Unbiased estimation of odds ratios: Combining genomewide association scans with replication studies

Genetic Epidemiology

Volumn 33, Issue 5, 2009, Pages 406-418

  Bowden, Jack ^a   Dudbridge, Frank ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

Genomewide scans; Selection bias; UMVUE; Winner's curse; WTCCC

Indexed keywords

ARTICLE; BOOTSTRAPPING; CONFIDENCE INTERVAL; CROHN DISEASE; EFFECT SIZE; GENE FREQUENCY; GENE LINKAGE DISEQUILIBRIUM; GENETIC ASSOCIATION; INSULIN DEPENDENT DIABETES MELLITUS; MAXIMUM LIKELIHOOD METHOD; SAMPLE SIZE; SINGLE NUCLEOTIDE POLYMORPHISM; STATISTICAL SIGNIFICANCE; ALGORITHM; ALLELE; BIOLOGICAL MODEL; EPIDEMIOLOGY; GENETIC PREDISPOSITION; HUMAN; HUMAN GENOME; METHODOLOGY; REGRESSION ANALYSIS; REPRODUCIBILITY; RISK; STATISTICAL MODEL; STATISTICS;

ALGORITHMS; ALLELES; EPIDEMIOLOGIC RESEARCH DESIGN; GENE FREQUENCY; GENETIC PREDISPOSITION TO DISEASE; GENOME, HUMAN; GENOME-WIDE ASSOCIATION STUDY; HUMANS; LIKELIHOOD FUNCTIONS; MODELS, GENETIC; MODELS, STATISTICAL; ODDS RATIO; REGRESSION ANALYSIS; REPRODUCIBILITY OF RESULTS; STOCHASTIC PROCESSES;

EID: 70149111937     PISSN: 07410395     EISSN: 10982272     Source Type: Journal    
DOI: 10.1002/gepi.20394     Document Type: Article

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