A panel of high resolution melting (HRM) technology-based assays with direct sequencing possibility for effective mutation screening of EGFR and K-ras genes

Cellular Oncology

Volumn 31, Issue 5, 2009, Pages 329-333

  Heideman, D A M ^a   Thunnissen, F B ^a   Doeleman, M ^a   Kramer, D ^a,b   Verheul, H M ^a   Smit, E F ^a   Postmus, P E ^a   Meijer, C J L M ^a   Meijer, G A ^a   Snijders, P J F ^a  

^a VU UNIVERSITY MEDICAL CENTER   (Netherlands)

^b UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

Author keywords

(nested ) PCR; Anti EGFR monoclonal antibodies; Codon; Direct cycle sequencing; EGFR targeted therapies; Epidermal growth factor receptor; Formalin fixed paraffin embedded; Genotype; HRM; K ras; Molecular diagnostics; Personalized therapy; Receptor tyrosine kinase inhibitors; TKI

Indexed keywords

EPIDERMAL GROWTH FACTOR RECEPTOR; K RAS PROTEIN;

ARTICLE; CONTROLLED STUDY; GENE MUTATION; GENE SEQUENCE; HIGH RESOLUTION MELTING TECHNOLOGY BASED ASSAY; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; SCREENING;

BASE SEQUENCE; EXONS; GENES, RAS; GENOME, HUMAN; GENOTYPE; HUMANS; MUTATION; NEOPLASMS; NUCLEIC ACID DENATURATION; PROTO-ONCOGENE PROTEINS P21(RAS); RECEPTOR, EPIDERMAL GROWTH FACTOR; SEQUENCE ANALYSIS, DNA;

EID: 70149091283     PISSN: 15705870     EISSN: None     Source Type: Journal    
DOI: 10.1155/2009/465850     Document Type: Article

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