Low viscosity poly(trimethylene carbonate) for localized drug delivery: Rheological properties and in vivo degradation

Macromolecular Bioscience

Volumn 9, Issue 8, 2009, Pages 786-794

  Timbart, Laurianne ^a   Tse, M Yat ^a   Pang, Stephen C ^a   Babasola, Oladunni ^a   Amsden, Brian G ^a  

^a QUEEN S UNIVERSITY   (Canada)

Author keywords

Biocompatibility; Biodegradable; Biomaterials; Drug delivery systems; Polycarbonates

Indexed keywords

ACTIVATED MACROPHAGES; BIODEGRADABLE; DRUG DELIVERY SYSTEMS; GLASS TRANSITION TEMPERATURE; IMPLANT SURFACE; IN-VIVO; INITIAL MOLECULAR WEIGHT; LOCALIZED DELIVERY; LOW MOLECULAR WEIGHT; LOW VISCOSITY; MOLECULAR CHAINS; OCTAN-1-OL; POLY(TRIMETHYLENE CARBONATE); POLYMER MASS; REACTIVE SPECIES; RHEOLOGICAL PROPERTY;

ASTROPHYSICS; BIOCOMPATIBILITY; BIOLOGICAL MATERIALS; CARBONATES; CARBONATION; DEGRADATION; DISSOLUTION; DRUG DELIVERY; ENZYMATIC HYDROLYSIS; GLASS TRANSITION; POLYCARBONATES; POLYMERS; RHEOLOGY; RING OPENING POLYMERIZATION; TIN; VISCOSITY; WEIGHING;

MOLECULAR WEIGHT;

2 ETHYLHEXANOIC ACID; BIOMATERIAL; DRUG CARRIER; OCTAN 1 OL; OCTANE; POLY(TRIMETHYLENE CARBONATE); TIN 2 ETHYLHEXANOIC ACID; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BIOCOMPATIBILITY; BIODEGRADATION; CATALYSIS; CONTROLLED STUDY; DEGRADATION KINETICS; DISSOLUTION; DRUG DELIVERY SYSTEM; FLOW KINETICS; GLASS TRANSITION TEMPERATURE; IMPLANT; IN VIVO STUDY; MACROPHAGE ACTIVATION; MALE; MOLECULAR WEIGHT; NONHUMAN; OXIDATION; POLYMERIZATION; PROTEIN HYDROLYSIS; RAT; RING OPENING; VISCOSITY;

ANIMALS; BIOCOMPATIBLE MATERIALS; DIOXANES; DRUG DELIVERY SYSTEMS; HYDROLYSIS; IMPLANTS, EXPERIMENTAL; MACROPHAGES; MATERIALS TESTING; MOLECULAR WEIGHT; OXIDATION-REDUCTION; POLYMERS; RATS; VISCOSITY;

RATTUS;

EID: 70049093130     PISSN: 16165187     EISSN: 16165195     Source Type: Journal    
DOI: 10.1002/mabi.200800318     Document Type: Article

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