Screening of species of the endophytic fungus Phomopsis for the production of the anticancer drug taxol

Biotechnology and Applied Biochemistry

Volumn 54, Issue 1, 2009, Pages 21-30

  Kumaran, Rangarajulu Senthil ^a,b   Hur, Byung Ki ^a  

^a Inha University   (South Korea)

^b Korea Advanced Institute of Science and Technology (KAIST)   (South Korea)

Author keywords

Anticancer drug; Endophytic fungus; Phomopsis; Taxadiene synthase gene (ts); Taxol

Indexed keywords

ANTICANCER DRUG; ENDOPHYTIC FUNGUS; PHOMOPSIS; TAXADIENE SYNTHASE GENE (TS); TAXOL;

CELL DEATH; CHROMATOGRAPHIC ANALYSIS; ENZYMES; STRAIN;

FUNGI;

GENE PRODUCT; GINKGO BILOBA EXTRACT; LARIX LEPTOLEPIS EXTRACT; PACLITAXEL; PLANT EXTRACT; TAXADIENE SYNTHASE; TAXUS CUSPIDATA EXTRACT; UNCLASSIFIED DRUG; ANTINEOPLASTIC AGENT; FUNGAL PROTEIN; ISOMERASE; TAXA 4(5),11(12) DIENE SYNTHASE; TAXA-4(5),11(12)-DIENE SYNTHASE;

APOPTOSIS; ARTICLE; CANCER CELL; CHROMATOGRAPHY; CONTROLLED STUDY; CYTOTOXICITY; ENDOPHYTE; FUNGUS; FUNGUS ISOLATION; GENE SEQUENCE; GENETIC CONSERVATION; GENETIC ENGINEERING; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; LARIX LEPTOLEPIS; NONHUMAN; NUCLEOTIDE SEQUENCE; PHOMOPSIS; PLANT LEAF; POLYMERASE CHAIN REACTION; SCREENING TEST; SPECTROSCOPY; TAXOMYCES ANDREANAE; TAXUS CUSPIDATA; ASCOMYCETES; BIOSYNTHESIS; CHEMISTRY; CYTOLOGY; DRUG EFFECT; DRUG SCREENING; FUNGUS SPORE; GENETICS; GINKGO BILOBA; INFRARED SPECTROPHOTOMETRY; ISOLATION AND PURIFICATION; LARIX; METABOLISM; MICROBIOLOGY; TAXUS; THIN LAYER CHROMATOGRAPHY; TUMOR CELL LINE; ULTRASTRUCTURE; ULTRAVIOLET SPECTROPHOTOMETRY;

FUNGI; GINKGO BILOBA; LARIX KAEMPFERI; PHOMOPSIS; PSEUDOLARIX KAEMPFERI; TAXUS CUSPIDATA;

ANTINEOPLASTIC AGENTS; APOPTOSIS; ASCOMYCOTA; CELL LINE, TUMOR; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CHROMATOGRAPHY, THIN LAYER; DRUG SCREENING ASSAYS, ANTITUMOR; FUNGAL PROTEINS; GINKGO BILOBA; HUMANS; ISOMERASES; LARIX; PACLITAXEL; POLYMERASE CHAIN REACTION; SPECTROPHOTOMETRY, INFRARED; SPECTROPHOTOMETRY, ULTRAVIOLET; SPORES, FUNGAL; TAXUS;

EID: 70149123098     PISSN: 08854513     EISSN: None     Source Type: Journal    
DOI: 10.1042/BA20080110     Document Type: Article

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