A short and efficient synthesis of (-)-7-methylomuralide, a potent proteasome inhibitor

Journal of the American Chemical Society

Volumn 131, Issue 16, 2009, Pages 5746-5747

  Shenvi, Ryan A ^a   Corey, E J ^a  

^a HARVARD UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ABSOLUTE STEREOCHEMISTRY; ALDOL REACTIONS; EFFICIENT SYNTHESIS; GROUP CONTROL; PROTEASOME INHIBITORS; SCALABLE SYNTHESIS; TANDEM REACTION; TARGET MOLECULE;

STEREOCHEMISTRY;

SYNTHESIS (CHEMICAL);

7 METHYLOMURALIDE; PROTEASOME INHIBITOR; UNCLASSIFIED DRUG; GLYCINE; LACTONE; METHYLOMURALIDE; N-TRICHLOROETHOXYCARBONYL GLYCINE; PROTEINASE INHIBITOR;

ALDOL REACTION; ARTICLE; CHIRALITY; CONTROLLED STUDY; CRYSTAL STRUCTURE; DRUG SYNTHESIS; STEREOCHEMISTRY; X RAY CRYSTALLOGRAPHY; ANALOGS AND DERIVATIVES; CHEMISTRY; STEREOISOMERISM; SYNTHESIS;

GLYCINE; LACTONES; PROTEASE INHIBITORS; STEREOISOMERISM;

EID: 70149121498     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja901400q     Document Type: Article

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