Two ATS recommended protocols for administration of methacholine are not equal

Journal of Asthma

Volumn 46, Issue 7, 2009, Pages 740-744

  Burke, Robert R ^a   Obeid, Imad M ^a   Williams, L Keoki ^a   Morris, Zachary Q ^a  

^a HENRY FORD HEALTH SYSTEM   (United States)

Author keywords

Airway responsiveness; Asthma; Bronchoprovocation; Methacholine; Spirometry

Indexed keywords

METHACHOLINE;

ADULT; AIRWAY; ARTICLE; ASTHMA; BREATHING; CLINICAL PROTOCOL; CONTROLLED STUDY; DIFFERENTIAL DIAGNOSIS; DOSE RESPONSE; DOSIMETRY; DRUG DELIVERY SYSTEM; DRUG DOSE COMPARISON; DRUG DOSE INCREASE; FEMALE; HUMAN; INTERMETHOD COMPARISON; MALE; MEDICAL SOCIETY; PROVOCATION TEST; RELIABILITY; TIDAL VOLUME; UNITED STATES;

ADMINISTRATION, INHALATION; ADULT; AGED; ASTHMA; BRONCHIAL HYPERREACTIVITY; BRONCHIAL PROVOCATION TESTS; CONFOUNDING FACTORS (EPIDEMIOLOGY); FALSE NEGATIVE REACTIONS; FEMALE; FORCED EXPIRATORY VOLUME; HUMANS; LOGISTIC MODELS; MALE; METHACHOLINE CHLORIDE; MIDDLE AGED; ODDS RATIO; VITAL CAPACITY;

EID: 70249148560     PISSN: 02770903     EISSN: 15324303     Source Type: Journal    
DOI: 10.1080/02770900903082589     Document Type: Article

References (18)

1. Mannino DM, Homa DM, Akinbami LJ, Moorman JE, Gwynn C, Redd S. Surveillance for asthma-United States, 1980-1999. MMWR Surveill Summ 2002; (SS01)51:1-13.
2. Crapo RO, Casaburi R, Coates AL, Enright PL, Hankinson JL, Irvin CG, MacIntyre NR, McKay RT, Wanger JS. Guidelines for methacholine and exercise challenge testing-1999. This official statement of the American Thoracic Society was adopted by the ATS Board of Directors, July 1999. Am J Respir Crit Care Med 2000; 161:309-329.
3. Cockcroft DW, Davis BE, Todd DC, Smycniuk AJ. Methacholine challenge: comparison of two methods. Chest 2005; 127:839-844.
4. Prieto L, Ferrer A, Domenech J, Perez-Frances C. Effect of challenge method on sensitivity, reactivity, and maximal response to methacholine. Ann Allergy Asthma Immunol 2006; 97:175-181.
5. Allen ND, Davis BE, Hurst TS, Cockcroft DW. Difference between dosime-ter and tidal breathing methacholine challenge: contributions of dose and deep inspiration bronchoprotection. Chest 2005; 128:4018-4023.
6. Todd DC, Davis BE, Hurst TS, Cockcroft DW. Dosimeter methacholine challenge: comparison of maximal versus submaximal inhalations. J Allergy Clin Immunol 2004; 114:517-519.
7. Prieto L, Lopez V, Llusar R, Rojas R, Marin J. Differences in the response to methacholine between the tidal breathing and dosimeter methods: influence of the dose of bronchoconstrictor agent delivered to the mouth. Chest 2008; 134:699-703.
8. Miller MR, Hankinson J, Brusasco V, Burgos F, Casaburi R, Coates A, Crapo R, Enright P, van der Grinten CPM, Gustafsson P, Jensen R, Johnson DC, MacIntyre N, McKay R, Navajas D, Pedersen OF, Pellegrino R, Viegi G, Wanger J. ATS/ERS Task Force: Standardisation of lung function testing. Standardisation of spirometry. Eur Respir J 2005; 26:319-338.
9. Hankinson JL, Odencrantz JR, Fedan KB. Spirometric reference values from a sample of the general U.S. population. Am J Respir Crit Care Med 1999; 159:179-187.
10. Toelle BG, Peat JK, Salome CM, Crane J, McMillan D, Dermand J, D'Souza W, Wookcock AJ. Comparison of two epidemiological protocols for measuring airway responsiveness and allergic sensitivity in adults. Eur Respir J 1994; 7:1798-1804.
11. Bennett JB, Davies RJ. A comparison of histamine and methacholine bronchial challenges using the DeVilbiss 646 nebulizer and the Rosenthal-French dosimeter. Br J Dis Chest 1987; 81:252-259.
12. Knox AJ, Wisniewski A, Cooper S, Cooper S, Tattersfield AE. A comparison of the Yan and a dosimeter method for methacholine challenge in experienced and inexperienced subjects. Eur Respir J 1991; 4:497-502.
13. Asher MI, Bertrand JM, Beaudry PH, Coates AL. Histamine inhalation challenge in children: a comparison of two methods. Ann Allergy 1983; 50:389-392.
14. Hargreave FE, Ryan G, Thomson NC, O'Byrne PM, Latimer K, Juniper EF. Bronchial responsiveness to histamine or methacholine in asthma: measurement and clinical significance. J Allergy Clin Immunol 1981; 68:347-355.
15. Khalid, I, Obeid, I., DiGiovine B, Khalid U, Morris ZQ. Predictive Value of Sgaw, FEF25-75, and FEV1 for Development of Asthma after a Negative Methacholine Challenge Test. Journal of Asthma 2009, 46:284-290.
16. Schwartz J, Schindler C, Zemp E, Perruchoud AP, Zellweger JP, Wuthrich B, Leuenberger P, Ackermann-Liebrich U. Predictors of methacholine responsiveness in a general population. Chest 2002; 122:812-820.
17. Paoletti P, Carrozzi L, Viegi G, Modena P, Ballerin L, DiPede F, Grado L, Baldacci S, Pedreschi M, Vellutini M. Distribution of bronchial responsiveness in a general population: effect of sex, age, smoking, and level of pulmonary function. Am J Respir Crit Care Med 1995; 151:1770-1777.
18. Joseph CL, Ownby DR, Peterson EL, Johnson CC. Racial differences in physiologic parameters related to asthma among middle-class children. Chest 2000; 117:1336-1344.