메뉴 건너뛰기




Volumn 1294, Issue , 2009, Pages 22-28

NT69L, a novel analgesic, shows synergy with morphine

Author keywords

Antinociception; Hot plate; Morphine; Neurotensin; Rat; Synergism

Indexed keywords

LEVOCABASTINE; M 8777; MORPHINE SULFATE; NEUROTENSIN; NEUROTENSIN 69L; UNCLASSIFIED DRUG;

EID: 70049106921     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.brainres.2009.07.086     Document Type: Article
Times cited : (30)

References (50)
  • 2
    • 0032859516 scopus 로고    scopus 로고
    • Comparison of ketamine-induced thought disorder in healthy volunteers and thought disorder in schizophrenia
    • Adler C.M., Malhotra A.K., Elman I., Goldberg T., Egan M., Pickar D., and Breier A. Comparison of ketamine-induced thought disorder in healthy volunteers and thought disorder in schizophrenia. Am. J. Psychiatry 156 (1999) 1646-1649
    • (1999) Am. J. Psychiatry , vol.156 , pp. 1646-1649
    • Adler, C.M.1    Malhotra, A.K.2    Elman, I.3    Goldberg, T.4    Egan, M.5    Pickar, D.6    Breier, A.7
  • 3
    • 0017177903 scopus 로고
    • Hypothermia and intolerance to cold induced by intracisternal administration of the hypothalamic peptide neurotensin
    • Bissette G., Nemeroff C.B., Loosen P.T., Prange A.J., and Lipton M.A. Hypothermia and intolerance to cold induced by intracisternal administration of the hypothalamic peptide neurotensin. Nature 262 (1976) 607-609
    • (1976) Nature , vol.262 , pp. 607-609
    • Bissette, G.1    Nemeroff, C.B.2    Loosen, P.T.3    Prange, A.J.4    Lipton, M.A.5
  • 4
    • 0036828221 scopus 로고    scopus 로고
    • Synergy between mu opioid ligands: evidence for functional interactions among mu opioid receptor subtypes
    • Bolan E.A., Tallarida R.J., and Pasternak G.W. Synergy between mu opioid ligands: evidence for functional interactions among mu opioid receptor subtypes. J. Pharmacol. Exp. Ther. 303 (2002) 557-562
    • (2002) J. Pharmacol. Exp. Ther. , vol.303 , pp. 557-562
    • Bolan, E.A.1    Tallarida, R.J.2    Pasternak, G.W.3
  • 5
    • 70049102141 scopus 로고    scopus 로고
    • Boules, M., Richelson, E., NTS1 neurotensin receptor. In: S.J. Enna and D.B. Bylund (Eds.), xPharm, Elsevier, Inc. http://www.xpharm.com/citation?Article_ID = 146, New York City, 2004a.
    • Boules, M., Richelson, E., NTS1 neurotensin receptor. In: S.J. Enna and D.B. Bylund (Eds.), xPharm, Elsevier, Inc. http://www.xpharm.com/citation?Article_ID = 146, New York City, 2004a.
  • 6
    • 70049094775 scopus 로고    scopus 로고
    • Boules, M., Richelson, E., NTS2 neurotensin receptor. In: S.J. Enna and D.B. Bylund (Eds.), xPharm, Elsevier, Inc. http://www.xpharm.com/citation?Article_ID = 147, New York City, 2004b.
    • Boules, M., Richelson, E., NTS2 neurotensin receptor. In: S.J. Enna and D.B. Bylund (Eds.), xPharm, Elsevier, Inc. http://www.xpharm.com/citation?Article_ID = 147, New York City, 2004b.
  • 7
    • 70049104698 scopus 로고    scopus 로고
    • Boules, M., Richelson, E., NTS3 neurotensin receptor. In: S.J. Enna and D.B. Bylund (Eds.), xPharm, Elsevier, Inc http://www.xpharm.com/citation?Article_ID = 42295, New York City, 2004c.
    • Boules, M., Richelson, E., NTS3 neurotensin receptor. In: S.J. Enna and D.B. Bylund (Eds.), xPharm, Elsevier, Inc http://www.xpharm.com/citation?Article_ID = 42295, New York City, 2004c.
  • 8
  • 9
    • 33750982434 scopus 로고    scopus 로고
    • Interactions between NTS2 neurotensin and opioid receptors on two nociceptive responses assessed on the hot plate test in mice
    • Bredeloux P., Costentin J., and Dubuc I. Interactions between NTS2 neurotensin and opioid receptors on two nociceptive responses assessed on the hot plate test in mice. Behav. Brain Res. 175 (2006) 399-407
    • (2006) Behav. Brain Res. , vol.175 , pp. 399-407
    • Bredeloux, P.1    Costentin, J.2    Dubuc, I.3
  • 10
    • 0015821329 scopus 로고
    • The isolation of a new hypotensive peptide, neurotensin, from bovine hypothalami
    • Carraway R., and Leeman S.E. The isolation of a new hypotensive peptide, neurotensin, from bovine hypothalami. J. Biol. Chem. 248 (1973) 6854-6861
    • (1973) J. Biol. Chem. , vol.248 , pp. 6854-6861
    • Carraway, R.1    Leeman, S.E.2
  • 12
    • 0032911441 scopus 로고    scopus 로고
    • Characterization of high affinity neurotensin receptor NTR1 in HL-60 cells and its down regulation during granulocytic differentiation
    • Choi S.Y., Chae H.D., Park T.J., Ha H., and Kim K.T. Characterization of high affinity neurotensin receptor NTR1 in HL-60 cells and its down regulation during granulocytic differentiation. Br. J. Pharmacol. 126 (1999) 1050-1056
    • (1999) Br. J. Pharmacol. , vol.126 , pp. 1050-1056
    • Choi, S.Y.1    Chae, H.D.2    Park, T.J.3    Ha, H.4    Kim, K.T.5
  • 13
    • 0017776306 scopus 로고
    • Neurotensin administered intracisternally inhibits responsiveness of mice to noxious stimuli
    • Clineschmidt B.V., and McGuffin J.C. Neurotensin administered intracisternally inhibits responsiveness of mice to noxious stimuli. Eur. J. Pharmacol. 46 (1977) 395-396
    • (1977) Eur. J. Pharmacol. , vol.46 , pp. 395-396
    • Clineschmidt, B.V.1    McGuffin, J.C.2
  • 15
    • 0020333724 scopus 로고
    • Antinocisponsive effects of neurotensin and neurotensin-related peptides
    • Clineschmidt B.V., Martin G.E., and Veber D.F. Antinocisponsive effects of neurotensin and neurotensin-related peptides. Ann. N. Y. Acad. Sci. 400 (1982) 283-306
    • (1982) Ann. N. Y. Acad. Sci. , vol.400 , pp. 283-306
    • Clineschmidt, B.V.1    Martin, G.E.2    Veber, D.F.3
  • 16
    • 0032879770 scopus 로고    scopus 로고
    • The partial agonist properties of levocabastine in neurotensin-induced analgesia
    • Dubuc I., Remande S., and Costentin J. The partial agonist properties of levocabastine in neurotensin-induced analgesia. Eur. J. Pharmacol. 381 (1999) 9-12
    • (1999) Eur. J. Pharmacol. , vol.381 , pp. 9-12
    • Dubuc, I.1    Remande, S.2    Costentin, J.3
  • 18
    • 0032509391 scopus 로고    scopus 로고
    • Synthesis of (2S)-2-amino-3-(1H-4-indolyl) propanoic acid, a novel trryptophan analog for structural modification of bioactive peptides
    • Fauq A.H., Hong F., Cusack B., Tyler B.M., Pang Y.P., and Richelson E. Synthesis of (2S)-2-amino-3-(1H-4-indolyl) propanoic acid, a novel trryptophan analog for structural modification of bioactive peptides. Tetrahedron: Asymmetry 9 (1998) 4127-4134
    • (1998) Tetrahedron: Asymmetry , vol.9 , pp. 4127-4134
    • Fauq, A.H.1    Hong, F.2    Cusack, B.3    Tyler, B.M.4    Pang, Y.P.5    Richelson, E.6
  • 19
    • 0029563665 scopus 로고
    • Isobolographic analysis of interactions: an update on applications and utility
    • Gessner P.K. Isobolographic analysis of interactions: an update on applications and utility. Toxicology 105 (1995) 161-179
    • (1995) Toxicology , vol.105 , pp. 161-179
    • Gessner, P.K.1
  • 20
    • 0017071829 scopus 로고
    • Effects of morphine on central catecholamine turnover, blood pressure and heart rate in the rat
    • Gomes C., Svensson T.H., and Trolin G. Effects of morphine on central catecholamine turnover, blood pressure and heart rate in the rat. Naunyn Schmiedebergs Arch. Pharmacol. 294 (1976) 141-147
    • (1976) Naunyn Schmiedebergs Arch. Pharmacol. , vol.294 , pp. 141-147
    • Gomes, C.1    Svensson, T.H.2    Trolin, G.3
  • 21
    • 0031826026 scopus 로고    scopus 로고
    • Mechanisms of regulation of neurotensin receptors
    • Hermans E., and Maloteaux J.M. Mechanisms of regulation of neurotensin receptors. Pharmacol. Ther. 79 (1998) 89-104
    • (1998) Pharmacol. Ther. , vol.79 , pp. 89-104
    • Hermans, E.1    Maloteaux, J.M.2
  • 25
    • 0030603088 scopus 로고    scopus 로고
    • Inhibition of morphine tolerance by NMDA receptor antagonists in the formalin test
    • Lutfy K., Shen K.Z., Woodward R.M., and Weber E. Inhibition of morphine tolerance by NMDA receptor antagonists in the formalin test. Brain Res. 731 (1996) 171-181
    • (1996) Brain Res. , vol.731 , pp. 171-181
    • Lutfy, K.1    Shen, K.Z.2    Woodward, R.M.3    Weber, E.4
  • 28
    • 0023877328 scopus 로고
    • Solubilization and characterization of active neurotensin receptors from mouse brain
    • Mazella J., Chabry J., Kitabgi P., and Vincent J.P. Solubilization and characterization of active neurotensin receptors from mouse brain. J. Biol. Chem. 263 (1988) 144-149
    • (1988) J. Biol. Chem. , vol.263 , pp. 144-149
    • Mazella, J.1    Chabry, J.2    Kitabgi, P.3    Vincent, J.P.4
  • 29
    • 0029811945 scopus 로고    scopus 로고
    • Structure, functional expression, and cerebral localization of the levocabastine-sensitive neurotensin/neuromedin N receptor from mouse brain
    • Mazella J., Botto J.M., Guillemare E., Coppola T., Sarret P., and Vincent J.P. Structure, functional expression, and cerebral localization of the levocabastine-sensitive neurotensin/neuromedin N receptor from mouse brain. J. Neurosci. 16 (1996) 5613-5620
    • (1996) J. Neurosci. , vol.16 , pp. 5613-5620
    • Mazella, J.1    Botto, J.M.2    Guillemare, E.3    Coppola, T.4    Sarret, P.5    Vincent, J.P.6
  • 30
    • 0347318197 scopus 로고    scopus 로고
    • Acute effects of ketamine on memory systems and psychotic symptoms in healthy volunteers
    • Morgan C.J., Mofeez A., Brandner B., Bromley L., and Curran H.V. Acute effects of ketamine on memory systems and psychotic symptoms in healthy volunteers. Neuropsychopharmacology 29 (2004) 208-218
    • (2004) Neuropsychopharmacology , vol.29 , pp. 208-218
    • Morgan, C.J.1    Mofeez, A.2    Brandner, B.3    Bromley, L.4    Curran, H.V.5
  • 31
    • 0018668629 scopus 로고
    • Alterations in nociception and body temperature after intracisternal administration of neurotensin, beta-endorphin, other endogenous peptides, and morphine
    • Nemeroff C.B., Osbahr A.J., Manberg P.J., Ervin G.N., and Prange A.J. Alterations in nociception and body temperature after intracisternal administration of neurotensin, beta-endorphin, other endogenous peptides, and morphine. Proc. Natl. Acad. Sci. U. S. A. 76 (1979) 5368-5371
    • (1979) Proc. Natl. Acad. Sci. U. S. A. , vol.76 , pp. 5368-5371
    • Nemeroff, C.B.1    Osbahr, A.J.2    Manberg, P.J.3    Ervin, G.N.4    Prange, A.J.5
  • 32
    • 0034600274 scopus 로고    scopus 로고
    • Interaction between intrathecal morphine and glutamate receptor antagonists in formalin test
    • Nishiyama T. Interaction between intrathecal morphine and glutamate receptor antagonists in formalin test. Eur. J. Pharmacol. 395 (2000) 203-210
    • (2000) Eur. J. Pharmacol. , vol.395 , pp. 203-210
    • Nishiyama, T.1
  • 34
    • 0022006480 scopus 로고
    • Analgesic effects of antihistaminics
    • Rumore M.M., and Schlichting D.A. Analgesic effects of antihistaminics. Life Sci. 36 (1985) 403-416
    • (1985) Life Sci. , vol.36 , pp. 403-416
    • Rumore, M.M.1    Schlichting, D.A.2
  • 36
    • 0038689224 scopus 로고    scopus 로고
    • Immunohistochemical distribution of NTS2 neurotensin receptors in the rat central nervous system
    • Sarret P., Perron A., Stroh T., and Beaudet A. Immunohistochemical distribution of NTS2 neurotensin receptors in the rat central nervous system. J. Comp. Neurol. 461 (2003) 520-538
    • (2003) J. Comp. Neurol. , vol.461 , pp. 520-538
    • Sarret, P.1    Perron, A.2    Stroh, T.3    Beaudet, A.4
  • 37
    • 24744449309 scopus 로고    scopus 로고
    • Potent spinal analgesia elicited through stimulation of NTS2 neurotensin receptors
    • Sarret P., Esdaile M.J., Perron A., Martinez J., Stroh T., and Beaudet A. Potent spinal analgesia elicited through stimulation of NTS2 neurotensin receptors. J. Neurosci. 25 (2005) 8188-8196
    • (2005) J. Neurosci. , vol.25 , pp. 8188-8196
    • Sarret, P.1    Esdaile, M.J.2    Perron, A.3    Martinez, J.4    Stroh, T.5    Beaudet, A.6
  • 38
    • 0024451893 scopus 로고
    • Further characterization of neurotensin binding in the rat brain: levocabastine-displaceable neurotensin binding sites are not histamine-H1 receptors
    • Schotte A., and Leysen J.E. Further characterization of neurotensin binding in the rat brain: levocabastine-displaceable neurotensin binding sites are not histamine-H1 receptors. Biochem. Pharmacol. 38 (1989) 3891-3893
    • (1989) Biochem. Pharmacol. , vol.38 , pp. 3891-3893
    • Schotte, A.1    Leysen, J.E.2
  • 39
    • 0031558635 scopus 로고    scopus 로고
    • Opioid-induced release of neurotensin in the periaqueductal gray matter of freely moving rats
    • Stiller C.O., Gustafsson H., Fried K., and Brodin E. Opioid-induced release of neurotensin in the periaqueductal gray matter of freely moving rats. Brain Res. 774 (1997) 149-158
    • (1997) Brain Res. , vol.774 , pp. 149-158
    • Stiller, C.O.1    Gustafsson, H.2    Fried, K.3    Brodin, E.4
  • 40
    • 0025345759 scopus 로고
    • Structure and functional expression of the cloned rat neurotensin receptor
    • Tanaka K., Masu M., and Nakanishi S. Structure and functional expression of the cloned rat neurotensin receptor. Neuron 4 (1990) 847-854
    • (1990) Neuron , vol.4 , pp. 847-854
    • Tanaka, K.1    Masu, M.2    Nakanishi, S.3
  • 41
    • 0034685954 scopus 로고    scopus 로고
    • Antinociception produced by mu opioid receptor activation in the amygdala is partly dependent on activation of mu opioid and neurotensin receptors in the ventral periaqueductal gray
    • Tershner S.A., and Helmstetter F.J. Antinociception produced by mu opioid receptor activation in the amygdala is partly dependent on activation of mu opioid and neurotensin receptors in the ventral periaqueductal gray. Brain Res. 865 (2000) 17-26
    • (2000) Brain Res. , vol.865 , pp. 17-26
    • Tershner, S.A.1    Helmstetter, F.J.2
  • 42
    • 0032507690 scopus 로고    scopus 로고
    • Evidence for additional neurotensin receptor subtypes: neurotensin analogs that distinguish between neurotensin-mediated hypothermia and antinociception
    • Tyler B.M., Cusack B., Douglas C.L., Souder T., and Richelson E. Evidence for additional neurotensin receptor subtypes: neurotensin analogs that distinguish between neurotensin-mediated hypothermia and antinociception. Brain Res. 792 (1998) 246-252
    • (1998) Brain Res. , vol.792 , pp. 246-252
    • Tyler, B.M.1    Cusack, B.2    Douglas, C.L.3    Souder, T.4    Richelson, E.5
  • 43
    • 0032536747 scopus 로고    scopus 로고
    • In vivo studies with low doses of levocabastine and diphenhydramine, but not pyrilamine, antagonize neurotensin-mediated antinociception
    • Tyler B.M., Groshan K., Cusack B., and Richelson E. In vivo studies with low doses of levocabastine and diphenhydramine, but not pyrilamine, antagonize neurotensin-mediated antinociception. Brain Res. 787 (1998) 78-84
    • (1998) Brain Res. , vol.787 , pp. 78-84
    • Tyler, B.M.1    Groshan, K.2    Cusack, B.3    Richelson, E.4
  • 46
    • 0029585157 scopus 로고
    • Neurotensin receptors: binding properties, transduction pathways, and structure
    • Vincent J.P. Neurotensin receptors: binding properties, transduction pathways, and structure. Cell. Mol. Neurobiol. 15 (1995) 501-512
    • (1995) Cell. Mol. Neurobiol. , vol.15 , pp. 501-512
    • Vincent, J.P.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.