Selective toxin sequestrants for the treatment of bacterial infections

Journal of the American Chemical Society

Volumn 131, Issue 16, 2009, Pages 5760-5762

  Simpson, Levi S ^a   Burdine, Lyle ^a   Dutta, Amal K ^a   Feranchak, Andrew P ^a   Kodadek, Thomas ^a,b  

^a UNIVERSITY OF TEXAS AT DALLAS   (United States)

^b SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL INFECTIONS; BACTERIAL TOXIN; CELL CULTURE MEDIA; CHOLERA TOXIN; HIGH AFFINITY; HIGH AFFINITY BINDING; INTESTINAL CELLS; SINGLE SEQUENCES; SOLID-PHASE; THERAPEUTIC STRATEGY;

BACTERIOLOGY; CELL CULTURE; CELL MEMBRANES;

TOXIC MATERIALS;

CHOLERA TOXIN; CHOLERA TOXIN B SUBUNIT; QUANTUM DOT; BACTERIAL PROTEIN; LIGAND; PEPTIDE; PEPTIDE LIBRARY; PROTEIN BINDING; PROTEIN SUBUNIT;

ARTICLE; BACTERIAL INFECTION; BINDING AFFINITY; CONTROLLED STUDY; CULTURE MEDIUM; DRUG DESIGN; GEL ELECTROPHORESIS; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; NONHUMAN; TANDEM MASS SPECTROMETRY; WESTERN BLOTTING; BACTERIAL INFECTIONS; CELL LINE; CHEMISTRY; CYTOLOGY; DRUG EFFECTS; ENZYMOLOGY; ESCHERICHIA COLI; HUMAN; INTESTINE MUCOSA; METABOLISM; MICROBIOLOGY; PEPTIDE LIBRARY; PROTEIN SUBUNIT;

BACTERIAL INFECTIONS; BACTERIAL PROTEINS; CELL LINE; CHOLERA TOXIN; ESCHERICHIA COLI; HUMANS; INTESTINAL MUCOSA; LIGANDS; PEPTIDE LIBRARY; PEPTIDES; PROTEIN BINDING; PROTEIN SUBUNITS;

EID: 70149103342     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja900852k     Document Type: Article

References (18)

1. Lopez A. D. Mathers C. D. Ezzati M. Jamison D. T. Murray C. J. Lancet 2006, 367, 1747-57.
2. World Health Organization, "Cholera." January 2009, http://www.who.int/topies/cholera/en/.
3. Schroeder M. S. Am. Fam. Physician 2005, 71, 921-8. Taubes. G. Science 2008, 321, 360.
4. Scheiring J. Andreoli S. P. Zimmerhackl. L. B. Pediatr. Nephrol. 2008, 23, 1749-60.
5. Saha D. Karim M. M. Khan W. A. Ahmed S. Salam M. A. Bennish M. L. N Engl. J. Med 2006, 354, 2452-62.
6. Duncan R. Nat. Rev. Drug Discovery 2003, 2, 347-60.
7. Schaffner F. Gastroenterology 1964, 46, 67-70.
8. Louie T. J. Peppe J. Watt C. K. Johnson D. Mohammed R. Dow G. Weiss. K. Simon. S. John J. F., Jr. Garber. G. Chasan-Taber S. Davidson D. M. Clin. Infect. Dis. 2006, 43, 411-20.
9. Lencer W. I. Delp C. Neutra M. R. Madara. J. L. J. Cell Biol. 1992, 117, 1197-1209.
10. Alluri P. G. Reddy. M. M. Bachhawat-Sikder K. Olivos H. J. Kodadek T. J. Am. Chem. Soc. 2003, 125, 13995-4004.
11. Zuckermann R. N. Martin E. J. Spellmever D. C. Stauber G. B. Shoemaker K. R. Kerr. J. M. Figliozzi G. M Goff D. A. Siani M. A. Simon R. J. J. Med. Chem. 1994, 37, 2678-85.
12. Fowler S. A. Stacy D. M. Blackwell H. E. Org. Lett. 2008, 10, 2329-32.
13. Simon R. J. et al. Proc. Natl. Acad. Sci. U. S. A. 1992, 89, 9367-71.
14. Olivos H. J. Alluri. P. G. Reddv M. M. Salonv D. Kodadek T. Org. Lett. 2002, 4, 4057-4059.
15. Schlenker T. Romac. J. M. Sharara A. I. Roman R. M. Kim S. J. LaRusso N. Liddle R. A. Fitz J. G. Am. J. Physiol. 1997. 273, G1108-17.
16. Mammen M. Choi S. K. Whitesides. G. M. Angew. Chem., Int. Ed. 1998, 37, 2755-2794.
17. Kitov P. I. Sadowska J. M. Mulvey G. Armstrong G. D. Ling H. Pannu N. S. Read. R. J. Bundle D. R. Nature {London) 2000, 403, 669-72.
18. Merritt E. A. Zhang Z. Pickens J. C. Ahn M. Hol. W. G. Fan E. J. Am. Chem. Soc. 2002, 124, 8818-24.