Design and development of enzymatically activatable photosensitizer based on unique characteristics of thiazole orange

Journal of the American Chemical Society

Volumn 131, Issue 17, 2009, Pages 6058-6059

  Koide, Yuichiro ^a,b   Urano, Yasuteru ^a,b   Yatsushige, Akira ^a,b   Hanaoka, Kenjiro ^a,b   Terai, Takuya ^a,b   Nagano, Tetsuo ^a,b  

^a UNIVERSITY OF TOKYO   (Japan)

^b JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

DESIGN AND DEVELOPMENT; GALACTOSIDASES; HEK-293; LIGHT ILLUMINATION; NOVEL DESIGN; REPORTER ENZYMES; SIDE EFFECT;

CELL MEMBRANES; COMPLEXATION; FLUORESCENCE;

PHOTOSENSITIZERS;

4 [5 (4 METHYL 1 PIPERAZINYL)[2,5' BI 1H BENZIMIDAZOL] 2' YL]PHENOL; 4',6 DIAMIDINO 2 PHENYLINDOLE; BENZOTHIAZOLE; BETA GALACTOSIDASE; CELL SURFACE PROTEIN; DOUBLE STRANDED DNA; DOUBLE STRANDED RNA; FLUORESCENT DYE; PHOTOSENSITIZING AGENT; QUINOLINE; THIAZOLE ORANGE; BENZOTHIAZOLE DERIVATIVE; DNA; QUINOLINE DERIVATIVE;

ARTICLE; CELL DEATH; CELL NUCLEUS MEMBRANE; CELL STRAIN HEK293; CELL SURFACE; CELLULAR DISTRIBUTION; CHEMICAL REACTION; CHEMICAL STRUCTURE; DNA BINDING; ENZYME ACTIVATION; FLOW CYTOMETRY; FLUORESCENCE MICROSCOPY; GENE DIRECTED ENZYME PRODRUG THERAPY; HELA CELL; HUMAN; HYDROPHILICITY; PROTEIN HYDROLYSIS; RADIOSENSITIVITY; CHEMISTRY; FLUORESCENCE; HYDROLYSIS; METABOLISM; PARTICLE SIZE; REPRODUCIBILITY; SURFACE PROPERTY; SYNTHESIS;

BENZOTHIAZOLES; BETA-GALACTOSIDASE; DNA; FLUORESCENCE; HELA CELLS; HUMANS; HYDROLYSIS; MOLECULAR STRUCTURE; PARTICLE SIZE; PHOTOSENSITIZING AGENTS; QUINOLINES; REPRODUCIBILITY OF RESULTS; SURFACE PROPERTIES;

EID: 70149091735     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja900443b     Document Type: Article

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