyama Y., and Aizawa M. Electrical control of the volume of pH-sensitive micro-gels. J Electroanal Chem 297 (1991) 399-407
7. Shiga T., Hirose Y., Okada A., and Kurauchi T. Electric field-associated deformation of polyelectrolyte gel near a phase transition point. J Appl Polym Sci 46 (1992) 635-640
8. Kaetsu I., Uchida K., Morita Y., and Oku M. Synthesis of electro-responsive hydrogels by radiation polymerization of sodium acrylate. Int J Radiat Appl Inst C Radiat Phys Chem 40 (1992) 157-160
9. Kaetsu I. Signal responsive chemical delivery systems by radiation techniques and the use for brain research. Radiat Phys Chem 46 (1995) 247-256
10. Kim S.J., Lee C.K., Lee Y.M., Kim I.Y., and Kim S.I. Electrical/pH-sensitive swelling behavior of polyelectrolyte hydrogels prepared with hyaluronic acid-poly(vinyl alcohol) interpenetrating polymer networks. React Funct Polym 55 (2003) 291-298
11. Kim S.J., Yoon S.G., Lee S.M., Lee S.H., and Kim S.I. Electric sensitivity behavior of a hydrogel composed of polymethacrylic acid/poly(vinyl alcohol). J Appl Polym Sci 91 (2004) 3613-3617
12. Kim S.J., Lee C.K., and Kim S.I. Electrical/pH responsive properties of poly(2-acrylamido-2-methylpropane sulfonic acid)/hyaluronic acid hydrogels. J Appl Polym Sci 92 (2004) 1731-1736
13. El-Hag Ali A., El-Rehim A., Hegazy E.A., and Ghobashy M.M. Synthesis and electrical response of acrylic acid/vinyl sulfonic acid hydrogels prepared by γ-irradiation. Radiat Phys Chem 75 (2006) 1041-1046
14. Kim S.W., and Bae Y.H. Stimuli-modulated delivery systems. In: Amidon G.L., et al. (Ed). Transport processes in pharmaceutical systems (2000), Marcel Dekker, New York 547-573
15. Siegel R.A., and Firestone B.A. pH-Dependent equilibrium swelling properties of hydrophobic polyelectrolyte copolymer gels. Macromolecules 21 (1988) 3254-3259
16. Gupta P., Vermani K., and Garg S. Hydrogels: from controlled release to pH-responsive drug delivery. Drug Discovery Today 7 (2002) 569-579
17. Schneider S., and Linse P. Monte Carlo simulation of defect-free cross-linked polyelectrolyte gels. J Phys Chem B 107 (2003) 8030-8040
18. Tasaki I., Nakaye T., and Byrne P.M. Rapid swelling of neurons during synaptic transmission in the bullfrog sympathetic ganglion. Brain Res 331 (1985) 363-365
19. Tasaki I., and Byrne P.M. Large mechanical changes in the bullfrog olfactory bulb evoked by afferent fiber stimulation. Brain Res 475 (1988) 173-176
20. Tasaki I. Rapid structural changes in nerve fibers and cells associated with their excitation processes. Jpn J Physiol 49 (1999) 125-138
21. Horkay F., Tasaki I., and Basser P.J. Osmotic swelling of polyacrylate hydrogels in physiological salt solutions. Biomacromolecules 1 (2000) 84-90
22. Bajpai S.K., and Dubey S. In vitro dissolution studies for release of vitamin B12 from poly(N-vinyl-2-pyrrolidone-co-acrylic acid) hydrogels. React Funct Polym 62 (2005) 93-104
23. Bajpai S.K. Swelling-deswelling behavior of poly(acrylamide-co-maleic acid) hydrogels. J Appl Polym Sci 80 (2001) 2782-2789
24. Homma M., Seida Y., and Nakano Y. Effect of ions on the dynamic behavior of an electrodriven ionic polymer hydrogel membrane. J Appl Polym Sci 82 (2001) 76-80
25. Mika A.M., Childs R.F., and Dickson J.M. Salt separation and hydrodynamic permeability of a porous membrane filled with pH-sensitive gel. J Membr Sci 206 (2002) 19-30
26. Gu W.Y., Lai W.M., and Mow V.C. Transport of multi-electrolytes in charged hydrated biological soft tissue. Transport Porous Media 34 (1999) 143-157
27. Wallmersperger T., Kroplin B., Holdenried J., and Gulch R.W. A coupled multi-field formulation for ionic gels in electric fields. In: Bar-Cohen Y. (Ed). Proceedings of the SPIE 8th annual international symposium on smart structure and materials vol. 4329 (2001), SPIE, Newport Beach, CA 264-275
28. Zhou X., Hou Y.C., Sun S., and Mak A.F.T. Numerical simulation of the steady-state deformation of a smart hydrogel under an external electric field. Smart Mater Struct 11 (2002) 459-467
29. Li H., Chen J., and Lam K.Y. Multiphysical modeling and meshless simulation of electric-sensitive hydrogels. J Polym Sci B Polym Phys 42 (2004) 1514-1523
30. Tamagawa H., and Taya M. A theoretical prediction of the ions distribution in an amphoteric polymer gel. Mater Sci Eng A 285 (2000) 314-325
31. Li H., Yuan Z., Lam K.Y., Lee H.P., Chen J., Hanes J., et al. Model development and numerical simulation of electric-stimulus-responsive hydrogels subject to an externally applied electric field. Biosens Bioelectron 19 (2004) 1097-1107
32. Li H., Chen J., and Lam K.Y. A transient simulation to predict the kinetic behavior of hydrogels responsive to electric stimulus. Biomacromolecules 7 (2006) 1951-1959
33. Luo R.M., Li H., and Lam K.Y. Modeling and simulation of chemo-electro-mechanical behavior of pH-electric-sensitive hydrogel. Anal Bioanal Chem 389 (2007) 863-873
34. Li H., Luo R.M., Birgersson E., and Lam K.Y. Modeling of multiphase smart hydrogels responding to pH and electric voltage coupled stimuli. J Appl Phys 101 (2007) 114905-1-114905-7
35. Li H., Luo R.M., and Lam K.Y. Multiphysics modeling of electrochemomechanically smart microgels responsive to coupled pH-electric stimuli. Macromol Biosci 9 (2009) 287-297
36. Horst H.C., Timmer J.M.K., Robbertsen T., and Leenders J. Use of nanofiltration for concentration and demineralization in the dairy industry: model for mass transport. J Membr Sci 104 (1995) 205-218
37. Nikonenko V., Ebedev K.L., Manzanares J.A., and Pourcelly G. Modelling the transport of carbonic acid anions through anion-exchange membranes. Electrochim Acta 48 (2003) 3639-3650
38. Li H., Ng T.Y., Cheng J.Q., and Lam K.Y. Hermite-cloud: a novel true meshless method. Comput Mech 33 (2003) 30-41
39. Shiga T., and Kurauchi T. Deformation of polyelectrolyte gels under the influence of electric field. J Appl Polym Sci 39 (1990) 2305-2320
40. Yang Y.J., and Engberts J. Stimuli response of polysoap hydrogels in aqueous solution and DC electric fields. Colloids Surf A 169 (2000) 85-94
41. Tanaka T., Fillmore D., Sun S.T., Nishio I., Swislow G., and Shah A. Phase transitions in ionic gels. Phys Rev Lett 45 (1980) 1636-1639
42. Tanaka T., Nishio I., Sun S.T., and Nishio I. Collapse of gels in an electric field. Science 218 (1982) 467-469
43. Beebe D., Moore J., Bauer J., Yu Q., Liu R., Devadoss C., et al. Functional hydrogel structures for autonomous flow control inside microfluidic channels. Nature 404 (2000) 588-590
44. Ohimine I., and Tanaka T. Salt effects on the phase transition of ionic gels. J Chem Phys 77 (1982) 5725-5729
45. Yin W.S., Li J., Gu T.R., and Wu J.P. Design and synthesis of conducting secondary crosslinked interpenetrating polymer network. J Appl Polym Sci 63 (1997) 13-16