-
1
-
-
43249095919
-
Tumor angiogenesis
-
Kerbel RS. Tumor angiogenesis. N Engl J Med 2008;358:2039-2049
-
(2008)
N Engl J Med
, vol.358
, pp. 2039-2049
-
-
Kerbel, R.S.1
-
2
-
-
0025312728
-
A genetic model for colorectal tumorigenesis
-
Fearon ER, Vogelstein B. A genetic model for colorectal tumorigenesis. Cell 1992;61:759-767
-
(1992)
Cell
, vol.61
, pp. 759-767
-
-
Fearon, E.R.1
Vogelstein, B.2
-
3
-
-
0342264492
-
Concurrent and independent genetic alterations in the stromal and epithelial cells of mammary carcinoma: Implications for tumorigenesis
-
Moinfar F, Man YG, Arnould L, Bratthauer GL, Ratschek M, Tavassoli FA. Concurrent and independent genetic alterations in the stromal and epithelial cells of mammary carcinoma: implications for tumorigenesis. Cancer Res 2000;60:2562-2566 (Pubitemid 30262453)
-
(2000)
Cancer Research
, vol.60
, Issue.9
, pp. 2562-2566
-
-
Moinfar, F.1
Man, Y.G.2
Arnould, L.3
Bratthauer, G.L.4
Ratschek, M.5
Tavassoli, F.A.6
-
4
-
-
33845931347
-
Identification of alterations in DNA copy number in host stromal cell during tumor progression
-
DOI 10.1073/pnas.0609635104
-
Pelham RJ, Rodgers L, Hall I, et al. Identification of alterations in DNA copy number in host stromal cells during tumor progression. Proc Natl Acad Sci U S A 2006;103:19848-19853 (Pubitemid 46037519)
-
(2006)
Proceedings of the National Academy of Sciences of the United States of America
, vol.103
, Issue.52
, pp. 19848-19853
-
-
Pelham, R.J.1
Rodgers, L.2
Hall, I.3
Lucito, R.4
Nguyen, K.C.Q.5
Navin, N.6
Hicks, J.7
Mu, D.8
Powers, S.9
Wigler, M.10
Botstein, D.11
-
5
-
-
0035445625
-
Genetic model of multi-step breast carcinogenesis involving the epithelium and stroma: Clues to tumour-microenvironment interactions
-
Kurose K, Hoshaw-Woodard S, Adeyinka A, Lemeshow S, Watson PH, Eng C. Genetic model of multi-step breast carcinogenesis involving the epithelium and stroma: clues to tumour-microenvironment interactions. Hum Mol Genet 2001;10:1907-1913 (Pubitemid 32910535)
-
(2001)
Human Molecular Genetics
, vol.10
, Issue.18
, pp. 1907-1913
-
-
Kurose, K.1
Hoshaw-Woodard, S.2
Adeyinka, A.3
Lemeshow, S.4
Watson, P.H.5
Eng, C.6
-
6
-
-
0036843937
-
Frequent somatic mutations in PTEN and TP53 are mutually exclusive in the stroma of breast carcinomas
-
DOI 10.1038/ng1013
-
Kurose K, Gilley K, Matsumoto S, Watson PH, Zhou XP, Eng C. Frequent somatic mutations in PTEN and TP53 are mutually exclusive in the stroma of breast carcinomas. Nat Genet 2002;32:355-357 (Pubitemid 35266108)
-
(2002)
Nature Genetics
, vol.32
, Issue.3
, pp. 355-357
-
-
Kurose, K.1
Gilley, K.2
Matsumoto, S.3
Watson, P.H.4
Zhou, X.-P.5
Eng, C.6
-
7
-
-
0034854091
-
Regulation of PTEN transcription by p53
-
Stambolic V, MacPherson D, Sas D, et al. Regulation of PTEN transcription by p53. Mol Cell 2001;8:317-325
-
(2001)
Mol Cell
, vol.8
, pp. 317-325
-
-
Stambolic, V.1
MacPherson, D.2
Sas, D.3
-
8
-
-
31544454967
-
P53 downregulates phosphatase and tensin homologue deleted on chromosome ten (PTEN) protein stability partially through caspase-mediated degradation in cells with proteosome dysfunction
-
Tang Y, Eng C. p53 downregulates phosphatase and tensin homologue deleted on chromosome ten (PTEN) protein stability partially through caspase-mediated degradation in cells with proteosome dysfunction. Cancer Res 2006;66:736-742
-
(2006)
Cancer Res
, vol.66
, pp. 736-742
-
-
Tang, Y.1
Eng, C.2
-
9
-
-
31544454967
-
PTEN autoregulates its expression by stabilization of p53 in a phosphatase-independent manner
-
DOI 10.1158/0008-5472.CAN-05-1557
-
Tang Y, Eng C. PTEN autoregulates its expression by interacting with p53 in a phosphatase-independent manner. Cancer Res 2006;66:736-742 (Pubitemid 43165936)
-
(2006)
Cancer Research
, vol.66
, Issue.2
, pp. 736-742
-
-
Tang, Y.1
Eng, C.2
-
10
-
-
0035200952
-
Allelic losses at 3p and 11p are detected in both epithelial and stromal components of cervical small-cell neuroendocrine carcinoma
-
DOI 10.1097/00022744-200112000-00009
-
Man Y-g, Mannion C, Kuhis E, et al. Allelic loss at 3p and 11p are detected in both epithelial and stromal components of cervical small-cell neuroendocrine carcinoma. Appl Immunohistochem Mol Morphol 2001;9:340-345 (Pubitemid 33098144)
-
(2001)
Applied Immunohistochemistry and Molecular Morphology
, vol.9
, Issue.4
, pp. 340-345
-
-
Man, Y.-G.1
Mannion, C.2
Kuhls, E.3
Moinfar, F.4
Bratthauer, G.L.5
Albores-Saavedra, J.6
Tavassoli, F.A.7
-
11
-
-
36349025868
-
Somatic acquisition of TGFBR1*6A by epithelial and stromal cells during head and neck and colon cancer development
-
DOI 10.1093/hmg/ddm274
-
Bian Y, Knobloch TJ, Sadim M, et al. Somatic acquisition of TGFBR 1*A6 by epithelial and stromal cells during head and neck and colon cancer development. Hum Mol Genet 2007;16:3128-3135 (Pubitemid 350138980)
-
(2007)
Human Molecular Genetics
, vol.16
, Issue.24
, pp. 3128-3135
-
-
Bian, Y.1
Knobloch, T.J.2
Sadim, M.3
Kaklamani, V.4
Raji, A.5
Yang, G.-Y.6
Weghorst, C.M.7
Pasche, B.8
-
12
-
-
0142243215
-
Molecular genetic alterations in the laser-capture-microdissected stroma adjacent to bladder carcinoma
-
Paterson RF, Ulbright TM, MacLennan GT, et al. Molecular genetic alterations in the laser-capture-microdissected stroma adjacent to bladder carcinoma. Cancer 2003;98:1830-1836
-
(2003)
Cancer
, vol.98
, pp. 1830-1836
-
-
Paterson, R.F.1
Ulbright, T.M.2
MacLennan, G.T.3
-
13
-
-
33646249638
-
Epithelial and stromal genetic instability contributes to genesis of colorectal adenomas
-
Ishiguro K, Yoshida T, Yagishita H, Numata Y, Okayasu T. Epithelial and stromal genetic instability contributes to genesis of colorectal adenomas. Gut 2006;55:695-702.
-
(2006)
Gut
, vol.55
, pp. 695-702
-
-
Ishiguro, K.1
Yoshida, T.2
Yagishita, H.3
Numata, Y.4
Okayasu, T.5
-
14
-
-
0024800110
-
A study of an in vitro model for invasion of oral squamous cell carcinoma
-
Matsumoto K, Horikoshi M, Rikimaru K, Enomoto S. A study of an in vitro model for invasion of oral squamous cell carcinoma. J Oral Pathol Med 1989;18:498-501. (Pubitemid 20064432)
-
(1989)
Journal of Oral Pathology and Medicine
, vol.18
, Issue.9
, pp. 498-501
-
-
Matsumoto, K.1
Horikoshi, M.2
Rikimaru, K.3
Enomoto, S.4
-
15
-
-
0043236148
-
Possible alternative carcinogenesis pathway featuring microsatellite instability in colorectal cancer stroma
-
DOI 10.1038/sj.bjc.6601141
-
Matsumoto N, Yoshida T, Yamashita K, Numata Y, Okayasu I. Possible alternative carcinogenesis pathway featuring microsatellite instability in colorectal cancer stroma. Br J Cancer 2003;89:707-712 (Pubitemid 37076178)
-
(2003)
British Journal of Cancer
, vol.89
, Issue.4
, pp. 707-712
-
-
Matsumoto, N.1
Yoshida, T.2
Yamashita, K.3
Numata, Y.4
Okayasu, I.5
-
16
-
-
42149189528
-
Epithelial and stromal genetic instability linked to tumor suppressor genes in ulcerative colitis-associated tumorigenesis
-
Yagishita H, Yoshida T, Ishiguro K, Numata Y, Okayasu I. Epithelial and stromal genetic instability linked to tumor suppressor genes in ulcerative colitis-associated tumorigenesis. Scand J Gastroenterol 2008;43:559-566
-
(2008)
Scand J Gastroenterol
, vol.43
, pp. 559-566
-
-
Yagishita, H.1
Yoshida, T.2
Ishiguro, K.3
Numata, Y.4
Okayasu, I.5
-
17
-
-
33947579196
-
Early genetic instability of both epithelial and stromal cells in esophageal squamous cell carcinomas, contrasted with Barrett's adenocarcinomas
-
DOI 10.1007/s00535-006-1953-4
-
Shiraishi H, Mikami T, Yoshida T, et al. Early genetic instability of both epithelial and stromal cells in esophageal squamous cell carcinoma, contrasted with Barrett's adenocarcinoma. J Gastroenterol 2006;41:1186-1196 (Pubitemid 46487209)
-
(2006)
Journal of Gastroenterology
, vol.41
, Issue.12
, pp. 1186-1196
-
-
Shiraishi, H.1
Mikami, T.2
Yoshida, T.3
Tanabe, S.4
Kobayashi, N.5
Watanabe, M.6
Okayasu, I.7
-
18
-
-
10744226105
-
Genetic alterations in the peritumoral stromal cells of malignant and borderline epithelial ovarian tumors as indicated by allelic imbalance on chromosome 3p
-
DOI 10.1002/ijc.11733
-
Tuhkanen H, Anttila M, Kosma VM, et al. Genetic alterations in the peritumoral stromals cells of malignant and borderline ovarian tumors as indicated by alleleic imbalance of chromosome 3p. Int J Cancer 2004;109:247-252 (Pubitemid 38240927)
-
(2004)
International Journal of Cancer
, vol.109
, Issue.2
, pp. 247-252
-
-
Tuhkanen, H.1
Anttila, M.2
Kosma, V.-M.3
Yla-Herttuala, S.4
Heinonen, S.5
Kuronen, A.6
Juhola, M.7
Tammi, R.8
Tammi, M.9
Mannermaa, A.10
-
19
-
-
33846844836
-
Telomere attrition in isolated high-grade prostatic intraepithelial neoplasia and surrounding stroma is predictive of prostate cancer
-
DOI 10.1593/neo.06745
-
Joshua AM, Vukovic B, Braude I, et al. Telomere attrition in isolated high-grade prostatic intraepithelial neoplasia and surrounding stroma is predictive of prostate cancer. Neoplasia 2007;9:81-89 (Pubitemid 46203936)
-
(2007)
Neoplasia
, vol.9
, Issue.1
, pp. 81-89
-
-
Joshua, A.M.1
Vukovic, B.2
Braude, I.3
Hussein, S.4
Zielenska, M.5
Srigley, J.6
Evans, A.7
Squire, J.A.8
-
20
-
-
57149112529
-
Coevolution of prostate cancer and bone stroma in three-dimensional coculture: Implications for cancer growth and metastasis
-
Sung S-Y, Hsieh C-L, Law A, et al. Coevolution of prostate cancer and bone stroma in three-dimensional coculture: implications for cancer growth and metastasis. Cancer Res 2008;68:9996-10003.
-
(2008)
Cancer Res
, vol.68
, pp. 9996-10003
-
-
Sung, S.-Y.1
Hsieh, C.-L.2
Law, A.3
-
21
-
-
33750631463
-
Mitochondrial microsatellite instability of colorectal cancer stroma
-
DOI 10.1002/ijc.22244
-
Kim HS, LIm HS, Lee SH, et al. Mitochondrial microsatellite instability of colorectal cancer stroma. Int J Cancer 2006;119:2607-2611 (Pubitemid 44691315)
-
(2006)
International Journal of Cancer
, vol.119
, Issue.11
, pp. 2607-2611
-
-
Kim, H.S.1
Lim, H.S.2
Lee, S.H.3
Lee, J.W.4
Nam, S.W.5
Park, W.S.6
Lee, Y.S.7
Lee, J.Y.8
Yoo, N.J.9
-
22
-
-
33845678584
-
Genome-wide loss of heterozygosity and copy number alteration in esophageal squamous cell carcinoma using the Affymetrix genechip mapping 10 K array
-
DOI 10.1186/1471-2164-7-299
-
Hu N, Wang C, Hu Y, et al. Genome-wide loss of heterozygosity and copy number alteration in esophageal squamous cell carcinoma using the Affymetrix GeneChip Mapping 10 K array. BMC Genomics 2006;7:299. (Pubitemid 44941454)
-
(2006)
BMC Genomics
, vol.7
, pp. 299
-
-
Hu, N.1
Wang, C.2
Hu, Y.3
Yang, H.H.4
Kong, L.-H.5
Lu, N.6
Su, H.7
Wang, Q.-H.8
Goldstein, A.M.9
Buetow, K.H.10
Emmert-Buck, M.R.11
Taylor, P.R.12
Lee, M.P.13
-
23
-
-
5644294349
-
Combined total genome loss of heterozygosity scan of breast cancer stroma and epithelium reveals multiplicity of stromal targets
-
DOI 10.1158/0008-5472.CAN-04-2866
-
Fukino K, Shen L, Matsumoto S, Morrison CD, Mutter GL, Eng C. Combined total genome loss-of-heterozygosity scan of breast cancer stroma and epithelium reveals multiplicity of stromal targets. Cancer Res 2004;64:7231-7236 (Pubitemid 39372057)
-
(2004)
Cancer Research
, vol.64
, Issue.20
, pp. 7231-7236
-
-
Fukino, K.1
Shen, L.2
Matsumoto, S.3
Morrison, C.D.4
Mutter, G.L.5
Eng, C.6
-
24
-
-
37349101054
-
Stromal TP53 mutation or 5-locus allelic imbalance and nodal metastases in breast cancer
-
Patocs A, Zhang L, Xu Y, et al. Stromal TP53 mutation or 5-locus allelic imbalance and nodal metastases in breast cancer. N Engl J Med 2007;357:2543-2551
-
(2007)
N Engl J Med
, vol.357
, pp. 2543-2551
-
-
Patocs, A.1
Zhang, L.2
Xu, Y.3
-
25
-
-
28944432805
-
Selective evolution of stromal mesenchyme with p53 loss in response to epithelial tumorigenesis
-
DOI 10.1016/j.cell.2005.09.030, PII S0092867405010366
-
Hill R, Song Y, Cardiff RD, Van Dyke T. Selective evolution of stromal mesenchyme with p53 loss in response to epithelial tumorigenesis. Cell 2005;123:1001-1011 (Pubitemid 41785416)
-
(2005)
Cell
, vol.123
, Issue.6
, pp. 1001-1011
-
-
Hill, R.1
Song, Y.2
Cardiff, R.D.3
Van Dyke, T.4
-
26
-
-
33846144441
-
Microenvironmental genomic alterations and clinicopathological behavior in head and neck squamous cell carcinoma
-
DOI 10.1001/jama.297.2.187
-
Weber F, Xu Y, Zhang L, et al. Microenvironmental genomic alterations correlate with clinico-pathologic behavior in head and neck squamous cell carcinomas. JAMA 2007;297:187-195 (Pubitemid 46089735)
-
(2007)
Journal of the American Medical Association
, vol.297
, Issue.2
, pp. 187-195
-
-
Weber, F.1
Xu, Y.2
Zhang, L.3
Patocs, A.4
Shen, L.5
Platzer, P.6
Eng, C.7
-
27
-
-
33646885230
-
Total-genome analysis of BRCA1/2-related invasive carcinomas of the breast identifies tumor stroma as potential landscaper for neoplastic initiation
-
DOI 10.1086/504090
-
Weber F, Shen L, Fukino K, et al. Total genome analysis of BRC A1/2-related carcinomas of the breast identifies tumor stroma as potential landscaper for neoplastic initiation. Am J Hum Genet 2006;78:961-972 (Pubitemid 43787688)
-
(2006)
American Journal of Human Genetics
, vol.78
, Issue.6
, pp. 961-972
-
-
Weber, F.1
Shen, L.2
Fukino, K.3
Patocs, A.4
Mutter, G.L.5
Caldes, T.6
Eng, C.7
-
28
-
-
58349094961
-
High frequency of TP53 mutation in BRCA1 and sporadic basal-like carcinomas, but not in BRCA1 luminal breast tumors
-
Erratum in: Cancer Res 2009;69:3240
-
Manié E, Vincent-Salomon A, Lehmann-Che J, et al. High frequency of TP53 mutation in BRCA1 and sporadic basal-like carcinomas, but not in BRCA1 luminal breast tumors. Cancer Res 2009;69:663-71. Erratum in: Cancer Res 2009;69:3240.
-
(2009)
Cancer Res
, vol.69
, pp. 663-671
-
-
Manié, E.1
Vincent-Salomon, A.2
Lehmann-Che, J.3
-
29
-
-
0032524069
-
Mutations in the SMAD4/DPC4 gene in juvenile polyposis
-
DOI 10.1126/science.280.5366.1086
-
Howe JR, Roth S, Ringold JC, et al. Mutations in the SMAD4/DPC4 gene in juvenile polyposis. Science 1998;280:1086-1088 (Pubitemid 28234951)
-
(1998)
Science
, vol.280
, Issue.5366
, pp. 1086-1088
-
-
Howe, J.R.1
Roth, S.2
Ringold, J.C.3
Summers, R.W.4
Jarvinen, H.J.5
Sistonen, P.6
Tomlinson, I.P.M.7
Houlston, R.S.8
Bevan, S.9
Mitros, F.A.10
Stone, E.M.11
Aaltonen, L.A.12
-
30
-
-
0034972978
-
Germline mutations of BMPR1 A in juvenile polyposis
-
Howe JR, Blair JA, Sayed MG, et al. Germline mutations of BMPR1 A in juvenile polyposis. Nat Genet 2001;28:184-187
-
(2001)
Nat Genet
, vol.28
, pp. 184-187
-
-
Howe, J.R.1
Blair, J.A.2
Sayed, M.G.3
-
31
-
-
0034967198
-
News and views: To be or not to BMP
-
Eng C. News and views: to be or not to BMP. Nat Genet 2001;28:105-107
-
(2001)
Nat Genet
, vol.28
, pp. 105-107
-
-
Eng, C.1
-
33
-
-
33745578957
-
Smad4 signalling in T cells is required for suppression of gastrointestinal cancer
-
DOI 10.1038/nature04846, PII N04846
-
Kim BG, Li C, Mamura M, et al. Smad4 signalling in T cells is required for suppression of gastrointestinal cancer. Nature 2006;441:1015-1019 (Pubitemid 43980359)
-
(2006)
Nature
, vol.441
, Issue.7096
, pp. 1015-1019
-
-
Kim, B.-G.1
Li, C.2
Qiao, W.3
Mamura, M.4
Kasperczak, B.5
Anver, M.6
Wolfraim, L.7
Hong, S.8
Mushinski, E.9
Potter, M.10
Kim, S.-J.11
Fu, X.-Y.12
Deng, C.13
Letterio, J.J.14
-
34
-
-
36349034540
-
Stromal fibroblasts in colorectal liver metastases originate from resident fibroblasts and generate an inflammatory microenvironment
-
DOI 10.2353/ajpath.2007.060661
-
Mueller L, Goumas FA, Affeldt M, et al. Stromal fibroblasts in colorectal liver metastases originate from resident fibroblasts and generate an inflammatory microenvironment. Am J Pathol 2007;171:1608-1618 (Pubitemid 350158321)
-
(2007)
American Journal of Pathology
, vol.171
, Issue.5
, pp. 1608-1618
-
-
Mueller, L.1
Goumas, F.A.2
Affeldt, M.3
Sandtner, S.4
Gehling, U.M.5
Brilloff, S.6
Walter, J.7
Karnatz, N.8
Lamszus, K.9
Rogiers, X.10
Broering, D.C.11
-
35
-
-
6044270514
-
Role of cancer-associated stromal fibroblasts in metastatic colon cancer to the liver and their expression profiles
-
DOI 10.1038/sj.onc.1208013
-
Nakagawa H, Liyanarachchi S, Davuluri RV, et al. Role of cancer-associated stromal fibroblasts in metastatic colon cancer to the liver and their expression profiles. Oncogene 2004;23:7366-7377 (Pubitemid 39382139)
-
(2004)
Oncogene
, vol.23
, Issue.44
, pp. 7366-7377
-
-
Nakagawa, H.1
Liyanarachchi, S.2
Davuluri, R.V.3
Auer, H.4
Martin Jr., E.W.5
De La Chapelle, A.6
Frankel, W.L.7
-
36
-
-
47049117155
-
P53 mutations in stromal fibroblasts sensitize tumors against chemotherapy
-
DOI 10.1002/ijc.23546
-
Lafkas D, Trimis G, Papavassilou AG, Kiaris H. p53 mutations in stromal fibroblasts sensitize tumors against chemotherapy. Int J Cancer 2008;123:967-971 (Pubitemid 352032428)
-
(2008)
International Journal of Cancer
, vol.123
, Issue.4
, pp. 967-971
-
-
Lafkas, D.1
Trimis, G.2
Papavassiliou, A.G.3
Kiaris, H.4
-
37
-
-
51949094991
-
Role of myofibroblasts in innate chemoresistance of pancreatic carcinoma-epigenetic downregulation of caspases
-
Muerkoster SS, Werbing V, Koch D, et al. Role of myofibroblasts in innate chemoresistance of pancreatic carcinoma-epigenetic downregulation of caspases. Br J Cancer 2008;123:1751-1760
-
(2008)
Br J Cancer
, vol.123
, pp. 1751-1760
-
-
Muerkoster, S.S.1
Werbing, V.2
Koch, D.3
-
38
-
-
42549109044
-
Macro-environment of breast carcinoma: Frequent genetic alterations in the normal appearing skins of patients with breast cancer
-
DOI 10.1038/modpathol.2008.28, PII MODPATHOL200828
-
Moinfar F, Beham A, Friedrich G, et al. Macroenvironment of breast carcinoma: frequent genetic alterations in the normal appearing skins of patients with breast cancer. Mod Pathol 2008;21:639-646 (Pubitemid 351589659)
-
(2008)
Modern Pathology
, vol.21
, Issue.5
, pp. 639-646
-
-
Moinfar, F.1
Beham, A.2
Friedrich, G.3
Deutsch, A.4
Hrzenjak, A.5
Luschin, G.6
Tavassoli, F.A.7
-
39
-
-
57149089521
-
Microenvironmental protection in diffuse large B-cell lymphoma
-
Eng C. Microenvironmental protection in diffuse large B-cell lymphoma. N Engl J Med 2008;359:2379-2381
-
(2008)
N Engl J Med
, vol.359
, pp. 2379-2381
-
-
Eng, C.1
|