Lipopolysaccharide evokes resistance to erythropoiesis induced by the long-acting erythropoietin analogue darbepoetin alfa in rats

Anesthesia and Analgesia

Volumn 109, Issue 3, 2009, Pages 705-711

  Brendt, Peter ^a   Horwat, Ariane ^a   Schäfer, Simon T ^a   Dreyer, Sven C ^a   Göthert, Joachim ^a   Peters, Jürgen ^a  

^a UNIVERSITY HOSPITAL ESSEN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

HEMOGLOBIN; IRON; LIPOPOLYSACCHARIDE; NOVEL ERYTHROPOIESIS STIMULATING PROTEIN; ANTIANEMIC AGENT; DRUG DERIVATIVE; ERYTHROPOIETIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLOOD; CONTROLLED STUDY; ERYTHROCYTE COUNT; ERYTHROPOIESIS; ESCHERICHIA COLI; IRON METABOLISM; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; RETICULOCYTE; RETICULOCYTE COUNT; ANEMIA; ANIMAL; ERYTHROCYTE; INTENSIVE CARE UNIT; LEWIS RAT; METABOLISM; TIME;

ANEMIA; ANIMALS; ERYTHROCYTES; ERYTHROPOIESIS; ERYTHROPOIETIN; ESCHERICHIA COLI; HEMATINICS; INTENSIVE CARE UNITS; LIPOPOLYSACCHARIDES; MALE; RATS; RATS, INBRED LEW; RETICULOCYTES; TIME FACTORS;

EID: 70149083324     PISSN: 00032999     EISSN: None     Source Type: Journal    
DOI: 10.1213/ane.0b013e3181adc80f     Document Type: Article

References (34)

1. Corwin HL, Gettinger A, Pearl RG, Fink MP, Levy MM, Abraham E, MacIntyre NR, Shabot MM, Duh MS, Shapiro MJ. The CRIT Study: anemia and blood transfusion in the critically ill-current clinical practice in the United States. Crit Care Med 2004;32:39-52 (Pubitemid 38125561)
2. Smoller BR, Kruskall MS. Phlebotomy for diagnostic laboratory tests in adults. Pattern of use and effect on transfusion requirements. N Engl J Med 1986;314:1233-5 (Pubitemid 16106410)
3. Hebert PC, Wells G, Tweeddale M, Martin C, Marshall J, Pham B, Blajchman M, Schweitzer I, Pagliarello G. Does transfusion practice affect mortality in critically ill patients? Transfusion Requirements in Critical Care (TRICC) Investigators and the Can Critical Care Trials Group. Am J Respir Crit Care Med 1997;155:1618-23
4. Nguyen BV, Bota DP, Melot C, Vincent JL. Time course of hemoglobin concentrations in nonbleeding intensive care unit patients. Crit Care Med 2003;31:406-10 (Pubitemid 36232933)
5. Orkin SH, Weiss MJ. Apoptosis. Cutting red-cell production. Nature 1999;401:433, 435-6
6. Silva M, Benito A, Sanz C, Prosper F, Ekhterae D, Nunez G, Fernandez-Luna JL. Erythropoietin can induce the expression of Bcl-x(L) through Stat5 in erythropoietin-dependent progenitor cell lines. J Biol Chem 1999;274:22165-9
7. Socolovsky M, Constantinescu SN, Bergelson S, Sirotkin A, Lodish HF. Cytokines in hematopoiesis: specificity and redundancy in receptor function. Adv Protein Chem 1998; 52:141-98 (Pubitemid 28489188)
8. Wojchowski DM, Gregory RC, Miller CP, Pandit AK, Pircher TJ. Signal transduction in the erythropoietin receptor system. Exp Cell Res 1999;253:143-56
9. Joy MS. Darbepoetin alfa: a novel erythropoiesis-stimulating protein. Ann Pharmacother 2002;36:1183-92 (Pubitemid 34755797)
10. Elliott S, Lorenzini T, Asher S, Aoki K, Brankow D, Buck L, Busse L, Chang D, Fuller J, Grant J, Hernday N, Hokum M, Hu S, Knudten A, Levin N, Komorowski R, Martin F, Navarro R, Osslund T, Rogers G, Rogers N, Trail G, Egrie J. Enhancement of therapeutic protein in vivo activities through glycoengineering. Nat Biotechnol 2003;21:414-21 (Pubitemid 36397662)
11. Frede S, Fandrey J, Pagel H, Hellwig T, Jelkmann W. Erythropoietin gene expression is suppressed after lipopolysaccharide or interleukin-1 beta injections in rats. Am J Physiol 1997;273: R1067-71
12. Krafte-Jacobs B, Bock GH. Circulating erythropoietin and interleukin-6 concentrations increase in critically ill children with sepsis and septic shock. Crit Care Med 1996;24:1455-9 (Pubitemid 26313744)
13. Abel J, Spannbrucker N, Fandrey J, Jelkmann W. Serum erythropoietin levels in patients with sepsis and septic shock. Eur J Haematol 1996;57:359-63 (Pubitemid 27008287)
14. Tamion F, Le Cam-Duchez V, Menard JF, Girault C, Coquerel A, Bonmarchand G. Erythropoietin and renin as biological markers in critically ill patients. Crit Care 2004;8:R328-R335
15. R'Zik S, Beguin Y. Serum soluble transferrin receptor concentration is an accurate estimate of the mass of tissue receptors. Exp Hematol 2001;29:677-85 (Pubitemid 32500368)
16. Tiao G, Rafferty J, Ogle C, Fischer JE, Hasselgren PO. Detrimental effect of nitric oxide synthase inhibition during endotoxemia may be caused by high levels of tumor necrosis factor and interleukin-6. Surgery 1994;116:332-7; discussion 337-8
17. Deitch EA. Animal models of sepsis and shock: a review and lessons learned. Shock 1998;9:1-11 (Pubitemid 128463868)
18. Laterre PF, Levy H, Clermont G, Ball DE, Garg R, Nelson DR, Dhainaut JF, Angus DC. Hospital mortality and resource use in subgroups of the Recombinant Human Activated Protein C Worldwide Evaluation in Severe Sepsis (PROWESS) trial. Crit Care Med 2004;32:2207-18 (Pubitemid 39491799)
19. Poschl JM, Leray C, Ruef P, Cazenave JP, Linderkamp O. Endotoxin binding to erythrocyte membrane and erythrocyte deformability in human sepsis and in vitro. Crit Care Med 2003;31:924-8 (Pubitemid 36379605)
20. Weiss G, Goodnough LT. Anemia of chronic disease. N Engl J Med 2005;352:1011-23
21. Kemna E, Pickkers P, Nemeth E, van der Hoeven H, Swinkels D. Time-course analysis of hepcidin, serum iron, and plasma cytokine levels in humans injected with LPS. Blood 2005; 106:1864-6 (Pubitemid 41208606)
22. Garcia PC, Longhi F, Branco RG, Piva JP, Lacks D, Tasker RC. Ferritin levels in children with severe sepsis and septic shock. Acta Paediatr 2007;96:1829-31 (Pubitemid 350132044)
23. Kong WN, Chang YZ, Wang SM, Zhai XL, Shang JX, Li LX, Duan XL. Effect of erythropoietin on hepcidin, DMT1 with IRE, and hephaestin gene expression in duodenum of rats. J Gastroenterol 2008;43:136-43
24. Skikne BS, Cook JD. Effect of enhanced erythropoiesis on iron absorption. J Lab Clin Med 1992;120:746-51
25. Means RT Jr, Krantz SB. Progress in understanding the pathogenesis of the anemia of chronic disease. Blood 1992;80:1639-47
26. Gabriel A, Kozek S, Chiari A, Fitzgerald R, Grabner C, Geissler K, Zimpfer M, Stockenhuber F, Bircher NG. High-dose recombinant human erythropoietin stimulates reticulocyte production in patients with multiple organ dysfunction syndrome. J Trauma 1998;44:361-7 (Pubitemid 28124179)
27. van Iperen CE, Gaillard CA, Kraaijenhagen RJ, Braam BG, Marx JJ, van de Wiel A. Response of erythropoiesis and iron metabolism to recombinant human erythropoietin in intensive care unit patients. Crit Care Med 2000;28:2773-8
28. Silver M, Corwin MJ, Bazan A, Gettinger A, Enny C, Corwin HL. Efficacy of recombinant human erythropoietin in critically ill patients admitted to a long-term acute care facility: a randomized, double-blind, placebo-controlled trial. Crit Care Med 2006;34:2310-6 (Pubitemid 44260014)
29. Corwin HL, Gettinger A, Pearl RG, Fink MP, Levy MM, Shapiro MJ, Corwin MJ, Colton T. Efficacy of recombinant human erythropoietin in critically ill patients: a randomized controlled trial. JAMA 2002;288:2827-35 (Pubitemid 35425068)
30. Papadaki HA, Kritikos HD, Valatas V, Boumpas DT, Eliopoulos GD. Anemia of chronic disease in rheumatoid arthritis is associated with increased apoptosis of bone marrow erythroid cells: improvement following anti-tumor necrosis factor-alpha antibody therapy. Blood 2002;100:474-82 (Pubitemid 34761109)
31. Coccia MA, Cooke K, Stoney G, Pistillo J, Del Castillo J, Duryea D, Tarpley JE, Molineux G. Novel erythropoiesis stimulating protein (darbepoetin alfa) alleviates anemia associated with chronic inflammatory disease in a rodent model. Exp Hematol 2001;29:1201-9 (Pubitemid 32927221)
32. Silva AT, Cohen J. Role of interferon-gamma in experimental gram-negative sepsis. J Infect Dis 1992;166:331-5
33. Taniguchi S, Dai CH, Price JO, Krantz SB. Interferon gamma downregulates stem cell factor and erythropoietin receptors but not insulin-like growth factor-I receptors in human erythroid colony-forming cells. Blood 1997;90:2244-52 (Pubitemid 27392708)
34. Maratheftis CI, Andreakos E, Moutsopoulos HM, Voulgarelis M. Toll-like receptor-4 is up-regulated in hematopoietic progenitor cells and contributes to increased apoptosis in myelodysplastic syndromes. Clin Cancer Res 2007;13:1154-60 (Pubitemid 46424055)