Biocatalytic synthesis of ethyl (R)-2-hydroxy-4-phenylbutyrate with Candida krusei SW2026: A practical process for high enantiopurity and product titer

Process Biochemistry

Volumn 44, Issue 11, 2009, Pages 1270-1275

  Zhang, Wen ^a   Ni, Ye ^a   Sun, Zhihao ^a   Zheng, Pu ^a   Lin, Wenqing ^b   Zhu, Po ^b   Ju, Nianfeng ^b  

^a JIANGNAN UNIVERSITY   (China)

^b Porton Corporation   (China)

Author keywords

Asymmetric reduction; Biosynthesis; Candida krusei; Ethyl (R) 2 hydroxy 4 phenylbutyrate ((R) HPBE); Ethyl 2 oxo 4 phenylbutyrate (OPBE)

Indexed keywords

ANGIOTENSIN-CONVERTING ENZYME; AQUEOUS MEDIUM; ASYMMETRIC REDUCTION; BIOCATALYTIC SYNTHESIS; BIOTRANSFORMATION REACTIONS; BIPHASIC SYSTEMS; CANDIDA KRUSEI; CO-SUBSTRATE; ENANTIOMERIC EXCESS; ENANTIOPURITY; ETHYL (R)-2-HYDROXY-4-PHENYLBUTYRATE ((R)-HPBE); ETHYL 2-OXO-4-PHENYLBUTYRATE (OPBE); FED BATCHES; GREEN CHEMISTRY; LARGE-SCALE PRODUCTION; MICROBIAL REDUCTION; OPTIMAL CONDITIONS; PHTHALATES; PRACTICAL PROCESS; PRODUCT CONCENTRATION; REDUCTION PROCESS;

BIOCHEMISTRY; BIOSYNTHESIS; ESTERS; GLUCOSE;

SUBSTRATES;

ISSATCHENKIA ORIENTALIS;

EID: 70249098768     PISSN: 13595113     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.procbio.2009.07.011     Document Type: Article

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