Structure based virtual screening of GSK-3β: Importance of protein flexibility and induced fit

Bioorganic and Medicinal Chemistry Letters

Volumn 19, Issue 19, 2009, Pages 5582-5585

  Mishra, Nibha ^a   Basu, Arijit ^a   Jayaprakash, Venkatesan ^a   Sharon, Ashoke ^a   Basu, Mahua ^b   Patnaik, Kiran K ^a  

^a BIRLA INSTITUTE OF TECHNOLOGY   (India)

^b Shri Shikshayatan College   (India)

Author keywords

Docking; GSK 3 ; Induced fit; Virtual screening

Indexed keywords

DOCKING PROTEIN; GLYCOGEN SYNTHASE KINASE 3;

ARTICLE; CORRELATION ANALYSIS; IC 50; PROTEIN ANALYSIS; PROTEIN STRUCTURE; VIRTUAL REALITY;

CATALYTIC DOMAIN; COMPUTER SIMULATION; DRUG DESIGN; GLYCOGEN SYNTHASE KINASE 3; PROTEIN STRUCTURE, TERTIARY;

EID: 70049111237     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2009.08.042     Document Type: Article

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