7-Chloroarctinone-b as a new selective PPARγ antagonist potently blocks adipocyte differentiation

Acta Pharmacologica Sinica

Volumn 30, Issue 9, 2009, Pages 1351-1358

  Li, Yong Tao ^a   Li, Li ^a   Chen, Jing ^b   Hu, Tian Cen ^b   Huang, Jin ^a   Guo, Yue Wei ^b   Jiang, Hua Liang ^a,b   Shen, Xu ^a,b  

^a EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^b SHANGHAI INSTITUTE OF MATERIA MEDICA   (China)

Author keywords

Adipocyte differentiation; Antagonist; Peroxisome proliferator activated receptor; Recruitment of the coactivator; Surface plasmon resonance

Indexed keywords

7 CHLOROARCTINONE B; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA ANTAGONIST; RETINOID X RECEPTOR ALPHA; ROSIGLITAZONE; UNCLASSIFIED DRUG;

ADIPOCYTE; ANIMAL CELL; ARTICLE; BINDING AFFINITY; CELL DIFFERENTIATION; CONTROLLED STUDY; DRUG MECHANISM; DRUG RECEPTOR BINDING; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; OBESITY; SURFACE PLASMON RESONANCE;

3T3-L1 CELLS; ADIPOCYTES; ADIPOGENESIS; ANIMALS; CELL DIFFERENTIATION; DIMERIZATION; HUMANS; MICE; PPAR GAMMA; SURFACE PLASMON RESONANCE; THIOPHENES; TRANSCRIPTIONAL ACTIVATION; TWO-HYBRID SYSTEM TECHNIQUES;

EID: 70249146489     PISSN: 16714083     EISSN: 17457254     Source Type: Journal    
DOI: 10.1038/aps.2009.113     Document Type: Article

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