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Volumn 40, Issue 4, 2009, Pages 374-379

Stress-up-regulated myocardial endothelin receptors are suppressed by chlorobenzyltetrahydroberberine CPU86017 and its RS chiral isomer

Author keywords

Chiral isomer; Chlorobenzyltetrahydroberberine; CPU86017; ETA; ETB; Isoproterenol; Oxidative stress

Indexed keywords

CHLOROBENZYLTETRAHYDROBERBERINE; CPU 86017; ENDOTHELIN RECEPTOR; ISOPRENALINE; PROPRANOLOL DERIVATIVE; UNCLASSIFIED DRUG;

EID: 69949184943     PISSN: 10005048     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (2)

References (20)
  • 1
    • 2442667616 scopus 로고    scopus 로고
    • Molecular determinants of altered contractility in heart failure
    • J
    • Wehrens XH, Marks AR. Molecular deter minants of altered contractility in heart failure[J]. Ann Med,2004,36(Suppl 1):70-80.
    • (2004) Ann Med , vol.36 , Issue.SUPPL. 1 , pp. 70-80
    • Wehrens, X.H.1    Marks, A.R.2
  • 2
    • 4444303576 scopus 로고    scopus 로고
    • Leptin induces hypertrophy via endothelin-1-reactive oxygen species pathway in cultured neonatal rat cardiomyocytes
    • J
    • Xu FP, Chen MS, Wang YZ, et al. Leptin induces hypertrophy via endothelin-1-reactive oxygen species pathway in cultured neonatal rat cardiomyocytes[J]. Circulation,2004,110(10):1 269-1 275.
    • (2004) Circulation , vol.110 , Issue.10 , pp. 1269-1275
    • Xu, F.P.1    Chen, M.S.2    Wang, Y.Z.3
  • 3
    • 33748952130 scopus 로고    scopus 로고
    • Up-regulated inflammatory factors endothelin, NFkappaB, TNFalpha and iNOS involved in exaggerated cardiac arrhythmias in 1-thyroxine-induced cardiomyopathy are suppressed by darusentan in rats
    • J
    • Xia HJ, Dai DZ, Dai Y. Up-regulated inflammatory factors endothelin , NFkappaB, TNFalpha and iNOS involved in exaggerated cardiac arrhythmias in 1-thyroxine-induced cardiomyopathy are suppressed by darusentan in rats[J]. Life Sci,2006,79(19):1 812-1 819.
    • (2006) Life Sci , vol.79 , Issue.19 , pp. 1812-1819
    • Xia, H.J.1    Dai, D.Z.2    Dai, Y.3
  • 4
    • 34249309636 scopus 로고    scopus 로고
    • Abrupt changes in FKBP12. 6 and SERCA2a expression contribute to sudden occurrence of ventricular fibrillation on reperfusion and are prevented by CPU86017
    • J
    • Na T, Huang ZJ, Dai DZ, et al. Abrupt changes in FKBP12. 6 and SERCA2a expression contribute to sudden occurrence of ventricular fibrillation on reperfusion and are prevented by CPU86017[J]. Acta Pharmacol Sin,2007,28(6):773-782.
    • (2007) Acta Pharmacol Sin , vol.28 , Issue.6 , pp. 773-782
    • Na, T.1    Huang, Z.J.2    Dai, D.Z.3
  • 5
    • 33847652782 scopus 로고    scopus 로고
    • CPU86017: A novel Class III antiarrhythmic agent with multiple actions at ion channels
    • J
    • Dai DZ. CPU86017: a novel Class III antiarrhythmic agent with multiple actions at ion channels[J]. Cardiovasc Drug Rev,2006,24(2):101-115.
    • (2006) Cardiovasc Drug Rev , vol.24 , Issue.2 , pp. 101-115
    • Dai, D.Z.1
  • 6
    • 56249140039 scopus 로고    scopus 로고
    • Long QT syndrome and short QT syndrome
    • J
    • Zareba W, Cygankiewicz I. Long QT syndrome and short QT syndrome[J]. Prog Cardiovasc Dis,2008,51(3):264-278.
    • (2008) Prog Cardiovasc Dis , vol.51 , Issue.3 , pp. 264-278
    • Zareba, W.1    Cygankiewicz, I.2
  • 7
    • 2942546069 scopus 로고    scopus 로고
    • Endothelin receptor antagonists in heart failure: Current status and future directions
    • J
    • Ertl G, Bauersachs J. Endothelin receptor antagonists in heart failure: current status and future directions[J]. Drugs,2004,64(10):1 029-1 040.
    • (2004) Drugs , vol.64 , Issue.10 , pp. 1029-1040
    • Ertl, G.1    Bauersachs, J.2
  • 8
    • 33748116170 scopus 로고    scopus 로고
    • Pitavastatin improves cardiac function and survival in association with suppression of the myocardial endothelin system in a rat model of hypertensive heart failure
    • J
    • Saka M, Obata K, Ichihara S, et al. Pitavastatin improves cardiac function and survival in association with suppression of the myocardial endothelin system in a rat model of hypertensive heart failure[J]. J Cardiovasc Pharmacol,2006,47(6):770-779.
    • (2006) J Cardiovasc Pharmacol , vol.47 , Issue.6 , pp. 770-779
    • Saka, M.1    Obata, K.2    Ichihara, S.3
  • 9
    • 50249098177 scopus 로고    scopus 로고
    • Induced ion currents and the endothelin pathway as targets for anti-arrhythmic agents
    • J
    • Dai DZ, Dai Y. Induced ion currents and the endothelin pathway as targets for anti-arrhythmic agents[J]. Curr Opin Investig Drugs,2008,9(9):1 001 -1 008.
    • (2008) Curr Opin Investig Drugs , vol.9 , Issue.9 , pp. 1001-1008
    • Dai, D.Z.1    Dai, Y.2
  • 10
    • 3042699908 scopus 로고    scopus 로고
    • Effects of endothelins on cardiac and vascular cells: New therapeutic target for the future
    • J
    • Mohácsi A.Magyar J, Tamás B, et al. Effects of endothelins on cardiac and vascular cells : new therapeutic target for the future[J]? Curr Vasc Pharmacol,2004,2(1):53-63.
    • (2004) Curr Vasc Pharmacol , vol.2 , Issue.1 , pp. 53-63
    • Mohácsi, A.1    Magyar, J.2    Tamás, B.3
  • 11
    • 0035253797 scopus 로고    scopus 로고
    • Endothelin and cardiac arrhythmias: Do endothelin antagonists have a therapeutic potential as antiarrhythmic drugs
    • J
    • Dura F, Barton M, Lüscher TF, et al. Endothelin and cardiac arrhythmias: do endothelin antagonists have a therapeutic potential as antiarrhythmic drugs[J]? Cardiovasc Res,2001,49(2):272-280.
    • (2001) Cardiovasc Res , vol.49 , Issue.2 , pp. 272-280
    • Dura, F.1    Barton, M.2    Lüscher, T.F.3
  • 12
    • 35649003917 scopus 로고    scopus 로고
    • Reversal of isoproterenol-induced downregulation of phospholamban and FKBP12. 6 by CPU0213-mediated antagonism of endothelin receptors
    • J
    • Feng Y, Tang XY, Dai DZ, et al. Reversal of isoproterenol-induced downregulation of phospholamban and FKBP12. 6 by CPU0213-mediated antagonism of endothelin receptors[J]. Acta Pharmacol Sin,2007,28(11):1 746-1 754.
    • (2007) Acta Pharmacol Sin , vol.28 , Issue.11 , pp. 1746-1754
    • Feng, Y.1    Tang, X.Y.2    Dai, D.Z.3
  • 13
    • 2942534124 scopus 로고    scopus 로고
    • Dispersion of ventricular mRNA of RyR2 and SERCA2 associated with arrhythmogenesis in rats
    • J
    • Wang HL, Dai DZ, Gao E, et al. Dispersion of ventricular mRNA of RyR2 and SERCA2 associated with arrhythmogenesis in rats[J]. Acta Pharmacol Sin,2004,25(6):738-743.
    • (2004) Acta Pharmacol Sin , vol.25 , Issue.6 , pp. 738-743
    • Wang, H.L.1    Dai, D.Z.2    Gao, E.3
  • 14
    • 33847031260 scopus 로고    scopus 로고
    • Contrasting actions of endothelin ET(A) and ET(B) receptors in cardiovascular disease
    • J
    • Schneider MP, Boesen EI, Pollock DM. Contrasting actions of endothelin ET(A) and ET(B) receptors in cardiovascular disease[J]. Anna Rev Pharmacol Toxicol,2007,47:731-759.
    • (2007) Anna Rev Pharmacol Toxicol , vol.47 , pp. 731-759
    • Schneider, M.P.1    Boesen, E.I.2    Pollock, D.M.3
  • 15
    • 21244456905 scopus 로고    scopus 로고
    • Endothelin-1 enhances oxidative stress, cell proliferation and reduces apoptosis in human umbilical vein endothelial cells: Role of ETB receptor, NADPH oxidase and caveolin-1
    • J
    • Dong F, Zhang X, Wold LE, et al. Endothelin-1 enhances oxidative stress, cell proliferation and reduces apoptosis in human umbilical vein endothelial cells: role of ETB receptor, NADPH oxidase and caveolin-1[J]. Br J Pharmacol,2005,145(3):323-333.
    • (2005) Br J Pharmacol , vol.145 , Issue.3 , pp. 323-333
    • Dong, F.1    Zhang, X.2    Wold, L.E.3
  • 16
    • 27744528050 scopus 로고    scopus 로고
    • Endothelin mediates superoxide production and vasoconstriction through activation of NADPH oxidase and uncoupled nitric-oxide synthase in the rat aorta
    • J
    • Loomis ED, Sullivan JC, Osmond DA, et al. Endothelin mediates superoxide production and vasoconstriction through activation of NADPH oxidase and uncoupled nitric-oxide synthase in the rat aorta[J]. J Pharmacol Exp Ther,2005,315(3):1 058-1 064.
    • (2005) J Pharmacol Exp Ther , vol.315 , Issue.3 , pp. 1058-1064
    • Loomis, E.D.1    Sullivan, J.C.2    Osmond, D.A.3
  • 17
    • 51849122365 scopus 로고    scopus 로고
    • Normalizing NADPH oxidase contributes to attenuating diabetic nephropathy by a dual endothelin receptor antagonist CPU0213 in rats
    • J
    • Xu M, Dai DZ, Dai Y, Normalizing NADPH oxidase contributes to attenuating diabetic nephropathy by a dual endothelin receptor antagonist CPU0213 in rats[J]. Am J Nephrol,2009,29(3):252-256.
    • (2009) Am J Nephrol , vol.29 , Issue.3 , pp. 252-256
    • Xu, M.1    Dai, D.Z.2    Dai, Y.3
  • 18
    • 34547193773 scopus 로고    scopus 로고
    • Stereoselectivity in drug metabolism
    • J
    • Lu H. Stereoselectivity in drug metabolism[J]. Expert Opin Drug Metab Toxicol,2007,3(2):149-158.
    • (2007) Expert Opin Drug Metab Toxicol , vol.3 , Issue.2 , pp. 149-158
    • Lu, H.1
  • 19
    • 29644432360 scopus 로고    scopus 로고
    • Difference in cardiovascalar activities of CPU-86017 between Rat and Rabbit by in and icv rentes, and potential relation to endotheliam
    • J
    • Ciamala CD, Wang ZZ, Dai DZ. Difference in cardiovascalar activities of CPU-86017 between Rat and Rabbit by in and icv rentes , and potential relation to endotheliam[J]. J Chin Pharm Univ,2002,33(5):428-433.
    • (2002) J Chin Pharm Univ , vol.33 , Issue.5 , pp. 428-433
    • Ciamala, C.D.1    Wang, Z.Z.2    Dai, D.Z.3
  • 20
    • 54249099098 scopus 로고    scopus 로고
    • CPU86017 and its isomers improve hypoxic pulmonary hypertension by attenuating increased ETA receptor expression and extracellular matrix accumulation
    • J
    • Li N, Dai DZ, Dai Y. CPU86017 and its isomers improve hypoxic pulmonary hypertension by attenuating increased ETA receptor expression and extracellular matrix accumulation[J]. Naunyn Schmiedebergs Arch Pharmacol,2008,378(5):541-552.
    • (2008) Naunyn Schmiedebergs Arch Pharmacol , vol.378 , Issue.5 , pp. 541-552
    • Li, N.1    Dai, D.Z.2    Dai, Y.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.